Target Description

Type Detail
Target ID T27U96
Protein Name Granulocyte-macrophage colony-stimulating factor
Uniprot ID P04141
Protein Name Alias GM-CSF;  Colony-stimulating factor;  CSF;  Molgramostin;  Sargramostim
Gene ID 1437
Gene Symbol CSF2
Gene Alias GMCSF
TTD T74002: Successful target
Pfam PF01109
GO
0097011:cellular response to granulocyte macrophage colony-stimulating factor stimulus

0042116:macrophage activation

0019221:cytokine-mediated signaling pathway

0045637:regulation of myeloid cell differentiation

0005129:granulocyte macrophage colony-stimulating factor receptor binding

0030099:myeloid cell differentiation

0045892:negative regulation of transcription, DNA-templated

0008083:growth factor activity

0034405:response to fluid shear stress

0043231:intracellular membrane-bounded organelle

0034021:response to silicon dioxide

0010628:positive regulation of gene expression

0005615:extracellular space

0005125:cytokine activity

0030224:monocyte differentiation

0005576:extracellular region

0001892:embryonic placenta development

0000165:MAPK cascade

0010744:positive regulation of macrophage derived foam cell differentiation

0001821:histamine secretion

0071222:cellular response to lipopolysaccharide

0030225:macrophage differentiation

2001240:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

0006955:immune response

0071803:positive regulation of podosome assembly

0042045:epithelial fluid transport

0008284:positive regulation of cell population proliferation

0097028:dendritic cell differentiation

0043011:myeloid dendritic cell differentiation

0030223:neutrophil differentiation

0042531:positive regulation of tyrosine phosphorylation of STAT protein

0045187:regulation of circadian sleep/wake cycle, sleep

0032747:positive regulation of interleukin-23 production

PDB 1CSG ; 4NKQ ; 5C7X ; 6BFQ ; 5D70 ; 5D72 ; 4RS1 ; 6BFS ; 5D71 ; 2GMF
Drugbank DB05194
KEGG hsa:1437

Related Compounds  (Total: 7)

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C0041
Name: Emodin
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C0163
Name: Juglone
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C0366
Name: Retinol
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C0456
Name: Tretinoin
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C0476
Name: Ursolic Acid


Related Herbs  (Total: 220)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0809 Zhi Mu知母 Common anemarrhenaAnemarrhena asphodeloides
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H1127 Guang Shan Zha广山楂 Chinese hawthornCrataegus pinnatifida
H0308 Pi Ba Ren枇杷仁 NAEriobotrya japonica
H0698 Ya Zao牙皂 Chinese honeylocust abnormal fruitGleditsia sinensis
H0613 Wu Yue Ai五月艾 ArtemisiaArtemisia princeps
H1026 Fan Hun Cao返魂草 Tatarian asterAster tataricus
H0779 Zao Jiao Zhen皂角针 Chinese honeylocust spineGleditsia sinensis
H0853 Zi Wan紫菀 Tatarion asterAster tataricus
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0043 Jie Zi芥子 India mustard seedBrassica juncea
H1061 Bai He百合 LilyLilium brownii
H0002 Hui Xiang茴香 Fennel fruitFoeniculum vulgare
H0818 Zhi Zi栀子 Cape jasmine fruitGardenia jasminoides
H1223 Huai Hun Cao还魂草 NAAster tataricus
H0074 Jing Jie Tan荆芥炭 NASchizonepetae herba
H1102 Gu Sui Bu骨碎补 Fortune’s drynaria rhizomeDrynaria fortunei
H0854 Zi Wei Gen Pi紫葳根皮 NACampsis grandiflora
H1109 Bai Hua She She Cao白花蛇舌草 Spreading hedyitisOldenlandia diffusa
H0419 Shan Zha山楂 Chinese hawthornCrataegus pinnatifida
H0424 Shan Zhi山栀 Cape jasmineGardenia jasminoides
H1072 Gan Cao Gao甘草膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0860 Zong Lv Zi棕榈子 NATrachycarpus fortunei
H1049 Feng Xiang Zhi Chou Gao枫香脂稠膏 NALiquidambar formosana
H0302 Ou Fen藕粉 Hindu lotus large rhizomeNelumbo nucifera
H0585 Tu Yin Chen Hao土茵陈蒿 Capillary wormwoodArtemisia capillaris
H0177 Lu Lu Tong路路通 Beautiful sweetgumLiquidambar formosana
H0154 Ai Ye You艾叶油 Argy wormwood leafArtemisia argyi
H0637 Cha Ye茶叶 Common teaCamellia sinensis
H1075 Gan Cao Liu Jin Gao甘草流浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0063 Jin Ye Zi金叶子 Yunnan craibiodendronCraibiodendron yunnanese
H0016 Ji Xue Cao积雪草 Asiatic pennywortCentella asiatica
H0989 Ding Kui Cao丁葵草 Herb of twinleaf zorniaKummerowia striata
H0967 Di Er Cao地耳草 Japanese stJohn’swortHypericum japonicum
H1073 Gan Cao Jie甘草节 Glycyrrhiza uralensis fischGlycyrrhiza uralensis
H0250 Mi Zi Wan蜜紫菀 Tatarian asterAster tataricus
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H1047 Feng Xiang Ye枫香叶 NALiquidambar formosana
H0570 Tu Fu Ling土茯苓 Glabrous greenbrierSmilax glabra
H0857 Zong Ban Tan棕板炭 NATrachycarpus fortunei
H1068 Bai He Liu Jin Gao百合流浸膏 LilyLilium brownii
H0298 Niu Xi Xi牛西西 Patience dockRumex patientia
H1138 Bai Jiang Cao败酱草 All - grass of dahurian patriniaThlaspi arvense
H0902 Chun Pi椿皮 Ailanthus bark, tree of heaven barkAilanthi cortex
H0462 Shi Liu石榴 Pomegranate fruitPunica granatum
H0746 Yin Chen Hao Gan Jin Gao茵陈蒿干浸膏 Capillary wormwoodArtemisia capillaris
H0224 Man Tuo Luo Ye曼陀罗叶 Hindu datura leafDatura metel
H1053 Fu Ling茯苓 Indian breadWolfiporia cocos
H1167 He Tao核桃 English walnut seedSemen juglandis
H1036 Fen Dan Pi粉丹皮 Tree peony barkPaeonia suffruticosa
H1034 Fei Yang Cao飞杨草 NAEuphorbia hirta
H1029 Fang Er Cha方儿茶 khair in hindiSenegalia catechu
H0391 Sang Pi桑皮 Prepared root-bark white mulberryMorus alba
H0300 Nv Zhen Zi女贞子 Glossy privet fruitLigustrum lucidum
H0998 Dong Gua Pi冬瓜皮 Chinese waxgourd peelBenincasa hispida
H0638 Xiang Bei象贝 FritillariaFritillaria thunbergii
H0540 Tian Ji Huang田基黄 all - grass of japanese st. johnswortGrangea maderaspatana
H0925 Da Fu Zi大腹子 Areca palmAreca catechu
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H0591 Wei Ling Cai委陵菜 Chinese cinquefoilPotentilla chinensis
H1133 Gui Jian Yu鬼箭羽 Winged euonymusEuonymus alatus
H0470 Shi Ye柿叶 Persimmon leafDiospyros kaki
H0693 Xue Xie血蝎 Dragon's bloodDaemonorops draco
H0396 Sang Ye桑叶 White mulberry leafMorus alba
H0418 Shan Yin Chen山茵陈 Capillary wormwoodArtemisia capillaris
H0423 Shan Zha Ye山楂叶 NACrataegi folium
H0855 Chuan Bei Mu川贝母 Fritillaria unibracteataFritillaria cirrhosa
H1070 Gan Cao Gan Gao Fen甘草干膏粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0216 Man Jing Ye蔓荆叶 Threeleaf chastetree leafVitex trifolia
H0747 An Xi Xiang安息香 Sumatra snowbelStyrax benzoin
H0856 Zong Ban棕板 NATrachycarpus fortunei
H0327 Qian Li Guang千里光 Climbing groundselSenecio scandens
H0420 Shan Zha Chou Gao山楂稠膏 Chinese hawthornCrataegus pinnatifida
H0289 Niu Bang Zi牛蒡子 Great burdock fruitArctium lappa
H0069 Jin Ying Zi Ti Qu Ye金樱子提取液 Cherokee rose seedRosa laevigata
H0181 Luo Bu Ma罗布麻 DogbaneApocynum venetum
H0951 Dan Shen Jin Gao丹参浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0472 Shu Da Huang熟大黄 NARheum palmatum
H0646 Xiang Qing Lan香青兰 DragonheadDracocephalum moldavica
H0110 Ku Mu苦木 Indian quassiawoodPicrasma quassioides
H1097 Gong Ding Xiang公丁香 NASyzygium aromaticum
H0229 Mao Da Ding Cao毛大丁草 Pilose gerberaGerbera piloselloides
H0226 Man Yue Mei蔓越莓 CranberryVaccinium oxycoccos
H0493 Shui Yang Mei水杨梅 Japanese avensGeum japonicum
H0574 Cao Dou Kou草豆蔻 Katsumada galangalAlpinia katsumadai
H0450 Shi Chang Pu石菖蒲 Grassleaved sweetflagAcorus tatarinowii
H0979 Di Yu地榆 Garden burnetSanguisorba officinalis
H1166 He Shou Wu何首乌 Tuber fleeceflowerPolygonum multiflorum
H0331 Qiang Huo羌活 Incised notopterygiumNotopterygium incisum
H1100 Gu Jing Cao谷精草 PipewartEriocaulon buergerianum
H0253 Mian Hua Gen棉花根 Levant cotton rootGossypium herbaceum
H1235 Huang Hao黄蒿 Virg ate wormwoodArtemisia scoparia
H0060 Jin Si Ku Lian金丝苦楝 NACardiospermum halicacabum
H0701 Yan Bai岩柏 NAJuniperus formosana
H0963 Dao Kou Cao倒扣草 NAAchyranthes aspera
H0939 Da Xue Teng大血藤 SargentgloryvineSargentodoxa cuneata
H0463 Shi Liu Pi石榴皮 Pomegranate peelPunica granatum
H0141 Lian Zi Xin莲子心 Hindu lotus plumuleNelumbo nucifera
H1067 Gan Cao Fen甘草粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0689 Xue Feng Teng血风藤 NAVentilago leiocarpa
H1221 Hua Xiang Shu Guo Xu化香树果序 NAPlatycarya strobilacea
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0515 Suan Shi Liu酸石榴 PomegranatePunica granatum
H0519 Suo Yang锁阳 Songaria cynomoriumCynomorium songaricum
H1213 Hu Zhang虎杖 Japanese fleeceflowerPolygonum cuspidatum
H0193 Ma Bian Cao马鞭草 European verbenaVerbena officinalis
H0304 Ou Pian藕片 Hindu lotus large rhizomeNelumbo nucifera
H0067 Jin Ying Zi金樱子 Cherokee rose seedRosa laevigata
H0871 Chuan Duan川断 TeaselsDipsacus asper
H0485 Shui Hong Hua水红花 Fructus polygoni orientalisPolygonum orientale
H0427 Shan Zhu Yu山茱萸 Asiatic cornelian cherryCornus officinalis
H0365 Rou Dou Kou肉豆蔻 Common nutmegMyristica fragrans
H0152 Ling Zhi Jin Gao灵芝浸膏 NAGanoderma lucidum
H0140 Lian Zi莲子 Hindu lotus seedNelumbo nucifera
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0949 Dan Shen丹参 The root of red-rooted salviaSalvia miltiorrhiza
H0422 Shan Zha Tan山楂炭 Chinese hawthornCrataegus pinnatifida
H0562 Tou Gu Cao透骨草 Tuberculate speranskiaSperanskia tuberculata
H1186 Hong Gen Cao红根草 Hispid sageSalvia prionitis
H0614 Wu Zhao Long五爪龙 Cairo morninggloryIpomoea cairica
H0486 Shui Hong Hua Ye水红花叶 Fructus polygoni orientalisPolygonum orientale
H0932 Ba Qia菝葜 Chinaroot greenbrierSmilax china
H1203 Hu Ji Sheng槲寄生 Colored mistletoeViscum coloratum
H0656 Xiao Bo Gen小檗根 Barberry rootBerberis julianae
H0715 Che Qian Zi车前子 seed of asiatic pantainPlantago asiatica
H0237 Mei Gui Hua玫瑰花 Rugose rose flowerRosa rugosa
H0765 Chi Dou赤豆 Assuki beanVigna angularis
H0020 Ji Yan Cao鸡眼草 Striate kummerowiaKummerowia striata
H1016 Du Zhong Tan杜仲炭 EucommiaEucommia ulmoides
H0601 Wu Mei乌梅 Japanese apricotPrunus mume
H0354 Ren Dong Teng忍冬藤 Japanese honeysuckle vineLonicera japonica
H1074 Gan Cao Jin Gao甘草浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1214 Hua Jiao花椒 Bunge pricklyashZanthoxylum bungeanum
H0926 Da Huang大黄 Medicinal rhubarbRheum officinale
H1184 Bai Lian白蔹 Japanese ampelopsisAmpelopsis japonica
H0720 Yang Jin Hua洋金花 Hindu datura flowerDatura metel
H1183 Hong Dou红豆 Hosie ormosiaOrmosia hosiei
H0085 Jiu Yu Rou酒萸肉 Asiatic cornelian cherryCornus officinalis
H1017 Du Zhong Ye杜仲叶 Eucommia leafEucommia ulmoides
H0745 Yin Chen Hao茵陈蒿 Capillary wormwoodArtemisia capillaris
H0819 Zhi Zi Jin Gao栀子浸膏 Cape jasmine fruitGardenia jasminoides
H1137 Gui Yuan桂圆 NADimocarpus longan
H1069 Gan Cao Gan Gao甘草干膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0464 Shi Liu Zi石榴子 NAPunica granatum
H1240 Huang Jing Zi黄荆子 NAVitex negundo
H0102 Jue Ming Zi决明子 Sickle senna seedCassia tora
H0632 Xia Ku Cao夏枯草 Common selfhealPrunella vulgaris
H0990 Ding Xiang丁香 Clove treeSyzygium aromaticum
H0503 Song Jie松节 Knotty pine wood, pine nodular branchLignum pini nodi
H0361 Ren Zi Cao人字草 Herb of twinleaf zorniaKummerowia striata
H1217 Bai Mei Hua白梅花 Japanese apricot flowerPrunus mume
H0859 Chuan Bei Mu Liu Jin Gao川贝母流浸膏 Fritillaria unibracteataFritillaria cirrhosa
H0858 Zong Lv Pi棕榈皮 Fortune windmillpalmTrachycarpus fortunei
H0421 Shan Zha Qing Gao山楂清膏 Chinese hawthornCrataegus pinnatifida
H1000 Dong Gua Zi冬瓜子 Chinese waxgourd seedBenincasa hispida
H0927 Da Huang Jin Gao大黄浸膏 Medicinal rhubarbRheum officinale
H0453 Shi Di柿蒂 Persimmon persistent calyxDiospyros kaki
H0494 Shui Yang Mei Gen水杨梅根 Japanese avens rootGeum japonicum
H0103 Ai Ye艾叶 Argy wormwood leafArtemisia argyi
H0801 Chong Bai La虫白蜡 Cera chinensis waxEricerus pela
H0950 Dan Shen Gan Jin Gao丹参干浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0166 Long Kui龙葵 Black nightshadeSolanum nigrum
H1099 Gou Teng钩藤 Sharpleaf gambirplantUncaria rhynchophylla
H1015 Du Zhong杜仲 EucommiaEucommia ulmoides
H0240 Mi Gan Cao蜜甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0777 Zao Jia皂荚 Chinese honeylocustGleditsia sinensis
H1066 Gan Cao甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0225 Man Tuo Luo Zi曼陀罗子 Hindu datura seedDatura metel
H0169 Lou Lu漏芦 Uniflower swisscentauryRhaponticum uniflorum
H1152 Bai Jie Zi白芥子 White mustard seedSinapis alba
H0087 Ju Gu Ye枸骨叶 FOLIUM iLICIS cORNUTAEIlex cornuta
H0217 Man Jing Zi蔓荆子 Threeleaf chastetree fruitVitex trifolia
H0733 Ye Shan Zha野山楂 nippon bawthornCrataegus pinnatifida
H0408 Bing Lang槟榔 BetenutpalmAreca catechu
H0072 Jing Jie荆芥 Fineleaf schizonepetaSchizonepeta tenuifolia
H1198 Hou Tou Jun猴头菌 Bearded tooth carpophoreHericium erinaceus
H1168 He Tao Ren核桃仁 English walnut seedSemen juglandis
H0496 Shui Ze Lan水泽兰 NALycopus lucidus
H0577 Tu Niu Xi土牛膝 Common achyranthesAchyranthes aspera
H0894 Chuan Xu Duan川续断 Himalayan teaselDipsacus asperoides
H0068 Jin Ying Zi Rou金樱子肉 Cherokee rose seedRosa laevigata
H1004 Bai Cha白茶 White teaCamellia sinensis
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H0764 Yu Xing Cao鱼腥草 Heartleaf houttuyniaHouttuynia cordata
H0139 Lian Qiao连翘 Weeping forsythiaForsythia suspensa
H0195 Ma Chi Xian马齿苋 PurslanePortulaca oleracea
H1164 He Geng荷梗 Hindu lotus petioleNelumbo nucifera
H1211 Bai Mei白眉 pilose gerbera herbGerbera piloselloides
H0397 Sang Zhi桑枝 White mulberry branchMorus alba
H0881 Chuan Qiang Huo川羌活 Incised notopterygiumNotopterygium incisum
H0301 Ou Hindu lotus large rhizomeNelumbo nucifera
H0444 Sheng Gan Cao生甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0153 Ling Zhi(1)灵芝 Lucid ganodermaGanoderma lucidum
H0941 Da Zao大枣 Chinese dateZiziphus jujuba
H0073 Jing Jie Sui荆芥穗 NASchizonepetae spica
H0773 Chi Fu Ling赤茯苓 light red indian breadWolfiporia cocos
H0053 Jin Lian Hua金莲花 Chinese globeflowerTrollius chinensis
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0602 Wu Mei Rou乌梅肉 EbonyPrunus mume
H0928 Da Huang Liu Jin Gao大黄流浸膏 Medicinal rhubarbRheum officinale
H0622 Xi He Liu西河柳 Chinese tamarisk twigCacumen tamaricis
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0844 Zi Cao紫草 Redroot gromwellLithospermum erythrorhizon
H0158 Liu Ling Ju六棱菊 NALaggera alata
H1128 Bai Jiang败酱 Whiteflower patriniaPatrinia villosa
H0582 Cao Dou Kou Ren草豆蔻仁 Katsumada galangalAlpinia katsumadai
H0451 Shi Chang Pu Jin Gao石菖蒲浸膏 Grassleaved sweetflagAcorus tatarinowii
H0565 Tu Bie Chong土鳖虫 CockroachEupolyphaga sinensis
H0452 Shi Chang Pu Qing Gao石菖蒲清膏 Grassleaved sweetflagAcorus tatarinowii
H0320 Qi Shu Gen漆树根 true lacquertree rootToxicodendron succedaneum
H1169 He Ye荷叶 Hindu lotus leafNelumbo nucifera
H1011 Bai Chou白丑 Pharbitis seedSemen pharbitidis
H1220 Hua Xiang Shu Guo化香树果 NAPlatycarya strobilacea
H0056 Jin Qiao Mai金荞麦 Wild buckwheat rhizomeRhizoma fagopyri cymosi
H0571 Tu Gan Cao土甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1071 Gan Cao Gan Jin Gao甘草干浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0007 Huo Xue Teng活血藤 NASargentodoxa cuneata
H0825 Zhu Fu Shen朱茯神 Indian bread with pinePoria cocos
H1173 Hei Chou黑丑 Pharbitis seedSemen pharbitidis
H0980 Di Yu Tan地榆炭 Garden burnetSanguisorba officinalis