Herb Description
| Herb ID: H0006 | Chinese Character: 白屈菜 |
| English Name: Greater celandine | Latin Name: Chelidonium majus |
| Chinese Pin Yin : Bai Qu Cai | TCM-ID: TCMH101 |
| Therapeutic Function in Chinese : NA | Therapeutic Function in English: NA |
| Herb Function: NA | |
Related Targets (Total: 203)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T05WWN | Corticoliberin | CRH |
P06850 |
1 Reference(s) |
| T76KYI | Trace amine-associated receptor 1 | TAAR1 |
Q96RJ0 |
1 Reference(s) |
| T01E7W | Aurora kinase B | AURKB |
Q96GD4 |
1 Reference(s) |
| T01IGB | Serine/threonine-protein kinase/endoribonuclease IRE2 | ERN2 |
Q76MJ5 |
1 Reference(s) |
| T34I45 | Neuronal acetylcholine receptor subunit alpha-7 | CHRNA7 |
P36544 |
7 Reference(s) |
| T22H7B | Neuronal acetylcholine receptor subunit alpha-4 | CHRNA4 |
P43681 |
2 Reference(s) |
| T38N54 | Fumarate hydratase, mitochondrial | FH |
P07954 |
1 Reference(s) |
| T18VDI | Apoptosis-inducing factor 1, mitochondrial | AIFM1 |
O95831 |
1 Reference(s) |
| T62KUY | Endonuclease G, mitochondrial | ENDOG |
Q14249 |
1 Reference(s) |
| T90ADC | BH3-interacting domain death agonist | BID |
P55957 |
1 Reference(s) |
| T83P5X | Inhibitor of nuclear factor kappa-B kinase subunit beta | IKBKB |
O14920 |
1 Reference(s) |
| T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
8 Reference(s) |
| T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
2 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
3 Reference(s) |
| T70HTD | Cytochrome P450 2E1 | CYP2E1 |
P05181 |
1 Reference(s) |
| T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
3 Reference(s) |
| T33OSQ | Sterol regulatory element-binding protein 1 | SREBF1 |
P36956 |
1 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
2 Reference(s) |
| T76SUY | Solute carrier family 22 member 2 | SLC22A2 |
O15244 |
2 Reference(s) |
| T43N2D | Epidermal growth factor receptor | EGFR |
P00533 |
2 Reference(s) |
| T57FUN | Beclin-1 | BECN1 |
Q14457 |
1 Reference(s) |
| T71BDH | Mitogen-activated protein kinase 14 | MAPK14 |
Q16539 |
5 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
8 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
5 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
5 Reference(s) |
| T98RXH | Focal adhesion kinase 1 | PTK2 |
Q05397 |
1 Reference(s) |
| T11ZYR | Cytochrome P450 2D6 | CYP2D6 |
P10635 |
2 Reference(s) |
| T83ENN | Solute carrier family 22 member 3 | SLC22A3 |
O75751 |
2 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
2 Reference(s) |
| T45NNT | Serine/threonine-protein kinase MRCK alpha | CDC42BPA |
Q5VT25 |
1 Reference(s) |
| T85JAT | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | SDHB |
P21912 |
1 Reference(s) |
| T17E95 | Protein kinase C gamma type | PRKCG |
P05129 |
1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
3 Reference(s) |
| T66GX9 | Proline-rich transmembrane protein 2 | PRRT2 |
Q7Z6L0 |
8 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
5 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
11 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
3 Reference(s) |
| T99GD2 | Hepatocyte growth factor-like protein | MST1 |
P26927 |
2 Reference(s) |
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
3 Reference(s) |
| T92FAW | Dual specificity protein phosphatase 1 | DUSP1 |
P28562 |
6 Reference(s) |
| T02P7Q | Dihydrofolate reductase | DHFR |
P00374 |
2 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
5 Reference(s) |
| T25Y64 | Cholinesterase | BCHE |
P06276 |
2 Reference(s) |
| T13KGH | Tyrosinase | TYR |
P14679 |
1 Reference(s) |
| T58XLK | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 |
P18031 |
2 Reference(s) |
| T26EZU | Myc proto-oncogene protein | MYC |
P01106 |
2 Reference(s) |
| T56TXY | Polyunsaturated fatty acid 5-lipoxygenase | ALOX5 |
P09917 |
2 Reference(s) |
| T31U13 | Cytochrome P450 2C19 | CYP2C19 |
P33261 |
1 Reference(s) |
| T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
2 Reference(s) |
| T11BI7 | Toll-like receptor 4 | TLR4 |
O00206 |
1 Reference(s) |
| T09BRP | NA | PKB_RS07820 |
NA |
2 Reference(s) |
| T85AXP | Cytochrome P450 3A4 | CYP3A4 |
P08684 |
1 Reference(s) |
| T54X6V | Intermediate conductance calcium-activated potassium channel protein 4 | KCNN4 |
O15554 |
1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
7 Reference(s) |
| T14DX3 | Ribosomal protein S6 kinase alpha-3 | RPS6KA3 |
P51812 |
2 Reference(s) |
| T77TY2 | Protein disulfide-isomerase | P4HB |
P07237 |
2 Reference(s) |
| T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
3 Reference(s) |
| T30VNV | Myeloperoxidase | MPO |
P05164 |
2 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
7 Reference(s) |
| T83DDX | Endothelial protein C receptor | PROCR |
Q9UNN8 |
1 Reference(s) |
| T06VX0 | MAP/microtubule affinity-regulating kinase 4 | MARK4 |
Q96L34 |
1 Reference(s) |
| T24C0P | Bile acid receptor | NR1H4 |
Q96RI1 |
4 Reference(s) |
| T20RA0 | Adenosine deaminase | ADA |
P00813 |
1 Reference(s) |
| T93SFQ | NAD-dependent protein deacetylase sirtuin-1 | SIRT1 |
Q96EB6 |
1 Reference(s) |
| T74P7I | G-protein coupled bile acid receptor 1 | GPBAR1 |
Q8TDU6 |
1 Reference(s) |
| T27M4K | Rho GTPase-activating protein 7 | DLC1 |
Q96QB1 |
1 Reference(s) |
| T80PUR | Caspase-7 | CASP7 |
P55210 |
1 Reference(s) |
| T38T1U | Caspase-8 | CASP8 |
Q14790 |
2 Reference(s) |
| T64LKA | Bile salt export pump | ABCB11 |
O95342 |
1 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
1 Reference(s) |
| T67CB6 | Transcriptional regulator ERG | ERG |
P11308 |
1 Reference(s) |
| T70U24 | Sigma non-opioid intracellular receptor 1 | SIGMAR1 |
Q99720 |
1 Reference(s) |
| T25S8M | Phosphatidylethanolamine N-methyltransferase | PEMT |
Q9UBM1 |
2 Reference(s) |
| T44IGL | Switch-associated protein 70 | SWAP70 |
Q9UH65 |
2 Reference(s) |
| T12SOF | Eukaryotic initiation factor 4A-I | EIF4A1 |
P60842 |
1 Reference(s) |
| T88AHJ | Histamine H3 receptor | HRH3 |
Q9Y5N1 |
2 Reference(s) |
| T90BQW | Sodium channel protein type 11 subunit alpha | SCN11A |
Q9UI33 |
1 Reference(s) |
| T67KTV | Transient receptor potential cation channel subfamily V member 1 | TRPV1 |
Q8NER1 |
4 Reference(s) |
| T38OH4 | Caspase-1 | CASP1 |
P29466 |
1 Reference(s) |
| T68XO1 | Indoleamine 2,3-dioxygenase 1 | IDO1 |
P14902 |
2 Reference(s) |
| T14V9R | Dihydroorotate dehydrogenase | DHODH |
Q02127 |
1 Reference(s) |
| T85RZS | Corticotropin-releasing factor receptor 1 | CRHR1 |
P34998 |
1 Reference(s) |
| T56NC7 | Beta-defensin 4A | DEFB4A; DEFB4B |
O15263 |
1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
4 Reference(s) |
| T07NML | P-selectin | SELP |
P16109 |
2 Reference(s) |
| T14FV1 | Cadherin-5 | CDH5 |
P33151 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
6 Reference(s) |
| T06N1B | Histamine H1 receptor | HRH1 |
P35367 |
3 Reference(s) |
| T32UNL | Lens fiber major intrinsic protein | MIP |
P30301 |
1 Reference(s) |
| T92P67 | Vasodilator-stimulated phosphoprotein | VASP |
P50552 |
2 Reference(s) |
| T45XTW | Retinoic acid receptor RXR-alpha | RXRA |
P19793 |
1 Reference(s) |
| T52XO3 | Cytochrome P450 2J2 | CYP2J2 |
P51589 |
1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
2 Reference(s) |
| T54SZZ | Endoplasmic reticulum chaperone BiP | HSPA5 |
P11021 |
1 Reference(s) |
| T25H22 | Protein kinase C beta type | PRKCB |
P05771 |
2 Reference(s) |
| T87UKX | Glucose-6-phosphate 1-dehydrogenase | G6PD |
P11413 |
1 Reference(s) |
| T17B47 | Excitatory amino acid transporter 4 | SLC1A6 |
P48664 |
1 Reference(s) |
| T09HVO | Sodium/hydrogen exchanger 3 | SLC9A3 |
P48764 |
2 Reference(s) |
| T23NFE | C-type natriuretic peptide | NPPC |
P23582 |
1 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
2 Reference(s) |
| T45B9P | ATP-sensitive inward rectifier potassium channel 11 | KCNJ11 |
Q14654 |
1 Reference(s) |
| T84ONF | High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor | FCAMR |
Q8WWV6 |
1 Reference(s) |
| T88E8M | Carbonic anhydrase 9 | CA9 |
Q16790 |
1 Reference(s) |
| T25L2V | Growth-regulated alpha protein | CXCL1 |
P09341 |
1 Reference(s) |
| T76F14 | DNA mismatch repair protein Msh2 | MSH2 |
P43246 |
1 Reference(s) |
| T01L5I | DNA mismatch repair protein Msh6 | MSH6 |
P52701 |
1 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
3 Reference(s) |
| T17FIA | Angiotensinogen | AGT |
P01019 |
1 Reference(s) |
| T93VFT | Endothelin-1 | EDN1 |
P05305 |
1 Reference(s) |
| T33R9C | NA | TRNG |
NA |
1 Reference(s) |
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
1 Reference(s) |
| T00CXT | Prostaglandin G/H synthase 1 | PTGS1 |
P23219 |
1 Reference(s) |
| T99XQ3 | DNA topoisomerase 1 | TOP1 |
P11387 |
1 Reference(s) |
| T68BGR | Glial fibrillary acidic protein | GFAP |
P14136 |
1 Reference(s) |
| T46YMA | Ras-related C3 botulinum toxin substrate 1 | RAC1 |
P63000 |
1 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
2 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
5 Reference(s) |
| T93R42 | Dipeptidyl peptidase 1 | CTSC |
P53634 |
1 Reference(s) |
| T89L4V | Insulin | INS |
P01308 |
1 Reference(s) |
| T21Q0D | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR |
P04035 |
1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
4 Reference(s) |
| T16A2X | Catalase | CAT |
P04040 |
1 Reference(s) |
| T29MD1 | Mitogen-activated protein kinase 8 | MAPK8 |
P45983 |
1 Reference(s) |
| T94K7H | Cytochrome P450 7A1 | CYP7A1 |
P22680 |
1 Reference(s) |
| T76AZQ | Histidine decarboxylase | HDC |
P19113 |
2 Reference(s) |
| T93W1J | Vascular endothelial growth factor C | VEGFC |
P49767 |
2 Reference(s) |
| T20JZ2 | Androgen receptor | AR |
P10275 |
1 Reference(s) |
| T32GWR | Ephrin-B2 | EFNB2 |
P52799 |
3 Reference(s) |
| T95IYZ | Adiponectin | ADIPOQ |
Q15848 |
1 Reference(s) |
| T38H79 | Membrane protein MLC1 | MLC1 |
Q15049 |
1 Reference(s) |
| T62R6K | Myosin light chain kinase 3 | MYLK3 |
Q32MK0 |
1 Reference(s) |
| T45G32 | Proto-oncogene tyrosine-protein kinase Src | SRC |
P12931 |
1 Reference(s) |
| T80OJF | Interstitial collagenase | MMP1 |
P03956 |
2 Reference(s) |
| T78OTS | APC membrane recruitment protein 1 | AMER1 |
Q5JTC6 |
1 Reference(s) |
| T27LA6 | DNA | DNMT1 |
P26358 |
1 Reference(s) |
| T28HOM | Leptin | LEP |
P41159 |
1 Reference(s) |
| T38WWN | Serum paraoxonase/arylesterase 1 | PON1 |
P27169 |
1 Reference(s) |
| T28K6X | Insulin receptor substrate 1 | IRS1 |
P35568 |
1 Reference(s) |
| T70VB4 | Cortistatin | CORT |
O00230 |
1 Reference(s) |
| T20E5P | Cytochrome b-245 heavy chain | CYBB |
P04839 |
1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
1 Reference(s) |
| T94H37 | Cadherin-1 | CDH1 |
P12830 |
1 Reference(s) |
| T10ICM | Oxidized low-density lipoprotein receptor 1 | OLR1 |
P78380 |
1 Reference(s) |
| T80XW6 | Scavenger receptor class B member 1 | SCARB1 |
Q8WTV0 |
1 Reference(s) |
| T75PC7 | NA | MIR21 |
NA |
2 Reference(s) |
| T38JCD | DNA-binding protein inhibitor ID-1 | ID1 |
P41134 |
1 Reference(s) |
| T58K2N | Calmodulin-3;Calmodulin-1;Calmodulin-2 | CALM3;CALM1;CALM2 |
P0DP25;P0DP23;P0DP24 |
1 Reference(s) |
| T40W2M | NA | MIR93 |
NA |
1 Reference(s) |
| T90HSB | NA | MIR373 |
NA |
1 Reference(s) |
| T29C6N | Ezrin | EZR |
P15311 |
1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
2 Reference(s) |
| T31P1D | Metalloproteinase inhibitor 1 | TIMP1 |
P01033 |
2 Reference(s) |
| T20H9F | Stromelysin-1 | MMP3 |
P08254 |
1 Reference(s) |
| T62P0D | Collagenase 3 | MMP13 |
P45452 |
1 Reference(s) |
| T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
2 Reference(s) |
| T26CFB | DNA damage-inducible transcript 3 protein | DDIT3 |
P35638;P0DPQ6 |
1 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
1 Reference(s) |
| T33BF9 | DNA | DNMT3B |
Q9UBC3 |
1 Reference(s) |
| T34WFL | Proto-oncogene tyrosine-protein kinase receptor Ret | RET |
P07949 |
1 Reference(s) |
| T25YP8 | Aquaporin-4 | AQP4 |
P55087 |
1 Reference(s) |
| T74SS7 | Glutamate receptor ionotropic, NMDA 2A | GRIN2A |
Q12879 |
1 Reference(s) |
| T54G8J | Protein kinase C delta type | PRKCD |
Q05655 |
1 Reference(s) |
| T68NCI | Aldo-keto reductase family 1 member B1 | AKR1B1 |
P15121 |
1 Reference(s) |
| T32JN2 | Beta-glucuronidase | GUSB |
P08236 |
1 Reference(s) |
| T33KFW | Matrilysin | MMP7 |
P09237 |
2 Reference(s) |
| T60UPF | Parvalbumin alpha | PVALB |
P20472 |
2 Reference(s) |
| T69RXK | Cytochrome P450 2C9 | CYP2C9 |
P11712 |
2 Reference(s) |
| T18CUI | Neuron-specific calcium-binding protein hippocalcin | HPCA |
P84074 |
1 Reference(s) |
| T54CIF | Interleukin-8 | CXCL8 |
P10145 |
1 Reference(s) |
| T39RV3 | Dual specificity mitogen-activated protein kinase kinase 1 | MAP2K1 |
Q02750 |
1 Reference(s) |
| T66S13 | Dual specificity mitogen-activated protein kinase kinase 2 | MAP2K2 |
P36507 |
1 Reference(s) |
| T08SJX | Astrocytic phosphoprotein PEA-15 | PEA15 |
Q15121 |
1 Reference(s) |
| T38OQ4 | Peroxiredoxin-2 | PRDX2 |
P32119 |
1 Reference(s) |
| T38J3Y | Gamma-enolase | ENO2 |
P09104 |
1 Reference(s) |
| T82I7J | C-C motif chemokine 16 | CCL16 |
O15467 |
1 Reference(s) |
| T87QUW | Actin, aortic smooth muscle | ACTA2 |
P62736 |
1 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
2 Reference(s) |
| T04WT7 | Fibronectin | FN1 |
P02751 |
1 Reference(s) |
| T57HGP | Tumor necrosis factor receptor superfamily member 6 | FAS |
P25445 |
1 Reference(s) |
| T39M6J | ATP-binding cassette sub-family C member 2 | ABCC2 |
Q92887 |
1 Reference(s) |
| T71BV3 | Glutathione peroxidase 1 | GPX1 |
P07203 |
1 Reference(s) |
| T68VY3 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | DDAH1 |
O94760 |
1 Reference(s) |
| T91X8E | Sterol carrier protein 2 | SCP2 |
P22307 |
1 Reference(s) |
| T44ISH | Transcription factor MafG | MAFG |
O15525 |
1 Reference(s) |
| T97FEF | Broad substrate specificity ATP-binding cassette transporter ABCG2 | ABCG2 |
Q9UNQ0 |
1 Reference(s) |
| T75B9S | Cyclic AMP-responsive element-binding protein 1 | CREB1 |
P16220 |
1 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
1 Reference(s) |
| T84FV7 | Zinc finger protein SNAI2 | SNAI2 |
O43623 |
1 Reference(s) |
| T91OUC | Mucin-5AC | MUC5AC |
P98088 |
1 Reference(s) |
| T31SX8 | Bone morphogenetic protein 2 | BMP2 |
P12643 |
1 Reference(s) |
| T02RA6 | Protein disulfide-isomerase A6 | PDIA6 |
Q15084 |
1 Reference(s) |
| T03G09 | Tumor necrosis factor ligand superfamily member 11 | TNFSF11 |
O14788 |
1 Reference(s) |
| T49NJW | C-C motif chemokine 20 | CCL20 |
P78556 |
1 Reference(s) |
| T60WNX | Vasopressin-neurophysin 2-copeptin | AVP |
P01185 |
1 Reference(s) |
| T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
1 Reference(s) |
| T00W4R | B1 bradykinin receptor | BDKRB1 |
P46663 |
1 Reference(s) |
| T88ER9 | Serine/threonine-protein kinase D1 | PRKD1 |
Q15139 |
1 Reference(s) |
| T30AEN | Aquaporin-5 | AQP5 |
P55064 |
1 Reference(s) |
| T06Q1R | Amine oxidase [flavin-containing] B | MAOB |
P27338 |
1 Reference(s) |
| T57L0X | Oxysterols receptor LXR-alpha | NR1H3 |
Q13133 |
1 Reference(s) |
| T34Y8V | Oxysterols receptor LXR-beta | NR1H2 |
P55055 |
1 Reference(s) |
| T24LXT | G2/mitotic-specific cyclin-B1 | CCNB1 |
P14635 |
1 Reference(s) |
| T94JI0 | Tubulin alpha-1A chain | TUBA1A |
Q71U36 |
1 Reference(s) |
Related Compounds (Total: 27)
C0125
Name: Histamine
C0466
Name: Tyramine
C0078
Name: Flavonol
C0291
Name: Paraben
C1236
Name: Choline
key description of the interaction between compound and target