Target Description
| Type | Detail |
|---|---|
| Target ID | T09HVO |
| Protein Name | Sodium/hydrogen exchanger 3 |
| Uniprot ID |
P48764 |
| Protein Name Alias | Na(+)/H(+) exchanger 3; NHE-3; Solute carrier family 9 member 3 |
| Gene ID |
6550 |
| Gene Symbol | SLC9A3 |
| Gene Alias | NHE3 |
| TTD | T92403: Successful target |
| Pfam | PF00999 |
| GO |
0005886:plasma membrane
0016324:apical plasma membrane 0015386:potassium:proton antiporter activity 0005903:brush border 0071805:potassium ion transmembrane transport 0098719:sodium ion import across plasma membrane 0006811:ion transport 0030165:PDZ domain binding 0051453:regulation of intracellular pH 0009986:cell surface 0070062:extracellular exosome 0016021:integral component of membrane 0031526:brush border membrane 0015385:sodium:proton antiporter activity |
| PDB | NA |
| Drugbank | DB11761 |
| KEGG | hsa:6550 |
Related Compounds (Total: 7)
C0034
Name: Dopamine
C0101
Name: Genistein
C0255
Name: Norepinephrine
C1171
Name: Berberine
C1182
Name: Bicarbonate
Related Herbs (Total: 82)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1163 | He Bao Cao | 荷包草 | NA | Lamprocapnos spectabilis |
| H1228 | Huang Bai | 黄柏 | Amur corktree | Phellodendron amurense |
| H1073 | Gan Cao Jie | 甘草节 | Glycyrrhiza uralensis fisch | Glycyrrhiza uralensis |
| H1124 | Guang Jin Qian Cao | 广金钱草 | Snowbellleaf tickclover | Desmodium styracifolium |
| H1231 | Huang Bai Tan | 黄柏炭 | Amur corktree | Phellodendron amurense |
| H1095 | Ge Gen Gan Jin Gao | 葛根干浸膏 | Lobed kudzuvine root | Pueraria lobata |
| H0575 | Tu Ku Shen | 土苦参 | all-grass of hooker winghead | Sophora flavescens |
| H0979 | Di Yu | 地榆 | Garden burnet | Sanguisorba officinalis |
| H0732 | Ye Mu Dan | 野牡丹 | Common melastoma | Melastoma candidum |
| H0031 | Jiang Tan | 姜炭 | Soybean paste | Glycine max |
| H1241 | Huang Lian | 黄连 | Coptis deltoidea | Coptis chinensis |
| H1115 | Guan Huang Bai | 关黄柏 | Amur cork tree | Phellodendron amurense |
| H0760 | Yu Huang Lian | 萸黄连 | Coptis deltoidea | Coptis chinensis |
| H1068 | Bai He Liu Jin Gao | 百合流浸膏 | Lily | Lilium brownii |
| H0652 | Xiang Yuan Pi | 香橼皮 | Wilson citron | Citrus medica |
| H0111 | Ku Shen | 苦参 | Lightyellow sophora | Sophora flavescens |
| H1080 | Gan Ge | 干葛 | Lobed kudzuvine root | Pueraria lobata |
| H0995 | Dong Chong Xia Cao | 冬虫夏草 | Aweto | Cordyceps sinensis |
| H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H1230 | Huang Bai Fen | 黄柏粉 | Amur corktree | Phellodendron amurense |
| H1174 | Hei Da Dou | 黑大豆 | Black soyabean | Glycine max |
| H0293 | Niu Jiao Tan | 牛角炭 | Buffalo horn | Bubalus bubalis |
| H0082 | Jiu Huang Lian | 酒黄连 | Coptis deltoidea | Coptis chinensis |
| H0952 | Dan Xiang Chi | 淡香豉 | NA | Glycine max |
| H1242 | Huang Lian Gan Jin Gao | 黄连干浸膏 | Coptis deltoidea | Coptis chinensis |
| H1069 | Gan Cao Gan Gao | 甘草干膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1226 | Huai Shan Yao | 淮山药 | rhizome of biglcaf yam | Rhizoma dioscoreae |
| H0291 | Niu Jiao Fen | 牛角粉 | Buffalo horn | Bubalus bubalis |
| H0026 | Jiang | 姜 | Soybean paste | Glycine max |
| H0240 | Mi Gan Cao | 蜜甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1074 | Gan Cao Jin Gao | 甘草浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0444 | Sheng Gan Cao | 生甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0027 | Jiang Gao | 姜膏 | Soybean paste | Glycine max |
| H0906 | Ci Wan | 刺苋 | spiny amaranth | Amaranthus spinosus |
| H0944 | Dan Dou Gu | 淡豆鼓 | NA | Glycine max |
| H0704 | Yan Guan Huang Bai | 盐关黄柏 | Amur cork tree | Phellodendron amurense |
| H1222 | Huai Hua | 槐花 | flower bud of japanese pagodatree | Sophora japonica |
| H0533 | Teng Ku Shen | 藤苦参 | NA | Sophora flavescens |
| H1071 | Gan Cao Gan Jin Gao | 甘草干浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1225 | Huai Mi | 槐米 | NA | Sophora japonica |
| H1007 | Dou You | 豆油 | Soybean oil | Glycine max |
| H1072 | Gan Cao Gao | 甘草膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1075 | Gan Cao Liu Jin Gao | 甘草流浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0029 | Jiang Huang Lian | 姜黄连 | Coptis deltoidea | Coptis chinensis |
| H0571 | Tu Gan Cao | 土甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0852 | Zi Tan | 紫檀 | Burmacoast padauk | Pterocarpus indicus |
| H1067 | Gan Cao Fen | 甘草粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0643 | Xiang Jiao | 橡胶 | Rubber | Musa paradisiaca var. sapientum |
| H0980 | Di Yu Tan | 地榆炭 | Garden burnet | Sanguisorba officinalis |
| H0292 | Niu Jiao Jian Fen | 牛角尖粉 | Buffalo horn | Bubalus bubalis |
| H1214 | Hua Jiao | 花椒 | Bunge pricklyash | Zanthoxylum bungeanum |
| H0084 | Jiu Li Xiang | 九里香 | Common jasminorange | Murraya paniculata |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0129 | Le Xian Cai | 勒苋菜 | NA | Amaranthus spinosus |
| H0792 | Zhang Yu | 章鱼 | Common atlantic octopus | Octopus vulgaris |
| H1094 | Ge Gen | 葛根 | Lobed kudzuvine root | Pueraria lobata |
| H0706 | Yan Hu Suo | 延胡索 | Yanhusuo | Corydalis yanhusuo |
| H1224 | Huai Jiao | 槐角 | pod of japanese pagodatree | Sophora japonica |
| H1066 | Gan Cao | 甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1096 | Ge Hua | 葛花 | flower bud of lobed kudzuvine | Pueraria lobata |
| H0233 | Mao Liang Mian Zhen | 毛两面针 | NA | Zanthoxylum nitidum |
| H1227 | Huai Zhi | 槐枝 | NA | Sophora japonica |
| H0195 | Ma Chi Xian | 马齿苋 | Purslane | Portulaca oleracea |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H1070 | Gan Cao Gan Gao Fen | 甘草干膏粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0872 | Chuan Huang Lian | 川黄连 | rhizome of chinese goldthread | Coptis chinensis |
| H1243 | Huang Lian Xu | 黄连须 | Coptis deltoidea | Coptis chinensis |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0682 | Xiong Huang Lian | 雄黄连 | Coptis deltoidea | Coptis chinensis |
| H0489 | Shui Niu Jiao Nong Suo Fen | 水牛角浓缩粉 | Buffalo horn | Bubalus bubalis |
| H0827 | Zhu Hong Jun | 竹红菌 | Bambusa hypocrella* | Hypocrella bambusae |
| H0488 | Shui Niu Jiao Gan Jin Gao | 水牛角干浸膏 | Buffalo horn | Bubalus bubalis |
| H0214 | Bei He Huan | 北合欢 | Albizia | Albizia julibrissin |
| H0785 | Ze Xi Huang Lian | 择细黄连 | Coptis deltoidea | Coptis chinensis |
| H0651 | Xiang Yuan | 香橼 | Wilson citron | Citrus medica |
| H0006 | Bai Qu Cai | 白屈菜 | Greater celandine | Chelidonium majus |
| H0633 | Xia Tian Wu | 夏天无 | Decumbent corydalis | Corydalis decumbens |
| H0487 | Shui Niu Jiao | 水牛角 | Buffalo horn | Bubalus bubalis |
| H1061 | Bai He | 百合 | Lily | Lilium brownii |