Target Description

Type Detail
Target ID T46YMA
Protein Name Ras-related C3 botulinum toxin substrate 1
Uniprot ID P63000
Protein Name Alias EC 3.6.5.2;  Cell migration-inducing gene 5 protein;  Ras-like protein TC25;  p21-Rac1
Gene ID 5879
Gene Symbol RAC1
Gene Alias TC25
TTD T88752: Research target
Pfam PF00071
GO
0007596:blood coagulation

0008045:motor neuron axon guidance

0008360:regulation of cell shape

0001934:positive regulation of protein phosphorylation

0060263:regulation of respiratory burst

0016020:membrane

0051496:positive regulation of stress fiber assembly

1902622:regulation of neutrophil migration

0030865:cortical cytoskeleton organization

0043652:engulfment of apoptotic cell

0034446:substrate adhesion-dependent cell spreading

0070062:extracellular exosome

0044877:protein-containing complex binding

0003376:sphingosine-1-phosphate receptor signaling pathway

0038096:Fc-gamma receptor signaling pathway involved in phagocytosis

0002551:mast cell chemotaxis

0000139:Golgi membrane

0003924:GTPase activity

0051117:ATPase binding

0009653:anatomical structure morphogenesis

0051897:positive regulation of protein kinase B signaling

0007155:cell adhesion

0051894:positive regulation of focal adhesion assembly

0019901:protein kinase binding

0005737:cytoplasm

0071526:semaphorin-plexin signaling pathway

0048013:ephrin receptor signaling pathway

0005829:cytosol

0042826:histone deacetylase binding

0042995:cell projection

0098978:glutamatergic synapse

0050690:regulation of defense response to virus by virus

0051492:regulation of stress fiber assembly

0048012:hepatocyte growth factor receptor signaling pathway

0031996:thioesterase binding

0035556:intracellular signal transduction

0036464:cytoplasmic ribonucleoprotein granule

0007015:actin filament organization

0005525:GTP binding

0048870:cell motility

0043312:neutrophil degranulation

0005925:focal adhesion

0038095:Fc-epsilon receptor signaling pathway

0007163:establishment or maintenance of cell polarity

0043197:dendritic spine

0030334:regulation of cell migration

0031343:positive regulation of cell killing

0005886:plasma membrane

0031116:positive regulation of microtubule polymerization

0071260:cellular response to mechanical stimulus

0042470:melanosome

0101003:ficolin-1-rich granule membrane

0055038:recycling endosome membrane

0006954:inflammatory response

0043231:intracellular membrane-bounded organelle

0030031:cell projection assembly

0005856:cytoskeleton

0032956:regulation of actin cytoskeleton organization

0097178:ruffle assembly

0032707:negative regulation of interleukin-23 production

0051022:Rho GDP-dissociation inhibitor binding

0045428:regulation of nitric oxide biosynthetic process

0010592:positive regulation of lamellipodium assembly

0030036:actin cytoskeleton organization

0031410:cytoplasmic vesicle

0005802:trans-Golgi network

0030027:lamellipodium

0016601:Rac protein signal transduction

0048261:negative regulation of receptor-mediated endocytosis

0010595:positive regulation of endothelial cell migration

0001764:neuron migration

0048010:vascular endothelial growth factor receptor signaling pathway

0045453:bone resorption

0030667:secretory granule membrane

0032587:ruffle membrane

0005938:cell cortex

0035025:positive regulation of Rho protein signal transduction

0030032:lamellipodium assembly

0031295:T cell costimulation

0098794:postsynapse

0009611:response to wounding

0051668:localization within membrane

0031529:ruffle organization

0019899:enzyme binding

0030041:actin filament polymerization

1900026:positive regulation of substrate adhesion-dependent cell spreading

0005789:endoplasmic reticulum membrane

0007160:cell-matrix adhesion

0051056:regulation of small GTPase mediated signal transduction

0010310:regulation of hydrogen peroxide metabolic process

0008361:regulation of cell size

0035774:positive regulation of insulin secretion involved in cellular response to glucose stimulus

0060071:Wnt signaling pathway, planar cell polarity pathway

0031234:extrinsic component of cytoplasmic side of plasma membrane

0010764:negative regulation of fibroblast migration

0008283:cell population proliferation

0045740:positive regulation of DNA replication

0010811:positive regulation of cell-substrate adhesion

0090023:positive regulation of neutrophil chemotaxis

0010591:regulation of lamellipodium assembly

PDB 1MH1 ; 6BC1 ; 6X1G ; 1RYF ; 1HE1 ; 1FOE ; 5HZH ; 3SBE ; 5QQH ; 5QQI ; 3SU8 ; 2H7V ; 5QQE ; 6TGC ; 2NZ8 ; 2WKR ; 5N6O ; 5QQD ; 2WKQ ; 3RYT ; 5O33 ; 4YON ; 2FJU ; 1HH4 ; 4GZL ; 6AGP ; 4GZM ; 2WKP ; 2RMK ; 3SUA ; 2VRW ; 2YIN ; 2P2L ; 1I4T ; 3SBD ; 5QQF ; 1RYH ; 3BJI ; 5FI0 ; 1I4D ; 5QQG ; 5QQK ; 3TH5 ; 5QU9 ; 1G4U ; 3B13 ; 5QQM ; 5QQJ ; 7AJK ; 5QQL ; 1E96 ; 5QQN ; 1I4L
Drugbank DB00993 ; DB04315 ; DB00514
KEGG hsa:5879

Related Compounds  (Total: 6)

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C0280
Name: Oxytocin
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C0305
Name: Phorbol Myristate Acetate
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C0369
Name: Rhein
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C0473
Name: Uridine Triphosphate
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C1203
Name: Caffeic Acid


Related Herbs  (Total: 201)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H0648 Xiang Si Teng相思藤 Coralhead plant vineAbrus precatorius
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0509 Cang Er苍耳 Siberian cockleburXanthium sibiricum
H0698 Ya Zao牙皂 Chinese honeylocust abnormal fruitGleditsia sinensis
H0680 Xiong Dan熊胆 Bear gallConyza blinii
H0779 Zao Jiao Zhen皂角针 Chinese honeylocust spineGleditsia sinensis
H1090 Gao Ben藁本 Chinese ligusticumLigusticum sinense
H0043 Jie Zi芥子 India mustard seedBrassica juncea
H1061 Bai He百合 LilyLilium brownii
H0357 Ren Shen人参 GinsengPanax ginseng
H0818 Zhi Zi栀子 Cape jasmine fruitGardenia jasminoides
H0074 Jing Jie Tan荆芥炭 NASchizonepetae herba
H1102 Gu Sui Bu骨碎补 Fortune’s drynaria rhizomeDrynaria fortunei
H0639 Xiang Cha Cai香茶菜 Common rabdosiaIsodon amethystoides
H0854 Zi Wei Gen Pi紫葳根皮 NACampsis grandiflora
H0424 Shan Zhi山栀 Cape jasmineGardenia jasminoides
H1019 E Bu Shi Cao鹅不食草 Small centipedaCentipeda minima
H0239 Bei Sha Shen北沙参 Coastal glehniaGlehnia littoralis
H0878 Ba Dou Shuang巴豆霜 Defatted croton seed powderCroton tiglium
H0776 Zao Ci皂刺 spine of chinese honeylocustSpina gleditsiae
H0302 Ou Fen藕粉 Hindu lotus large rhizomeNelumbo nucifera
H0115 Kuan Dong Hua款冬花 Common coltsfootTussilago farfara
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H0585 Tu Yin Chen Hao土茵陈蒿 Capillary wormwoodArtemisia capillaris
H0016 Ji Xue Cao积雪草 Asiatic pennywortCentella asiatica
H0242 Bei Sha Shen Liu Jin Gao北沙参流浸膏 Glehnia littoralisGlehnia littoralis
H0897 Chuan Lian川楝 ChinaberryMelia azedarach
H0227 Mang Guo Ye芒果叶 Mango leafMangifera indica
H0965 Deng Zhan Xi Xin灯盏细辛 Shortscape fleabaneErigeron breviscapus
H0122 La Jiao Jin Gao辣椒浸膏 Bush redpepperCapsicum frutescens
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H0083 Jiu Jie Cha九节茶 Glabrous sarcandraSarcandra glabra
H0570 Tu Fu Ling土茯苓 Glabrous greenbrierSmilax glabra
H1068 Bai He Liu Jin Gao百合流浸膏 LilyLilium brownii
H0817 Zhi Zhu Xiang蜘蛛香 Jatamans valerianaValeriana jatamansii
H1055 Bai Guo Ren白果仁 ginkgoGinkgo biloba
H0123 La Jiao Liu Jin Gao辣椒流浸膏 Bush redpepperCapsicum frutescens
H0956 Dang Gui Gan Jin Gao当归干浸膏 NAAngelica sinensis
H0746 Yin Chen Hao Gan Jin Gao茵陈蒿干浸膏 Capillary wormwoodArtemisia capillaris
H0185 Luo Shi Teng络石藤 Chinese star jasmineTrachelospermum jasminoides
H0275 Mu Zei木贼 Common scouring rushEquisetum hiemale
H1124 Guang Jin Qian Cao广金钱草 Snowbellleaf tickcloverDesmodium styracifolium
H0462 Shi Liu石榴 Pomegranate fruitPunica granatum
H1167 He Tao核桃 English walnut seedSemen juglandis
H1244 Huang Miao黄苗 NATaraxacum mongolicum
H1034 Fei Yang Cao飞杨草 NAEuphorbia hirta
H0387 San Ya Ku三桠苦 Common rueRuta graveolens
H0391 Sang Pi桑皮 Prepared root-bark white mulberryMorus alba
H0998 Dong Gua Pi冬瓜皮 Chinese waxgourd peelBenincasa hispida
H0540 Tian Ji Huang田基黄 all - grass of japanese st. johnswortGrangea maderaspatana
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H0219 Man Shan Hong满山红 Dahurian rhododendronRhododendron dauricum
H1133 Gui Jian Yu鬼箭羽 Winged euonymusEuonymus alatus
H0396 Sang Ye桑叶 White mulberry leafMorus alba
H0423 Shan Zha Ye山楂叶 NACrataegi folium
H0418 Shan Yin Chen山茵陈 Capillary wormwoodArtemisia capillaris
H0045 Jin Fei Cao金沸草 Japanese inulaInula japonica
H0887 Chuan Xin Lian Gan Jin Gao穿心莲干浸膏 Common andrographisAndrographis paniculata
H0691 Xue Lian Hua雪莲花 Snow lotusSaussurea involucrata
H0109 Ku Lian Zi苦楝子 NAMelia azedarach
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0327 Qian Li Guang千里光 Climbing groundselSenecio scandens
H0436 Bo He薄荷 Wild mintMentha haplocalyx
H0289 Niu Bang Zi牛蒡子 Great burdock fruitArctium lappa
H0181 Luo Bu Ma罗布麻 DogbaneApocynum venetum
H0951 Dan Shen Jin Gao丹参浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0472 Shu Da Huang熟大黄 NARheum palmatum
H1188 Hong Hua红花 SafflowerCarthamus tinctorius
H0075 Jing Mi粳米 RiceOryza sativa
H1097 Gong Ding Xiang公丁香 NASyzygium aromaticum
H0574 Cao Dou Kou草豆蔻 Katsumada galangalAlpinia katsumadai
H1166 He Shou Wu何首乌 Tuber fleeceflowerPolygonum multiflorum
H1100 Gu Jing Cao谷精草 PipewartEriocaulon buergerianum
H0243 Mi Kuan Dong Hua蜜款冬花 Common coltsfootTussilago farfara
H1235 Huang Hao黄蒿 Virg ate wormwoodArtemisia scoparia
H0566 Cao Cong Rong草苁蓉 Russian boschniakiaBoschniakia rossica
H0463 Shi Liu Pi石榴皮 Pomegranate peelPunica granatum
H0141 Lian Zi Xin莲子心 Hindu lotus plumuleNelumbo nucifera
H0576 Tu Mu Xiang土木香 Elecampane inulaInula helenium
H1201 Hu Er Cao虎耳草 Creeping rockfoilSaxifraga stolonifera
H1221 Hua Xiang Shu Guo Xu化香树果序 NAPlatycarya strobilacea
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0515 Suan Shi Liu酸石榴 PomegranatePunica granatum
H0750 Yin Xing Ye银杏叶 Folium ginkgoGinkgo biloba
H1213 Hu Zhang虎杖 Japanese fleeceflowerPolygonum cuspidatum
H0484 Shui Fei Ji水飞蓟 St marysSilybum marianum
H1195 Bai Ma Gu白马骨 all - grass of snow of june.Herba serissae
H0304 Ou Pian藕片 Hindu lotus large rhizomeNelumbo nucifera
H0871 Chuan Duan川断 TeaselsDipsacus asper
H0954 Dan Zhu Ye淡竹叶 Common lophatherumLophatherum gracile
H0100 Juan Bai卷柏 Tamariskoid spikemossSelaginella tamariscina
H0147 Lie Dang列当 Skyblue broomrapeOrobanche coerulescens
H0427 Shan Zhu Yu山茱萸 Asiatic cornelian cherryCornus officinalis
H0365 Rou Dou Kou肉豆蔻 Common nutmegMyristica fragrans
H0047 Jin Gang Teng金刚藤 NAGymnema sylvestre
H0140 Lian Zi莲子 Hindu lotus seedNelumbo nucifera
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0889 Chuan Xin Lian Jin Gao穿心莲浸膏 Common andrographisAndrographis paniculata
H0949 Dan Shen丹参 The root of red-rooted salviaSalvia miltiorrhiza
H0932 Ba Qia菝葜 Chinaroot greenbrierSmilax china
H1186 Hong Gen Cao红根草 Hispid sageSalvia prionitis
H0614 Wu Zhao Long五爪龙 Cairo morninggloryIpomoea cairica
H0094 Gou Qi枸杞 Chinese wolfberry fruitLycium chinense
H0778 Zao Jiao Ci皂角刺 spine of chinese honeylocustSpina gleditsiae
H0237 Mei Gui Hua玫瑰花 Rugose rose flowerRosa rugosa
H0765 Chi Dou赤豆 Assuki beanVigna angularis
H0892 Chuan Xiong川芎 cnidium officinaleCnidium officinale
H1016 Du Zhong Tan杜仲炭 EucommiaEucommia ulmoides
H0440 Sheng Di Hong Jing Tian圣地红景天 Integripetal rhodiolaRhodiola sacra
H0601 Wu Mei乌梅 Japanese apricotPrunus mume
H0354 Ren Dong Teng忍冬藤 Japanese honeysuckle vineLonicera japonica
H0050 Jin Gang Tou金刚头 NAGymnema sylvestre
H0534 Teng Li Gen藤梨根 NAActinidia arguta
H0448 Bo He You薄荷油 MintMentha haplocalyx
H0248 Mi Ying Su Ke蜜罂粟壳 Opium poppyPapaver somniferum
H0926 Da Huang大黄 Medicinal rhubarbRheum officinale
H0819 Zhi Zi Jin Gao栀子浸膏 Cape jasmine fruitGardenia jasminoides
H1017 Du Zhong Ye杜仲叶 Eucommia leafEucommia ulmoides
H1183 Hong Dou红豆 Hosie ormosiaOrmosia hosiei
H0085 Jiu Yu Rou酒萸肉 Asiatic cornelian cherryCornus officinalis
H0745 Yin Chen Hao茵陈蒿 Capillary wormwoodArtemisia capillaris
H0612 Cao Shan Hu Jin Gao草珊瑚浸膏 NASarcandra glabra
H1051 Bai Guo白果 Ginkgo nutGinkgo biloba
H0093 Ju Pi橘皮 Tangerine pericarpCitrus reticulata
H0681 Xiong Dan Fen熊胆粉 Bear gallConyza blinii
H0464 Shi Liu Zi石榴子 NAPunica granatum
H0108 Ku Lian Pi苦楝皮 Chinaberry-tree barkMelia azedarach
H0757 Ying Su Ke罂粟壳 Opium poppy pericarpPapaver somniferum
H0729 Ye Ju Hua野菊花 Indian wild chrysanthemum flowerChrysanthemum indicum
H0891 Chuan Xin Lian Ye穿心莲叶 Powder of green chiretta leavesAndrographis herba
H1240 Huang Jing Zi黄荆子 NAVitex negundo
H0102 Jue Ming Zi决明子 Sickle senna seedCassia tora
H0632 Xia Ku Cao夏枯草 Common selfhealPrunella vulgaris
H0119 La Jiao辣椒 Bush redpepperCapsicum frutescens
H0990 Ding Xiang丁香 Clove treeSyzygium aromaticum
H0314 Pu Gong Ying蒲公英 Mongolian dandelionTaraxacum mongolicum
H0121 La Jiao Jin Chu Ye辣椒浸出液 Bush redpepperCapsicum frutescens
H0315 Pu Gong Ying Jin Gao蒲公英浸膏 Mongolian dandelionTaraxacum mongolicum
H0116 Kuan Ye Xie Cao宽叶缬草 NAValeriana officinalis
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H1217 Bai Mei Hua白梅花 Japanese apricot flowerPrunus mume
H0869 Ba Dou巴豆 Pu rging crotonCroton tiglium
H0886 Chuan Xin Lian穿心莲 Common andrographisAndrographis paniculata
H0095 Gou Qi Zi枸杞子 Chinese wolfberry fruitLycium chinense
H0697 Ya Ma Zi亚麻子 Common flax seedLinum usitatissimum
H0888 Ba Dou Ye巴豆叶 Pu rging crotonCroton tiglium
H1000 Dong Gua Zi冬瓜子 Chinese waxgourd seedBenincasa hispida
H0927 Da Huang Jin Gao大黄浸膏 Medicinal rhubarbRheum officinale
H0166 Long Kui龙葵 Black nightshadeSolanum nigrum
H0950 Dan Shen Gan Jin Gao丹参干浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H1099 Gou Teng钩藤 Sharpleaf gambirplantUncaria rhynchophylla
H1015 Du Zhong杜仲 EucommiaEucommia ulmoides
H0546 Tian Shan Xue Lian Hua天山雪莲花 NASaussurea involucrata
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin
H1020 E Bu Shi Cao Nong Suo Ye鹅不食草浓缩液 Small centipedaCentipeda minima
H0777 Zao Jia皂荚 Chinese honeylocustGleditsia sinensis
H0379 Bian Xu萹蓄 Common knotgrassPolygonum aviculare
H1152 Bai Jie Zi白芥子 White mustard seedSinapis alba
H0006 Bai Qu Cai白屈菜 Greater celandineChelidonium majus
H0088 Ju He橘核 Tangerine seedCitrus reticulata
H0685 Xuan Cao Gen萱草根 Orange daylilyHemerocallis fulva
H0772 Yue Ji Hua月季花 Chinese roseRosa chinensis
H0700 Ya Zhi Cao鸭跖草 Common dayflowerCommelina communis
H1168 He Tao Ren核桃仁 English walnut seedSemen juglandis
H0938 Da Suan大蒜 GarlicAllium sativum
H0496 Shui Ze Lan水泽兰 NALycopus lucidus
H0447 Sheng Ma升麻 BugbaneCimicifuga foetida
H0894 Chuan Xu Duan川续断 Himalayan teaselDipsacus asperoides
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H0764 Yu Xing Cao鱼腥草 Heartleaf houttuyniaHouttuynia cordata
H0139 Lian Qiao连翘 Weeping forsythiaForsythia suspensa
H0195 Ma Chi Xian马齿苋 PurslanePortulaca oleracea
H0741 Yi Zhi Hao一枝蒿 Alpine yarrow herbSolidago decurrens
H1164 He Geng荷梗 Hindu lotus petioleNelumbo nucifera
H0397 Sang Zhi桑枝 White mulberry branchMorus alba
H0839 Zhua Di Hu抓地虎 ValerianValeriana officinalis
H0890 Chuan Xin Lian Nong Suo Ye穿心莲浓缩液 Common andrographisAndrographis paniculata
H0301 Ou Hindu lotus large rhizomeNelumbo nucifera
H0941 Da Zao大枣 Chinese dateZiziphus jujuba
H0774 Yun Xiang Jin Gao芸香浸膏 RutaRuta graveolens
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0602 Wu Mei Rou乌梅肉 EbonyPrunus mume
H0928 Da Huang Liu Jin Gao大黄流浸膏 Medicinal rhubarbRheum officinale
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0844 Zi Cao紫草 Redroot gromwellLithospermum erythrorhizon
H0582 Cao Dou Kou Ren草豆蔻仁 Katsumada galangalAlpinia katsumadai
H0893 Chuan Xiong Jin Gao川芎浸膏 cnidium officinaleCnidium officinale
H0671 Xie Cao缬草 Common valerianaValeriana officinalis
H0514 Cang Er Cao苍耳草 Cocklebur grassXanthium sibiricum
H1169 He Ye荷叶 Hindu lotus leafNelumbo nucifera
H1011 Bai Chou白丑 Pharbitis seedSemen pharbitidis
H1220 Hua Xiang Shu Guo化香树果 NAPlatycarya strobilacea
H0690 Xue Lian雪莲 Snow lotusSaussurea involucrata
H0416 Shan Shen山参 NAPanax ginseng
H0649 Xiang Si Zi相思子 Coralhead plantAbrus precatorius
H1173 Hei Chou黑丑 Pharbitis seedSemen pharbitidis
H0756 Ying Su罂粟 Opium poppyPapaver somniferum
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H0955 Dang Gui当归 Chinese angelicaAngelica sinensis
H0241 Mi Hou Tao猕猴桃 Yangtao actinidiaActinidia chinensis