Target Description
| Type | Detail |
|---|---|
| Target ID | T36PZ1 |
| Protein Name | Tryptophan 5-hydroxylase 2 |
| Uniprot ID |
Q8IWU9 |
| Protein Name Alias | EC 1.14.16.4; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2 |
| Gene ID |
121278 |
| Gene Symbol | TPH2 |
| Gene Alias | NTPH |
| TTD | T85915: Research target |
| Pfam | PF00351 |
| GO |
0009072:aromatic amino acid family metabolic process
0004510:tryptophan 5-monooxygenase activity 0042427:serotonin biosynthetic process 0051592:response to calcium ion 0043627:response to estrogen 0071285:cellular response to lithium ion 0043005:neuron projection 0014823:response to activity 0051384:response to glucocorticoid 0005829:cytosol 0031667:response to nutrient levels 0007623:circadian rhythm 0046219:indolalkylamine biosynthetic process 0005506:iron ion binding |
| PDB | 4V06 |
| Drugbank | DB00150 ; DB12095 |
| KEGG | hsa:121278 |
Related Herbs (Total: 15)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1033 | Fang Ji | 防己 | Fourstamen stephania | Stephania tetrandra |
| H0615 | Wu Zhi Mao Tao | 五指毛桃 | five-finger fig root | Ficus simplicissima |
| H0637 | Cha Ye | 茶叶 | Common tea | Camellia sinensis |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0341 | Qing Feng Teng | 青风藤 | Orientvine | Sinomenium acutum |
| H1004 | Bai Cha | 白茶 | White tea | Camellia sinensis |
| H1207 | Hu Ma | 胡麻 | white seed of oriental sesame | Sesamum indicum |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0603 | Wu Tong Ye Jin Gao | 梧桐叶浸膏 | Parasol trees | Firmiana simplex |
| H1212 | Hu Ye Gan Jin Gao | 槲叶干浸膏 | NA | Quercus dentata |
| H1181 | Hei Zhi Ma | 黑芝麻 | Oriental sesame | Sesamum indicum |
| H1029 | Fang Er Cha | 方儿茶 | khair in hindi | Senegalia catechu |
| H0087 | Ju Gu Ye | 枸骨叶 | FOLIUM iLICIS cORNUTAE | Ilex cornuta |
| H1208 | Hu Ma Ren | 胡麻仁 | white seed of oriental sesame | Sesamum indicum |