| Herb ID: H1148 | Chinese Character: 海金沙草 | 
| English Name: NA | Latin Name: Lygodium japonicum | 
| Chinese Pin Yin : Hai Jin Sha Cao | TCM-ID: TCMH781 | 
| Therapeutic Function in Chinese : NA | Therapeutic Function in English: NA | 
| Herb Function: NA | |
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence | 
|---|---|---|---|---|
| T22NX4 | Toll-like receptor 2 | TLR2 | 
                                O60603 | 
                            1 Reference(s) | 
| T76QBQ | CREB-regulated transcription coactivator 2 | CRTC2 | 
                                Q53ET0 | 
                            1 Reference(s) | 
| T30VNV | Myeloperoxidase | MPO | 
                                P05164 | 
                            1 Reference(s) | 
| T62P0D | Collagenase 3 | MMP13 | 
                                P45452 | 
                            1 Reference(s) | 
| T09H2Z | Nitric oxide synthase, inducible | NOS2 | 
                                P35228 | 
                            2 Reference(s) | 
| T74WWP | Peroxisome proliferator-activated receptor delta | PPARD | 
                                Q03181 | 
                            1 Reference(s) | 
| T14JSX | Plasminogen | PLG | 
                                P00747 | 
                            1 Reference(s) | 
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA | 
                                Q07869 | 
                            3 Reference(s) | 
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG | 
                                P37231 | 
                            1 Reference(s) | 
| T67LRH | RNA-binding protein Musashi homolog 1 | MSI1 | 
                                O43347 | 
                            1 Reference(s) | 
| T13KGH | Tyrosinase | TYR | 
                                P14679 | 
                            1 Reference(s) | 
| T04H8Y | Beta-secretase 1 | BACE1 | 
                                P56817 | 
                            1 Reference(s) | 
| T58XLK | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 | 
                                P18031 | 
                            1 Reference(s) | 
| T26EZU | Myc proto-oncogene protein | MYC | 
                                P01106 | 
                            1 Reference(s) | 
| T37G49 | Platelet-activating factor acetylhydrolase | PLA2G7 | 
                                Q13093 | 
                            1 Reference(s) | 
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 | 
                                P28482 | 
                            1 Reference(s) | 
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 | 
                                P31749 | 
                            1 Reference(s) | 
| T39YFG | Trypsin-1 | PRSS1 | 
                                P07477 | 
                            1 Reference(s) | 
| T54WR0 | Fatty acid-binding protein 5 | FABP5 | 
                                Q01469 | 
                            1 Reference(s) | 
| T21Q0D | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | 
                                P04035 | 
                            1 Reference(s) | 
| T12T4H | Brain-derived neurotrophic factor | BDNF | 
                                P23560 | 
                            1 Reference(s) | 
| T07S0E | BDNF/NT-3 growth factors receptor | NTRK2 | 
                                Q16620 | 
                            1 Reference(s) | 
| T90XYZ | C-reactive protein | CRP | 
                                P02741 | 
                            1 Reference(s) | 
| T51WGR | Pancreas/duodenum homeobox protein 1 | PDX1 | 
                                P52945 | 
                            1 Reference(s) | 
| T43NBB | Solute carrier family 2, facilitated glucose transporter member 2 | SLC2A2 | 
                                P11168 | 
                            1 Reference(s) | 
| T89L4V | Insulin | INS | 
                                P01308 | 
                            1 Reference(s) | 
| T38WWN | Serum paraoxonase/arylesterase 1 | PON1 | 
                                P27169 | 
                            1 Reference(s) | 
| T23YZF | Peptidyl-glycine alpha-amidating monooxygenase | PAM | 
                                P19021 | 
                            1 Reference(s) | 
| T77FOL | Neuromodulin | GAP43 | 
                                P17677 | 
                            1 Reference(s) | 
| T93VFT | Endothelin-1 | EDN1 | 
                                P05305 | 
                            1 Reference(s) | 
| T36SOV | Plasminogen activator inhibitor 1 | SERPINE1 | 
                                P05121 | 
                            1 Reference(s) | 
| T02DEN | Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide | GCG | 
                                P01275 | 
                            1 Reference(s) | 
| T48UT8 | Cholesteryl ester transfer protein | CETP | 
                                P11597 | 
                            1 Reference(s) | 
| T32HPO | Aspartyl aminopeptidase | DNPEP | 
                                Q9ULA0 | 
                            1 Reference(s) | 
| T20H9F | Stromelysin-1 | MMP3 | 
                                P08254 | 
                            1 Reference(s) | 
| T02YLA | Alpha-lactalbumin | LALBA | 
                                P00709 | 
                            1 Reference(s) | 
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 | 
                                P29474 | 
                            1 Reference(s) | 
| T76TED | Pro-opiomelanocortin | POMC | 
                                P01189 | 
                            1 Reference(s) | 
| T37JN5 | Neutrophil gelatinase-associated lipocalin | LCN2 | 
                                P80188 | 
                            1 Reference(s) | 
| T17UP9 | C-C motif chemokine 2 | CCL2 | 
                                P13500 | 
                            1 Reference(s) | 
| T09GFP | Maltase-glucoamylase, intestinal [Includes: Maltase | MGAM | 
                                O43451 | 
                            1 Reference(s) | 
| T69NG6 | Interleukin-10 | IL10 | 
                                P22301 | 
                            1 Reference(s) | 
| T23VMI | Tumor necrosis factor | TNF | 
                                P01375 | 
                            1 Reference(s) | 
| T51EKP | Apolipoprotein M | APOM | 
                                O95445 | 
                            1 Reference(s) | 
| T07VV7 | Guanylin | GUCA2A | 
                                Q02747 | 
                            1 Reference(s) | 
| T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN | 
                                P60484 | 
                            1 Reference(s) | 
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 | 
                                P10415 | 
                            4 Reference(s) | 
| T80WPU | Protein ABHD15 | ABHD15 | 
                                Q6UXT9 | 
                            1 Reference(s) | 
| T56OUM | 14-3-3 protein zeta/delta | YWHAZ | 
                                P63104 | 
                            1 Reference(s) | 
| T24YWQ | Insulin-degrading enzyme | IDE | 
                                P14735 | 
                            1 Reference(s) | 
| T34HYH | Interleukin-1 alpha | IL1A | 
                                P01583 | 
                            1 Reference(s) | 
| T67RBZ | Mitochondrial uncoupling protein 2 | UCP2 | 
                                P55851 | 
                            1 Reference(s) | 
| T67HYX | Mitochondrial uncoupling protein 3 | UCP3 | 
                                P55916 | 
                            1 Reference(s) | 
| T19EKF | Cholecystokinin | CCK | 
                                P06307 | 
                            1 Reference(s) | 
| T19XSL | Fatty acid-binding protein, liver | FABP1 | 
                                P07148 | 
                            1 Reference(s) | 
| T23APZ | Retinol-binding protein 2 | RBP2 | 
                                P50120 | 
                            1 Reference(s) | 
| T38K2W | Receptor tyrosine-protein kinase erbB-2 | ERBB2 | 
                                P04626 | 
                            1 Reference(s) | 
| T03NWF | Sterol O-acyltransferase 1 | SOAT1 | 
                                P35610 | 
                            1 Reference(s) | 
| T48YPL | Aquaporin-3 | AQP3 | 
                                Q92482 | 
                            1 Reference(s) | 
| T53SLQ | Aquaporin-9 | AQP9 | 
                                O43315 | 
                            1 Reference(s) | 
| T75EH8 | Glucagon-like peptide 1 receptor | GLP1R | 
                                P43220 | 
                            1 Reference(s) | 
| T52VL6 | Signal transducer and activator of transcription 5A | STAT5A | 
                                P42229 | 
                            1 Reference(s) | 
| T19K8W | Signal transducer and activator of transcription 5B | STAT5B | 
                                P51692 | 
                            1 Reference(s) | 
| T82I7J | C-C motif chemokine 16 | CCL16 | 
                                O15467 | 
                            1 Reference(s) | 
| T49TDM | Matrix metalloproteinase-9 | MMP9 | 
                                P14780 | 
                            1 Reference(s) | 
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 | 
                                P05362 | 
                            1 Reference(s) | 
| T98DNG | Natriuretic peptides A | NPPA | 
                                P01160 | 
                            1 Reference(s) | 
| T78ILO | Stearoyl-CoA desaturase | SCD | 
                                O00767 | 
                            1 Reference(s) | 
| T63GUB | Proto-oncogene c-Fos | FOS | 
                                P01100 | 
                            1 Reference(s) | 
| T68IZC | Natriuretic peptides B | NPPB | 
                                P16860 | 
                            1 Reference(s) | 
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 | 
                                P19838 | 
                            2 Reference(s) | 
| T26KIE | Transcription factor AP-1 | JUN | 
                                P05412 | 
                            1 Reference(s) | 
| T02H9U | Nuclear factor of activated T-cells, cytoplasmic 4 | NFATC4 | 
                                Q14934 | 
                            1 Reference(s) | 
| T80TUC | Apoptosis regulator BAX | BAX | 
                                Q07812 | 
                            1 Reference(s) |