HIT-result

Target Description

Type	Detail
Target ID	T49UAP
Protein Name	Ras-specific guanine nucleotide-releasing factor 1
Uniprot ID	Q13972
Protein Name Alias	Ras-GRF1; Guanine nucleotide-releasing protein; GNRP; Ras-specific nucleotide exchange factor CDC25
Gene ID	5923
Gene Symbol	RASGRF1
Gene Alias	CDC25; GNRP; GRF1
TTD	NA
Pfam	PF00618 ; PF00621 ; PF00169 ; PF00617
GO	0000165:MAPK cascade 2000310:regulation of NMDA receptor activity 0007616:long-term memory 0035254:glutamate receptor binding 0048168:regulation of neuronal synaptic plasticity 0048167:regulation of synaptic plasticity 0005886:plasma membrane 0034976:response to endoplasmic reticulum stress 0035023:regulation of Rho protein signal transduction 0046578:regulation of Ras protein signal transduction 0043005:neuron projection 0005085:guanyl-nucleotide exchange factor activity 0031175:neuron projection development 0005829:cytosol 0035020:regulation of Rac protein signal transduction 0008283:cell population proliferation 0007165:signal transduction 0090630:activation of GTPase activity 0046579:positive regulation of Ras protein signal transduction 0043547:positive regulation of GTPase activity 0030426:growth cone 0007264:small GTPase mediated signal transduction
PDB	NA
Drugbank	NA
KEGG	hsa:5923

Type

Detail

Target ID

T49UAP

Protein Name

Ras-specific guanine nucleotide-releasing factor 1

Uniprot ID

Q13972

Protein Name Alias

Ras-GRF1; Guanine nucleotide-releasing protein; GNRP; Ras-specific nucleotide exchange factor CDC25

Gene ID

5923

Gene Symbol

RASGRF1

Gene Alias

CDC25; GNRP; GRF1

TTD

Pfam

PF00618 ; PF00621 ; PF00169 ; PF00617

0000165:MAPK cascade

2000310:regulation of NMDA receptor activity

0007616:long-term memory

0035254:glutamate receptor binding

0048168:regulation of neuronal synaptic plasticity

0048167:regulation of synaptic plasticity

0005886:plasma membrane

0034976:response to endoplasmic reticulum stress

0035023:regulation of Rho protein signal transduction

0046578:regulation of Ras protein signal transduction

0043005:neuron projection

0005085:guanyl-nucleotide exchange factor activity

0031175:neuron projection development

0005829:cytosol

0035020:regulation of Rac protein signal transduction

0008283:cell population proliferation

0007165:signal transduction

0090630:activation of GTPase activity

0046579:positive regulation of Ras protein signal transduction

0043547:positive regulation of GTPase activity

0030426:growth cone

0007264:small GTPase mediated signal transduction

PDB

Drugbank

KEGG

hsa:5923

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0603	Wu Tong Ye Jin Gao	梧桐叶浸膏	Parasol trees	Firmiana simplex
H0895	Chuan Yu Jin	川郁金	Turmeric	Curcuma longa
H1207	Hu Ma	胡麻	white seed of oriental sesame	Sesamum indicum
H1208	Hu Ma Ren	胡麻仁	white seed of oriental sesame	Sesamum indicum
H0341	Qing Feng Teng	青风藤	Orientvine	Sinomenium acutum
H0028	Jiang Huang	姜黄	Common turmeric	Curcuma longa
H1212	Hu Ye Gan Jin Gao	槲叶干浸膏	NA	Quercus dentata
H0142	Liang Jiang	良姜	NA	Alpinia officinarum
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0761	Yu Jin	郁金	AromaticTurmeric	Curcuma aromatica
H1033	Fang Ji	防己	Fourstamen stephania	Stephania tetrandra
H1240	Huang Jing Zi	黄荆子	NA	Vitex negundo
H1092	Gao Liang Jiang	高良姜	Lesser galangal	Alpinia officinarum
H0087	Ju Gu Ye	枸骨叶	FOLIUM iLICIS cORNUTAE	Ilex cornuta
H1029	Fang Er Cha	方儿茶	khair in hindi	Senegalia catechu
H0556	Tie Xian Cao	铁线草	NA	Adiantum capillus-veneris
H0615	Wu Zhi Mao Tao	五指毛桃	five-finger fig root	Ficus simplicissima
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1181	Hei Zhi Ma	黑芝麻	Oriental sesame	Sesamum indicum
H1093	Gao Liang Jiang You	高良姜油	Lesser galangal	Alpinia officinarum
H1004	Bai Cha	白茶	White tea	Camellia sinensis
H0637	Cha Ye	茶叶	Common tea	Camellia sinensis

Target Description

Related Compounds (Total: 4)

Related Herbs (Total: 22)