Compound Description
| ID: C0333 | Common name: Protocatechuic Acid |
| IUPAC: 3,4-dihydroxybenzoic acid | CAS: CAS:99-50-3 |
| Chembl ID: CHEMBL37537 | Pubchem ID: CID:72 |
| Formula: C7H6O4 | TCM-ID: TCMC1956 |
| Smiles: C1=CC(=C(C=C1C(=O)O)O)O | |
| Alias:
Protocatechuic acid;
3,4-Dihydroxybenzoic acid; 1,2-Dihydroxybenzene-4-carboxylic acid; 4,5-Dihydroxybenzoic acid; 4-Carboxy-1,2-dihydroxybenzene; NSC 16631; Protocatechoic acid |
Structure:
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Related Targets (Total: 2)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
A | 1 Reference(s) |
| T09GFP | Maltase-glucoamylase, intestinal [Includes: Maltase | MGAM |
O43451 |
B | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 194)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0088 | Ju He | 橘核 | Tangerine seed | Citrus reticulata |
| H1227 | Huai Zhi | 槐枝 | NA | Sophora japonica |
| H1015 | Du Zhong | 杜仲 | Eucommia | Eucommia ulmoides |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0070 | Jing Da Ji | 京大戟 | Peking euphorbia root | Radix euphorbiae pekinensis |
| H1183 | Hong Dou | 红豆 | Hosie ormosia | Ormosia hosiei |
| H1034 | Fei Yang Cao | 飞杨草 | NA | Euphorbia hirta |
| H0395 | Sang Shen Qing Gao | 桑葚清膏 | Mulberry | Morus alba |
| H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H0874 | Chuan Long Shu Yu | 穿龙薯蓣 | Nippon yam | Dioscorea nipponica |
| H0938 | Da Suan | 大蒜 | Garlic | Allium sativum |
| H1124 | Guang Jin Qian Cao | 广金钱草 | Snowbellleaf tickclover | Desmodium styracifolium |
| H0514 | Cang Er Cao | 苍耳草 | Cocklebur grass | Xanthium sibiricum |
| H1156 | Ai Di Huang | 矮地黄 | Rehmanniae | Rehmannia glutinosa |
| H0819 | Zhi Zi Jin Gao | 栀子浸膏 | Cape jasmine fruit | Gardenia jasminoides |
| H0860 | Zong Lv Zi | 棕榈子 | NA | Trachycarpus fortunei |
| H1133 | Gui Jian Yu | 鬼箭羽 | Winged euonymus | Euonymus alatus |
| H0005 | Huo Xiang Ye | 藿香叶 | Patchouli | Pogostemon cablin |
| H0153 | Ling Zhi(1) | 灵芝 | Lucid ganoderma | Ganoderma lucidum |
| H1114 | Guan Gui | 官桂 | Cassiabarktree | Cinnamomum cassia |
| H1068 | Bai He Liu Jin Gao | 百合流浸膏 | Lily | Lilium brownii |
| H1120 | Guang Huo Xiang | 广藿香 | Patchouli | Pogostemon cablin |
| H0394 | Sang Shen Jin Gao | 桑葚浸膏 | Mulberry | Morus alba |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |
| H0773 | Chi Fu Ling | 赤茯苓 | light red indian bread | Wolfiporia cocos |
| H0109 | Ku Lian Zi | 苦楝子 | NA | Melia azedarach |
| H0315 | Pu Gong Ying Jin Gao | 蒲公英浸膏 | Mongolian dandelion | Taraxacum mongolicum |
| H0056 | Jin Qiao Mai | 金荞麦 | Wild buckwheat rhizome | Rhizoma fagopyri cymosi |
| H0716 | Yang Cong | 洋葱 | Common onion | Allium cepa |
| H0509 | Cang Er | 苍耳 | Siberian cocklebur | Xanthium sibiricum |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0214 | Bei He Huan | 北合欢 | Albizia | Albizia julibrissin |
| H0892 | Chuan Xiong | 川芎 | cnidium officinale | Cnidium officinale |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H1010 | Du Huo Xiang | 杜藿香 | Patchouli | Pogostemon cablin |
| H1019 | E Bu Shi Cao | 鹅不食草 | Small centipeda | Centipeda minima |
| H0857 | Zong Ban Tan | 棕板炭 | NA | Trachycarpus fortunei |
| H0179 | Lu Xian Cao | 鹿衔草 | Chinese pyrola | Pyrola calliantha |
| H0856 | Zong Ban | 棕板 | NA | Trachycarpus fortunei |
| H1073 | Gan Cao Jie | 甘草节 | Glycyrrhiza uralensis fisch | Glycyrrhiza uralensis |
| H1087 | Gan Sui | 甘遂 | Kansui euphorbia | Euphorbia kansui |
| H0015 | Ji Xing Zi | 急性子 | Garden balsam seed | Impatiens balsamina |
| H0731 | Ye Mei Gui Guo | 野玫瑰果 | Rosehips | Rosa canina |
| H1127 | Guang Shan Zha | 广山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0825 | Zhu Fu Shen | 朱茯神 | Indian bread with pine | Poria cocos |
| H0016 | Ji Xue Cao | 积雪草 | Asiatic pennywort | Centella asiatica |
| H1184 | Bai Lian | 白蔹 | Japanese ampelopsis | Ampelopsis japonica |
| H1201 | Hu Er Cao | 虎耳草 | Creeping rockfoil | Saxifraga stolonifera |
| H0421 | Shan Zha Qing Gao | 山楂清膏 | Chinese hawthorn | Crataegus pinnatifida |
| H1150 | Hai Jin Sha Teng Gan Jin Gao | 海金沙藤干浸膏 | NA | Lygodium japonicum |
| H0663 | Xiao Ji | 小蓟 | Setose thistle | Cirsium setosum |
| H0740 | Yi Zhi | 益智 | Fructus alpinae oxyphyllae | Alpinia oxyphylla |
| H0155 | Ban Xia | 半夏 | Ternate pinellia | Pinellia ternata |
| H1051 | Bai Guo | 白果 | Ginkgo nut | Ginkgo biloba |
| H1061 | Bai He | 百合 | Lily | Lilium brownii |
| H0240 | Mi Gan Cao | 蜜甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0632 | Xia Ku Cao | 夏枯草 | Common selfheal | Prunella vulgaris |
| H0108 | Ku Lian Pi | 苦楝皮 | Chinaberry-tree bark | Melia azedarach |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H0314 | Pu Gong Ying | 蒲公英 | Mongolian dandelion | Taraxacum mongolicum |
| H1118 | Bai Ji | 白芨 | Common bletilla | Bletilla striata |
| H0519 | Suo Yang | 锁阳 | Songaria cynomorium | Cynomorium songaricum |
| H1147 | Hai Jin Sha | 海金砂 | Japanese climbing fern | Lygodium japonicum |
| H0973 | Di Huang Tan | 地黄炭 | Rehmanniae | Rehmannia glutinosa |
| H1102 | Gu Sui Bu | 骨碎补 | Fortune’s drynaria rhizome | Drynaria fortunei |
| H0571 | Tu Gan Cao | 土甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1140 | Guo Gang Long | 过岗龙 | NA | Entada phaseoloides |
| H0409 | Shan Jiang | 山姜 | shell ginger | Alpinia zerumbet |
| H0615 | Wu Zhi Mao Tao | 五指毛桃 | five-finger fig root | Ficus simplicissima |
| H1222 | Huai Hua | 槐花 | flower bud of japanese pagodatree | Sophora japonica |
| H1075 | Gan Cao Liu Jin Gao | 甘草流浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1072 | Gan Cao Gao | 甘草膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1224 | Huai Jiao | 槐角 | pod of japanese pagodatree | Sophora japonica |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H1046 | Feng Xian Tou Gu Cao | 凤仙透骨草 | Spotted snapweed | Impatiens balsamina |
| H0419 | Shan Zha | 山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H0606 | Wu Wei Zi Chun Jin Gao | 五味子醇浸膏 | Five-flavor berry | Schisandra chinensis |
| H0858 | Zong Lv Pi | 棕榈皮 | Fortune windmillpalm | Trachycarpus fortunei |
| H0818 | Zhi Zi | 栀子 | Cape jasmine fruit | Gardenia jasminoides |
| H1079 | Gan Di Huang | 干地黄 | Adhesive rehmannia dried root | Rehmannia glutinosa |
| H0967 | Di Er Cao | 地耳草 | Japanese stJohn’swort | Hypericum japonicum |
| H0717 | Yang Cong Tou | 洋葱头 | Common onion | Allium cepa |
| H0166 | Long Kui | 龙葵 | Black nightshade | Solanum nigrum |
| H0085 | Jiu Yu Rou | 酒萸肉 | Asiatic cornelian cherry | Cornus officinalis |
| H0608 | Wu Wei Zi Jin Gao | 五味子浸膏 | Five-flavor berry | Schisandra chinensis |
| H1100 | Gu Jing Cao | 谷精草 | Pipewart | Eriocaulon buergerianum |
| H0486 | Shui Hong Hua Ye | 水红花叶 | Fructus polygoni orientalis | Polygonum orientale |
| H0733 | Ye Shan Zha | 野山楂 | nippon bawthorn | Crataegus pinnatifida |
| H0120 | Ban Bian Qi | 半边旗 | pinnated brake herb | Pteris semipinnata |
| H0327 | Qian Li Guang | 千里光 | Climbing groundsel | Senecio scandens |
| H0048 | Ai Tan | 艾炭 | Blumea camphor | Blumea balsamifera |
| H1244 | Huang Miao | 黄苗 | NA | Taraxacum mongolicum |
| H0934 | Da Ji | 大戟 | Peking spurge root | Radix euphorbiae pekinensis |
| H0743 | Yi Zhi Ren | 益智仁 | Sharpleaf galangal | Alpinia oxyphylla |
| H0893 | Chuan Xiong Jin Gao | 川芎浸膏 | cnidium officinale | Cnidium officinale |
| H0612 | Cao Shan Hu Jin Gao | 草珊瑚浸膏 | NA | Sarcandra glabra |
| H1186 | Hong Gen Cao | 红根草 | Hispid sage | Salvia prionitis |
| H0939 | Da Xue Teng | 大血藤 | Sargentgloryvine | Sargentodoxa cuneata |
| H0004 | Huo Xiang | 藿香 | Patchouli | Pogostemon cablin |
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H1016 | Du Zhong Tan | 杜仲炭 | Eucommia | Eucommia ulmoides |
| H1066 | Gan Cao | 甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1067 | Gan Cao Fen | 甘草粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1053 | Fu Ling | 茯苓 | Indian bread | Wolfiporia cocos |
| H0159 | Ban Xia Qu | 半夏曲 | Pinellia tuber leaven | Pinellia ternata |
| H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0001 | Ai Pian | 艾片 | Blumea camphor | Blumea balsamifera |
| H0424 | Shan Zhi | 山栀 | Cape jasmine | Gardenia jasminoides |
| H0173 | Lu Hui | 芦荟 | Kulaso aloe dried juice | Aloe vera |
| H0065 | Jin Yin Hua Ti Qu Ye | 金银花提取液 | Japanese honeysuckle | Lonicera japonica |
| H0365 | Rou Dou Kou | 肉豆蔻 | Common nutmeg | Myristica fragrans |
| H1017 | Du Zhong Ye | 杜仲叶 | Eucommia leaf | Eucommia ulmoides |
| H0241 | Mi Hou Tao | 猕猴桃 | Yangtao actinidia | Actinidia chinensis |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0368 | Rou Gui Zi | 肉桂子 | Cassiabarktree | Cinnamomum cassia |
| H0605 | Wu Wei Zi | 五味子 | Chinese magnoliavine | Schisandra chinensis |
| H0995 | Dong Chong Xia Cao | 冬虫夏草 | Aweto | Cordyceps sinensis |
| H0227 | Mang Guo Ye | 芒果叶 | Mango leaf | Mangifera indica |
| H0007 | Huo Xue Teng | 活血藤 | NA | Sargentodoxa cuneata |
| H0534 | Teng Li Gen | 藤梨根 | NA | Actinidia arguta |
| H0923 | Da Feng Ai | 大风艾 | Ngai camphor | Blumea balsamifera |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0468 | Shi Wei | 石韦 | Japanese felt fern frond | Pyrrosia lingua |
| H1148 | Hai Jin Sha Cao | 海金沙草 | NA | Lygodium japonicum |
| H0572 | Tu Huo Xiang | 土藿香 | Patchouli | Pogostemon cablin |
| H1045 | Feng Xian Hua | 凤仙花 | Spotted snapweed | Impatiens balsamina |
| H1090 | Gao Ben | 藁本 | Chinese ligusticum | Ligusticum sinense |
| H0354 | Ren Dong Teng | 忍冬藤 | Japanese honeysuckle vine | Lonicera japonica |
| H0064 | Jin Yin Hua | 金银花 | Japanese honeysuckle | Lonicera japonica |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H0897 | Chuan Lian | 川楝 | Chinaberry | Melia azedarach |
| H0396 | Sang Ye | 桑叶 | White mulberry leaf | Morus alba |
| H0093 | Ju Pi | 橘皮 | Tangerine pericarp | Citrus reticulata |
| H0391 | Sang Pi | 桑皮 | Prepared root-bark white mulberry | Morus alba |
| H0075 | Jing Mi | 粳米 | Rice | Oryza sativa |
| H1074 | Gan Cao Jin Gao | 甘草浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0164 | Ban Zhi Lian | 半枝莲 | Barbed skullcap | Scutellaria barbata |
| H0397 | Sang Zhi | 桑枝 | White mulberry branch | Morus alba |
| H1070 | Gan Cao Gan Gao Fen | 甘草干膏粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0750 | Yin Xing Ye | 银杏叶 | Folium ginkgo | Ginkgo biloba |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H0718 | Yang Jiao Qi | 羊角七 | NA | Bletilla striata |
| H0473 | Shu Di Huang | 熟地黄 | Adhesive rehmannia cocked root | Rehmannia glutinosa |
| H0057 | Jin Sha Teng | 金沙藤 | NA | Lygodium japonicum |
| H0219 | Man Shan Hong | 满山红 | Dahurian rhododendron | Rhododendron dauricum |
| H0393 | Sang Shen | 桑葚 | Mulberry | Morus alba |
| H1220 | Hua Xiang Shu Guo | 化香树果 | NA | Platycarya strobilacea |
| H0422 | Shan Zha Tan | 山楂炭 | Chinese hawthorn | Crataegus pinnatifida |
| H1213 | Hu Zhang | 虎杖 | Japanese fleeceflower | Polygonum cuspidatum |
| H1225 | Huai Mi | 槐米 | NA | Sophora japonica |
| H0128 | Lao Guan Cao | 老鹳草 | Wilford cranesbill | Geranium wilfordii |
| H0420 | Shan Zha Chou Gao | 山楂稠膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0338 | Qing Ban Xia | 清半夏 | Ternate pinellia | Pinellia ternata |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0485 | Shui Hong Hua | 水红花 | Fructus polygoni orientalis | Polygonum orientale |
| H0053 | Jin Lian Hua | 金莲花 | Chinese globeflower | Trollius chinensis |
| H0607 | Wu Wei Zi Jin Chu Wu | 五味子浸出物 | Five-flavor berry | Schisandra chinensis |
| H1212 | Hu Ye Gan Jin Gao | 槲叶干浸膏 | NA | Quercus dentata |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H1069 | Gan Cao Gan Gao | 甘草干膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0932 | Ba Qia | 菝葜 | Chinaroot greenbrier | Smilax china |
| H0496 | Shui Ze Lan | 水泽兰 | NA | Lycopus lucidus |
| H0570 | Tu Fu Ling | 土茯苓 | Glabrous greenbrier | Smilax glabra |
| H0609 | Wu Wei Zi Liu Jin Gao | 五味子流浸膏 | Five-flavor berry | Schisandra chinensis |
| H0366 | Rou Gui | 肉桂 | Cassiabarktree | Cinnamomum cassia |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
| H0299 | Niu Zhi | 牛至 | wild marjoram | Origanum vulgare |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H1141 | Guo Gang Long Jin Gao | 过岗龙浸膏 | NA | Entada phaseoloides |
| H0700 | Ya Zhi Cao | 鸭跖草 | Common dayflower | Commelina communis |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H1071 | Gan Cao Gan Jin Gao | 甘草干浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0439 | Sheng Ban Xia | 生半夏 | Ternate pinellia | Pinellia ternata |
| H1149 | Hai Jin Sha Teng | 海金沙藤 | NA | Lygodium japonicum |
| H1221 | Hua Xiang Shu Guo Xu | 化香树果序 | NA | Platycarya strobilacea |
| H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0457 | Shi Er | 石耳 | Rock-Ears | Umbilicaria esculenta |
| H1020 | E Bu Shi Cao Nong Suo Ye | 鹅不食草浓缩液 | Small centipeda | Centipeda minima |
| H0972 | Di Huang | 地黄 | Rehmanniae | Rehmannia glutinosa |
| H0427 | Shan Zhu Yu | 山茱萸 | Asiatic cornelian cherry | Cornus officinalis |
| H1055 | Bai Guo Ren | 白果仁 | ginkgo | Ginkgo biloba |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H1018 | Bai Dou Kou | 白豆蔻 | Round cardamom | Amomum kravanh |
| H0083 | Jiu Jie Cha | 九节茶 | Glabrous sarcandra | Sarcandra glabra |
| H1139 | Gui Zhi | 桂枝 | Cassiabarktree twig | Cinnamomum cassia |
| H0762 | Yu Li Ren | 郁李仁 | NA | Prunus japonica |
| H0152 | Ling Zhi Jin Gao | 灵芝浸膏 | NA | Ganoderma lucidum |
| H0237 | Mei Gui Hua | 玫瑰花 | Rugose rose flower | Rosa rugosa |
| H0444 | Sheng Gan Cao | 生甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
Ckey description of the interaction between compound and target