HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T31JL4	Melanocyte-stimulating hormone receptor	MC1R	Q01726	2 Reference(s)
T02QBS	Cytochrome P450 1A2	CYP1A2	P05177	2 Reference(s)
T12BGL	Cytochrome P450 2A6	CYP2A6	P11509	1 Reference(s)
T08Q7W	Prostaglandin G/H synthase 2	PTGS2	P35354	4 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	10 Reference(s)
T23P74	Caspase-9	CASP9	P55211	4 Reference(s)
T38T1U	Caspase-8	CASP8	Q14790	2 Reference(s)
T50SJ8	5'-AMP-activated protein kinase catalytic subunit alpha-2	PRKAA2	P54646	1 Reference(s)
T38EQ6	NAD(P)H dehydrogenase [quinone] 1	NQO1	P15559	1 Reference(s)
T06Q1R	Amine oxidase [flavin-containing] B	MAOB	P27338	1 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	2 Reference(s)
T88AJI	Hypoxia-inducible factor 1-alpha	HIF1A	Q16665	1 Reference(s)
T92BZ2	Catenin beta-1	CTNNB1	P35222	1 Reference(s)
T62P0D	Collagenase 3	MMP13	P45452	1 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	10 Reference(s)
T91OUC	Mucin-5AC	MUC5AC	P98088	1 Reference(s)
T31U13	Cytochrome P450 2C19	CYP2C19	P33261	1 Reference(s)
T49ORJ	Peroxisome proliferator-activated receptor alpha	PPARA	Q07869	2 Reference(s)
T17E49	Cannabinoid receptor 1	CNR1	P21554	1 Reference(s)
T47H3O	Heat shock protein HSP 90-alpha	HSP90AA1	P07900	2 Reference(s)
T25RTY	C-C motif chemokine 22	CCL22	O00626	1 Reference(s)
T77O2V	Mannose-1-phosphate guanyltransferase beta	GMPPB	Q9Y5P6	1 Reference(s)
T75RAR	Dual oxidase 2	DUOX2	Q9NRD8	1 Reference(s)
T05WWN	Corticoliberin	CRH	P06850	1 Reference(s)
T83YZD	Acetylcholinesterase	ACHE	P22303	2 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	3 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	8 Reference(s)
T53AOE	Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide	TGFB1	P01137	1 Reference(s)
T44LWL	Transcription factor p65	RELA	Q04206	1 Reference(s)
T54G8J	Protein kinase C delta type	PRKCD	Q05655	1 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	3 Reference(s)
T80OJF	Interstitial collagenase	MMP1	P03956	1 Reference(s)
T75HMM	Induced myeloid leukemia cell differentiation protein Mcl-1	MCL1	Q07820	1 Reference(s)
T17UP9	C-C motif chemokine 2	CCL2	P13500	1 Reference(s)
T32R5L	Cyclin-dependent kinase 9	CDK9	P50750	1 Reference(s)
T01HJQ	Calreticulin	CALR	P27797	1 Reference(s)
T86J48	Sodium/glucose cotransporter 1	SLC5A1	P13866	2 Reference(s)
T00H7Q	Neutrophil cytosol factor 1	NCF1	P14598	1 Reference(s)
T26KIE	Transcription factor AP-1	JUN	P05412	2 Reference(s)
T44FET	Cytochrome P450 2B10	Cyp2b10	P12791	1 Reference(s)
T01QLH	Estrogen receptor	ESR1	P03372	1 Reference(s)
T05O6O	Estrogen receptor beta	ESR2	Q92731	1 Reference(s)
T14ENF	Microtubule-associated protein 2	MAP2	P11137	1 Reference(s)
T78ZF2	Protein kinase C alpha type	PRKCA	P17252	1 Reference(s)
T93VFT	Endothelin-1	EDN1	P05305	1 Reference(s)
T75B9S	Cyclic AMP-responsive element-binding protein 1	CREB1	P16220	1 Reference(s)
T09H2Z	Nitric oxide synthase, inducible	NOS2	P35228	2 Reference(s)
T82ALJ	Glycogen synthase kinase-3 beta	GSK3B	P49841	2 Reference(s)
T93WZG	G1/S-specific cyclin-D1	CCND1	P24385	1 Reference(s)
T73HMK	Bcl-2-binding component 3, isoforms 1/2	BBC3	Q9BXH1	1 Reference(s)
T64W2K	Cyclin-dependent kinase inhibitor 1	CDKN1A	P38936	1 Reference(s)
T33OPP	Interleukin-6	IL6	P05231	1 Reference(s)
T54CIF	Interleukin-8	CXCL8	P10145	1 Reference(s)
T04MBA	Vascular endothelial growth factor receptor 2	KDR	P35968	1 Reference(s)
T88TDZ	RAC-alpha serine/threonine-protein kinase	AKT1	P31749	1 Reference(s)
T00CXT	Prostaglandin G/H synthase 1	PTGS1	P23219	1 Reference(s)
T04WT7	Fibronectin	FN1	P02751	1 Reference(s)
T17CZC	Tissue factor	F3	P13726	2 Reference(s)
T67UWO	C-C motif chemokine 26	CCL26	Q9Y258	1 Reference(s)
T49TDM	Matrix metalloproteinase-9	MMP9	P14780	1 Reference(s)
T02IOG	Cyclin-dependent kinase inhibitor 1B	CDKN1B	P46527	1 Reference(s)
T67LQK	Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)	MAPK11	Q15759	1 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	2 Reference(s)
T93PLN	Serine/threonine-protein kinase/endoribonuclease IRE1	ERN1	O75460	1 Reference(s)
T42EAZ	Vascular endothelial growth factor A	VEGFA	P15692	2 Reference(s)
T74D4Y	CASP8 and FADD-like apoptosis regulator	CFLAR	O15519	1 Reference(s)
T43N2D	Epidermal growth factor receptor	EGFR	P00533	1 Reference(s)
T50VJF	Osteopontin	SPP1	P10451	1 Reference(s)
T53KRS	E3 ubiquitin-protein ligase NEDD4-like	NEDD4L	Q96PU5	1 Reference(s)
T10S5F	Cyclin-dependent kinase 4	CDK4	P11802	1 Reference(s)
T38G9K	TNF receptor-associated factor 2	TRAF2	Q12933	1 Reference(s)
T96OOK	Signal transducer and activator of transcription 3	STAT3	P40763	1 Reference(s)
T89GCM	Inward rectifier potassium channel 2	KCNJ2	P63252	1 Reference(s)
T90XYZ	C-reactive protein	CRP	P02741	1 Reference(s)
T43Y5O	D(3) dopamine receptor	DRD3	P35462	1 Reference(s)
T44S1A	Apolipoprotein A-I	APOA1	P02647	1 Reference(s)
T74P7I	G-protein coupled bile acid receptor 1	GPBAR1	Q8TDU6	1 Reference(s)
T68WYW	von Willebrand factor	VWF	P04275	1 Reference(s)
T09INZ	Transient receptor potential cation channel subfamily A member 1	TRPA1	O75762	1 Reference(s)
T48TW0	Platelet glycoprotein 4	CD36	P16671	1 Reference(s)

Herb ID: H1030	Chinese Character: 防风
English Name: Divaricate saposhnikovia	Latin Name: Saposhnikovia divaricata
Chinese Pin Yin : Fang Feng	TCM-ID: TCMH562
Therapeutic Function in Chinese : 解表	Therapeutic Function in English: For relieving exterior syndrome
Herb Function: Induce diaphoresis, dispel wind, alleviate rheumatic conditions, and relieve spasm

Herb Description

Related Targets (Total: 80)

Related Compounds (Total: 16)