Target Description

Type Detail
Target ID T31P1D
Protein Name Metalloproteinase inhibitor 1
Uniprot ID P01033
Protein Name Alias Erythroid-potentiating activity;  EPA;  Fibroblast collagenase inhibitor;  Collagenase inhibitor;  Tissue inhibitor of metalloproteinases 1;  TIMP-1
Gene ID 7076
Gene Symbol TIMP1
Gene Alias CLGI;  TIMP
TTD NA
Pfam PF00965
GO
0031012:extracellular matrix

0031093:platelet alpha granule lumen

0043086:negative regulation of catalytic activity

0019221:cytokine-mediated signaling pathway

0044267:cellular protein metabolic process

0009725:response to hormone

0034097:response to cytokine

0071492:cellular response to UV-A

0002248:connective tissue replacement involved in inflammatory response wound healing

1901164:negative regulation of trophoblast cell migration

0008270:zinc ion binding

0008083:growth factor activity

0002576:platelet degranulation

0043066:negative regulation of apoptotic process

0030414:peptidase inhibitor activity

0051045:negative regulation of membrane protein ectodomain proteolysis

0005615:extracellular space

0005125:cytokine activity

1905049:negative regulation of metallopeptidase activity

0022617:extracellular matrix disassembly

0010033:response to organic substance

0070062:extracellular exosome

0008191:metalloendopeptidase inhibitor activity

0005576:extracellular region

0001775:cell activation

0005604:basement membrane

0010951:negative regulation of endopeptidase activity

0002020:protease binding

0043434:response to peptide hormone

0051216:cartilage development

0007568:aging

0008284:positive regulation of cell population proliferation

2001044:regulation of integrin-mediated signaling pathway

0043687:post-translational protein modification

0005788:endoplasmic reticulum lumen

PDB 3MA2 ; 1LQN ; 1UEA ; 1OO9 ; 3V96 ; 6N9D ; 1D2B ; 2J0T ; 6MAV
Drugbank NA
KEGG hsa:7076

Related Compounds  (Total: 18)

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C0035
Name: Dronabinol
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C0047
Name: Epigalocatechin Gallate
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C0101
Name: Genistein
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C0249
Name: Nobiletin
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C0305
Name: Phorbol Myristate Acetate


Related Herbs  (Total: 143)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0809 Zhi Mu知母 Common anemarrhenaAnemarrhena asphodeloides
H0189 Lv Cha绿茶 Green teaFolium camelliae sinensis
H0556 Tie Xian Cao铁线草 NAAdiantum capillus-veneris
H0802 Zhi Geng枳梗 NACitrus aurantium
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H1061 Bai He百合 LilyLilium brownii
H0818 Zhi Zi栀子 Cape jasmine fruitGardenia jasminoides
H0804 Zhi Ke枳壳 Seville ora nge unripe fruitCitrus aurantium
H0424 Shan Zhi山栀 Cape jasmineGardenia jasminoides
H0029 Jiang Huang Lian姜黄连 Coptis deltoideaCoptis chinensis
H1072 Gan Cao Gao甘草膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0878 Ba Dou Shuang巴豆霜 Defatted croton seed powderCroton tiglium
H0813 Zhi Shi枳实 Seville orange young fruitCitrus aurantium
H0302 Ou Fen藕粉 Hindu lotus large rhizomeNelumbo nucifera
H0560 Cao Bei Mu草贝母 Indian iphigeniaIphigenia indica
H0637 Cha Ye茶叶 Common teaCamellia sinensis
H1075 Gan Cao Liu Jin Gao甘草流浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0026 Jiang Soybean pasteGlycine max
H0016 Ji Xue Cao积雪草 Asiatic pennywortCentella asiatica
H1073 Gan Cao Jie甘草节 Glycyrrhiza uralensis fischGlycyrrhiza uralensis
H1095 Ge Gen Gan Jin Gao葛根干浸膏 Lobed kudzuvine rootPueraria lobata
H0761 Yu Jin郁金 AromaticTurmericCurcuma aromatica
H0944 Dan Dou Gu淡豆鼓 NAGlycine max
H1068 Bai He Liu Jin Gao百合流浸膏 LilyLilium brownii
H0958 Dang Shen党参 Pilose asiabellCodonopsis pilosula
H0275 Mu Zei木贼 Common scouring rushEquisetum hiemale
H1124 Guang Jin Qian Cao广金钱草 Snowbellleaf tickcloverDesmodium styracifolium
H1225 Huai Mi槐米 NASophora japonica
H1167 He Tao核桃 English walnut seedSemen juglandis
H1244 Huang Miao黄苗 NATaraxacum mongolicum
H1029 Fang Er Cha方儿茶 khair in hindiSenegalia catechu
H1034 Fei Yang Cao飞杨草 NAEuphorbia hirta
H0391 Sang Pi桑皮 Prepared root-bark white mulberryMorus alba
H0258 Mo Han Lian墨旱莲 YerbadetajoEclipta prostrata
H0028 Jiang Huang姜黄 Common turmericCurcuma longa
H0925 Da Fu Zi大腹子 Areca palmAreca catechu
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H0952 Dan Xiang Chi淡香豉 NAGlycine max
H0396 Sang Ye桑叶 White mulberry leafMorus alba
H1222 Huai Hua槐花 flower bud of japanese pagodatreeSophora japonica
H1227 Huai Zhi槐枝 NASophora japonica
H1070 Gan Cao Gan Gao Fen甘草干膏粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0887 Chuan Xin Lian Gan Jin Gao穿心莲干浸膏 Common andrographisAndrographis paniculata
H0692 Xue Ren Shen血人参 NALespedeza bicolor
H0289 Niu Bang Zi牛蒡子 Great burdock fruitArctium lappa
H0951 Dan Shen Jin Gao丹参浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H1094 Ge Gen葛根 Lobed kudzuvine rootPueraria lobata
H0604 Wu Wei Teng五味藤 NASecuridaca inappendiculata
H0979 Di Yu地榆 Garden burnetSanguisorba officinalis
H0574 Cao Dou Kou草豆蔻 Katsumada galangalAlpinia katsumadai
H0353 Que Mei Teng Gen雀梅藤根 Hedge sageretiaSageretia thea
H0785 Ze Xi Huang Lian择细黄连 Coptis deltoideaCoptis chinensis
H0031 Jiang Tan姜炭 Soybean pasteGlycine max
H0141 Lian Zi Xin莲子心 Hindu lotus plumuleNelumbo nucifera
H1067 Gan Cao Fen甘草粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H1176 Hei Hu Jiao黑胡椒 Black pepperPiper nigrum
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0652 Xiang Yuan Pi香橼皮 Wilson citronCitrus medica
H0129 Le Xian Cai勒苋菜 NAAmaranthus spinosus
H1224 Huai Jiao槐角 pod of japanese pagodatreeSophora japonica
H0484 Shui Fei Ji水飞蓟 St marysSilybum marianum
H0304 Ou Pian藕片 Hindu lotus large rhizomeNelumbo nucifera
H1231 Huang Bai Tan黄柏炭 Amur corktreePhellodendron amurense
H0077 Jiu EthanolVinum
H1096 Ge Hua葛花 flower bud of lobed kudzuvinePueraria lobata
H0140 Lian Zi莲子 Hindu lotus seedNelumbo nucifera
H1242 Huang Lian Gan Jin Gao黄连干浸膏 Coptis deltoideaCoptis chinensis
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0949 Dan Shen丹参 The root of red-rooted salviaSalvia miltiorrhiza
H0889 Chuan Xin Lian Jin Gao穿心莲浸膏 Common andrographisAndrographis paniculata
H1077 Bai Hu Jiao白胡椒 white pepperPiper nigrum
H0895 Chuan Yu Jin川郁金 TurmericCurcuma longa
H0721 Yang Mei Gen杨梅根 Myrica rubra sieb. et zuccMyrica rubra
H0706 Yan Hu Suo延胡索 YanhusuoCorydalis yanhusuo
H1007 Dou You豆油 Soybean oilGlycine max
H0805 Zhi Ke Gan Jin Gao枳壳干浸膏 Seville ora nge unripe fruitCitrus aurantium
H1016 Du Zhong Tan杜仲炭 EucommiaEucommia ulmoides
H0130 Lei Gong Teng雷公藤 Common threewingnutTripterygium wilfordii
H1074 Gan Cao Jin Gao甘草浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1214 Hua Jiao花椒 Bunge pricklyashZanthoxylum bungeanum
H0819 Zhi Zi Jin Gao栀子浸膏 Cape jasmine fruitGardenia jasminoides
H1017 Du Zhong Ye杜仲叶 Eucommia leafEucommia ulmoides
H1069 Gan Cao Gan Gao甘草干膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0093 Ju Pi橘皮 Tangerine pericarpCitrus reticulata
H0995 Dong Chong Xia Cao冬虫夏草 AwetoCordyceps sinensis
H0533 Teng Ku Shen藤苦参 NASophora flavescens
H1204 Hu Jiao胡椒 Black pepperPiper nigrum
H0852 Zi Tan紫檀 Burmacoast padaukPterocarpus indicus
H0827 Zhu Hong Jun竹红菌 Bambusa hypocrella*Hypocrella bambusae
H0760 Yu Huang Lian萸黄连 Coptis deltoideaCoptis chinensis
H1240 Huang Jing Zi黄荆子 NAVitex negundo
H0682 Xiong Huang Lian雄黄连 Coptis deltoideaCoptis chinensis
H0314 Pu Gong Ying蒲公英 Mongolian dandelionTaraxacum mongolicum
H0315 Pu Gong Ying Jin Gao蒲公英浸膏 Mongolian dandelionTaraxacum mongolicum
H0869 Ba Dou巴豆 Pu rging crotonCroton tiglium
H0886 Chuan Xin Lian穿心莲 Common andrographisAndrographis paniculata
H0872 Chuan Huang Lian川黄连 rhizome of chinese goldthreadCoptis chinensis
H1243 Huang Lian Xu黄连须 Coptis deltoideaCoptis chinensis
H0960 Dang Shen Qing Gao党参清膏 Root of hairy asiabellCodonopsis pilosula
H0888 Ba Dou Ye巴豆叶 Pu rging crotonCroton tiglium
H1241 Huang Lian黄连 Coptis deltoideaCoptis chinensis
H1174 Hei Da Dou黑大豆 Black soyabeanGlycine max
H0758 Cheng Pi橙皮 Bitter orangeCitrus aurantium
H0950 Dan Shen Gan Jin Gao丹参干浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0166 Long Kui龙葵 Black nightshadeSolanum nigrum
H1015 Du Zhong杜仲 EucommiaEucommia ulmoides
H0082 Jiu Huang Lian酒黄连 Coptis deltoideaCoptis chinensis
H0240 Mi Gan Cao蜜甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0284 Nan She Teng南蛇藤 Oriental bittersweetCelastrus orbiculatus
H1066 Gan Cao甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1115 Guan Huang Bai关黄柏 Amur cork treePhellodendron amurense
H0132 Li Lu藜芦 Black falsehelleboreVeratrum nigrum
H0006 Bai Qu Cai白屈菜 Greater celandineChelidonium majus
H1230 Huang Bai Fen黄柏粉 Amur corktreePhellodendron amurense
H0088 Ju He橘核 Tangerine seedCitrus reticulata
H0408 Bing Lang槟榔 BetenutpalmAreca catechu
H1168 He Tao Ren核桃仁 English walnut seedSemen juglandis
H0938 Da Suan大蒜 GarlicAllium sativum
H0027 Jiang Gao姜膏 Soybean pasteGlycine max
H1004 Bai Cha白茶 White teaCamellia sinensis
H0651 Xiang Yuan香橼 Wilson citronCitrus medica
H1164 He Geng荷梗 Hindu lotus petioleNelumbo nucifera
H0704 Yan Guan Huang Bai盐关黄柏 Amur cork treePhellodendron amurense
H0397 Sang Zhi桑枝 White mulberry branchMorus alba
H0890 Chuan Xin Lian Nong Suo Ye穿心莲浓缩液 Common andrographisAndrographis paniculata
H0301 Ou Hindu lotus large rhizomeNelumbo nucifera
H0444 Sheng Gan Cao生甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0906 Ci Wan刺苋 spiny amaranthAmaranthus spinosus
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H1228 Huang Bai黄柏 Amur corktreePhellodendron amurense
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0111 Ku Shen苦参 Lightyellow sophoraSophora flavescens
H0575 Tu Ku Shen土苦参 all-grass of hooker wingheadSophora flavescens
H0003 Huo Ma Ren火麻仁 Hemp fimble seedCannabis sativa
H0582 Cao Dou Kou Ren草豆蔻仁 Katsumada galangalAlpinia katsumadai
H0792 Zhang Yu章鱼 Common atlantic octopusOctopus vulgaris
H1169 He Ye荷叶 Hindu lotus leafNelumbo nucifera
H0571 Tu Gan Cao土甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1080 Gan Ge干葛 Lobed kudzuvine rootPueraria lobata
H1071 Gan Cao Gan Jin Gao甘草干浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0633 Xia Tian Wu夏天无 Decumbent corydalisCorydalis decumbens
H0980 Di Yu Tan地榆炭 Garden burnetSanguisorba officinalis
H0204 Ma Ren麻仁 NACannabis sativa