Compound Description

ID:   C0617 Common name:   Coptisine
IUPAC:  5,7,17,19-tetraoxa-13-azoniahexacyclo[11.11.0.02,10.04,8.015,23.016,20]tetracosa-1(13),2,4(8),9,14,16(20),21,23-octaene CAS:  NA
Chembl ID:   CHEMBL362071 Pubchem ID:   CID:72322
Formula:  C19H14NO4 TCM-ID:  TCMC3238
Smiles:  C1C[N+]2=C(C=C3C=CC4=C(C3=C2)OCO4)C5=CC6=C(C=C51)OCO6
Alias:

NA
Structure:

Related Targets  (Total: 7)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T38OH4 Caspase-1CASP1 P29466
A 1 Reference(s)
T68XO1 Indoleamine 2,3-dioxygenase 1IDO1 P14902
A 2 Reference(s)
T14V9R Dihydroorotate dehydrogenaseDHODH Q02127
A 1 Reference(s)
T21DZX Amine oxidase [flavin-containing] AMAOA P21397
B 1 Reference(s)
T49TDM Matrix metalloproteinase-9MMP9 P14780
C 1 Reference(s)
T31P1D Metalloproteinase inhibitor 1TIMP1 P01033
C 1 Reference(s)
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 3)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0706 Yan Hu Suo延胡索 YanhusuoCorydalis yanhusuo
H0006 Bai Qu Cai白屈菜 Greater celandineChelidonium majus
H1241 Huang Lian黄连 Coptis deltoideaCoptis chinensis