Herb Description
| Herb ID: H0540 | Chinese Character: 田基黄 |
| English Name: all - grass of japanese st. johnswort | Latin Name: Grangea maderaspatana |
| Chinese Pin Yin : Tian Ji Huang | TCM-ID: TCMH2087 |
| Therapeutic Function in Chinese : NA | Therapeutic Function in English: NA |
| Herb Function: NA | |
Related Targets (Total: 117)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T97UTI | 6-phosphogluconate dehydrogenase, decarboxylating | PGD |
P52209 |
2 Reference(s) |
| T30VNV | Myeloperoxidase | MPO |
P05164 |
1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
7 Reference(s) |
| T83DDX | Endothelial protein C receptor | PROCR |
Q9UNN8 |
1 Reference(s) |
| T06VX0 | MAP/microtubule affinity-regulating kinase 4 | MARK4 |
Q96L34 |
2 Reference(s) |
| T24C0P | Bile acid receptor | NR1H4 |
Q96RI1 |
1 Reference(s) |
| T77TY2 | Protein disulfide-isomerase | P4HB |
P07237 |
1 Reference(s) |
| T20RA0 | Adenosine deaminase | ADA |
P00813 |
1 Reference(s) |
| T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
1 Reference(s) |
| T93SFQ | NAD-dependent protein deacetylase sirtuin-1 | SIRT1 |
Q96EB6 |
2 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
2 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
6 Reference(s) |
| T80GUN | 72 kDa type IV collagenase | MMP2 |
P08253 |
1 Reference(s) |
| T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
2 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
3 Reference(s) |
| T54G8J | Protein kinase C delta type | PRKCD |
Q05655 |
2 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
1 Reference(s) |
| T20IHC | Diacylglycerol O-acyltransferase 1 | DGAT1 |
O75907 |
1 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
1 Reference(s) |
| T16UZ4 | Dipeptidyl peptidase 4 | DPP4 |
P27487 |
1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
4 Reference(s) |
| T13Z69 | Solute carrier family 22 member 6 | SLC22A6 |
Q4U2R8 |
1 Reference(s) |
| T50PQ4 | Solute carrier family 22 member 8 | SLC22A8 |
Q8TCC7 |
1 Reference(s) |
| T26CFB | DNA damage-inducible transcript 3 protein | DDIT3 |
P35638;P0DPQ6 |
2 Reference(s) |
| T55L5P | Macrophage scavenger receptor types I and II | MSR1 |
P21757 |
1 Reference(s) |
| T08U92 | Mitochondrial brown fat uncoupling protein 1 | UCP1 |
P25874 |
1 Reference(s) |
| T43N2D | Epidermal growth factor receptor | EGFR |
P00533 |
1 Reference(s) |
| T46YMA | Ras-related C3 botulinum toxin substrate 1 | RAC1 |
P63000 |
1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
3 Reference(s) |
| T64UWL | Taste receptor type 2 member 39 | TAS2R39 |
P59534 |
1 Reference(s) |
| T71BDH | Mitogen-activated protein kinase 14 | MAPK14 |
Q16539 |
2 Reference(s) |
| T76PKX | Mast/stem cell growth factor receptor Kit | KIT |
P10721 |
1 Reference(s) |
| T40DIM | Corticosteroid 11-beta-dehydrogenase isozyme 1 | HSD11B1 |
P28845 |
1 Reference(s) |
| T54VET | Protein tyrosine phosphatase type IVA 3 | PTP4A3 |
O75365 |
1 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
3 Reference(s) |
| T37ADS | Early growth response protein 1 | EGR1 |
P18146 |
1 Reference(s) |
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
3 Reference(s) |
| T20JZ2 | Androgen receptor | AR |
P10275 |
1 Reference(s) |
| T12RJE | Casein kinase II subunit alpha' | CSNK2A2 |
P19784 |
1 Reference(s) |
| T47C6A | Phosphoglycerate mutase 1 | PGAM1 |
P18669 |
1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
1 Reference(s) |
| T89L4V | Insulin | INS |
P01308 |
1 Reference(s) |
| T21Q0D | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR |
P04035 |
1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
2 Reference(s) |
| T16A2X | Catalase | CAT |
P04040 |
2 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
4 Reference(s) |
| T29MD1 | Mitogen-activated protein kinase 8 | MAPK8 |
P45983 |
1 Reference(s) |
| T02GD4 | Tumor necrosis factor ligand superfamily member 6 | FASLG |
P48023 |
3 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
4 Reference(s) |
| T97KL5 | Microsomal glutathione S-transferase 1 | MGST1 |
P10620 |
2 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
2 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
1 Reference(s) |
| T81BH5 | Sulfotransferase 1A1 | SULT1A1 |
P50225 |
2 Reference(s) |
| T32SPJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | PIK3CG |
P48736 |
1 Reference(s) |
| T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
1 Reference(s) |
| T09KQF | Proliferating cell nuclear antigen | PCNA |
P12004 |
1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
| T26EZU | Myc proto-oncogene protein | MYC |
P01106 |
2 Reference(s) |
| T24LXT | G2/mitotic-specific cyclin-B1 | CCNB1 |
P14635 |
1 Reference(s) |
| T07TMB | Cyclin-dependent kinase 1 | CDK1 |
P06493 |
1 Reference(s) |
| T74JJN | Fatty acid synthase | FASN |
P49327 |
1 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
2 Reference(s) |
| T76QBQ | CREB-regulated transcription coactivator 2 | CRTC2 |
Q53ET0 |
1 Reference(s) |
| T13KGH | Tyrosinase | TYR |
P14679 |
1 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
1 Reference(s) |
| T96DNP | Nucleic acid dioxygenase ALKBH1 | ALKBH1 |
Q13686 |
1 Reference(s) |
| T13HYI | Alpha-ketoglutarate-dependent dioxygenase FTO | FTO |
Q9C0B1 |
1 Reference(s) |
| T36YWU | Kelch-like ECH-associated protein 1 | KEAP1 |
Q14145 |
1 Reference(s) |
| T58FWN | Tyrosine-protein kinase BTK | BTK |
Q06187 |
1 Reference(s) |
| T06Q1R | Amine oxidase [flavin-containing] B | MAOB |
P27338 |
1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
2 Reference(s) |
| T01QLH | Estrogen receptor | ESR1 |
P03372 |
2 Reference(s) |
| T80OJF | Interstitial collagenase | MMP1 |
P03956 |
1 Reference(s) |
| T27U96 | Granulocyte-macrophage colony-stimulating factor | CSF2 |
P04141 |
1 Reference(s) |
| T84WE9 | Vascular endothelial growth factor receptor 1 | FLT1 |
P17948 |
1 Reference(s) |
| T04MBA | Vascular endothelial growth factor receptor 2 | KDR |
P35968 |
1 Reference(s) |
| T29JZ3 | Vascular endothelial growth factor receptor 3 | FLT4 |
P35916 |
1 Reference(s) |
| T47H3O | Heat shock protein HSP 90-alpha | HSP90AA1 |
P07900 |
1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
1 Reference(s) |
| T54B00 | P2X purinoceptor 7 | P2RX7 |
Q99572 |
1 Reference(s) |
| T87QUW | Actin, aortic smooth muscle | ACTA2 |
P62736 |
1 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
3 Reference(s) |
| T04WT7 | Fibronectin | FN1 |
P02751 |
1 Reference(s) |
| T57HGP | Tumor necrosis factor receptor superfamily member 6 | FAS |
P25445 |
1 Reference(s) |
| T08B2M | M-phase inducer phosphatase 1 | CDC25A |
P30304 |
1 Reference(s) |
| T33UEM | Lactoperoxidase | LPO |
P22079 |
1 Reference(s) |
| T03TJ0 | Interleukin-33 | IL33 |
O95760 |
1 Reference(s) |
| T40G6B | Prostaglandin reductase 1 | PTGR1 |
Q14914 |
1 Reference(s) |
| T31VDH | Myeloid differentiation primary response protein MyD88 | MYD88 |
Q99836 |
1 Reference(s) |
| T86UXL | Cyclin-A2 | CCNA2 |
P20248 |
1 Reference(s) |
| T64W2K | Cyclin-dependent kinase inhibitor 1 | CDKN1A |
P38936 |
1 Reference(s) |
| T62Y4H | Protein kinase C epsilon type | PRKCE |
Q02156 |
1 Reference(s) |
| T75EH8 | Glucagon-like peptide 1 receptor | GLP1R |
P43220 |
1 Reference(s) |
| T91UNL | Keratin, type I cytoskeletal 14 | KRT14 |
P02533 |
1 Reference(s) |
| T11BI7 | Toll-like receptor 4 | TLR4 |
O00206 |
2 Reference(s) |
| T28K6X | Insulin receptor substrate 1 | IRS1 |
P35568 |
1 Reference(s) |
| T52CKD | Pro-epidermal growth factor | EGF |
P01133 |
1 Reference(s) |
| T42PUG | Solute carrier family 2, facilitated glucose transporter member 1 | SLC2A1 |
P11166 |
1 Reference(s) |
| T68SE0 | Solute carrier family 2, facilitated glucose transporter member 4 | SLC2A4 |
P14672 |
1 Reference(s) |
| T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
1 Reference(s) |
| T95K0K | Interferon alpha-1/13 | IFNA1; IFNA13 |
P01562 |
1 Reference(s) |
| T64LKA | Bile salt export pump | ABCB11 |
O95342 |
2 Reference(s) |
| T78O6C | Mothers against decapentaplegic homolog 3 | SMAD3 |
P84022 |
1 Reference(s) |
| T84CEG | Claudin-5 | CLDN5 |
O00501 |
1 Reference(s) |
| T30AEN | Aquaporin-5 | AQP5 |
P55064 |
1 Reference(s) |
| T47RAK | NA | MIR145 |
NA |
1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
1 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
1 Reference(s) |
| T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
1 Reference(s) |
| T75NEV | Aquaporin-1 | AQP1 |
P29972 |
1 Reference(s) |
| T54SZZ | Endoplasmic reticulum chaperone BiP | HSPA5 |
P11021 |
1 Reference(s) |
| T37SV3 | Occludin | OCLN |
Q16625 |
1 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
1 Reference(s) |
| T69F5W | Forkhead box protein D3 | FOXD3 |
Q9UJU5 |
1 Reference(s) |
| T13I7C | Transforming growth factor beta-2 proprotein | TGFB2 |
P61812 |
1 Reference(s) |
| T44EUX | Fragile X mental retardation syndrome-related protein 1 | FXR1 |
P51114 |
1 Reference(s) |
| T92LK2 | Tumor necrosis factor ligand superfamily member 10 | TNFSF10 |
P50591 |
1 Reference(s) |
Related Compounds (Total: 8)
C1240
Name: Chrysophanol
C0306
Name: Physcion
C0377
Name: Rutin
C0090
Name: Gallic Acid
C0881
Name: Aloe-Emodin
key description of the interaction between compound and target