HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T20OEM	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	PIN1	Q13526	5 Reference(s)
T83YZD	Acetylcholinesterase	ACHE	P22303	4 Reference(s)
T58XLK	Tyrosine-protein phosphatase non-receptor type 1	PTPN1	P18031	1 Reference(s)
T12PIB	Lysosomal alpha-glucosidase	GAA	P10253	1 Reference(s)
T91T8I	Glucose-6-phosphatase catalytic subunit 1	G6PC1	P35575	1 Reference(s)
T58J2Y	Peroxisome proliferator-activated receptor gamma	PPARG	P37231	9 Reference(s)
T25Y64	Cholinesterase	BCHE	P06276	3 Reference(s)
T22OPB	Nuclear factor erythroid 2-related factor 2	NFE2L2	Q16236	6 Reference(s)
T81I4T	5'-AMP-activated protein kinase catalytic subunit alpha-1	PRKAA1	Q13131	2 Reference(s)
T21DZX	Amine oxidase [flavin-containing] A	MAOA	P21397	2 Reference(s)
T64X48	C-X-C chemokine receptor type 4	CXCR4	P61073	1 Reference(s)
T67ZT3	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	PTEN	P60484	3 Reference(s)
T31ZFD	Aldehyde oxidase	AOX1	Q06278	1 Reference(s)
T09INZ	Transient receptor potential cation channel subfamily A member 1	TRPA1	O75762	4 Reference(s)
T22NX4	Toll-like receptor 2	TLR2	O60603	2 Reference(s)
T76QBQ	CREB-regulated transcription coactivator 2	CRTC2	Q53ET0	1 Reference(s)
T60XJI	Transient receptor potential cation channel subfamily M member 8	TRPM8	Q7Z2W7	3 Reference(s)
T67KTV	Transient receptor potential cation channel subfamily V member 1	TRPV1	Q8NER1	1 Reference(s)
T25M2J	Anoctamin-1	ANO1	Q5XXA6	1 Reference(s)
T47H3O	Heat shock protein HSP 90-alpha	HSP90AA1	P07900	2 Reference(s)
T13KGH	Tyrosinase	TYR	P14679	3 Reference(s)
T40SWE	Glutamate carboxypeptidase 2	FOLH1	Q04609	1 Reference(s)
T49ORJ	Peroxisome proliferator-activated receptor alpha	PPARA	Q07869	6 Reference(s)
T70KPE	Transient receptor potential cation channel subfamily V member 3	TRPV3	Q8NET8	7 Reference(s)
T48J2C	Transient receptor potential cation channel subfamily M member 7	TRPM7	Q96QT4	3 Reference(s)
T70LAB	UDP-glucuronosyltransferase 1A9	UGT1A9	O60656	2 Reference(s)
T88LSZ	Aromatase	CYP19A1	P11511	3 Reference(s)
T57L0X	Oxysterols receptor LXR-alpha	NR1H3	Q13133	1 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	10 Reference(s)
T31U13	Cytochrome P450 2C19	CYP2C19	P33261	1 Reference(s)
T88TDZ	RAC-alpha serine/threonine-protein kinase	AKT1	P31749	5 Reference(s)
T82G3R	Integrin beta-3	ITGB3	P05106	1 Reference(s)
T78O6C	Mothers against decapentaplegic homolog 3	SMAD3	P84022	1 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	9 Reference(s)
T30VNV	Myeloperoxidase	MPO	P05164	4 Reference(s)
T62P0D	Collagenase 3	MMP13	P45452	1 Reference(s)
T09H2Z	Nitric oxide synthase, inducible	NOS2	P35228	10 Reference(s)
T74WWP	Peroxisome proliferator-activated receptor delta	PPARD	Q03181	1 Reference(s)
T14JSX	Plasminogen	PLG	P00747	1 Reference(s)
T67LRH	RNA-binding protein Musashi homolog 1	MSI1	O43347	1 Reference(s)
T63BQU	Cytochrome P450 1A1	CYP1A1	P04798	6 Reference(s)
T61OY3	UDP-glucuronosyltransferase 1A1	UGT1A1	P22309	1 Reference(s)
T62USB	Tumor necrosis factor receptor superfamily member 10A	TNFRSF10A	O00220	1 Reference(s)
T80D9C	Retinoic acid receptor gamma	RARG	P13631	1 Reference(s)
T37G49	Platelet-activating factor acetylhydrolase	PLA2G7	Q13093	1 Reference(s)
T77TY2	Protein disulfide-isomerase	P4HB	P07237	2 Reference(s)
T83DDX	Endothelial protein C receptor	PROCR	Q9UNN8	1 Reference(s)
T06VX0	MAP/microtubule affinity-regulating kinase 4	MARK4	Q96L34	1 Reference(s)
T24C0P	Bile acid receptor	NR1H4	Q96RI1	1 Reference(s)
T20RA0	Adenosine deaminase	ADA	P00813	1 Reference(s)
T74QXI	Serine/threonine-protein kinase mTOR	MTOR	P42345	1 Reference(s)
T93SFQ	NAD-dependent protein deacetylase sirtuin-1	SIRT1	Q96EB6	2 Reference(s)
T02QBS	Cytochrome P450 1A2	CYP1A2	P05177	2 Reference(s)
T69XVX	Cytochrome P450 1B1	CYP1B1	Q16678	2 Reference(s)
T80OJF	Interstitial collagenase	MMP1	P03956	2 Reference(s)
T84W8G	Aryl hydrocarbon receptor	AHR	P35869	3 Reference(s)
T14JSQ	Baculoviral IAP repeat-containing protein 2	BIRC2	Q13490	1 Reference(s)
T70YKV	Baculoviral IAP repeat-containing protein 3	BIRC3	Q13489	1 Reference(s)
T79KQO	NF-kappa-B inhibitor alpha	NFKBIA	P25963	3 Reference(s)
T49TDM	Matrix metalloproteinase-9	MMP9	P14780	2 Reference(s)
T40B7E	Calcium uniporter protein, mitochondrial	MCU	Q8NE86	1 Reference(s)
T07VJT	Multidrug and toxin extrusion protein 1	SLC47A1	Q96FL8	1 Reference(s)
T08Q7W	Prostaglandin G/H synthase 2	PTGS2	P35354	7 Reference(s)
T68XXK	4-aminobutyrate aminotransferase, mitochondrial	ABAT	P80404	2 Reference(s)
T40NB1	Ribosomal protein S6 kinase beta-1	RPS6KB1	P23443	1 Reference(s)
T16FZA	Prolyl endopeptidase	PREP	P48147	1 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	3 Reference(s)
T53YWQ	Pro-neuropeptide Y [Cleaved into: Neuropeptide Y	NPY	P01303	2 Reference(s)
T95LIF	Cannabinoid receptor 2	CNR2	P34972	11 Reference(s)
T88BCB	Glycerol-3-phosphate phosphatase	PGP	A6NDG6	1 Reference(s)
T17E49	Cannabinoid receptor 1	CNR1	P21554	1 Reference(s)
T48J1U	Aldo-keto reductase family 1 member C1	AKR1C1	Q04828	1 Reference(s)
T01QLH	Estrogen receptor	ESR1	P03372	1 Reference(s)
T21EGX	Multidrug resistance-associated protein 1	ABCC1	P33527	1 Reference(s)
T16A2X	Catalase	CAT	P04040	4 Reference(s)
T87UKX	Glucose-6-phosphate 1-dehydrogenase	G6PD	P11413	1 Reference(s)
T12WTT	Interleukin-5	IL5	P05113	4 Reference(s)
T30D9G	Superoxide dismutase [Cu-Zn]	SOD1	P00441	2 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	4 Reference(s)
T17CZC	Tissue factor	F3	P13726	1 Reference(s)
T29MD1	Mitogen-activated protein kinase 8	MAPK8	P45983	3 Reference(s)
T26KIE	Transcription factor AP-1	JUN	P05412	6 Reference(s)
T34DZ7	Interleukin-2	IL2	P60568	2 Reference(s)
T64BTV	Interleukin-1 beta	IL1B	P01584	4 Reference(s)
T06Q1R	Amine oxidase [flavin-containing] B	MAOB	P27338	1 Reference(s)
T70HTD	Cytochrome P450 2E1	CYP2E1	P05181	1 Reference(s)
T50V79	Interleukin-4	IL4	P05112	3 Reference(s)
T50GQE	Interleukin-13	IL13	P35225	1 Reference(s)
T86YQL	Prolactin	PRL	P01236	1 Reference(s)
T54SZZ	Endoplasmic reticulum chaperone BiP	HSPA5	P11021	1 Reference(s)
T20MBF	Serotransferrin	TF	P02787	1 Reference(s)
T39YFG	Trypsin-1	PRSS1	P07477	1 Reference(s)
T54WR0	Fatty acid-binding protein 5	FABP5	Q01469	1 Reference(s)
T21Q0D	3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMGCR	P04035	3 Reference(s)
T12T4H	Brain-derived neurotrophic factor	BDNF	P23560	1 Reference(s)
T07S0E	BDNF/NT-3 growth factors receptor	NTRK2	Q16620	1 Reference(s)
T90XYZ	C-reactive protein	CRP	P02741	1 Reference(s)
T51WGR	Pancreas/duodenum homeobox protein 1	PDX1	P52945	1 Reference(s)
T43NBB	Solute carrier family 2, facilitated glucose transporter member 2	SLC2A2	P11168	1 Reference(s)
T89L4V	Insulin	INS	P01308	2 Reference(s)
T38WWN	Serum paraoxonase/arylesterase 1	PON1	P27169	1 Reference(s)
T23YZF	Peptidyl-glycine alpha-amidating monooxygenase	PAM	P19021	1 Reference(s)
T77FOL	Neuromodulin	GAP43	P17677	1 Reference(s)
T93VFT	Endothelin-1	EDN1	P05305	1 Reference(s)
T36SOV	Plasminogen activator inhibitor 1	SERPINE1	P05121	1 Reference(s)
T02DEN	Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide	GCG	P01275	1 Reference(s)
T48UT8	Cholesteryl ester transfer protein	CETP	P11597	1 Reference(s)
T32HPO	Aspartyl aminopeptidase	DNPEP	Q9ULA0	1 Reference(s)
T20H9F	Stromelysin-1	MMP3	P08254	1 Reference(s)
T02YLA	Alpha-lactalbumin	LALBA	P00709	1 Reference(s)
T38T1U	Caspase-8	CASP8	Q14790	1 Reference(s)
T02GD4	Tumor necrosis factor ligand superfamily member 6	FASLG	P48023	1 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	9 Reference(s)
T64W2K	Cyclin-dependent kinase inhibitor 1	CDKN1A	P38936	1 Reference(s)
T76TED	Pro-opiomelanocortin	POMC	P01189	1 Reference(s)
T37JN5	Neutrophil gelatinase-associated lipocalin	LCN2	P80188	1 Reference(s)
T17UP9	C-C motif chemokine 2	CCL2	P13500	3 Reference(s)
T33OPP	Interleukin-6	IL6	P05231	2 Reference(s)
T92Q77	Type I iodothyronine deiodinase	DIO1	P49895	1 Reference(s)
T67HAF	Signal transducer and activator of transcription 1-alpha/beta	STAT1	P42224	2 Reference(s)
T07TMB	Cyclin-dependent kinase 1	CDK1	P06493	1 Reference(s)
T86ROZ	Heme oxygenase 1	HMOX1	P09601	3 Reference(s)
T48XM4	Glutathione S-transferase Mu 2	GSTM2	P28161	1 Reference(s)
T87WYU	Glutathione S-transferase Mu 1	GSTM1	P09488	1 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	4 Reference(s)
T10HL8	Intercellular adhesion molecule 1	ICAM1	P05362	4 Reference(s)
T50SX0	Nuclear receptor subfamily 1 group I member 2	NR1I2	O75469	1 Reference(s)
T41INV	Nuclear receptor subfamily 1 group I member 3	NR1I3	Q14994	1 Reference(s)
T59IKQ	Vascular cell adhesion protein 1	VCAM1	P19320	1 Reference(s)
T24U57	E-selectin	SELE	P16581	1 Reference(s)
T87DEX	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	XDH	P47989	2 Reference(s)
T54OSZ	Pleckstrin	PLEK	P08567	2 Reference(s)
T63FNY	NSFL1 cofactor p47	NSFL1C	Q9UNZ2	2 Reference(s)
T10ICM	Oxidized low-density lipoprotein receptor 1	OLR1	P78380	1 Reference(s)
T00H7Q	Neutrophil cytosol factor 1	NCF1	P14598	1 Reference(s)
T39RV3	Dual specificity mitogen-activated protein kinase kinase 1	MAP2K1	Q02750	2 Reference(s)
T19YQS	Complement C3	C3	P01024	1 Reference(s)
T80L9F	Complement C5	C5	P01031	1 Reference(s)
T92WFW	C-C motif chemokine 3	CCL3	P10147	2 Reference(s)
T23OTN	T-lymphocyte activation antigen CD80	CD80	P33681	2 Reference(s)
T47MPW	T-lymphocyte activation antigen CD86	CD86	P42081	2 Reference(s)
T68XO1	Indoleamine 2,3-dioxygenase 1	IDO1	P14902	2 Reference(s)
T83P5X	Inhibitor of nuclear factor kappa-B kinase subunit beta	IKBKB	O14920	2 Reference(s)
T70EJM	Eotaxin	CCL11	P51671	3 Reference(s)
T19CUN	Prothrombin	F2	P00734	1 Reference(s)
T77M4W	Adenosine receptor A2a	ADORA2A	P29274	1 Reference(s)
T46J84	Nicotinamide phosphoribosyltransferase	NAMPT	P43490	1 Reference(s)
T44LWL	Transcription factor p65	RELA	Q04206	4 Reference(s)
T05O6O	Estrogen receptor beta	ESR2	Q92731	1 Reference(s)
T23RXU	Glutathione reductase, mitochondrial	GSR	P00390	1 Reference(s)
T46AQJ	Glutathione S-transferase P	GSTP1	P09211	1 Reference(s)
T59DDI	Liver carboxylesterase 1	CES1	P23141	1 Reference(s)
T03NWF	Sterol O-acyltransferase 1	SOAT1	P35610	2 Reference(s)
T95RKQ	Sterol O-acyltransferase 2	SOAT2	O75908	1 Reference(s)
T35FQV	Microsomal triglyceride transfer protein large subunit	MTTP	P55157	1 Reference(s)
T30TYH	Phospholipase A2	PLA2G1B	P04054	1 Reference(s)
T23P74	Caspase-9	CASP9	P55211	2 Reference(s)
T27U96	Granulocyte-macrophage colony-stimulating factor	CSF2	P04141	1 Reference(s)
T02HSM	Neuroglobin	NGB	Q9NPG2	1 Reference(s)
T42EAZ	Vascular endothelial growth factor A	VEGFA	P15692	1 Reference(s)
T74LFK	Neurogenic locus notch homolog protein 1	NOTCH1	P46531	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	9 Reference(s)
T62ERY	Interleukin-1 receptor-associated kinase 4	IRAK4	Q9NWZ3	1 Reference(s)
T76AZQ	Histidine decarboxylase	HDC	P19113	1 Reference(s)
T60UPF	Parvalbumin alpha	PVALB	P20472	2 Reference(s)
T69RXK	Cytochrome P450 2C9	CYP2C9	P11712	1 Reference(s)
T18CUI	Neuron-specific calcium-binding protein hippocalcin	HPCA	P84074	1 Reference(s)
T92BZ2	Catenin beta-1	CTNNB1	P35222	2 Reference(s)
T54CIF	Interleukin-8	CXCL8	P10145	2 Reference(s)
T09BRP	NA	PKB_RS07820	NA	2 Reference(s)
T66S13	Dual specificity mitogen-activated protein kinase kinase 2	MAP2K2	P36507	1 Reference(s)
T08SJX	Astrocytic phosphoprotein PEA-15	PEA15	Q15121	1 Reference(s)
T38OQ4	Peroxiredoxin-2	PRDX2	P32119	1 Reference(s)
T38J3Y	Gamma-enolase	ENO2	P09104	1 Reference(s)
T25NSJ	Mitogen-activated protein kinase 3	MAPK3	P27361	2 Reference(s)
T80GUN	72 kDa type IV collagenase	MMP2	P08253	1 Reference(s)
T69NG6	Interleukin-10	IL10	P22301	2 Reference(s)
T51EKP	Apolipoprotein M	APOM	O95445	1 Reference(s)
T07VV7	Guanylin	GUCA2A	Q02747	1 Reference(s)
T80WPU	Protein ABHD15	ABHD15	Q6UXT9	1 Reference(s)
T56OUM	14-3-3 protein zeta/delta	YWHAZ	P63104	1 Reference(s)
T24YWQ	Insulin-degrading enzyme	IDE	P14735	1 Reference(s)
T34HYH	Interleukin-1 alpha	IL1A	P01583	1 Reference(s)
T39M6J	ATP-binding cassette sub-family C member 2	ABCC2	Q92887	1 Reference(s)
T92E71	Corticosteroid 11-beta-dehydrogenase isozyme 2	HSD11B2	P80365	1 Reference(s)
T10KMJ	Insulin-like growth factor II	IGF2	P01344	1 Reference(s)
T29XZT	Pulmonary surfactant-associated protein A1	SFTPA1	Q8IWL2	1 Reference(s)
T70SFS	Superoxide dismutase [Mn], mitochondrial	SOD2	P04179	1 Reference(s)
T13I7C	Transforming growth factor beta-2 proprotein	TGFB2	P61812	1 Reference(s)
T26EZU	Myc proto-oncogene protein	MYC	P01106	2 Reference(s)
T36I66	Metallothionein-2	MT2A	P02795	1 Reference(s)
T45WII	Transforming growth factor beta-3 proprotein [Cleaved into: Latency-associated peptide	TGFB3	P10600	1 Reference(s)
T74I49	Bcl-2-like protein 1	BCL2L1	Q07817	1 Reference(s)
T85AXP	Cytochrome P450 3A4	CYP3A4	P08684	1 Reference(s)
T28DIY	Immunoglobulin heavy constant epsilon	IGHE	P01854	1 Reference(s)
T06ADX	Tyrosine-protein kinase receptor UFO	AXL	P30530	1 Reference(s)
T53KY7	Cystic fibrosis transmembrane conductance regulator	CFTR	P13569	1 Reference(s)
T63GUB	Proto-oncogene c-Fos	FOS	P01100	2 Reference(s)
T04HTN	Cyclic AMP-dependent transcription factor ATF-3	ATF3	P18847	1 Reference(s)
T05XOE	Macrophage mannose receptor 1	MRC1	P22897	1 Reference(s)
T49PL1	Low-density lipoprotein receptor	LDLR	P01130	2 Reference(s)
T67RBZ	Mitochondrial uncoupling protein 2	UCP2	P55851	1 Reference(s)
T67HYX	Mitochondrial uncoupling protein 3	UCP3	P55916	1 Reference(s)
T19EKF	Cholecystokinin	CCK	P06307	1 Reference(s)
T19XSL	Fatty acid-binding protein, liver	FABP1	P07148	1 Reference(s)
T23APZ	Retinol-binding protein 2	RBP2	P50120	1 Reference(s)
T38K2W	Receptor tyrosine-protein kinase erbB-2	ERBB2	P04626	1 Reference(s)
T48YPL	Aquaporin-3	AQP3	Q92482	1 Reference(s)
T53SLQ	Aquaporin-9	AQP9	O43315	1 Reference(s)
T75EH8	Glucagon-like peptide 1 receptor	GLP1R	P43220	1 Reference(s)
T52VL6	Signal transducer and activator of transcription 5A	STAT5A	P42229	1 Reference(s)
T19K8W	Signal transducer and activator of transcription 5B	STAT5B	P51692	1 Reference(s)
T74JJN	Fatty acid synthase	FASN	P49327	2 Reference(s)
T98DNG	Natriuretic peptides A	NPPA	P01160	1 Reference(s)
T78ILO	Stearoyl-CoA desaturase	SCD	O00767	1 Reference(s)
T68IZC	Natriuretic peptides B	NPPB	P16860	1 Reference(s)
T02H9U	Nuclear factor of activated T-cells, cytoplasmic 4	NFATC4	Q14934	1 Reference(s)
T87QUW	Actin, aortic smooth muscle	ACTA2	P62736	1 Reference(s)
T71BDH	Mitogen-activated protein kinase 14	MAPK14	Q16539	2 Reference(s)
T53AOE	Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide	TGFB1	P01137	2 Reference(s)
T04WT7	Fibronectin	FN1	P02751	1 Reference(s)
T04H8Y	Beta-secretase 1	BACE1	P56817	1 Reference(s)
T57HGP	Tumor necrosis factor receptor superfamily member 6	FAS	P25445	1 Reference(s)
T07VO1	Steroid hormone receptor ERR1	ESRRA	P11474	2 Reference(s)
T99ARN	Forkhead box protein P3	FOXP3	Q9BZS1	1 Reference(s)
T18DUA	Tight junction protein ZO-1	TJP1	Q07157	1 Reference(s)
T10IWJ	Bone morphogenetic protein receptor type-2	BMPR2	Q13873	1 Reference(s)
T75PC7	NA	MIR21	NA	1 Reference(s)
T14DX3	Ribosomal protein S6 kinase alpha-3	RPS6KA3	P51812	1 Reference(s)
T66WWM	Claudin-2	CLDN2	P57739	1 Reference(s)
T74V1Z	Dual specificity mitogen-activated protein kinase kinase 7	MAP2K7	O14733	1 Reference(s)
T35KD8	C-C chemokine receptor type 3	CCR3	P51677	2 Reference(s)
T80DCQ	Aurora kinase A	AURKA	O14965	2 Reference(s)
T83PO9	Oligodendrocyte transcription factor 2	OLIG2	Q13516	1 Reference(s)
T90ORW	Bcl2-associated agonist of cell death	BAD	Q92934	1 Reference(s)
T33OSQ	Sterol regulatory element-binding protein 1	SREBF1	P36956	1 Reference(s)
T73S71	Apolipoprotein B-100	APOB	P04114	1 Reference(s)
T95IYZ	Adiponectin	ADIPOQ	Q15848	1 Reference(s)
T84XYQ	Polycystin-2	PKD2	Q13563	1 Reference(s)
T38EQ6	NAD(P)H dehydrogenase [quinone] 1	NQO1	P15559	1 Reference(s)

Herb ID: H0002	Chinese Character: 茴香
English Name: Fennel fruit	Latin Name: Foeniculum vulgare
Chinese Pin Yin : Hui Xiang	TCM-ID: TCMH1000
Therapeutic Function in Chinese : 温里	Therapeutic Function in English: For warming interior
Herb Function: Dispel cold and stop pain, regulate qi and harmonize the stomach

Herb Description

Related Targets (Total: 240)

Related Compounds (Total: 37)