HIT-result

ID: C1107	Common name: ellipticine
IUPAC: 5,11-dimethyl-6H-pyrido[4,3-b]carbazole	CAS: CAS:519-23-3
Chembl ID: CHEMBL123	Pubchem ID: CID:3213
Formula: C17H14N2	TCM-ID: TCMC7543
Smiles: CC1=C2C=CN=CC2=C(C3=C1NC4=CC=CC=C43)C
Alias: Ellipticine (6CI); 5,11-Dimethyl-6H-pyrido[4,3-b]carbazole; CP 5; NSC 71795	Structure:

Target id	Protein Name	Gene Symbol	Uniprot ID	Target Level	No.of Literature Evidence
T02QBS	Cytochrome P450 1A2	CYP1A2	P05177	A	1 Reference(s)
T63BQU	Cytochrome P450 1A1	CYP1A1	P04798	A	3 Reference(s)
T57CRF	Lysozyme C	LYZ	P61626	B	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	B	1 Reference(s)
T74I49	Bcl-2-like protein 1	BCL2L1	Q07817	B	1 Reference(s)
T14LSK	E3 ubiquitin-protein ligase XIAP	XIAP	P98170	B	1 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	B	1 Reference(s)
T23P74	Caspase-9	CASP9	P55211	B	2 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	B	1 Reference(s)
T38T1U	Caspase-8	CASP8	Q14790	B	1 Reference(s)
T07TMB	Cyclin-dependent kinase 1	CDK1	P06493	C	1 Reference(s)
T24LXT	G2/mitotic-specific cyclin-B1	CCNB1	P14635	C	1 Reference(s)
T49UAP	Ras-specific guanine nucleotide-releasing factor 1	RASGRF1	Q13972	C	1 Reference(s)
T64W2K	Cyclin-dependent kinase inhibitor 1	CDKN1A	P38936	C	1 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	C	1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name

Compound Description

Related Targets (Total: 15)

Related Herbs (Total: 0)