HIT-result

Type	Detail
Target ID	T38G9K
Protein Name	TNF receptor-associated factor 2
Uniprot ID	Q12933
Protein Name Alias	EC 2.3.2.27; E3 ubiquitin-protein ligase TRAF2; RING-type E3 ubiquitin transferase TRAF2; Tumor necrosis factor type 2 receptor-associated protein 3
Gene ID	7186
Gene Symbol	TRAF2
Gene Alias	TRAP3
TTD	NA
Pfam	PF00097 ; PF02176 ; PF16673
GO	0002726:positive regulation of T cell cytokine production 0031996:thioesterase binding 0007250:activation of NF-kappaB-inducing kinase activity 0051091:positive regulation of DNA-binding transcription factor activity 0097300:programmed necrotic cell death 0031625:ubiquitin protein ligase binding 0019903:protein phosphatase binding 0046625:sphingolipid binding 2001238:positive regulation of extrinsic apoptotic signaling pathway 0043120:tumor necrosis factor binding 0033209:tumor necrosis factor-mediated signaling pathway 0016579:protein deubiquitination 0043122:regulation of I-kappaB kinase/NF-kappaB signaling 0034351:negative regulation of glial cell apoptotic process 0005164:tumor necrosis factor receptor binding 0097057:TRAF2-GSTP1 complex 1903265:positive regulation of tumor necrosis factor-mediated signaling pathway 0030163:protein catabolic process 0031435:mitogen-activated protein kinase kinase kinase binding 0005829:cytosol 0042981:regulation of apoptotic process 0042802:identical protein binding 0044877:protein-containing complex binding 0030674:protein-macromolecule adaptor activity 1990604:IRE1-TRAF2-ASK1 complex 0032743:positive regulation of interleukin-2 production 0065003:protein-containing complex assembly 0034622:cellular protein-containing complex assembly 0070059:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0043254:regulation of protein-containing complex assembly 0002637:regulation of immunoglobulin production 0005654:nucleoplasm 0071732:cellular response to nitric oxide 0002947:tumor necrosis factor receptor superfamily complex 0019899:enzyme binding 0071550:death-inducing signaling complex assembly 1901215:negative regulation of neuron death 0046330:positive regulation of JNK cascade 0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process 0008270:zinc ion binding 0005174:CD40 receptor binding 0004842:ubiquitin-protein transferase activity 0005938:cell cortex 0007249:I-kappaB kinase/NF-kappaB signaling 0000151:ubiquitin ligase complex 0043507:positive regulation of JUN kinase activity 0070534:protein K63-linked ubiquitination 1902041:regulation of extrinsic apoptotic signaling pathway via death domain receptors 0019901:protein kinase binding 1903721:positive regulation of I-kappaB phosphorylation 0045121:membrane raft 0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling 0051092:positive regulation of NF-kappaB transcription factor activity 0007165:signal transduction 0051865:protein autoubiquitination 0009898:cytoplasmic side of plasma membrane 0010803:regulation of tumor necrosis factor-mediated signaling pathway 0034976:response to endoplasmic reticulum stress 0012506:vesicle membrane 1902042:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 0035631:CD40 receptor complex
PDB	1F3V ; 1QSC ; 1CA4 ; 1D01 ; 3KNV ; 3M06 ; 1D0J ; 1CZZ ; 1D00 ; 3M0A ; 3M0D ; 1CA9 ; 1D0A ; 1CZY
Drugbank	NA
KEGG	hsa:7186

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Name: Resveratrol

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Name: Wogonin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0531	Tao Zhi	桃枝	Peach juvenile branch	Prunus persica
H0269	Mu Gua	木瓜	Chinese floweringquince	Chaenomeles sinensis
H0693	Xue Xie	血蝎	Dragon's blood	Daemonorops draco
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H1222	Huai Hua	槐花	flower bud of japanese pagodatree	Sophora japonica
H1242	Huang Lian Gan Jin Gao	黄连干浸膏	Coptis deltoidea	Coptis chinensis
H0665	Chai Hu Shao	柴胡梢	Chinese thorowax	Bupleurum chinense
H0626	Xi Nan Huang Qin	西南黄芩	Yunnan skullcap	Scutellaria amoena
H0889	Chuan Xin Lian Jin Gao	穿心莲浸膏	Common andrographis	Andrographis paniculata
H1227	Huai Zhi	槐枝	NA	Sophora japonica
H0932	Ba Qia	菝葜	Chinaroot greenbrier	Smilax china
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H1247	Huang Qi	黄芪	Membranous milkvetch	Astragalus membranaceus
H0818	Zhi Zi	栀子	Cape jasmine fruit	Gardenia jasminoides
H1248	Huang Qi Gan Jin Gao	黄芪干浸膏	Membranous milkvetch	Astragalus membranaceus
H0164	Ban Zhi Lian	半枝莲	Barbed skullcap	Scutellaria barbata
H0887	Chuan Xin Lian Gan Jin Gao	穿心莲干浸膏	Common andrographis	Andrographis paniculata
H0883	Chuan She Gan	川射干	Blackberrylily	Belamcanda chinensis
H0765	Chi Dou	赤豆	Assuki bean	Vigna angularis
H1016	Du Zhong Tan	杜仲炭	Eucommia	Eucommia ulmoides
H0270	Mu Hu Die	木蝴蝶	Indian trumpetflower	Oroxylum indicum
H0424	Shan Zhi	山栀	Cape jasmine	Gardenia jasminoides
H0529	Tao Ren	桃仁	Peach kernel	Prunus persica
H0530	Tao Ren Shuang	桃仁霜	Peach kernel	Prunus persica
H0029	Jiang Huang Lian	姜黄连	Coptis deltoidea	Coptis chinensis
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H0819	Zhi Zi Jin Gao	栀子浸膏	Cape jasmine fruit	Gardenia jasminoides
H1017	Du Zhong Ye	杜仲叶	Eucommia leaf	Eucommia ulmoides
H0472	Shu Da Huang	熟大黄	NA	Rheum palmatum
H1250	Huang Qi Ti Qu Ye	黄芪提取液	Membranous milkvetch	Astragalus membranaceus
H1253	Huang Qin Jin Gao Fen	黄芩浸膏粉	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H0744	Yin Chai Hu	银柴胡	Lanceolate starwort	Stellaria dichotoma var. lanceolata
H0551	Cang Zhu	苍术	Swordlike atractylodes	Atractylodes lancea
H0890	Chuan Xin Lian Nong Suo Ye	穿心莲浓缩液	Common andrographis	Andrographis paniculata
H0226	Man Yue Mei	蔓越莓	Cranberry	Vaccinium oxycoccos
H0760	Yu Huang Lian	萸黄连	Coptis deltoidea	Coptis chinensis
H0891	Chuan Xin Lian Ye	穿心莲叶	Powder of green chiretta leaves	Andrographis herba
H0659	Chai Hu Jin Gao	柴胡浸膏	Chinese thorowax	Bupleurum chinense
H1166	He Shou Wu	何首乌	Tuber fleeceflower	Polygonum multiflorum
H0682	Xiong Huang Lian	雄黄连	Coptis deltoidea	Coptis chinensis
H1249	Huang Qi Jin Gao	黄芪浸膏	Membranous milkvetch	Astragalus membranaceus
H0650	Chai Hu	柴胡	Chinese thorowax	Bupleurum chinense
H0785	Ze Xi Huang Lian	择细黄连	Coptis deltoidea	Coptis chinensis
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0886	Chuan Xin Lian	穿心莲	Common andrographis	Andrographis paniculata
H0872	Chuan Huang Lian	川黄连	rhizome of chinese goldthread	Coptis chinensis
H0527	Tao	桃	Peach	Prunus persica
H0617	Qian Cao Teng	茜草藤	NA	Rubia cordifolia
H1117	Guan Zhong	贯众	Male fern rhizome	Dryopteris crassirhizoma
H1030	Fang Feng	防风	Divaricate saposhnikovia	Saposhnikovia divaricata
H1254	Huang Qin Tan	黄芩炭	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H1243	Huang Lian Xu	黄连须	Coptis deltoidea	Coptis chinensis
H1213	Hu Zhang	虎杖	Japanese fleeceflower	Polygonum cuspidatum
H0432	She Gan	射干	Blackberrylily	Belamcanda chinensis
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H0714	Yan Tai Chai Hu	烟台柴胡	Chinese thorowax	Bupleurum chinense
H0310	Pian Qin	片芩	Scutellaria amoena	Scutellaria baicalensis
H1225	Huai Mi	槐米	NA	Sophora japonica
H1241	Huang Lian	黄连	Coptis deltoidea	Coptis chinensis
H1224	Huai Jiao	槐角	pod of japanese pagodatree	Sophora japonica
H1252	Huang Qin Jin Gao	黄芩浸膏	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H0416	Shan Shen	山参	NA	Panax ginseng
H0434	She Pu Tao	蛇葡萄	Ampelopsis	Ampelopsis brevipedunculata
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba
H1015	Du Zhong	杜仲	Eucommia	Eucommia ulmoides
H0082	Jiu Huang Lian	酒黄连	Coptis deltoidea	Coptis chinensis
H1251	Huang Qin	黄芩	Root of Baikal skullcaap	Scutellaria baicalensis

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 70)