Herb Description

Herb ID:   H0890 Chinese Character:   穿心莲浓缩液
English Name:  Common andrographis Latin Name:  Andrographis paniculata
Chinese Pin Yin :  Chuan Xin Lian Nong Suo Ye TCM-ID:  TCMH302
Therapeutic Function in Chinese :  NA Therapeutic Function in English:  NA
Herb Function:  NA

Related Targets  (Total: 218)

Target idProtein NameGene SymbolUniprot IDNo.of Literature Evidence
T97KFC Transcription factor jun-BJUNB P17275
1 Reference(s)
T49TDM Matrix metalloproteinase-9MMP9 P14780
4 Reference(s)
T80GUN 72 kDa type IV collagenaseMMP2 P08253
2 Reference(s)
T76GZS Oxytocin receptorOXTR P30559
1 Reference(s)
T20JZ2 Androgen receptorAR P10275
2 Reference(s)
T06RMZ Nuclear factor NF-kappa-B p105 subunitNFKB1 P19838
18 Reference(s)
T71BDH Mitogen-activated protein kinase 14MAPK14 Q16539
4 Reference(s)
T85AXP Cytochrome P450 3A4CYP3A4 P08684
2 Reference(s)
T83YZD AcetylcholinesteraseACHE P22303
5 Reference(s)
T04MBA Vascular endothelial growth factor receptor 2KDR P35968
2 Reference(s)
T56TXY Polyunsaturated fatty acid 5-lipoxygenaseALOX5 P09917
2 Reference(s)
T31U13 Cytochrome P450 2C19CYP2C19 P33261
2 Reference(s)
T25Y64 CholinesteraseBCHE P06276
3 Reference(s)
T02QBS Cytochrome P450 1A2CYP1A2 P05177
3 Reference(s)
T11BI7 Toll-like receptor 4TLR4 O00206
3 Reference(s)
T09BRP NAPKB_RS07820 NA
2 Reference(s)
T11ZYR Cytochrome P450 2D6CYP2D6 P10635
1 Reference(s)
T54X6V Intermediate conductance calcium-activated potassium channel protein 4KCNN4 O15554
1 Reference(s)
T12PIB Lysosomal alpha-glucosidaseGAA P10253
1 Reference(s)
T91T8I Glucose-6-phosphatase catalytic subunit 1G6PC1 P35575
2 Reference(s)
T58J2Y Peroxisome proliferator-activated receptor gammaPPARG P37231
3 Reference(s)
T85U8U Caspase-3CASP3 P42574
10 Reference(s)
T88AJI Hypoxia-inducible factor 1-alphaHIF1A Q16665
4 Reference(s)
T92BZ2 Catenin beta-1CTNNB1 P35222
2 Reference(s)
T62P0D Collagenase 3MMP13 P45452
1 Reference(s)
T91OUC Mucin-5ACMUC5AC P98088
2 Reference(s)
T22NX4 Toll-like receptor 2TLR2 O60603
2 Reference(s)
T76QBQ CREB-regulated transcription coactivator 2CRTC2 Q53ET0
1 Reference(s)
T13WH4 Interferon-induced, double-stranded RNA-activated protein kinaseEIF2AK2 P19525
8 Reference(s)
T49ORJ Peroxisome proliferator-activated receptor alphaPPARA Q07869
4 Reference(s)
T88LSZ AromataseCYP19A1 P11511
1 Reference(s)
T83SXS 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7HSD17B7 P56937
1 Reference(s)
T16UZ4 Dipeptidyl peptidase 4DPP4 P27487
1 Reference(s)
T50V79 Interleukin-4IL4 P05112
4 Reference(s)
T42EAZ Vascular endothelial growth factor AVEGFA P15692
8 Reference(s)
T10ICM Oxidized low-density lipoprotein receptor 1OLR1 P78380
1 Reference(s)
T48DAP 40S ribosomal protein S9RPS9 P46781
1 Reference(s)
T82ALJ Glycogen synthase kinase-3 betaGSK3B P49841
6 Reference(s)
T42D4V Histone deacetylase 1HDAC1 Q13547
1 Reference(s)
T64X48 C-X-C chemokine receptor type 4CXCR4 P61073
1 Reference(s)
T86MX7 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1CD38 P28907
1 Reference(s)
T32R5L Cyclin-dependent kinase 9CDK9 P50750
3 Reference(s)
T42PUG Solute carrier family 2, facilitated glucose transporter member 1SLC2A1 P11166
3 Reference(s)
T68HNO Glutathione S-transferase omega-1GSTO1 P78417
1 Reference(s)
T40DIM Corticosteroid 11-beta-dehydrogenase isozyme 1HSD11B1 P28845
1 Reference(s)
T87AXU ADP/ATP translocase 2SLC25A5 P05141
2 Reference(s)
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
6 Reference(s)
T05RAA Inhibitor of nuclear factor kappa-B kinase subunit alphaCHUK O15111
1 Reference(s)
T55IBP Zinc finger protein SNAI1SNAI1 O95863
1 Reference(s)
T33OPP Interleukin-6IL6 P05231
7 Reference(s)
T62USB Tumor necrosis factor receptor superfamily member 10ATNFRSF10A O00220
1 Reference(s)
T32PI2 Programmed cell death 1 ligand 1CD274 Q9NZQ7
1 Reference(s)
T40XWM Proto-oncogene tyrosine-protein kinase ROSROS1 P08922
1 Reference(s)
T51IKV DNA topoisomerase 2-alphaTOP2A P11388
1 Reference(s)
T87DEX Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenaseXDH P47989
4 Reference(s)
T74JJN Fatty acid synthaseFASN P49327
1 Reference(s)
T22OPB Nuclear factor erythroid 2-related factor 2NFE2L2 Q16236
5 Reference(s)
T62UOD Serine/threonine-protein kinase VRK1VRK1 Q99986
1 Reference(s)
T47H3O Heat shock protein HSP 90-alphaHSP90AA1 P07900
1 Reference(s)
T60B3R Glutathione S-transferase kappa 1GSTK1 Q9Y2Q3
1 Reference(s)
T67CB6 Transcriptional regulator ERGERG P11308
1 Reference(s)
T39M6J ATP-binding cassette sub-family C member 2ABCC2 Q92887
1 Reference(s)
T97FEF Broad substrate specificity ATP-binding cassette transporter ABCG2ABCG2 Q9UNQ0
1 Reference(s)
T11NOZ NAMIR132 NA
1 Reference(s)
T68DAN Histone deacetylase 9HDAC9 Q9UKV0
1 Reference(s)
T74QXI Serine/threonine-protein kinase mTORMTOR P42345
1 Reference(s)
T91AIW Receptor-type tyrosine-protein kinase FLT3FLT3 P36888
1 Reference(s)
T25M2J Anoctamin-1ANO1 Q5XXA6
1 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
8 Reference(s)
T21DZX Amine oxidase [flavin-containing] AMAOA P21397
2 Reference(s)
T29B10 Interleukin-17AIL17A Q16552
1 Reference(s)
T38O11 Cyclin-G-associated kinaseGAK O14976
1 Reference(s)
T77TY2 Protein disulfide-isomeraseP4HB P07237
1 Reference(s)
T63BQU Cytochrome P450 1A1CYP1A1 P04798
3 Reference(s)
T81I4T 5'-AMP-activated protein kinase catalytic subunit alpha-1PRKAA1 Q13131
2 Reference(s)
T34DZ7 Interleukin-2IL2 P60568
2 Reference(s)
T23VMI Tumor necrosis factorTNF P01375
9 Reference(s)
T44LWL Transcription factor p65RELA Q04206
5 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
15 Reference(s)
T22XGJ Alpha-1A adrenergic receptorADRA1A P35348
1 Reference(s)
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
11 Reference(s)
T55NB7 Dihydropyrimidinase-related protein 1CRMP1 Q14194
1 Reference(s)
T00CXT Prostaglandin G/H synthase 1PTGS1 P23219
2 Reference(s)
T99XQ3 DNA topoisomerase 1TOP1 P11387
2 Reference(s)
T68BGR Glial fibrillary acidic proteinGFAP P14136
1 Reference(s)
T46YMA Ras-related C3 botulinum toxin substrate 1RAC1 P63000
1 Reference(s)
T25NSJ Mitogen-activated protein kinase 3MAPK3 P27361
3 Reference(s)
T86ROZ Heme oxygenase 1HMOX1 P09601
4 Reference(s)
T93R42 Dipeptidyl peptidase 1CTSC P53634
1 Reference(s)
T29MD1 Mitogen-activated protein kinase 8MAPK8 P45983
2 Reference(s)
T54G8J Protein kinase C delta typePRKCD Q05655
1 Reference(s)
T82JWE Cellular tumor antigen p53TP53 P04637
8 Reference(s)
T80OJF Interstitial collagenaseMMP1 P03956
3 Reference(s)
T75HMM Induced myeloid leukemia cell differentiation protein Mcl-1MCL1 Q07820
3 Reference(s)
T17UP9 C-C motif chemokine 2CCL2 P13500
1 Reference(s)
T74D4Y CASP8 and FADD-like apoptosis regulatorCFLAR O15519
2 Reference(s)
T95K8Q Intestinal-type alkaline phosphataseALPI P09923
1 Reference(s)
T98FWP NF-kappa-B essential modulatorIKBKG Q9Y6K9
1 Reference(s)
T94VM4 17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Estradiol 17-beta-dehydrogenase 2) (EC 1.1.1.62) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239)HSD17B2 P37059
1 Reference(s)
T74I49 Bcl-2-like protein 1BCL2L1 Q07817
3 Reference(s)
T14LSK E3 ubiquitin-protein ligase XIAPXIAP P98170
2 Reference(s)
T79KQO NF-kappa-B inhibitor alphaNFKBIA P25963
2 Reference(s)
T42XY2 Insulin-like growth factor 1 receptorIGF1R P08069
2 Reference(s)
T23P74 Caspase-9CASP9 P55211
2 Reference(s)
T93WZG G1/S-specific cyclin-D1CCND1 P24385
6 Reference(s)
T09H2Z Nitric oxide synthase, inducibleNOS2 P35228
12 Reference(s)
T54VQA Cyclin-dependent kinase inhibitor 2ACDKN2A P42771
2 Reference(s)
T07TMB Cyclin-dependent kinase 1CDK1 P06493
2 Reference(s)
T86UXL Cyclin-A2CCNA2 P20248
1 Reference(s)
T24LXT G2/mitotic-specific cyclin-B1CCNB1 P14635
4 Reference(s)
T64W2K Cyclin-dependent kinase inhibitor 1CDKN1A P38936
9 Reference(s)
T80TUC Apoptosis regulator BAXBAX Q07812
10 Reference(s)
T35QZO Cytochrome cCYCS P99999
1 Reference(s)
T06PVX E3 ubiquitin-protein ligase Mdm2MDM2 Q00987
2 Reference(s)
T06IYF Adenomatous polyposis coli proteinAPC P25054
1 Reference(s)
T10HL8 Intercellular adhesion molecule 1ICAM1 P05362
4 Reference(s)
T50GQE Interleukin-13IL13 P35225
1 Reference(s)
T75H3W Cyclin-dependent kinase 2CDK2 P24941
2 Reference(s)
T10S5F Cyclin-dependent kinase 4CDK4 P11802
3 Reference(s)
T22IMH Cyclin-dependent kinase 6CDK6 Q00534
1 Reference(s)
T02WMA Ornithine decarboxylaseODC1 P11926
1 Reference(s)
T84P70 Urokinase-type plasminogen activatorPLAU P00749
2 Reference(s)
T36SOV Plasminogen activator inhibitor 1SERPINE1 P05121
1 Reference(s)
T62QDU Alpha- and gamma-adaptin-binding protein p34AAGAB Q6PD74
1 Reference(s)
T26KIE Transcription factor AP-1JUN P05412
6 Reference(s)
T63GUB Proto-oncogene c-FosFOS P01100
1 Reference(s)
T37VLU Interferon gammaIFNG P01579
3 Reference(s)
T88B8X Insulin receptorINSR P06213
2 Reference(s)
T68SE0 Solute carrier family 2, facilitated glucose transporter member 4SLC2A4 P14672
2 Reference(s)
T45G32 Proto-oncogene tyrosine-protein kinase SrcSRC P12931
2 Reference(s)
T21S10 Heterogeneous nuclear ribonucleoproteins A2/B1HNRNPA2B1 P22626
1 Reference(s)
T46K2X Heat shock 70 kDa protein 4HSPA4 P34932
1 Reference(s)
T13KGH TyrosinaseTYR P14679
1 Reference(s)
T47HTN Prostaglandin E synthasePTGES O14684
1 Reference(s)
T38K2W Receptor tyrosine-protein kinase erbB-2ERBB2 P04626
1 Reference(s)
T92AMR Hepatocyte growth factor receptorMET P08581
1 Reference(s)
T69NG6 Interleukin-10IL10 P22301
4 Reference(s)
T60GGR Serine/threonine-protein kinase TBK1TBK1 Q9UHD2
1 Reference(s)
T01E7W Aurora kinase BAURKB Q96GD4
1 Reference(s)
T77M4W Adenosine receptor A2aADORA2A P29274
2 Reference(s)
T62Y4H Protein kinase C epsilon typePRKCE Q02156
1 Reference(s)
T35LKG Adenosine receptor A1ADORA1 P30542
1 Reference(s)
T16UHV Nuclear factor of activated T-cells, cytoplasmic 1NFATC1 O95644
1 Reference(s)
T46AQJ Glutathione S-transferase PGSTP1 P09211
1 Reference(s)
T04TXM RegucalcinRGN Q15493
1 Reference(s)
T70EJM EotaxinCCL11 P51671
1 Reference(s)
T12WTT Interleukin-5IL5 P05113
1 Reference(s)
T31P1D Metalloproteinase inhibitor 1TIMP1 P01033
1 Reference(s)
T58TFI 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3PFKFB3 Q16875
1 Reference(s)
T07NML P-selectinSELP P16109
1 Reference(s)
T25H22 Protein kinase C beta typePRKCB P05771
1 Reference(s)
T69RXK Cytochrome P450 2C9CYP2C9 P11712
2 Reference(s)
T74LFK Neurogenic locus notch homolog protein 1NOTCH1 P46531
1 Reference(s)
T62ERY Interleukin-1 receptor-associated kinase 4IRAK4 Q9NWZ3
1 Reference(s)
T76AZQ Histidine decarboxylaseHDC P19113
1 Reference(s)
T73HMK Bcl-2-binding component 3, isoforms 1/2BBC3 Q9BXH1
1 Reference(s)
T54CIF Interleukin-8CXCL8 P10145
3 Reference(s)
T04WT7 FibronectinFN1 P02751
1 Reference(s)
T17CZC Tissue factorF3 P13726
1 Reference(s)
T67UWO C-C motif chemokine 26CCL26 Q9Y258
1 Reference(s)
T02IOG Cyclin-dependent kinase inhibitor 1BCDKN1B P46527
1 Reference(s)
T67LQK Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)MAPK11 Q15759
1 Reference(s)
T93PLN Serine/threonine-protein kinase/endoribonuclease IRE1ERN1 O75460
1 Reference(s)
T43N2D Epidermal growth factor receptorEGFR P00533
2 Reference(s)
T50VJF OsteopontinSPP1 P10451
1 Reference(s)
T53KRS E3 ubiquitin-protein ligase NEDD4-likeNEDD4L Q96PU5
1 Reference(s)
T38G9K TNF receptor-associated factor 2TRAF2 Q12933
1 Reference(s)
T51EKP Apolipoprotein MAPOM O95445
1 Reference(s)
T07VV7 GuanylinGUCA2A Q02747
1 Reference(s)
T67ZT3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENPTEN P60484
1 Reference(s)
T80WPU Protein ABHD15ABHD15 Q6UXT9
1 Reference(s)
T56OUM 14-3-3 protein zeta/deltaYWHAZ P63104
1 Reference(s)
T24YWQ Insulin-degrading enzymeIDE P14735
1 Reference(s)
T34HYH Interleukin-1 alphaIL1A P01583
1 Reference(s)
T04TWI CD40 ligandCD40LG P29965
1 Reference(s)
T41TXS Retinoblastoma-associated proteinRB1 P06400
1 Reference(s)
T92UBJ Acetyl-CoA carboxylase 1ACACA Q13085
1 Reference(s)
T87WMV Sodium/potassium-transporting ATPase subunit gammaFXYD2 P54710
1 Reference(s)
T00KKS Sodium/iodide cotransporterSLC5A5 Q92911
1 Reference(s)
T38BR0 G1/S-specific cyclin-D2CCND2 P30279
2 Reference(s)
T78ILO Stearoyl-CoA desaturaseSCD O00767
1 Reference(s)
T96G89 Fatty acid-binding protein, adipocyteFABP4 P15090
1 Reference(s)
T90ORW Bcl2-associated agonist of cell deathBAD Q92934
1 Reference(s)
T89L4V InsulinINS P01308
1 Reference(s)
T04UTZ G1/S-specific cyclin-E1CCNE1 P24864
1 Reference(s)
T22I6G Cyclin-dependent kinase 4 inhibitor C (Cyclin-dependent kinase 6 inhibitor) (p18-INK4c) (p18-INK6)CDKN2C P42773
1 Reference(s)
T25S1M Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1) (Fragment)p27 kip1 O43806
1 Reference(s)
T01QLH Estrogen receptorESR1 P03372
2 Reference(s)
T05PKX Steroid 17-alpha-hydroxylase/17,20 lyaseCYP17A1 P05093
1 Reference(s)
T74ETU Steroid 21-hydroxylaseCYP21A2 P08686
1 Reference(s)
T65S3S Tyrosine-protein kinase JAK2JAK2 O60674
1 Reference(s)
T27LTU C5a anaphylatoxin chemotactic receptor 1C5AR1 P21730
1 Reference(s)
T00QMT NAMIR15B NA
1 Reference(s)
T06ADX Tyrosine-protein kinase receptor UFOAXL P30530
1 Reference(s)
T30L86 Tumor necrosis factor receptor superfamily member 10BTNFRSF10B O14763
1 Reference(s)
T26EZU Myc proto-oncogene proteinMYC P01106
1 Reference(s)
T52RGZ Growth/differentiation factor 15GDF15 Q99988
1 Reference(s)
T40JZG GPI-anchor transamidasePIGK Q92643
1 Reference(s)
T20TPU Histone acetyltransferase KAT2BKAT2B Q92831
1 Reference(s)
T57HGP Tumor necrosis factor receptor superfamily member 6FAS P25445
1 Reference(s)
T68AKE Zinc fingers and homeoboxes protein 2ZHX2 Q9Y6X8
1 Reference(s)
T73LPO Poly [ADP-ribose] polymerase 1PARP1 P09874
1 Reference(s)
T10K5R NAMIR203A NA
1 Reference(s)
T66WWM Claudin-2CLDN2 P57739
2 Reference(s)
T78O6C Mothers against decapentaplegic homolog 3SMAD3 P84022
1 Reference(s)
T92HNO High mobility group protein B1HMGB1 P09429
1 Reference(s)
T78IOY Telomerase reverse transcriptaseTERT O14746
1 Reference(s)
T41BXR NAD-dependent protein deacetylase sirtuin-3, mitochondrialSIRT3 Q9NTG7
1 Reference(s)
T41DXP PleiotrophinPTN P21246
1 Reference(s)
T62RLH NAMIR384 NA
1 Reference(s)
T60UPF Parvalbumin alphaPVALB P20472
2 Reference(s)
T18CUI Neuron-specific calcium-binding protein hippocalcinHPCA P84074
1 Reference(s)
T39RV3 Dual specificity mitogen-activated protein kinase kinase 1MAP2K1 Q02750
1 Reference(s)
T66S13 Dual specificity mitogen-activated protein kinase kinase 2MAP2K2 P36507
1 Reference(s)
T08SJX Astrocytic phosphoprotein PEA-15PEA15 Q15121
1 Reference(s)
T38OQ4 Peroxiredoxin-2PRDX2 P32119
1 Reference(s)
T38J3Y Gamma-enolaseENO2 P09104
1 Reference(s)
T49PL1 Low-density lipoprotein receptorLDLR P01130
1 Reference(s)

Related Compounds  (Total: 13)

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C0899
Name: Andrographolide
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C1203
Name: Caffeic Acid
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C1231
Name: Chlorogenic Acid
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C0485
Name: Wogonin
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C0285
Name: Palmitic Acid