HIT-result

Target Description

Type	Detail
Target ID	T31JL4
Protein Name	Melanocyte-stimulating hormone receptor
Uniprot ID	Q01726
Protein Name Alias	MSH-R; Melanocortin receptor 1; MC1-R
Gene ID	4157
Gene Symbol	MC1R
Gene Alias	MSHR
TTD	T35842: Successful target
Pfam	PF00001
GO	0007275:multicellular organism development 0070914:UV-damage excision repair 0035556:intracellular signal transduction 0019222:regulation of metabolic process 0010739:positive regulation of protein kinase A signaling 0031625:ubiquitin protein ligase binding 0051897:positive regulation of protein kinase B signaling 0009650:UV protection 0004977:melanocortin receptor activity 0007189:adenylate cyclase-activating G protein-coupled receptor signaling pathway 0007187:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 0005887:integral component of plasma membrane 0002862:negative regulation of inflammatory response to antigenic stimulus 0005886:plasma membrane 0008528:G protein-coupled peptide receptor activity 0004930:G protein-coupled receptor activity 0004980:melanocyte-stimulating hormone receptor activity 0005737:cytoplasm 0032720:negative regulation of tumor necrosis factor production 0090037:positive regulation of protein kinase C signaling 0007186:G protein-coupled receptor signaling pathway 0043473:pigmentation 0045944:positive regulation of transcription by RNA polymerase II
PDB	NA
Drugbank	DB11653 ; DB05479 ; DB04931
KEGG	hsa:4157

Type

Detail

Target ID

T31JL4

Protein Name

Melanocyte-stimulating hormone receptor

Uniprot ID

Q01726

Protein Name Alias

MSH-R; Melanocortin receptor 1; MC1-R

Gene ID

4157

Gene Symbol

MC1R

Gene Alias

MSHR

TTD

T35842: Successful target

Pfam

PF00001

0007275:multicellular organism development

0070914:UV-damage excision repair

0035556:intracellular signal transduction

0019222:regulation of metabolic process

0010739:positive regulation of protein kinase A signaling

0031625:ubiquitin protein ligase binding

0051897:positive regulation of protein kinase B signaling

0009650:UV protection

0004977:melanocortin receptor activity

0007189:adenylate cyclase-activating G protein-coupled receptor signaling pathway

0007187:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

0005887:integral component of plasma membrane

0002862:negative regulation of inflammatory response to antigenic stimulus

0005886:plasma membrane

0008528:G protein-coupled peptide receptor activity

0004930:G protein-coupled receptor activity

0004980:melanocyte-stimulating hormone receptor activity

0005737:cytoplasm

0032720:negative regulation of tumor necrosis factor production

0090037:positive regulation of protein kinase C signaling

0007186:G protein-coupled receptor signaling pathway

0043473:pigmentation

0045944:positive regulation of transcription by RNA polymerase II

PDB

Drugbank

DB11653 ; DB05479 ; DB04931

KEGG

hsa:4157

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0387	San Ya Ku	三桠苦	Common rue	Ruta graveolens
H0256	Ming Dang Shen	明党参	Medicinal changium	Changium smyrnioides
H0956	Dang Gui Gan Jin Gao	当归干浸膏	NA	Angelica sinensis
H0242	Bei Sha Shen Liu Jin Gao	北沙参流浸膏	Glehnia littoralis	Glehnia littoralis
H0312	Po Gu Zhi	破故纸	fruit of malaytea scurfpea	Fructus psoraleae corylifoliae
H1009	Du Huo	独活	Doubleteeth pubescent angelica	Angelica pubescens
H0868	Chuan Du Huo	川独活	Doubleteeth pubescent angelica	Angelica pubescens
H0400	Sha Shen	沙参	Glehnia root	Radix glehniae
H0433	She Ma Zi	蛇麻子	Common cnidium fruit	Cnidium monnieri
H0589	Wang Bu Liu Xing	王不留行	Cowherb	Vaccaria segetalis
H0774	Yun Xiang Jin Gao	芸香浸膏	Ruta	Ruta graveolens
H0595	Wu Hua Guo	无花果	Fig	Ficus carica
H0526	Tang Gu Te Wu Tou	唐古特乌头	NA	Aconitum tanguticum
H0615	Wu Zhi Mao Tao	五指毛桃	five-finger fig root	Ficus simplicissima
H0456	Bu Gu Zhi	补骨脂	Malaytea scurfpea	Psoralea corylifolia
H0955	Dang Gui	当归	Chinese angelica	Angelica sinensis
H1030	Fang Feng	防风	Divaricate saposhnikovia	Saposhnikovia divaricata
H1090	Gao Ben	藁本	Chinese ligusticum	Ligusticum sinense
H0430	She Chuang Zi	蛇床子	Common cnidium	Cnidium monnieri
H0239	Bei Sha Shen	北沙参	Coastal glehnia	Glehnia littoralis

Target Description