Herb Description

Herb ID:   H0682 Chinese Character:   雄黄连
English Name:  Coptis deltoidea Latin Name:  Coptis chinensis
Chinese Pin Yin :  Xiong Huang Lian TCM-ID:  TCMH2330
Therapeutic Function in Chinese :  NA Therapeutic Function in English:  NA
Herb Function:  NA

Related Targets  (Total: 141)

Target idProtein NameGene SymbolUniprot IDNo.of Literature Evidence
T00CXT Prostaglandin G/H synthase 1PTGS1 P23219
2 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
7 Reference(s)
T08DOL Sulfotransferase 1E1SULT1E1 P49888
1 Reference(s)
T13KGH TyrosinaseTYR P14679
2 Reference(s)
T12PIB Lysosomal alpha-glucosidaseGAA P10253
1 Reference(s)
T83YZD AcetylcholinesteraseACHE P22303
4 Reference(s)
T91T8I Glucose-6-phosphatase catalytic subunit 1G6PC1 P35575
1 Reference(s)
T58J2Y Peroxisome proliferator-activated receptor gammaPPARG P37231
2 Reference(s)
T25Y64 CholinesteraseBCHE P06276
2 Reference(s)
T85AXP Cytochrome P450 3A4CYP3A4 P08684
1 Reference(s)
T02QBS Cytochrome P450 1A2CYP1A2 P05177
1 Reference(s)
T85U8U Caspase-3CASP3 P42574
10 Reference(s)
T88AJI Hypoxia-inducible factor 1-alphaHIF1A Q16665
3 Reference(s)
T92BZ2 Catenin beta-1CTNNB1 P35222
3 Reference(s)
T62P0D Collagenase 3MMP13 P45452
2 Reference(s)
T06RMZ Nuclear factor NF-kappa-B p105 subunitNFKB1 P19838
11 Reference(s)
T91OUC Mucin-5ACMUC5AC P98088
1 Reference(s)
T31U13 Cytochrome P450 2C19CYP2C19 P33261
1 Reference(s)
T22OPB Nuclear factor erythroid 2-related factor 2NFE2L2 Q16236
3 Reference(s)
T81I4T 5'-AMP-activated protein kinase catalytic subunit alpha-1PRKAA1 Q13131
4 Reference(s)
T21DZX Amine oxidase [flavin-containing] AMAOA P21397
3 Reference(s)
T34I45 Neuronal acetylcholine receptor subunit alpha-7CHRNA7 P36544
5 Reference(s)
T22H7B Neuronal acetylcholine receptor subunit alpha-4CHRNA4 P43681
1 Reference(s)
T83P5X Inhibitor of nuclear factor kappa-B kinase subunit betaIKBKB O14920
1 Reference(s)
T74QXI Serine/threonine-protein kinase mTORMTOR P42345
1 Reference(s)
T49ORJ Peroxisome proliferator-activated receptor alphaPPARA Q07869
3 Reference(s)
T70HTD Cytochrome P450 2E1CYP2E1 P05181
1 Reference(s)
T04H8Y Beta-secretase 1BACE1 P56817
1 Reference(s)
T33OSQ Sterol regulatory element-binding protein 1SREBF1 P36956
1 Reference(s)
T26KIE Transcription factor AP-1JUN P05412
3 Reference(s)
T76SUY Solute carrier family 22 member 2SLC22A2 O15244
3 Reference(s)
T43N2D Epidermal growth factor receptorEGFR P00533
3 Reference(s)
T57FUN Beclin-1BECN1 Q14457
1 Reference(s)
T71BDH Mitogen-activated protein kinase 14MAPK14 Q16539
3 Reference(s)
T98RXH Focal adhesion kinase 1PTK2 Q05397
1 Reference(s)
T11ZYR Cytochrome P450 2D6CYP2D6 P10635
1 Reference(s)
T83ENN Solute carrier family 22 member 3SLC22A3 O75751
1 Reference(s)
T09H2Z Nitric oxide synthase, inducibleNOS2 P35228
4 Reference(s)
T25M2J Anoctamin-1ANO1 Q5XXA6
1 Reference(s)
T31MUM 5,6-dihydroxyindole-2-carboxylic acid oxidaseTYRP1 P17643
1 Reference(s)
T20JZ2 Androgen receptorAR P10275
2 Reference(s)
T74QOR Tyrosine-protein kinase JAK3JAK3 P52333
1 Reference(s)
T85C8T Serine/threonine-protein kinase PAK 4PAK4 O96013
1 Reference(s)
T23P74 Caspase-9CASP9 P55211
4 Reference(s)
T50SJ8 5'-AMP-activated protein kinase catalytic subunit alpha-2PRKAA2 P54646
1 Reference(s)
T23TJV Tyrosine 3-monooxygenaseTH P07101
1 Reference(s)
T29MD1 Mitogen-activated protein kinase 8MAPK8 P45983
1 Reference(s)
T44LWL Transcription factor p65RELA Q04206
1 Reference(s)
T54G8J Protein kinase C delta typePRKCD Q05655
1 Reference(s)
T82JWE Cellular tumor antigen p53TP53 P04637
4 Reference(s)
T80OJF Interstitial collagenaseMMP1 P03956
3 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
4 Reference(s)
T75HMM Induced myeloid leukemia cell differentiation protein Mcl-1MCL1 Q07820
1 Reference(s)
T17UP9 C-C motif chemokine 2CCL2 P13500
1 Reference(s)
T32R5L Cyclin-dependent kinase 9CDK9 P50750
1 Reference(s)
T25S8M Phosphatidylethanolamine N-methyltransferasePEMT Q9UBM1
1 Reference(s)
T96OOK Signal transducer and activator of transcription 3STAT3 P40763
1 Reference(s)
T92P67 Vasodilator-stimulated phosphoproteinVASP P50552
2 Reference(s)
T67KTV Transient receptor potential cation channel subfamily V member 1TRPV1 Q8NER1
1 Reference(s)
T45XTW Retinoic acid receptor RXR-alphaRXRA P19793
1 Reference(s)
T52XO3 Cytochrome P450 2J2CYP2J2 P51589
1 Reference(s)
T54SZZ Endoplasmic reticulum chaperone BiPHSPA5 P11021
1 Reference(s)
T06Q1R Amine oxidase [flavin-containing] BMAOB P27338
2 Reference(s)
T69XVX Cytochrome P450 1B1CYP1B1 Q16678
1 Reference(s)
T64UH1 Nitric oxide synthase, endothelialNOS3 P29474
1 Reference(s)
T22H8P Carbonic anhydrase 3CA3 P07451
1 Reference(s)
T38T1U Caspase-8CASP8 Q14790
1 Reference(s)
T80TUC Apoptosis regulator BAXBAX Q07812
7 Reference(s)
T53AOE Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptideTGFB1 P01137
1 Reference(s)
T42EAZ Vascular endothelial growth factor AVEGFA P15692
4 Reference(s)
T74LFK Neurogenic locus notch homolog protein 1NOTCH1 P46531
1 Reference(s)
T62ERY Interleukin-1 receptor-associated kinase 4IRAK4 Q9NWZ3
1 Reference(s)
T22NX4 Toll-like receptor 2TLR2 O60603
1 Reference(s)
T76AZQ Histidine decarboxylaseHDC P19113
1 Reference(s)
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
2 Reference(s)
T82ALJ Glycogen synthase kinase-3 betaGSK3B P49841
2 Reference(s)
T93WZG G1/S-specific cyclin-D1CCND1 P24385
1 Reference(s)
T73HMK Bcl-2-binding component 3, isoforms 1/2BBC3 Q9BXH1
1 Reference(s)
T64W2K Cyclin-dependent kinase inhibitor 1CDKN1A P38936
1 Reference(s)
T33OPP Interleukin-6IL6 P05231
2 Reference(s)
T54CIF Interleukin-8CXCL8 P10145
2 Reference(s)
T04MBA Vascular endothelial growth factor receptor 2KDR P35968
1 Reference(s)
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
2 Reference(s)
T04WT7 FibronectinFN1 P02751
1 Reference(s)
T17CZC Tissue factorF3 P13726
1 Reference(s)
T67UWO C-C motif chemokine 26CCL26 Q9Y258
1 Reference(s)
T49TDM Matrix metalloproteinase-9MMP9 P14780
2 Reference(s)
T02IOG Cyclin-dependent kinase inhibitor 1BCDKN1B P46527
1 Reference(s)
T67LQK Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)MAPK11 Q15759
1 Reference(s)
T23VMI Tumor necrosis factorTNF P01375
2 Reference(s)
T93PLN Serine/threonine-protein kinase/endoribonuclease IRE1ERN1 O75460
1 Reference(s)
T74D4Y CASP8 and FADD-like apoptosis regulatorCFLAR O15519
1 Reference(s)
T50VJF OsteopontinSPP1 P10451
1 Reference(s)
T53KRS E3 ubiquitin-protein ligase NEDD4-likeNEDD4L Q96PU5
1 Reference(s)
T10S5F Cyclin-dependent kinase 4CDK4 P11802
1 Reference(s)
T38G9K TNF receptor-associated factor 2TRAF2 Q12933
1 Reference(s)
T60UPF Parvalbumin alphaPVALB P20472
2 Reference(s)
T69RXK Cytochrome P450 2C9CYP2C9 P11712
1 Reference(s)
T18CUI Neuron-specific calcium-binding protein hippocalcinHPCA P84074
1 Reference(s)
T09BRP NAPKB_RS07820 NA
1 Reference(s)
T39RV3 Dual specificity mitogen-activated protein kinase kinase 1MAP2K1 Q02750
1 Reference(s)
T66S13 Dual specificity mitogen-activated protein kinase kinase 2MAP2K2 P36507
1 Reference(s)
T08SJX Astrocytic phosphoprotein PEA-15PEA15 Q15121
1 Reference(s)
T38OQ4 Peroxiredoxin-2PRDX2 P32119
1 Reference(s)
T38J3Y Gamma-enolaseENO2 P09104
1 Reference(s)
T86ROZ Heme oxygenase 1HMOX1 P09601
1 Reference(s)
T93W1J Vascular endothelial growth factor CVEGFC P49767
1 Reference(s)
T32GWR Ephrin-B2EFNB2 P52799
3 Reference(s)
T95IYZ AdiponectinADIPOQ Q15848
1 Reference(s)
T38H79 Membrane protein MLC1MLC1 Q15049
1 Reference(s)
T62R6K Myosin light chain kinase 3MYLK3 Q32MK0
1 Reference(s)
T45G32 Proto-oncogene tyrosine-protein kinase SrcSRC P12931
1 Reference(s)
T78OTS APC membrane recruitment protein 1AMER1 Q5JTC6
1 Reference(s)
T27LA6 DNADNMT1 P26358
1 Reference(s)
T28HOM LeptinLEP P41159
1 Reference(s)
T38WWN Serum paraoxonase/arylesterase 1PON1 P27169
1 Reference(s)
T28K6X Insulin receptor substrate 1IRS1 P35568
1 Reference(s)
T70VB4 CortistatinCORT O00230
1 Reference(s)
T20E5P Cytochrome b-245 heavy chainCYBB P04839
1 Reference(s)
T09HVO Sodium/hydrogen exchanger 3SLC9A3 P48764
1 Reference(s)
T94H37 Cadherin-1CDH1 P12830
1 Reference(s)
T10ICM Oxidized low-density lipoprotein receptor 1OLR1 P78380
1 Reference(s)
T80XW6 Scavenger receptor class B member 1SCARB1 Q8WTV0
1 Reference(s)
T75PC7 NAMIR21 NA
2 Reference(s)
T38JCD DNA-binding protein inhibitor ID-1ID1 P41134
1 Reference(s)
T58K2N Calmodulin-3;Calmodulin-1;Calmodulin-2CALM3;CALM1;CALM2 P0DP25;P0DP23;P0DP24
1 Reference(s)
T40W2M NAMIR93 NA
1 Reference(s)
T90HSB NAMIR373 NA
1 Reference(s)
T29C6N EzrinEZR P15311
1 Reference(s)
T31P1D Metalloproteinase inhibitor 1TIMP1 P01033
1 Reference(s)
T20H9F Stromelysin-1MMP3 P08254
1 Reference(s)
T67ZT3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENPTEN P60484
2 Reference(s)
T26CFB DNA damage-inducible transcript 3 proteinDDIT3 P35638;P0DPQ6
1 Reference(s)
T33BF9 DNADNMT3B Q9UBC3
1 Reference(s)
T34WFL Proto-oncogene tyrosine-protein kinase receptor RetRET P07949
1 Reference(s)
T25YP8 Aquaporin-4AQP4 P55087
1 Reference(s)
T39M6J ATP-binding cassette sub-family C member 2ABCC2 Q92887
1 Reference(s)
T50WOV ATP-dependent translocase ABCB1ABCB1 P08183
2 Reference(s)
T14ENF Microtubule-associated protein 2MAP2 P11137
1 Reference(s)
T78ZF2 Protein kinase C alpha typePRKCA P17252
1 Reference(s)
T93VFT Endothelin-1EDN1 P05305
1 Reference(s)

Related Compounds  (Total: 18)

Go to browser
C0457
Name: Tricin
Go to browser
C1231
Name: Chlorogenic Acid
Go to browser
C0187
Name: Limonin
Go to browser
C0485
Name: Wogonin
Go to browser
C0073
Name: Ferulic Acid