HIT-result

Type	Detail
Target ID	T70EJM
Protein Name	Eotaxin
Uniprot ID	P51671
Protein Name Alias	C-C motif chemokine 11; Eosinophil chemotactic protein; Small-inducible cytokine A11
Gene ID	6356
Gene Symbol	CCL11
Gene Alias	SCYA11
TTD	T16888: Clinical Trial target
Pfam	PF00048
GO	0090647:modulation of age-related behavioral decline 0002548:monocyte chemotaxis 0045766:positive regulation of angiogenesis 0019221:cytokine-mediated signaling pathway 0007010:cytoskeleton organization 0008360:regulation of cell shape 0030838:positive regulation of actin filament polymerization 0046983:protein dimerization activity 0060444:branching involved in mammary gland duct morphogenesis 0030593:neutrophil chemotaxis 0048245:eosinophil chemotaxis 0006954:inflammatory response 0009615:response to virus 0007611:learning or memory 0005615:extracellular space 0061844:antimicrobial humoral immune response mediated by antimicrobial peptide 0009314:response to radiation 0050768:negative regulation of neurogenesis 0007165:signal transduction 0005576:extracellular region 0006468:protein phosphorylation 0001938:positive regulation of endothelial cell proliferation 0048018:receptor ligand activity 0071346:cellular response to interferon-gamma 0031640:killing of cells of other organism 0070371:ERK1 and ERK2 cascade 0008009:chemokine activity 0002544:chronic inflammatory response 0002551:mast cell chemotaxis 0006874:cellular calcium ion homeostasis 0007015:actin filament organization 0030335:positive regulation of cell migration 0071356:cellular response to tumor necrosis factor 0035962:response to interleukin-13 0070670:response to interleukin-4 0070374:positive regulation of ERK1 and ERK2 cascade 0048247:lymphocyte chemotaxis 0043547:positive regulation of GTPase activity 0007155:cell adhesion 0007186:G protein-coupled receptor signaling pathway 0070098:chemokine-mediated signaling pathway 0071347:cellular response to interleukin-1 0006935:chemotaxis 0048020:CCR chemokine receptor binding 0031728:CCR3 chemokine receptor binding 0060763:mammary duct terminal end bud growth
PDB	1EOT ; 2MPM ; 2EOT
Drugbank	DB05429
KEGG	hsa:6356

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1075	Gan Cao Liu Jin Gao	甘草流浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1164	He Geng	荷梗	Hindu lotus petiole	Nelumbo nucifera
H0472	Shu Da Huang	熟大黄	NA	Rheum palmatum
H1073	Gan Cao Jie	甘草节	Glycyrrhiza uralensis fisch	Glycyrrhiza uralensis
H0951	Dan Shen Jin Gao	丹参浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0571	Tu Gan Cao	土甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H1067	Gan Cao Fen	甘草粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0949	Dan Shen	丹参	The root of red-rooted salvia	Salvia miltiorrhiza
H0673	Xin Jiang Zi Cao	新疆紫草	Arnebia root	Arnebia euchroma
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H1070	Gan Cao Gan Gao Fen	甘草干膏粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0016	Ji Xue Cao	积雪草	Asiatic pennywort	Centella asiatica
H0950	Dan Shen Gan Jin Gao	丹参干浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0083	Jiu Jie Cha	九节茶	Glabrous sarcandra	Sarcandra glabra
H0932	Ba Qia	菝葜	Chinaroot greenbrier	Smilax china
H0890	Chuan Xin Lian Nong Suo Ye	穿心莲浓缩液	Common andrographis	Andrographis paniculata
H0302	Ou Fen	藕粉	Hindu lotus large rhizome	Nelumbo nucifera
H1069	Gan Cao Gan Gao	甘草干膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0141	Lian Zi Xin	莲子心	Hindu lotus plumule	Nelumbo nucifera
H0614	Wu Zhao Long	五爪龙	Cairo morningglory	Ipomoea cairica
H0887	Chuan Xin Lian Gan Jin Gao	穿心莲干浸膏	Common andrographis	Andrographis paniculata
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0240	Mi Gan Cao	蜜甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1074	Gan Cao Jin Gao	甘草浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0444	Sheng Gan Cao	生甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0612	Cao Shan Hu Jin Gao	草珊瑚浸膏	NA	Sarcandra glabra
H0886	Chuan Xin Lian	穿心莲	Common andrographis	Andrographis paniculata
H0889	Chuan Xin Lian Jin Gao	穿心莲浸膏	Common andrographis	Andrographis paniculata
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0304	Ou Pian	藕片	Hindu lotus large rhizome	Nelumbo nucifera
H1169	He Ye	荷叶	Hindu lotus leaf	Nelumbo nucifera
H1066	Gan Cao	甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0035	Bai Su Zi	白苏子	Common perilla fruit	Perilla frutescens
H1071	Gan Cao Gan Jin Gao	甘草干浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0632	Xia Ku Cao	夏枯草	Common selfheal	Prunella vulgaris
H0219	Man Shan Hong	满山红	Dahurian rhododendron	Rhododendron dauricum
H0140	Lian Zi	莲子	Hindu lotus seed	Nelumbo nucifera
H0301	Ou	藕	Hindu lotus large rhizome	Nelumbo nucifera
H0496	Shui Ze Lan	水泽兰	NA	Lycopus lucidus
H0074	Jing Jie Tan	荆芥炭	NA	Schizonepetae herba
H0002	Hui Xiang	茴香	Fennel fruit	Foeniculum vulgare
H1072	Gan Cao Gao	甘草膏	Glycyrrhiza inflata	Glycyrrhiza uralensis

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 45)