HIT-result

Target Description

Type	Detail
Target ID	T52XO3
Protein Name	Cytochrome P450 2J2
Uniprot ID	P51589
Protein Name Alias	EC 1.14.14.-; Albendazole monooxygenase (hydroxylating); EC 1.14.14.74; Albendazole monooxygenase (sulfoxide-forming); EC 1.14.14.73; Arachidonic acid epoxygenase; CYPIIJ2; Hydroperoxy icosatetraenoate isomerase; EC 5.4.4.7
Gene ID	1573
Gene Symbol	CYP2J2
Gene Alias	NA
TTD	NA
Pfam	PF00067
GO	0042738:exogenous drug catabolic process 0008405:arachidonic acid 11,12-epoxygenase activity 0016853:isomerase activity 0006690:icosanoid metabolic process 0005506:iron ion binding 0006082:organic acid metabolic process 0006805:xenobiotic metabolic process 0043231:intracellular membrane-bounded organelle 0106301:arachidonic acid 5,6-epoxygenase activity 0005789:endoplasmic reticulum membrane 0008016:regulation of heart contraction 0106255:hydroperoxy icosatetraenoate isomerase activity 0070062:extracellular exosome 0019373:epoxygenase P450 pathway 0043651:linoleic acid metabolic process 0016712:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 0008404:arachidonic acid 14,15-epoxygenase activity 0008395:steroid hydroxylase activity 0006631:fatty acid metabolic process 0008392:arachidonic acid epoxygenase activity 0071614:linoleic acid epoxygenase activity 0020037:heme binding 0005737:cytoplasm
PDB	NA
Drugbank	DB00637 ; DB15305 ; DB00169 ; DB08918 ; DB08931 ; DB09148 ; DB09030 ; DB00342 ; DB06605 ; DB04855 ; DB01118 ; DB04725 ; DB06228
KEGG	hsa:1573

Type

Detail

Target ID

T52XO3

Protein Name

Cytochrome P450 2J2

Uniprot ID

P51589

Protein Name Alias

EC 1.14.14.-; Albendazole monooxygenase (hydroxylating); EC 1.14.14.74; Albendazole monooxygenase (sulfoxide-forming); EC 1.14.14.73; Arachidonic acid epoxygenase; CYPIIJ2; Hydroperoxy icosatetraenoate isomerase; EC 5.4.4.7

Gene ID

1573

Gene Symbol

CYP2J2

Gene Alias

TTD

Pfam

PF00067

0042738:exogenous drug catabolic process

0008405:arachidonic acid 11,12-epoxygenase activity

0016853:isomerase activity

0006690:icosanoid metabolic process

0005506:iron ion binding

0006082:organic acid metabolic process

0006805:xenobiotic metabolic process

0043231:intracellular membrane-bounded organelle

0106301:arachidonic acid 5,6-epoxygenase activity

0005789:endoplasmic reticulum membrane

0008016:regulation of heart contraction

0106255:hydroperoxy icosatetraenoate isomerase activity

0070062:extracellular exosome

0019373:epoxygenase P450 pathway

0043651:linoleic acid metabolic process

0016712:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

0008404:arachidonic acid 14,15-epoxygenase activity

0008395:steroid hydroxylase activity

0006631:fatty acid metabolic process

0008392:arachidonic acid epoxygenase activity

0071614:linoleic acid epoxygenase activity

0020037:heme binding

0005737:cytoplasm

PDB

Drugbank

DB00637 ; DB15305 ; DB00169 ; DB08918 ; DB08931 ; DB09148 ; DB09030 ; DB00342 ; DB06605 ; DB04855 ; DB01118 ; DB04725 ; DB06228

KEGG

hsa:1573

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1228	Huang Bai	黄柏	Amur corktree	Phellodendron amurense
H0029	Jiang Huang Lian	姜黄连	Coptis deltoidea	Coptis chinensis
H1230	Huang Bai Fen	黄柏粉	Amur corktree	Phellodendron amurense
H0673	Xin Jiang Zi Cao	新疆紫草	Arnebia root	Arnebia euchroma
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0872	Chuan Huang Lian	川黄连	rhizome of chinese goldthread	Coptis chinensis
H0082	Jiu Huang Lian	酒黄连	Coptis deltoidea	Coptis chinensis
H1243	Huang Lian Xu	黄连须	Coptis deltoidea	Coptis chinensis
H0682	Xiong Huang Lian	雄黄连	Coptis deltoidea	Coptis chinensis
H1231	Huang Bai Tan	黄柏炭	Amur corktree	Phellodendron amurense
H1242	Huang Lian Gan Jin Gao	黄连干浸膏	Coptis deltoidea	Coptis chinensis
H0844	Zi Cao	紫草	Redroot gromwell	Lithospermum erythrorhizon
H0827	Zhu Hong Jun	竹红菌	Bambusa hypocrella*	Hypocrella bambusae
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0706	Yan Hu Suo	延胡索	Yanhusuo	Corydalis yanhusuo
H0704	Yan Guan Huang Bai	盐关黄柏	Amur cork tree	Phellodendron amurense
H1241	Huang Lian	黄连	Coptis deltoidea	Coptis chinensis
H0785	Ze Xi Huang Lian	择细黄连	Coptis deltoidea	Coptis chinensis
H1115	Guan Huang Bai	关黄柏	Amur cork tree	Phellodendron amurense
H0651	Xiang Yuan	香橼	Wilson citron	Citrus medica
H0760	Yu Huang Lian	萸黄连	Coptis deltoidea	Coptis chinensis
H0006	Bai Qu Cai	白屈菜	Greater celandine	Chelidonium majus
H0633	Xia Tian Wu	夏天无	Decumbent corydalis	Corydalis decumbens
H0231	Mao Gao Cai	茅膏菜	Lunate peltate sundew	Drosera peltata var. lunata
H1068	Bai He Liu Jin Gao	百合流浸膏	Lily	Lilium brownii
H1061	Bai He	百合	Lily	Lilium brownii
H0652	Xiang Yuan Pi	香橼皮	Wilson citron	Citrus medica
H0252	Mian Da Ji	绵大戟	NA	Euphorbia pekinensis

Target Description

Related Compounds (Total: 4)

Related Herbs (Total: 28)