HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T05O6O	Estrogen receptor beta	ESR2	Q92731	10 Reference(s)
T22JG3	Fibroblast growth factor receptor 2	FGFR2	P21802	1 Reference(s)
T74JJN	Fatty acid synthase	FASN	P49327	1 Reference(s)
T01QLH	Estrogen receptor	ESR1	P03372	11 Reference(s)
T53KY7	Cystic fibrosis transmembrane conductance regulator	CFTR	P13569	2 Reference(s)
T69XEM	Tyrosine-protein kinase SYK	SYK	P43405	1 Reference(s)
T49ORJ	Peroxisome proliferator-activated receptor alpha	PPARA	Q07869	2 Reference(s)
T27LA6	DNA	DNMT1	P26358	1 Reference(s)
T25UYT	Dual specificity mitogen-activated protein kinase kinase 4	MAP2K4	P45985	1 Reference(s)
T43N2D	Epidermal growth factor receptor	EGFR	P00533	3 Reference(s)
T20JZ2	Androgen receptor	AR	P10275	3 Reference(s)
T70NYW	Fibroblast growth factor receptor 4	FGFR4	P22455	1 Reference(s)
T03VS9	Protein-tyrosine kinase 2-beta	PTK2B	Q14289	3 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	4 Reference(s)
T12BGL	Cytochrome P450 2A6	CYP2A6	P11509	1 Reference(s)
T24VJT	GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase	H6PD	O95479	1 Reference(s)
T93YV8	Tumor necrosis factor receptor superfamily member 11B	TNFRSF11B	O00300	3 Reference(s)
T07TRP	Short transient receptor potential channel 5	TRPC5	Q9UL62	1 Reference(s)
T97FEF	Broad substrate specificity ATP-binding cassette transporter ABCG2	ABCG2	Q9UNQ0	1 Reference(s)
T15RPU	Kinesin-like protein KIF20A	KIF20A	O95235	1 Reference(s)
T68DAN	Histone deacetylase 9	HDAC9	Q9UKV0	1 Reference(s)
T49CBW	Class E basic helix-loop-helix protein 40	BHLHE40	O14503	1 Reference(s)
T40DIM	Corticosteroid 11-beta-dehydrogenase isozyme 1	HSD11B1	P28845	1 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	7 Reference(s)
T23P74	Caspase-9	CASP9	P55211	2 Reference(s)
T71BDH	Mitogen-activated protein kinase 14	MAPK14	Q16539	2 Reference(s)
T28ULC	NA	MIR22	NA	1 Reference(s)
T49TDM	Matrix metalloproteinase-9	MMP9	P14780	3 Reference(s)
T11BI7	Toll-like receptor 4	TLR4	O00206	1 Reference(s)
T16MRU	NACHT, LRR and PYD domains-containing protein 3	NLRP3	Q96P20	2 Reference(s)
T88TDZ	RAC-alpha serine/threonine-protein kinase	AKT1	P31749	4 Reference(s)
T16A2X	Catalase	CAT	P04040	2 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	3 Reference(s)
T65JYL	C-X-C motif chemokine 2	CXCL2	P19875	1 Reference(s)
T53AOE	Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide	TGFB1	P01137	4 Reference(s)
T32OC4	Aldehyde dehydrogenase, mitochondrial	ALDH2	P05091	3 Reference(s)
T91W8B	All-trans-retinol dehydrogenase [NAD(+)] ADH4	ADH4	P08319	1 Reference(s)
T44WZO	Alcohol dehydrogenase 1C	ADH1C	P00326	1 Reference(s)
T12T4H	Brain-derived neurotrophic factor	BDNF	P23560	1 Reference(s)
T50SX0	Nuclear receptor subfamily 1 group I member 2	NR1I2	O75469	2 Reference(s)
T63YAO	Caveolin-1	CAV1	Q03135	2 Reference(s)
T12PIB	Lysosomal alpha-glucosidase	GAA	P10253	1 Reference(s)
T54G8J	Protein kinase C delta type	PRKCD	Q05655	2 Reference(s)
T22MME	Quinone oxidoreductase	CRYZ	Q08257	1 Reference(s)
T53G91	Nischarin	NISCH	Q9Y2I1	1 Reference(s)
T49WXY	DNA nucleotidylexotransferase	DNTT	P04053	1 Reference(s)
T93SFQ	NAD-dependent protein deacetylase sirtuin-1	SIRT1	Q96EB6	1 Reference(s)
T61OY3	UDP-glucuronosyltransferase 1A1	UGT1A1	P22309	1 Reference(s)
T19JEU	Beta-galactosidase	GLB1	P16278	1 Reference(s)
T67HAF	Signal transducer and activator of transcription 1-alpha/beta	STAT1	P42224	2 Reference(s)
T42XY2	Insulin-like growth factor 1 receptor	IGF1R	P08069	2 Reference(s)
T67ZT3	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	PTEN	P60484	1 Reference(s)
T42EAZ	Vascular endothelial growth factor A	VEGFA	P15692	4 Reference(s)
T44LWL	Transcription factor p65	RELA	Q04206	6 Reference(s)
T09H2Z	Nitric oxide synthase, inducible	NOS2	P35228	4 Reference(s)
T07TMB	Cyclin-dependent kinase 1	CDK1	P06493	3 Reference(s)
T78VUO	RAF proto-oncogene serine/threonine-protein kinase	RAF1	P04049	2 Reference(s)
T64W2K	Cyclin-dependent kinase inhibitor 1	CDKN1A	P38936	6 Reference(s)
T24LXT	G2/mitotic-specific cyclin-B1	CCNB1	P14635	4 Reference(s)
T20NCI	Serine-protein kinase ATM	ATM	Q13315	1 Reference(s)
T28EY5	Serine/threonine-protein kinase Chk2	CHEK2	O96017	2 Reference(s)
T58J2Y	Peroxisome proliferator-activated receptor gamma	PPARG	P37231	1 Reference(s)
T64BTV	Interleukin-1 beta	IL1B	P01584	1 Reference(s)
T17UP9	C-C motif chemokine 2	CCL2	P13500	2 Reference(s)
T54CIF	Interleukin-8	CXCL8	P10145	2 Reference(s)
T10HL8	Intercellular adhesion molecule 1	ICAM1	P05362	2 Reference(s)
T08Q7W	Prostaglandin G/H synthase 2	PTGS2	P35354	4 Reference(s)
T59IKQ	Vascular cell adhesion protein 1	VCAM1	P19320	3 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	3 Reference(s)
T86UXL	Cyclin-A2	CCNA2	P20248	1 Reference(s)
T68NCI	Aldo-keto reductase family 1 member B1	AKR1B1	P15121	1 Reference(s)
T26KIE	Transcription factor AP-1	JUN	P05412	4 Reference(s)
T63GUB	Proto-oncogene c-Fos	FOS	P01100	3 Reference(s)
T77PFO	Histone deacetylase 6	HDAC6	Q9UBN7	1 Reference(s)
T26UZV	Dual specificity mitogen-activated protein kinase kinase 5	MAP2K5	Q13163	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	4 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	4 Reference(s)
T44S1A	Apolipoprotein A-I	APOA1	P02647	1 Reference(s)
T54VQA	Cyclin-dependent kinase inhibitor 2A	CDKN2A	P42771	1 Reference(s)
T64UH1	Nitric oxide synthase, endothelial	NOS3	P29474	2 Reference(s)
T88AJI	Hypoxia-inducible factor 1-alpha	HIF1A	Q16665	1 Reference(s)
T96OOK	Signal transducer and activator of transcription 3	STAT3	P40763	2 Reference(s)
T38K2W	Receptor tyrosine-protein kinase erbB-2	ERBB2	P04626	2 Reference(s)
T79A7K	Protein PML	PML	P29590	1 Reference(s)
T19Z2N	Nuclear receptor corepressor 1	NCOR1	O75376	1 Reference(s)
T68BGR	Glial fibrillary acidic protein	GFAP	P14136	1 Reference(s)
T25NSJ	Mitogen-activated protein kinase 3	MAPK3	P27361	1 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	1 Reference(s)
T31P1D	Metalloproteinase inhibitor 1	TIMP1	P01033	2 Reference(s)
T24U57	E-selectin	SELE	P16581	1 Reference(s)
T39M81	DNA-(apurinic or apyrimidinic site) endonuclease	APEX1	P27695	1 Reference(s)
T05WU9	Serine/threonine-protein phosphatase 2A activator	PTPA	Q15257	1 Reference(s)
T98QOA	DNA-dependent protein kinase catalytic subunit	PRKDC	P78527	1 Reference(s)
T02QBS	Cytochrome P450 1A2	CYP1A2	P05177	2 Reference(s)
T79TJS	Caveolin-3	CAV3	P56539	1 Reference(s)
T17E95	Protein kinase C gamma type	PRKCG	P05129	1 Reference(s)
T21DZX	Amine oxidase [flavin-containing] A	MAOA	P21397	1 Reference(s)
T83YZD	Acetylcholinesterase	ACHE	P22303	2 Reference(s)
T04AHN	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2	HSD3B2	P26439	1 Reference(s)
T84W8G	Aryl hydrocarbon receptor	AHR	P35869	1 Reference(s)
T23K1O	Calmodulin	CALM3;CALML2;CAM3;CAMC;CAMIII	P62158	1 Reference(s)
T09TS5	Gamma-aminobutyric acid type B receptor subunit 1	GABBR1	Q9UBS5	1 Reference(s)
T74ETU	Steroid 21-hydroxylase	CYP21A2	P08686	1 Reference(s)
T50WUM	Leucine--tRNA ligase, cytoplasmic	LARS1	Q9P2J5	1 Reference(s)
T30V3R	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	HSD3B1	P14060	2 Reference(s)
T29GH0	Trefoil factor 1	TFF1	P04155	3 Reference(s)
T98JPP	Carnitine O-palmitoyltransferase 1, liver isoform	CPT1A	P50416	1 Reference(s)
T50V79	Interleukin-4	IL4	P05112	1 Reference(s)
T73S71	Apolipoprotein B-100	APOB	P04114	1 Reference(s)
T49PL1	Low-density lipoprotein receptor	LDLR	P01130	3 Reference(s)
T13KGH	Tyrosinase	TYR	P14679	1 Reference(s)
T79KQO	NF-kappa-B inhibitor alpha	NFKBIA	P25963	1 Reference(s)
T90XMB	Ubiquitin carboxyl-terminal hydrolase 5	USP5	P45974	1 Reference(s)
T40G6B	Prostaglandin reductase 1	PTGR1	Q14914	1 Reference(s)
T50WOV	ATP-dependent translocase ABCB1	ABCB1	P08183	1 Reference(s)
T38N69	Lymphokine-activated killer T-cell-originated protein kinase	PBK	Q96KB5	1 Reference(s)
T06PVX	E3 ubiquitin-protein ligase Mdm2	MDM2	Q00987	1 Reference(s)
T42K6K	M-phase inducer phosphatase 3	CDC25C	P30307	1 Reference(s)
T89VFL	Alpha-crystallin B chain	CRYAB	P02511	1 Reference(s)
T04A2Q	Serine/threonine-protein kinase PLK1	PLK1	P53350	1 Reference(s)
T82S6C	Hexokinase-4	GCK	P35557	1 Reference(s)
T00F43	Mediator of DNA damage checkpoint protein 1	MDC1	Q14676	1 Reference(s)
T21YK3	Cell division cycle protein 20 homolog	CDC20	Q12834	1 Reference(s)
T75I26	Mitotic checkpoint serine/threonine-protein kinase BUB1	BUB1	O43683	1 Reference(s)
T21Q0D	3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMGCR	P04035	2 Reference(s)
T13I7C	Transforming growth factor beta-2 proprotein	TGFB2	P61812	1 Reference(s)
T04WT7	Fibronectin	FN1	P02751	1 Reference(s)
T03G09	Tumor necrosis factor ligand superfamily member 11	TNFSF11	O14788	2 Reference(s)
T34N64	NA	MIR29B1	NA	1 Reference(s)
T30NJL	Electrogenic sodium bicarbonate cotransporter 1	SLC4A4	Q9Y6R1	1 Reference(s)
T33JS5	CCN family member 2	CCN2	P29279	2 Reference(s)
T88MR0	Solute carrier family 26 member 6	SLC26A6	Q9BXS9	1 Reference(s)
T91MKC	Runt-related transcription factor 2	RUNX2	Q13950	1 Reference(s)
T31SX8	Bone morphogenetic protein 2	BMP2	P12643	1 Reference(s)
T17X6I	DNA fragmentation factor subunit alpha	DFFA	O00273	1 Reference(s)
T16S8T	Baculoviral IAP repeat-containing protein 7	BIRC7	Q96CA5	1 Reference(s)
T46AQJ	Glutathione S-transferase P	GSTP1	P09211	1 Reference(s)
T49A2A	Sodium/hydrogen exchanger 1	SLC9A1	P19634	1 Reference(s)
T25SPW	Sodium/hydrogen exchanger 2	SLC9A2	Q9UBY0	1 Reference(s)
T09HVO	Sodium/hydrogen exchanger 3	SLC9A3	P48764	1 Reference(s)
T33BF9	DNA	DNMT3B	Q9UBC3	1 Reference(s)
T76B0A	Gap junction alpha-1 protein	GJA1	P17302	1 Reference(s)
T74V1Z	Dual specificity mitogen-activated protein kinase kinase 7	MAP2K7	O14733	1 Reference(s)
T45G32	Proto-oncogene tyrosine-protein kinase Src	SRC	P12931	1 Reference(s)
T72BXP	Platelet endothelial cell adhesion molecule	PECAM1	P16284	1 Reference(s)
T24LWC	Sodium-dependent dopamine transporter	SLC6A3	Q01959	1 Reference(s)
T35QZO	Cytochrome c	CYCS	P99999	2 Reference(s)
T89SY7	Zinc finger and BTB domain-containing protein 16	ZBTB16	Q05516	1 Reference(s)
T92FAW	Dual specificity protein phosphatase 1	DUSP1	P28562	1 Reference(s)
T73LPO	Poly [ADP-ribose] polymerase 1	PARP1	P09874	2 Reference(s)
T51WML	Glutamate receptor 1	GRIA1	P42261	1 Reference(s)
T30D9G	Superoxide dismutase [Cu-Zn]	SOD1	P00441	1 Reference(s)
T90XYZ	C-reactive protein	CRP	P02741	1 Reference(s)
T13QI6	Aldo-keto reductase family 1 member A1	AKR1A1	P14550	1 Reference(s)
T33OSQ	Sterol regulatory element-binding protein 1	SREBF1	P36956	1 Reference(s)
T71GZE	UDP-glucuronosyltransferase 2B28	UGT2B28	Q9BY64	1 Reference(s)
T07NZK	Low affinity immunoglobulin epsilon Fc receptor	FCER2	P06734	1 Reference(s)
T11GHO	Transforming protein RhoA	RHOA	P61586	1 Reference(s)
T34AYH	Solute carrier family 52, riboflavin transporter, member 1	SLC52A1	Q9NWF4	1 Reference(s)
T36I66	Metallothionein-2	MT2A	P02795	1 Reference(s)
T90ZS8	Endothelin-converting enzyme 1	ECE1	P42892	1 Reference(s)
T16IWB	Growth arrest and DNA damage-inducible protein GADD45 alpha	GADD45A	P24522	1 Reference(s)
T29CYD	BRCA1-associated RING domain protein 1	BARD1	Q99728	1 Reference(s)
T41SFE	Histone acetyltransferase p300	EP300	Q09472	1 Reference(s)
T57R3V	Proliferation marker protein Ki-67	MKI67	P46013	1 Reference(s)
T82I76	Ubiquitin carboxyl-terminal hydrolase BAP1	BAP1	Q92560	1 Reference(s)
T82S9G	DNA repair protein RAD51 homolog 1	RAD51	Q06609	1 Reference(s)
T53QOD	ATP synthase subunit beta, mitochondrial	ATP5F1B	P06576	1 Reference(s)
T63SUZ	NADH-ubiquinone oxidoreductase chain 6	MT-ND6	P03923	1 Reference(s)
T85AXP	Cytochrome P450 3A4	CYP3A4	P08684	1 Reference(s)
T33OPP	Interleukin-6	IL6	P05231	1 Reference(s)
T46HRF	Growth hormone receptor	GHR	P10912	1 Reference(s)
T35FQV	Microsomal triglyceride transfer protein large subunit	MTTP	P55157	1 Reference(s)
T70SFS	Superoxide dismutase [Mn], mitochondrial	SOD2	P04179	1 Reference(s)
T28B0B	Monocarboxylate transporter 8	SLC16A2	P36021	1 Reference(s)
T53GFX	Arginase-1	ARG1	P05089	1 Reference(s)
T80GUN	72 kDa type IV collagenase	MMP2	P08253	1 Reference(s)
T63BQU	Cytochrome P450 1A1	CYP1A1	P04798	1 Reference(s)
T31MUM	5,6-dihydroxyindole-2-carboxylic acid oxidase	TYRP1	P17643	1 Reference(s)
T82G5G	L-dopachrome tautomerase	DCT	P40126	1 Reference(s)
T89A2U	Hsp90 co-chaperone Cdc37	CDC37	Q16543	1 Reference(s)
T91AIW	Receptor-type tyrosine-protein kinase FLT3	FLT3	P36888	1 Reference(s)
T95K8Q	Intestinal-type alkaline phosphatase	ALPI	P09923	1 Reference(s)

Herb ID: H1095	Chinese Character: 葛根干浸膏
English Name: Lobed kudzuvine root	Latin Name: Pueraria lobata
Chinese Pin Yin : Ge Gen Gan Jin Gao	TCM-ID: TCMH678
Therapeutic Function in Chinese : NA	Therapeutic Function in English: NA
Herb Function: NA

Herb Description

Related Targets (Total: 183)

Related Compounds (Total: 9)