Compound Description

ID:   C1233 Common name:   Cholecalciferol
IUPAC:  (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol CAS:  CAS:67-97-0
Chembl ID:   CHEMBL1042 Pubchem ID:   CID:5280795
Formula:  C27H44O TCM-ID:  TCMC901
Smiles:  CC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C
Alias:

9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3β,5Z,7E)-;

Cholecalciferol;

(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylenecyclohexanol;

9,10-Secocholesta-5,7,10(19)-trien-3β-ol;

Aquadetrim;

Arachitol;

Calciol;

Calcirol;

Colecalciferol;

D3-Vigantol;

Decristol;

Delsterol;

Deparal;

Devaron;

Devikap;

Dry Vitamin D3 100CWS/AM;

Duphafral D3 1000;

Ekostop D3;

FeraCol;

Granuvit D3;

High-D 2X;

Lutavit D;

Minisun;

NSC 375571;

Oleovit D3;

Oleovitamin D3;

OsteVit D;

Plivit D3;

Quintox;

Ricketon;

Riken D3 Oil 100;

Riken D3 Oil 20;

Rovimix D3 500;

Trivitan;

UVEDOSE;

Vi-De3;

Videkhol;

Vigantol;

Vigantoletten;

Vigorsan;

Vitamin D3;

Vitamin D3 S 50t;

Vitinc Dan-Dee-3
Structure:

Related Targets  (Total: 52)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T52I9S 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialCYP27B1 O15528
A 1 Reference(s)
T85S9Z Cholesterol side-chain cleavage enzyme, mitochondrialCYP11A1 P05108
A 1 Reference(s)
T06RMZ Nuclear factor NF-kappa-B p105 subunitNFKB1 P19838
A 1 Reference(s)
T84AR4 Smoothened homologSMO Q99835
A 1 Reference(s)
T25NSJ Mitogen-activated protein kinase 3MAPK3 P27361
A 1 Reference(s)
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
A 1 Reference(s)
T82P0Z ReninREN P00797
B 1 Reference(s)
T88LSZ AromataseCYP19A1 P11511
B 1 Reference(s)
T44LWL Transcription factor p65RELA Q04206
B 1 Reference(s)
T03GOM Protein S100-GS100G P29377
B 1 Reference(s)
T49TDM Matrix metalloproteinase-9MMP9 P14780
B 1 Reference(s)
T80GUN 72 kDa type IV collagenaseMMP2 P08253
B 1 Reference(s)
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
B 1 Reference(s)
T50V79 Interleukin-4IL4 P05112
B 1 Reference(s)
T73WJH Calcium/calmodulin-dependent protein kinase kinase 2CAMKK2 Q96RR4
B 1 Reference(s)
T96QZX D site-binding proteinDBP Q10586
B 1 Reference(s)
T73AR5 Complement decay-accelerating factorCD55 P08174
B 1 Reference(s)
T17CNB ThioredoxinTXN P10599
B 1 Reference(s)
T37PX5 Zinc finger protein GLI1GLI1 P08151
B 1 Reference(s)
T15URL Cathelicidin antimicrobial peptideCAMP P49913
C 1 Reference(s)
T08OEP Monocyte differentiation antigen CD14CD14 P08571
C 1 Reference(s)
T33OPP Interleukin-6IL6 P05231
C 1 Reference(s)
T45CP6 Cysteine and glycine-rich protein 1CSRP1 P21291
C 1 Reference(s)
T76B0A Gap junction alpha-1 proteinGJA1 P17302
C 1 Reference(s)
T79KQO NF-kappa-B inhibitor alphaNFKBIA P25963
C 1 Reference(s)
T85JI5 Vitamin D3 receptorVDR P11473
C 1 Reference(s)
T20JZ2 Androgen receptorAR P10275
C 1 Reference(s)
T45XTW Retinoic acid receptor RXR-alphaRXRA P19793
C 1 Reference(s)
T64LXU 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialCYP24A1 Q07973
C 1 Reference(s)
T54CIF Interleukin-8CXCL8 P10145
C 1 Reference(s)
T86YQL ProlactinPRL P01236
C 1 Reference(s)
T16P5N Extracellular calcium-sensing receptorCASR P41180
C 1 Reference(s)
T11YIM ThyroglobulinTG P01266
C 1 Reference(s)
T69NG6 Interleukin-10IL10 P22301
C 1 Reference(s)
T22NX4 Toll-like receptor 2TLR2 O60603
C 1 Reference(s)
T16YT9 Parathyroid hormonePTH P01270
C 1 Reference(s)
T91EAB Insulin-like growth factor-binding protein 3IGFBP3 P17936
C 1 Reference(s)
T03G09 Tumor necrosis factor ligand superfamily member 11TNFSF11 O14788
C 1 Reference(s)
T93YV8 Tumor necrosis factor receptor superfamily member 11BTNFRSF11B O00300
C 1 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
C 1 Reference(s)
T32MXJ 7-dehydrocholesterol reductaseDHCR7 Q9UBM7
C 1 Reference(s)
T29WP4 Protransforming growth factor alpha [Cleaved into: Transforming growth factor alphaTGFA P01135
C 1 Reference(s)
T26RYP CD83 antigenCD83 Q01151
C 1 Reference(s)
T11R4S Tumor necrosis factor receptor superfamily member 5CD40 P25942
C 1 Reference(s)
T23OTN T-lymphocyte activation antigen CD80CD80 P33681
C 1 Reference(s)
T47MPW T-lymphocyte activation antigen CD86CD86 P42081
C 1 Reference(s)
T11BI7 Toll-like receptor 4TLR4 O00206
C 1 Reference(s)
T99ARN Forkhead box protein P3FOXP3 Q9BZS1
C 1 Reference(s)
T13QCS C-C chemokine receptor type 6CCR6 P51684
C 1 Reference(s)
T30A57 C-C chemokine receptor type 7CCR7 P32248
C 1 Reference(s)
T60H34 DysferlinDYSF O75923
C 1 Reference(s)
T80R6A Insulin-like growth factor IIGF1 P05019
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens