Herb Description

Herb ID:   H0768 Chinese Character:   元参
English Name:  Figwort root Latin Name:  Scrophularia ningpoensis
Chinese Pin Yin :  Yuan Shen TCM-ID:  TCMH2553
Therapeutic Function in Chinese :  清热 Therapeutic Function in English:  Heat clearence
Herb Function:  Reduce heat from blood, nourish yin, quench fire, and counteract toxicity

Related Targets  (Total: 115)

Target idProtein NameGene SymbolUniprot IDNo.of Literature Evidence
T83YZD AcetylcholinesteraseACHE P22303
3 Reference(s)
T58XLK Tyrosine-protein phosphatase non-receptor type 1PTPN1 P18031
2 Reference(s)
T49ORJ Peroxisome proliferator-activated receptor alphaPPARA Q07869
4 Reference(s)
T36HAE D-amino-acid oxidaseDAO P14920
1 Reference(s)
T47H3O Heat shock protein HSP 90-alphaHSP90AA1 P07900
1 Reference(s)
T89GFN Macrophage migration inhibitory factorMIF P14174
1 Reference(s)
T16X77 Solute carrier family 15 member 1SLC15A1 P46059
1 Reference(s)
T70KPE Transient receptor potential cation channel subfamily V member 3TRPV3 Q8NET8
1 Reference(s)
T49TDM Matrix metalloproteinase-9MMP9 P14780
2 Reference(s)
T26KIE Transcription factor AP-1JUN P05412
1 Reference(s)
T06VX0 MAP/microtubule affinity-regulating kinase 4MARK4 Q96L34
2 Reference(s)
T98QOA DNA-dependent protein kinase catalytic subunitPRKDC P78527
2 Reference(s)
T67KTV Transient receptor potential cation channel subfamily V member 1TRPV1 Q8NER1
5 Reference(s)
T31EJG Apoptotic protease-activating factor 1APAF1 O14727
1 Reference(s)
T09INZ Transient receptor potential cation channel subfamily A member 1TRPA1 O75762
1 Reference(s)
T35QZO Cytochrome cCYCS P99999
1 Reference(s)
T80TUC Apoptosis regulator BAXBAX Q07812
3 Reference(s)
T26EZU Myc proto-oncogene proteinMYC P01106
2 Reference(s)
T85U8U Caspase-3CASP3 P42574
8 Reference(s)
T25NSJ Mitogen-activated protein kinase 3MAPK3 P27361
1 Reference(s)
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
2 Reference(s)
T05PKX Steroid 17-alpha-hydroxylase/17,20 lyaseCYP17A1 P05093
1 Reference(s)
T85S9Z Cholesterol side-chain cleavage enzyme, mitochondrialCYP11A1 P05108
1 Reference(s)
T21DZX Amine oxidase [flavin-containing] AMAOA P21397
2 Reference(s)
T25M2J Anoctamin-1ANO1 Q5XXA6
1 Reference(s)
T23P74 Caspase-9CASP9 P55211
3 Reference(s)
T50SJ8 5'-AMP-activated protein kinase catalytic subunit alpha-2PRKAA2 P54646
1 Reference(s)
T22OPB Nuclear factor erythroid 2-related factor 2NFE2L2 Q16236
2 Reference(s)
T25Y64 CholinesteraseBCHE P06276
1 Reference(s)
T81I4T 5'-AMP-activated protein kinase catalytic subunit alpha-1PRKAA1 Q13131
1 Reference(s)
T13KGH TyrosinaseTYR P14679
2 Reference(s)
T04H8Y Beta-secretase 1BACE1 P56817
1 Reference(s)
T13WH4 Interferon-induced, double-stranded RNA-activated protein kinaseEIF2AK2 P19525
8 Reference(s)
T30VNV MyeloperoxidaseMPO P05164
2 Reference(s)
T62P0D Collagenase 3MMP13 P45452
1 Reference(s)
T09H2Z Nitric oxide synthase, inducibleNOS2 P35228
3 Reference(s)
T74WWP Peroxisome proliferator-activated receptor deltaPPARD Q03181
1 Reference(s)
T14JSX PlasminogenPLG P00747
1 Reference(s)
T58J2Y Peroxisome proliferator-activated receptor gammaPPARG P37231
2 Reference(s)
T67LRH RNA-binding protein Musashi homolog 1MSI1 O43347
1 Reference(s)
T17CZC Tissue factorF3 P13726
1 Reference(s)
T23VMI Tumor necrosis factorTNF P01375
1 Reference(s)
T33OPP Interleukin-6IL6 P05231
1 Reference(s)
T41INV Nuclear receptor subfamily 1 group I member 3NR1I3 Q14994
1 Reference(s)
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
1 Reference(s)
T06Q1R Amine oxidase [flavin-containing] BMAOB P27338
1 Reference(s)
T69XVX Cytochrome P450 1B1CYP1B1 Q16678
1 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
3 Reference(s)
T38T1U Caspase-8CASP8 Q14790
1 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
4 Reference(s)
T53AOE Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptideTGFB1 P01137
1 Reference(s)
T64UH1 Nitric oxide synthase, endothelialNOS3 P29474
1 Reference(s)
T80XW6 Scavenger receptor class B member 1SCARB1 Q8WTV0
1 Reference(s)
T02DEN Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptideGCG P01275
2 Reference(s)
T74JJN Fatty acid synthaseFASN P49327
1 Reference(s)
T39YFG Trypsin-1PRSS1 P07477
1 Reference(s)
T54WR0 Fatty acid-binding protein 5FABP5 Q01469
1 Reference(s)
T21Q0D 3-hydroxy-3-methylglutaryl-coenzyme A reductaseHMGCR P04035
1 Reference(s)
T12T4H Brain-derived neurotrophic factorBDNF P23560
1 Reference(s)
T07S0E BDNF/NT-3 growth factors receptorNTRK2 Q16620
1 Reference(s)
T90XYZ C-reactive proteinCRP P02741
1 Reference(s)
T51WGR Pancreas/duodenum homeobox protein 1PDX1 P52945
1 Reference(s)
T43NBB Solute carrier family 2, facilitated glucose transporter member 2SLC2A2 P11168
2 Reference(s)
T89L4V InsulinINS P01308
2 Reference(s)
T38WWN Serum paraoxonase/arylesterase 1PON1 P27169
1 Reference(s)
T23YZF Peptidyl-glycine alpha-amidating monooxygenasePAM P19021
1 Reference(s)
T77FOL NeuromodulinGAP43 P17677
1 Reference(s)
T93VFT Endothelin-1EDN1 P05305
2 Reference(s)
T36SOV Plasminogen activator inhibitor 1SERPINE1 P05121
1 Reference(s)
T48UT8 Cholesteryl ester transfer proteinCETP P11597
1 Reference(s)
T32HPO Aspartyl aminopeptidaseDNPEP Q9ULA0
1 Reference(s)
T20H9F Stromelysin-1MMP3 P08254
1 Reference(s)
T02YLA Alpha-lactalbuminLALBA P00709
1 Reference(s)
T02HSM NeuroglobinNGB Q9NPG2
1 Reference(s)
T44LWL Transcription factor p65RELA Q04206
1 Reference(s)
T79KQO NF-kappa-B inhibitor alphaNFKBIA P25963
2 Reference(s)
T74QXI Serine/threonine-protein kinase mTORMTOR P42345
1 Reference(s)
T09BRP NAPKB_RS07820 NA
2 Reference(s)
T68SE0 Solute carrier family 2, facilitated glucose transporter member 4SLC2A4 P14672
1 Reference(s)
T01QLH Estrogen receptorESR1 P03372
4 Reference(s)
T88AJI Hypoxia-inducible factor 1-alphaHIF1A Q16665
1 Reference(s)
T42HHN Follicle-stimulating hormone receptorFSHR P23945
1 Reference(s)
T90ADC BH3-interacting domain death agonistBID P55957
1 Reference(s)
T05O6O Estrogen receptor betaESR2 Q92731
1 Reference(s)
T09KPZ VimentinVIM P08670
1 Reference(s)
T84W8G Aryl hydrocarbon receptorAHR P35869
1 Reference(s)
T39M6J ATP-binding cassette sub-family C member 2ABCC2 Q92887
1 Reference(s)
T14ENF Microtubule-associated protein 2MAP2 P11137
1 Reference(s)
T78ZF2 Protein kinase C alpha typePRKCA P17252
1 Reference(s)
T60UPF Parvalbumin alphaPVALB P20472
2 Reference(s)
T69RXK Cytochrome P450 2C9CYP2C9 P11712
1 Reference(s)
T18CUI Neuron-specific calcium-binding protein hippocalcinHPCA P84074
1 Reference(s)
T92BZ2 Catenin beta-1CTNNB1 P35222
1 Reference(s)
T54CIF Interleukin-8CXCL8 P10145
1 Reference(s)
T39RV3 Dual specificity mitogen-activated protein kinase kinase 1MAP2K1 Q02750
1 Reference(s)
T66S13 Dual specificity mitogen-activated protein kinase kinase 2MAP2K2 P36507
1 Reference(s)
T08SJX Astrocytic phosphoprotein PEA-15PEA15 Q15121
1 Reference(s)
T38OQ4 Peroxiredoxin-2PRDX2 P32119
1 Reference(s)
T38J3Y Gamma-enolaseENO2 P09104
1 Reference(s)
T82I7J C-C motif chemokine 16CCL16 O15467
1 Reference(s)
T70HC9 Hepatocyte nuclear factor 1-alphaHNF1A P20823
1 Reference(s)
T49J7I Hepatocyte nuclear factor 4-alphaHNF4A P41235
1 Reference(s)
T67RBZ Mitochondrial uncoupling protein 2UCP2 P55851
2 Reference(s)
T67HYX Mitochondrial uncoupling protein 3UCP3 P55916
1 Reference(s)
T19EKF CholecystokininCCK P06307
1 Reference(s)
T19XSL Fatty acid-binding protein, liverFABP1 P07148
1 Reference(s)
T23APZ Retinol-binding protein 2RBP2 P50120
1 Reference(s)
T38K2W Receptor tyrosine-protein kinase erbB-2ERBB2 P04626
1 Reference(s)
T03NWF Sterol O-acyltransferase 1SOAT1 P35610
1 Reference(s)
T48YPL Aquaporin-3AQP3 Q92482
1 Reference(s)
T53SLQ Aquaporin-9AQP9 O43315
1 Reference(s)
T75EH8 Glucagon-like peptide 1 receptorGLP1R P43220
1 Reference(s)
T52VL6 Signal transducer and activator of transcription 5ASTAT5A P42229
1 Reference(s)
T19K8W Signal transducer and activator of transcription 5BSTAT5B P51692
1 Reference(s)
T10HL8 Intercellular adhesion molecule 1ICAM1 P05362
1 Reference(s)

Related Compounds  (Total: 14)

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C1243
Name: Cinnamic Acid
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C1030
Name: Aucubin
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C1166
Name: Benzoic Acid
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C0479
Name: Vanillin
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C0014
Name: Dibutyl Phthalate