Compound Description
| ID: C0263 | Common name: Oleic Acid |
| IUPAC: (Z)-octadec-9-enoic acid | CAS: CAS:112-80-1 |
| Chembl ID: CHEMBL8659 | Pubchem ID: CID:445639 |
| Formula: C18H34O2 | TCM-ID: TCMC1788 |
| Smiles: CCCCCCCCC=CCCCCCCCC(=O)O | |
| Alias:
9-Octadecenoic acid (Z)-;
Oleic acid; (9Z)-9-Octadecenoic acid; 9-Octadecenoic acid, (Z)-; 9-cis-Octadecenoic acid; 9Z-Octadecenoic acid; B 115; C18 |
Structure:
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Related Targets (Total: 40)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T30VNV | Myeloperoxidase | MPO |
P05164 |
A | 1 Reference(s) |
| T62P0D | Collagenase 3 | MMP13 |
P45452 |
A | 1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
A | 2 Reference(s) |
| T74WWP | Peroxisome proliferator-activated receptor delta | PPARD |
Q03181 |
A | 1 Reference(s) |
| T14JSX | Plasminogen | PLG |
P00747 |
A | 1 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
A | 2 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
A | 1 Reference(s) |
| T67LRH | RNA-binding protein Musashi homolog 1 | MSI1 |
O43347 |
A | 1 Reference(s) |
| T39YFG | Trypsin-1 | PRSS1 |
P07477 |
B | 1 Reference(s) |
| T54WR0 | Fatty acid-binding protein 5 | FABP5 |
Q01469 |
B | 1 Reference(s) |
| T21Q0D | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR |
P04035 |
B | 1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
B | 1 Reference(s) |
| T07S0E | BDNF/NT-3 growth factors receptor | NTRK2 |
Q16620 |
B | 1 Reference(s) |
| T90XYZ | C-reactive protein | CRP |
P02741 |
B | 1 Reference(s) |
| T51WGR | Pancreas/duodenum homeobox protein 1 | PDX1 |
P52945 |
B | 1 Reference(s) |
| T43NBB | Solute carrier family 2, facilitated glucose transporter member 2 | SLC2A2 |
P11168 |
B | 1 Reference(s) |
| T89L4V | Insulin | INS |
P01308 |
B | 1 Reference(s) |
| T38WWN | Serum paraoxonase/arylesterase 1 | PON1 |
P27169 |
B | 1 Reference(s) |
| T23YZF | Peptidyl-glycine alpha-amidating monooxygenase | PAM |
P19021 |
B | 1 Reference(s) |
| T77FOL | Neuromodulin | GAP43 |
P17677 |
B | 1 Reference(s) |
| T93VFT | Endothelin-1 | EDN1 |
P05305 |
B | 1 Reference(s) |
| T36SOV | Plasminogen activator inhibitor 1 | SERPINE1 |
P05121 |
B | 1 Reference(s) |
| T02DEN | Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide | GCG |
P01275 |
B | 1 Reference(s) |
| T48UT8 | Cholesteryl ester transfer protein | CETP |
P11597 |
B | 1 Reference(s) |
| T32HPO | Aspartyl aminopeptidase | DNPEP |
Q9ULA0 |
B | 1 Reference(s) |
| T20H9F | Stromelysin-1 | MMP3 |
P08254 |
B | 1 Reference(s) |
| T02YLA | Alpha-lactalbumin | LALBA |
P00709 |
B | 1 Reference(s) |
| T67RBZ | Mitochondrial uncoupling protein 2 | UCP2 |
P55851 |
C | 1 Reference(s) |
| T67HYX | Mitochondrial uncoupling protein 3 | UCP3 |
P55916 |
C | 1 Reference(s) |
| T19EKF | Cholecystokinin | CCK |
P06307 |
C | 1 Reference(s) |
| T19XSL | Fatty acid-binding protein, liver | FABP1 |
P07148 |
C | 1 Reference(s) |
| T23APZ | Retinol-binding protein 2 | RBP2 |
P50120 |
C | 1 Reference(s) |
| T38K2W | Receptor tyrosine-protein kinase erbB-2 | ERBB2 |
P04626 |
C | 1 Reference(s) |
| T03NWF | Sterol O-acyltransferase 1 | SOAT1 |
P35610 |
C | 1 Reference(s) |
| T48YPL | Aquaporin-3 | AQP3 |
Q92482 |
C | 1 Reference(s) |
| T53SLQ | Aquaporin-9 | AQP9 |
O43315 |
C | 1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
C | 1 Reference(s) |
| T75EH8 | Glucagon-like peptide 1 receptor | GLP1R |
P43220 |
C | 1 Reference(s) |
| T52VL6 | Signal transducer and activator of transcription 5A | STAT5A |
P42229 |
C | 1 Reference(s) |
| T19K8W | Signal transducer and activator of transcription 5B | STAT5B |
P51692 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 166)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0888 | Ba Dou Ye | 巴豆叶 | Pu rging croton | Croton tiglium |
| H0720 | Yang Jin Hua | 洋金花 | Hindu datura flower | Datura metel |
| H0580 | Tu Si Rou | 菟丝肉 | Dodder seed | Cuscuta australis |
| H0088 | Ju He | 橘核 | Tangerine seed | Citrus reticulata |
| H0054 | Jin Niu Cao | 金牛草 | NA | Polygala glomerata |
| H1128 | Bai Jiang | 败酱 | Whiteflower patrinia | Patrinia villosa |
| H1254 | Huang Qin Tan | 黄芩炭 | Extract of root of Baikal skullcaap | Scutellaria baicalensis |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0581 | Tu Si Zi | 菟丝子 | Dodder seed | Cuscuta australis |
| H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H0524 | Tan Xiang | 檀香 | Sandalwood | Santalum album |
| H1156 | Ai Di Huang | 矮地黄 | Rehmanniae | Rehmannia glutinosa |
| H0576 | Tu Mu Xiang | 土木香 | Elecampane inula | Inula helenium |
| H0005 | Huo Xiang Ye | 藿香叶 | Patchouli | Pogostemon cablin |
| H0697 | Ya Ma Zi | 亚麻子 | Common flax seed | Linum usitatissimum |
| H0126 | Lai Fu Zi | 莱菔子 | Garden radish seed | Raphanus sativus |
| H0153 | Ling Zhi(1) | 灵芝 | Lucid ganoderma | Ganoderma lucidum |
| H1251 | Huang Qin | 黄芩 | Root of Baikal skullcaap | Scutellaria baicalensis |
| H1120 | Guang Huo Xiang | 广藿香 | Patchouli | Pogostemon cablin |
| H0310 | Pian Qin | 片芩 | Scutellaria amoena | Scutellaria baicalensis |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |
| H0109 | Ku Lian Zi | 苦楝子 | NA | Melia azedarach |
| H0383 | San Qi Jing Ye | 三七茎叶 | Sanchi | Panax notoginseng |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0551 | Cang Zhu | 苍术 | Swordlike atractylodes | Atractylodes lancea |
| H0224 | Man Tuo Luo Ye | 曼陀罗叶 | Hindu datura leaf | Datura metel |
| H0071 | Bai Ye | 柏叶 | Chinese arborvitae twig | Platycladus orientalis |
| H0892 | Chuan Xiong | 川芎 | cnidium officinale | Cnidium officinale |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H1010 | Du Huo Xiang | 杜藿香 | Patchouli | Pogostemon cablin |
| H0079 | Jiu Cai | 韭菜 | Tuber onion | Allium tuberosum |
| H0739 | Yi Yi Ren | 薏苡仁 | Jobstears seed | Coix lacryma- jobi var. ma - yuen |
| H0583 | Tu Si Zi Teng | 菟丝子藤 | Dodder seed | Cuscuta australis |
| H0530 | Tao Ren Shuang | 桃仁霜 | Peach kernel | Prunus persica |
| H0740 | Yi Zhi | 益智 | Fructus alpinae oxyphyllae | Alpinia oxyphylla |
| H0016 | Ji Xue Cao | 积雪草 | Asiatic pennywort | Centella asiatica |
| H1150 | Hai Jin Sha Teng Gan Jin Gao | 海金沙藤干浸膏 | NA | Lygodium japonicum |
| H0466 | Cai Fu Zi | 菜菔子 | Semen raphani | Raphanus sativus |
| H1051 | Bai Guo | 白果 | Ginkgo nut | Ginkgo biloba |
| H0108 | Ku Lian Pi | 苦楝皮 | Chinaberry-tree bark | Melia azedarach |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0853 | Zi Wan | 紫菀 | Tatarion aster | Aster tataricus |
| H0300 | Nv Zhen Zi | 女贞子 | Glossy privet fruit | Ligustrum lucidum |
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H0704 | Yan Guan Huang Bai | 盐关黄柏 | Amur cork tree | Phellodendron amurense |
| H0878 | Ba Dou Shuang | 巴豆霜 | Defatted croton seed powder | Croton tiglium |
| H0195 | Ma Chi Xian | 马齿苋 | Purslane | Portulaca oleracea |
| H0519 | Suo Yang | 锁阳 | Songaria cynomorium | Cynomorium songaricum |
| H1147 | Hai Jin Sha | 海金砂 | Japanese climbing fern | Lygodium japonicum |
| H0225 | Man Tuo Luo Zi | 曼陀罗子 | Hindu datura seed | Datura metel |
| H0104 | Bai Zhu | 白术 | Largehead atractylodes | Atractylodes macrocephala |
| H0973 | Di Huang Tan | 地黄炭 | Rehmanniae | Rehmannia glutinosa |
| H0409 | Shan Jiang | 山姜 | shell ginger | Alpinia zerumbet |
| H0531 | Tao Zhi | 桃枝 | Peach juvenile branch | Prunus persica |
| H0003 | Huo Ma Ren | 火麻仁 | Hemp fimble seed | Cannabis sativa |
| H0134 | Li Zhi He | 荔枝核 | Lychee seed | Litchi chinensis |
| H0816 | Chu Ling Dan | 臭灵丹 | laggera pterodonta | Laggera pterodonta |
| H1176 | Hei Hu Jiao | 黑胡椒 | Black pepper | Piper nigrum |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H0384 | San Qi Ye | 三七叶 | Folium panax notoginseng | Panax notoginseng |
| H0844 | Zi Cao | 紫草 | Redroot gromwell | Lithospermum erythrorhizon |
| H0527 | Tao | 桃 | Peach | Prunus persica |
| H0060 | Jin Si Ku Lian | 金丝苦楝 | NA | Cardiospermum halicacabum |
| H1079 | Gan Di Huang | 干地黄 | Adhesive rehmannia dried root | Rehmannia glutinosa |
| H1130 | Guang Zao | 广枣 | fruit of axillary choerospondias | Fructus choerospondiatis |
| H1170 | He Zi | 诃子 | Medicine terminalia | Terminalia chebula |
| H0381 | San Qi Gao Fen | 三七膏粉 | Sanchi | Panax notoginseng |
| H1208 | Hu Ma Ren | 胡麻仁 | white seed of oriental sesame | Sesamum indicum |
| H0327 | Qian Li Guang | 千里光 | Climbing groundsel | Senecio scandens |
| H0771 | Yuan Zhi Liu Jin Gao | 远志流浸膏 | Thinleaf milkwort | Polygala tenuifolia |
| H1097 | Gong Ding Xiang | 公丁香 | NA | Syzygium aromaticum |
| H1252 | Huang Qin Jin Gao | 黄芩浸膏 | Extract of root of Baikal skullcaap | Scutellaria baicalensis |
| H0743 | Yi Zhi Ren | 益智仁 | Sharpleaf galangal | Alpinia oxyphylla |
| H0893 | Chuan Xiong Jin Gao | 川芎浸膏 | cnidium officinale | Cnidium officinale |
| H0004 | Huo Xiang | 藿香 | Patchouli | Pogostemon cablin |
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H1230 | Huang Bai Fen | 黄柏粉 | Amur corktree | Phellodendron amurense |
| H0714 | Yan Tai Chai Hu | 烟台柴胡 | Chinese thorowax | Bupleurum chinense |
| H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0461 | Shi Jun Zi Ren | 使君子仁 | NA | Combretum indicum |
| H0604 | Wu Wei Teng | 五味藤 | NA | Securidaca inappendiculata |
| H0173 | Lu Hui | 芦荟 | Kulaso aloe dried juice | Aloe vera |
| H0385 | San Qi Ye Jing | 三七叶茎 | Sanchi | Panax notoginseng |
| H0650 | Chai Hu | 柴胡 | Chinese thorowax | Bupleurum chinense |
| H0365 | Rou Dou Kou | 肉豆蔻 | Common nutmeg | Myristica fragrans |
| H0659 | Chai Hu Jin Gao | 柴胡浸膏 | Chinese thorowax | Bupleurum chinense |
| H1188 | Hong Hua | 红花 | Safflower | Carthamus tinctorius |
| H1214 | Hua Jiao | 花椒 | Bunge pricklyash | Zanthoxylum bungeanum |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0227 | Mang Guo Ye | 芒果叶 | Mango leaf | Mangifera indica |
| H0382 | San Qi Hua | 三七花 | Sanchi | Panax notoginseng |
| H0002 | Hui Xiang | 茴香 | Fennel fruit | Foeniculum vulgare |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
| H1229 | Bai Mu Xiang | 白木香 | Chinese eaglewood | Aquilaria sinensis |
| H1131 | Gui Ban | 龟板 | Tortoise plastron | Plastrum testudinis |
| H1223 | Huai Hun Cao | 还魂草 | NA | Aster tataricus |
| H0895 | Chuan Yu Jin | 川郁金 | Turmeric | Curcuma longa |
| H1148 | Hai Jin Sha Cao | 海金沙草 | NA | Lygodium japonicum |
| H0572 | Tu Huo Xiang | 土藿香 | Patchouli | Pogostemon cablin |
| H1253 | Huang Qin Jin Gao Fen | 黄芩浸膏粉 | Extract of root of Baikal skullcaap | Scutellaria baicalensis |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H0897 | Chuan Lian | 川楝 | Chinaberry | Melia azedarach |
| H1000 | Dong Gua Zi | 冬瓜子 | Chinese waxgourd seed | Benincasa hispida |
| H0093 | Ju Pi | 橘皮 | Tangerine pericarp | Citrus reticulata |
| H0665 | Chai Hu Shao | 柴胡梢 | Chinese thorowax | Bupleurum chinense |
| H0028 | Jiang Huang | 姜黄 | Common turmeric | Curcuma longa |
| H0998 | Dong Gua Pi | 冬瓜皮 | Chinese waxgourd peel | Benincasa hispida |
| H0750 | Yin Xing Ye | 银杏叶 | Folium ginkgo | Ginkgo biloba |
| H0217 | Man Jing Zi | 蔓荆子 | Threeleaf chastetree fruit | Vitex trifolia |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H0216 | Man Jing Ye | 蔓荆叶 | Threeleaf chastetree leaf | Vitex trifolia |
| H0446 | Sheng Jiang | 生姜 | Fresh common ginger | Zingiber officinale |
| H0473 | Shu Di Huang | 熟地黄 | Adhesive rehmannia cocked root | Rehmannia glutinosa |
| H0695 | Ya Dan Zi | 鸦胆子 | Java brucea | Brucea javanica |
| H0057 | Jin Sha Teng | 金沙藤 | NA | Lygodium japonicum |
| H0239 | Bei Sha Shen | 北沙参 | Coastal glehnia | Glehnia littoralis |
| H1204 | Hu Jiao | 胡椒 | Black pepper | Piper nigrum |
| H1203 | Hu Ji Sheng | 槲寄生 | Colored mistletoe | Viscum coloratum |
| H0688 | Xuan Shen | 玄参 | Ningpo figwort | Scrophularia ningpoensis |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0869 | Ba Dou | 巴豆 | Pu rging croton | Croton tiglium |
| H0053 | Jin Lian Hua | 金莲花 | Chinese globeflower | Trollius chinensis |
| H0242 | Bei Sha Shen Liu Jin Gao | 北沙参流浸膏 | Glehnia littoralis | Glehnia littoralis |
| H0255 | Mao Zhao Cao | 猫爪草 | Root of catclaw buttercup | Ranunculus ternatus |
| H0769 | Yuan Zhi | 远志 | Thinleaf milkwort | Polygala tenuifolia |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H1181 | Hei Zhi Ma | 黑芝麻 | Oriental sesame | Sesamum indicum |
| H0529 | Tao Ren | 桃仁 | Peach kernel | Prunus persica |
| H0204 | Ma Ren | 麻仁 | NA | Cannabis sativa |
| H1011 | Bai Chou | 白丑 | Pharbitis seed | Semen pharbitidis |
| H0990 | Ding Xiang | 丁香 | Clove tree | Syzygium aromaticum |
| H0125 | Lai Fu | 莱菔 | Garden radish | Raphanus sativus |
| H0258 | Mo Han Lian | 墨旱莲 | Yerbadetajo | Eclipta prostrata |
| H0821 | Chu Ling Dan Cao | 臭灵丹草 | laggera pterodonta | Laggera pterodonta |
| H0570 | Tu Fu Ling | 土茯苓 | Glabrous greenbrier | Smilax glabra |
| H1077 | Bai Hu Jiao | 白胡椒 | white pepper | Piper nigrum |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
| H0233 | Mao Liang Mian Zhen | 毛两面针 | NA | Zanthoxylum nitidum |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0768 | Yuan Shen | 元参 | Figwort root | Scrophularia ningpoensis |
| H1231 | Huang Bai Tan | 黄柏炭 | Amur corktree | Phellodendron amurense |
| H1228 | Huang Bai | 黄柏 | Amur corktree | Phellodendron amurense |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H1149 | Hai Jin Sha Teng | 海金沙藤 | NA | Lygodium japonicum |
| H1173 | Hei Chou | 黑丑 | Pharbitis seed | Semen pharbitidis |
| H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H1110 | Gua Lou Zi | 瓜蒌子 | mongolian snakegourd seed | Trichosanthes kirilowii maxim |
| H0972 | Di Huang | 地黄 | Rehmanniae | Rehmannia glutinosa |
| H1171 | He Zi Rou | 诃子肉 | Medicine terminalia | Terminalia chebula |
| H1115 | Guan Huang Bai | 关黄柏 | Amur cork tree | Phellodendron amurense |
| H1055 | Bai Guo Ren | 白果仁 | ginkgo | Ginkgo biloba |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H0547 | Cang Qing Guo | 藏青果 | Myrobalan | Terminalia chebula |
| H0484 | Shui Fei Ji | 水飞蓟 | St marys | Silybum marianum |
| H0250 | Mi Zi Wan | 蜜紫菀 | Tatarian aster | Aster tataricus |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H0380 | San Qi Gan Jin Gao | 三七干浸膏 | Sanchi | Panax notoginseng |
| H0679 | Xing Ren | 杏仁 | Apricot seed | Prunus armeniaca |
| H0770 | Yuan Zhi Jin Gao | 远志浸膏 | Thinleaf milkwort | Polygala tenuifolia |
| H0086 | Jiu Zi | 韭子 | Tuber onion seed | Allium tuberosum |
| H1207 | Hu Ma | 胡麻 | white seed of oriental sesame | Sesamum indicum |
| H0152 | Ling Zhi Jin Gao | 灵芝浸膏 | NA | Ganoderma lucidum |
| H1026 | Fan Hun Cao | 返魂草 | Tatarian aster | Aster tataricus |
Ckey description of the interaction between compound and target