Target Description
| Type | Detail |
|---|---|
| Target ID | T85S9Z |
| Protein Name | Cholesterol side-chain cleavage enzyme, mitochondrial |
| Uniprot ID |
P05108 |
| Protein Name Alias | EC 1.14.15.6; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc) |
| Gene ID |
1583 |
| Gene Symbol | CYP11A1 |
| Gene Alias | CYP11A |
| TTD | T23145: Successful target |
| Pfam | PF00067 |
| GO |
0005759:mitochondrial matrix
0008203:cholesterol metabolic process 0005743:mitochondrial inner membrane 0008386:cholesterol monooxygenase (side-chain-cleaving) activity 0006700:C21-steroid hormone biosynthetic process 0042359:vitamin D metabolic process 0016125:sterol metabolic process 0020037:heme binding 0071375:cellular response to peptide hormone stimulus 0034650:cortisol metabolic process 0005506:iron ion binding 0006704:glucocorticoid biosynthetic process 0005739:mitochondrion |
| PDB | 3NA0 ; 3NA1 ; 3N9Z ; 3N9Y |
| Drugbank | DB00153 ; DB00357 ; DB00169 ; DB13943 ; DB01396 ; DB02901 ; DB01437 ; DB00390 ; DB13944 ; DB00624 ; DB13946 |
| KEGG | hsa:1583 |
Related Compounds (Total: 4)
C0014
Name: Dibutyl Phthalate
C0325
Name: Progesterone
C0972
Name: digoxin
C1233
Name: Cholecalciferol
Related Herbs (Total: 65)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1154 | Hai Zao | 海藻 | seaweed | Sargassum |
| H0365 | Rou Dou Kou | 肉豆蔻 | Common nutmeg | Myristica fragrans |
| H0004 | Huo Xiang | 藿香 | Patchouli | Pogostemon cablin |
| H0450 | Shi Chang Pu | 石菖蒲 | Grassleaved sweetflag | Acorus tatarinowii |
| H0933 | Da Ji(1) | 大蓟 | NA | Herba cirsii japonici |
| H0243 | Mi Kuan Dong Hua | 蜜款冬花 | Common coltsfoot | Tussilago farfara |
| H0065 | Jin Yin Hua Ti Qu Ye | 金银花提取液 | Japanese honeysuckle | Lonicera japonica |
| H0818 | Zhi Zi | 栀子 | Cape jasmine fruit | Gardenia jasminoides |
| H0134 | Li Zhi He | 荔枝核 | Lychee seed | Litchi chinensis |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H0103 | Ai Ye | 艾叶 | Argy wormwood leaf | Artemisia argyi |
| H0496 | Shui Ze Lan | 水泽兰 | NA | Lycopus lucidus |
| H1010 | Du Huo Xiang | 杜藿香 | Patchouli | Pogostemon cablin |
| H1129 | Guang Xi E Zhu | 广西莪术 | rhizome of kwangsi turmeric | Rhizoma curcumae |
| H0297 | Niu Xi | 牛膝 | Twotooth achyranthes | Achyranthes bidentata |
| H0572 | Tu Huo Xiang | 土藿香 | Patchouli | Pogostemon cablin |
| H0452 | Shi Chang Pu Qing Gao | 石菖蒲清膏 | Grassleaved sweetflag | Acorus tatarinowii |
| H0974 | Di Jin Cao | 地锦草 | Humifuse euphorbia | Euphorbia humifusa |
| H0427 | Shan Zhu Yu | 山茱萸 | Asiatic cornelian cherry | Cornus officinalis |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H0424 | Shan Zhi | 山栀 | Cape jasmine | Gardenia jasminoides |
| H0930 | Da Ji Gen | 大蓟根 | NA | Herba cirsii japonici |
| H0608 | Wu Wei Zi Jin Gao | 五味子浸膏 | Five-flavor berry | Schisandra chinensis |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |
| H1051 | Bai Guo | 白果 | Ginkgo nut | Ginkgo biloba |
| H0219 | Man Shan Hong | 满山红 | Dahurian rhododendron | Rhododendron dauricum |
| H0819 | Zhi Zi Jin Gao | 栀子浸膏 | Cape jasmine fruit | Gardenia jasminoides |
| H0115 | Kuan Dong Hua | 款冬花 | Common coltsfoot | Tussilago farfara |
| H0451 | Shi Chang Pu Jin Gao | 石菖蒲浸膏 | Grassleaved sweetflag | Acorus tatarinowii |
| H0354 | Ren Dong Teng | 忍冬藤 | Japanese honeysuckle vine | Lonicera japonica |
| H1022 | E Zhu | 莪术 | Zedoray rhizome | Curcuma aeruginosa |
| H0613 | Wu Yue Ai | 五月艾 | Artemisia | Artemisia princeps |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H0085 | Jiu Yu Rou | 酒萸肉 | Asiatic cornelian cherry | Cornus officinalis |
| H0606 | Wu Wei Zi Chun Jin Gao | 五味子醇浸膏 | Five-flavor berry | Schisandra chinensis |
| H0768 | Yuan Shen | 元参 | Figwort root | Scrophularia ningpoensis |
| H0975 | Di Mian Cao | 地绵草 | NA | Euphorbia humifusa |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0296 | Niu Teng | 牛藤 | twotooth achyranthes root | Achyranthes bidentata |
| H0605 | Wu Wei Zi | 五味子 | Chinese magnoliavine | Schisandra chinensis |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0154 | Ai Ye You | 艾叶油 | Argy wormwood leaf | Artemisia argyi |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H1055 | Bai Guo Ren | 白果仁 | ginkgo | Ginkgo biloba |
| H0522 | Tai Zi Shen | 太子参 | Heterophylly falsestarwort root | Radix pseudostellariae |
| H0609 | Wu Wei Zi Liu Jin Gao | 五味子流浸膏 | Five-flavor berry | Schisandra chinensis |
| H0750 | Yin Xing Ye | 银杏叶 | Folium ginkgo | Ginkgo biloba |
| H0688 | Xuan Shen | 玄参 | Ningpo figwort | Scrophularia ningpoensis |
| H0370 | Ru Xiang | 乳香 | Olibanum | Boswellia carterii |
| H0931 | Da Ji Gen Jin Gao | 大蓟根浸膏 | NA | Herba cirsii japonici |
| H1120 | Guang Huo Xiang | 广藿香 | Patchouli | Pogostemon cablin |
| H0607 | Wu Wei Zi Jin Chu Wu | 五味子浸出物 | Five-flavor berry | Schisandra chinensis |
| H0697 | Ya Ma Zi | 亚麻子 | Common flax seed | Linum usitatissimum |
| H0005 | Huo Xiang Ye | 藿香叶 | Patchouli | Pogostemon cablin |
| H0064 | Jin Yin Hua | 金银花 | Japanese honeysuckle | Lonicera japonica |
| H0307 | Peng E Zhu | 蓬莪术 | Zedoray rhizome | Rhizoma curcumae |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H1229 | Bai Mu Xiang | 白木香 | Chinese eaglewood | Aquilaria sinensis |
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |