Herb Description
| Herb ID: H0615 | Chinese Character: 五指毛桃 |
| English Name: five-finger fig root | Latin Name: Ficus simplicissima |
| Chinese Pin Yin : Wu Zhi Mao Tao | TCM-ID: TCMH2215 |
| Therapeutic Function in Chinese : NA | Therapeutic Function in English: NA |
| Herb Function: NA | |
Related Targets (Total: 108)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T12PIB | Lysosomal alpha-glucosidase | GAA |
P10253 |
1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
3 Reference(s) |
| T91T8I | Glucose-6-phosphatase catalytic subunit 1 | G6PC1 |
P35575 |
1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
3 Reference(s) |
| T25Y64 | Cholinesterase | BCHE |
P06276 |
1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
2 Reference(s) |
| T63VZZ | Metastasis-suppressor KiSS-1 | KISS1 |
Q15726 |
1 Reference(s) |
| T35LKG | Adenosine receptor A1 | ADORA1 |
P30542 |
1 Reference(s) |
| T77M4W | Adenosine receptor A2a | ADORA2A |
P29274 |
3 Reference(s) |
| T20NCI | Serine-protein kinase ATM | ATM |
Q13315 |
2 Reference(s) |
| T74RBE | Inositol 1,4,5-trisphosphate receptor type 1 | ITPR1 |
Q14643 |
2 Reference(s) |
| T84VZG | Ryanodine receptor 1 | RYR1 |
P21817 |
12 Reference(s) |
| T19CTK | Serine/threonine-protein kinase ATR | ATR |
Q13535 |
3 Reference(s) |
| T13KGH | Tyrosinase | TYR |
P14679 |
1 Reference(s) |
| T20RA0 | Adenosine deaminase | ADA |
P00813 |
1 Reference(s) |
| T67OMA | Ryanodine receptor 2 | RYR2 |
Q92736 |
1 Reference(s) |
| T45LZI | Calcium release-activated calcium channel protein 1 | ORAI1 |
Q96D31 |
1 Reference(s) |
| T73LPO | Poly [ADP-ribose] polymerase 1 | PARP1 |
P09874 |
1 Reference(s) |
| T03CZ8 | Catechol O-methyltransferase | COMT |
P21964 |
1 Reference(s) |
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
2 Reference(s) |
| T34I45 | Neuronal acetylcholine receptor subunit alpha-7 | CHRNA7 |
P36544 |
5 Reference(s) |
| T22H7B | Neuronal acetylcholine receptor subunit alpha-4 | CHRNA4 |
P43681 |
1 Reference(s) |
| T31JL4 | Melanocyte-stimulating hormone receptor | MC1R |
Q01726 |
2 Reference(s) |
| T25UYT | Dual specificity mitogen-activated protein kinase kinase 4 | MAP2K4 |
P45985 |
1 Reference(s) |
| T39RV3 | Dual specificity mitogen-activated protein kinase kinase 1 | MAP2K1 |
Q02750 |
1 Reference(s) |
| T75IW3 | Matrix metalloproteinase-14 | MMP14 |
P50281 |
1 Reference(s) |
| T29MD1 | Mitogen-activated protein kinase 8 | MAPK8 |
P45983 |
1 Reference(s) |
| T09GFP | Maltase-glucoamylase, intestinal [Includes: Maltase | MGAM |
O43451 |
1 Reference(s) |
| T49UAP | Ras-specific guanine nucleotide-releasing factor 1 | RASGRF1 |
Q13972 |
1 Reference(s) |
| T95IYZ | Adiponectin | ADIPOQ |
Q15848 |
1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
2 Reference(s) |
| T33JS5 | CCN family member 2 | CCN2 |
P29279 |
1 Reference(s) |
| T68SE0 | Solute carrier family 2, facilitated glucose transporter member 4 | SLC2A4 |
P14672 |
2 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
1 Reference(s) |
| T55EFK | Transcription factor E2F1 | E2F1 |
Q01094 |
1 Reference(s) |
| T45B9P | ATP-sensitive inward rectifier potassium channel 11 | KCNJ11 |
Q14654 |
1 Reference(s) |
| T64W2K | Cyclin-dependent kinase inhibitor 1 | CDKN1A |
P38936 |
1 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
3 Reference(s) |
| T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
1 Reference(s) |
| T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
2 Reference(s) |
| T07TMB | Cyclin-dependent kinase 1 | CDK1 |
P06493 |
3 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
1 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
1 Reference(s) |
| T24D36 | Transcription factor A, mitochondrial | TFAM |
Q00059 |
1 Reference(s) |
| T23XLR | Serine/threonine-protein kinase Nek11 | NEK11 |
Q8NG66 |
1 Reference(s) |
| T84ELW | Myocyte-specific enhancer factor 2A | MEF2A |
Q02078 |
1 Reference(s) |
| T82SDM | Myocyte-specific enhancer factor 2D | MEF2D |
Q14814 |
1 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
2 Reference(s) |
| T58CAO | Alpha-synuclein | SNCA |
P37840 |
1 Reference(s) |
| T42PUG | Solute carrier family 2, facilitated glucose transporter member 1 | SLC2A1 |
P11166 |
1 Reference(s) |
| T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
1 Reference(s) |
| T60DN8 | Bcl-2-like protein 11 | BCL2L11 |
O43521 |
1 Reference(s) |
| T28PHS | Angiotensin-converting enzyme | ACE |
P12821 |
1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
3 Reference(s) |
| T97FEF | Broad substrate specificity ATP-binding cassette transporter ABCG2 | ABCG2 |
Q9UNQ0 |
2 Reference(s) |
| T25S8M | Phosphatidylethanolamine N-methyltransferase | PEMT |
Q9UBM1 |
1 Reference(s) |
| T05WWN | Corticoliberin | CRH |
P06850 |
1 Reference(s) |
| T02P7Q | Dihydrofolate reductase | DHFR |
P00374 |
1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
1 Reference(s) |
| T74LFK | Neurogenic locus notch homolog protein 1 | NOTCH1 |
P46531 |
1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
1 Reference(s) |
| T62ERY | Interleukin-1 receptor-associated kinase 4 | IRAK4 |
Q9NWZ3 |
1 Reference(s) |
| T22NX4 | Toll-like receptor 2 | TLR2 |
O60603 |
1 Reference(s) |
| T76AZQ | Histidine decarboxylase | HDC |
P19113 |
1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
1 Reference(s) |
| T82G3R | Integrin beta-3 | ITGB3 |
P05106 |
1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
1 Reference(s) |
| T29GRI | Gamma-aminobutyric acid receptor subunit alpha-2 | GABRA2 |
P47869 |
1 Reference(s) |
| T63FRM | Lutropin subunit beta | LHB |
P01229 |
1 Reference(s) |
| T87C4J | Follitropin subunit beta | FSHB |
P01225 |
1 Reference(s) |
| T22Y9W | Neuropeptide S receptor | NPSR1 |
Q6W5P4 |
1 Reference(s) |
| T89L4V | Insulin | INS |
P01308 |
1 Reference(s) |
| T87N33 | Zinc finger homeobox protein 3 | ZFHX3 |
Q15911 |
1 Reference(s) |
| T23B68 | Immediate early response gene 5 protein | IER5 |
Q5VY09 |
1 Reference(s) |
| T66A7X | Activity-regulated cytoskeleton-associated protein | ARC |
Q7LC44 |
1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
2 Reference(s) |
| T73LNN | Neuropeptide S | NPS |
P0C0P6 |
1 Reference(s) |
| T37ADS | Early growth response protein 1 | EGR1 |
P18146 |
3 Reference(s) |
| T48ZIG | D(2) dopamine receptor | DRD2 |
P14416 |
1 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
1 Reference(s) |
| T92E71 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | HSD11B2 |
P80365 |
1 Reference(s) |
| T40DIM | Corticosteroid 11-beta-dehydrogenase isozyme 1 | HSD11B1 |
P28845 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
2 Reference(s) |
| T08Q1T | Amiloride-sensitive sodium channel subunit alpha | SCNN1A |
P37088 |
1 Reference(s) |
| T36PZ1 | Tryptophan 5-hydroxylase 2 | TPH2 |
Q8IWU9 |
2 Reference(s) |
| T13I7C | Transforming growth factor beta-2 proprotein | TGFB2 |
P61812 |
1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
1 Reference(s) |
| T56RMM | DNA | DNMT3A |
Q9Y6K1 |
1 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
1 Reference(s) |
| T28HOM | Leptin | LEP |
P41159 |
1 Reference(s) |
| T41BXR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | SIRT3 |
Q9NTG7 |
1 Reference(s) |
| T27J4O | Gamma-aminobutyric acid receptor subunit rho-1 | GABRR1 |
P24046 |
1 Reference(s) |
| T47G3X | Glucocorticoid receptor | NR3C1 |
P04150 |
1 Reference(s) |
| T78C6N | Cathepsin K | CTSK |
P43235 |
1 Reference(s) |
| T20P3F | Tartrate-resistant acid phosphatase type 5 | ACP5 |
P13686 |
1 Reference(s) |
| T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
2 Reference(s) |
| T80U0C | Glutathione synthetase | GSS |
P48637 |
1 Reference(s) |
| T34HYH | Interleukin-1 alpha | IL1A |
P01583 |
1 Reference(s) |
| T71BDH | Mitogen-activated protein kinase 14 | MAPK14 |
Q16539 |
1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
1 Reference(s) |
| T93W1J | Vascular endothelial growth factor C | VEGFC |
P49767 |
1 Reference(s) |
| T01QLH | Estrogen receptor | ESR1 |
P03372 |
1 Reference(s) |
| T05O6O | Estrogen receptor beta | ESR2 |
Q92731 |
1 Reference(s) |
| T25H22 | Protein kinase C beta type | PRKCB |
P05771 |
1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
| T49XOZ | Krueppel-like factor 7 | KLF7 |
O75840 |
1 Reference(s) |
| T74JJN | Fatty acid synthase | FASN |
P49327 |
1 Reference(s) |
Related Compounds (Total: 10)
C1231
Name: Chlorogenic Acid
C0333
Name: Protocatechuic Acid
C0779
Name: (1S)-1-Methyl-1,2,3,4-Tetrahydroisoquinoline-6,7-Diol
C1205
Name: Caffeine
C0442
Name: Theobromine
key description of the interaction between compound and target