ID: C1233 | Common name: Cholecalciferol |
IUPAC: (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol | CAS: CAS:67-97-0 |
Chembl ID: CHEMBL1042 | Pubchem ID: CID:5280795 |
Formula: C27H44O | TCM-ID: TCMC901 |
Smiles: CC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C | |
Alias:
9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3β,5Z,7E)-;
Cholecalciferol; (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylenecyclohexanol; 9,10-Secocholesta-5,7,10(19)-trien-3β-ol; Aquadetrim; Arachitol; Calciol; Calcirol; Colecalciferol; D3-Vigantol; Decristol; Delsterol; Deparal; Devaron; Devikap; Dry Vitamin D3 100CWS/AM; Duphafral D3 1000; Ekostop D3; FeraCol; Granuvit D3; High-D 2X; Lutavit D; Minisun; NSC 375571; Oleovit D3; Oleovitamin D3; OsteVit D; Plivit D3; Quintox; Ricketon; Riken D3 Oil 100; Riken D3 Oil 20; Rovimix D3 500; Trivitan; UVEDOSE; Vi-De3; Videkhol; Vigantol; Vigantoletten; Vigorsan; Vitamin D3; Vitamin D3 S 50t; Vitinc Dan-Dee-3 |
Structure:
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Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
---|---|---|---|---|---|
T52I9S | 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial | CYP27B1 |
O15528 |
A | 1 Reference(s) |
T85S9Z | Cholesterol side-chain cleavage enzyme, mitochondrial | CYP11A1 |
P05108 |
A | 1 Reference(s) |
T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
A | 1 Reference(s) |
T84AR4 | Smoothened homolog | SMO |
Q99835 |
A | 1 Reference(s) |
T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
A | 1 Reference(s) |
T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
A | 1 Reference(s) |
T82P0Z | Renin | REN |
P00797 |
B | 1 Reference(s) |
T88LSZ | Aromatase | CYP19A1 |
P11511 |
B | 1 Reference(s) |
T44LWL | Transcription factor p65 | RELA |
Q04206 |
B | 1 Reference(s) |
T03GOM | Protein S100-G | S100G |
P29377 |
B | 1 Reference(s) |
T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
B | 1 Reference(s) |
T80GUN | 72 kDa type IV collagenase | MMP2 |
P08253 |
B | 1 Reference(s) |
T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
B | 1 Reference(s) |
T50V79 | Interleukin-4 | IL4 |
P05112 |
B | 1 Reference(s) |
T73WJH | Calcium/calmodulin-dependent protein kinase kinase 2 | CAMKK2 |
Q96RR4 |
B | 1 Reference(s) |
T96QZX | D site-binding protein | DBP |
Q10586 |
B | 1 Reference(s) |
T73AR5 | Complement decay-accelerating factor | CD55 |
P08174 |
B | 1 Reference(s) |
T17CNB | Thioredoxin | TXN |
P10599 |
B | 1 Reference(s) |
T37PX5 | Zinc finger protein GLI1 | GLI1 |
P08151 |
B | 1 Reference(s) |
T15URL | Cathelicidin antimicrobial peptide | CAMP |
P49913 |
C | 1 Reference(s) |
T08OEP | Monocyte differentiation antigen CD14 | CD14 |
P08571 |
C | 1 Reference(s) |
T33OPP | Interleukin-6 | IL6 |
P05231 |
C | 1 Reference(s) |
T45CP6 | Cysteine and glycine-rich protein 1 | CSRP1 |
P21291 |
C | 1 Reference(s) |
T76B0A | Gap junction alpha-1 protein | GJA1 |
P17302 |
C | 1 Reference(s) |
T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
C | 1 Reference(s) |
T85JI5 | Vitamin D3 receptor | VDR |
P11473 |
C | 1 Reference(s) |
T20JZ2 | Androgen receptor | AR |
P10275 |
C | 1 Reference(s) |
T45XTW | Retinoic acid receptor RXR-alpha | RXRA |
P19793 |
C | 1 Reference(s) |
T64LXU | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | CYP24A1 |
Q07973 |
C | 1 Reference(s) |
T54CIF | Interleukin-8 | CXCL8 |
P10145 |
C | 1 Reference(s) |
T86YQL | Prolactin | PRL |
P01236 |
C | 1 Reference(s) |
T16P5N | Extracellular calcium-sensing receptor | CASR |
P41180 |
C | 1 Reference(s) |
T11YIM | Thyroglobulin | TG |
P01266 |
C | 1 Reference(s) |
T69NG6 | Interleukin-10 | IL10 |
P22301 |
C | 1 Reference(s) |
T22NX4 | Toll-like receptor 2 | TLR2 |
O60603 |
C | 1 Reference(s) |
T16YT9 | Parathyroid hormone | PTH |
P01270 |
C | 1 Reference(s) |
T91EAB | Insulin-like growth factor-binding protein 3 | IGFBP3 |
P17936 |
C | 1 Reference(s) |
T03G09 | Tumor necrosis factor ligand superfamily member 11 | TNFSF11 |
O14788 |
C | 1 Reference(s) |
T93YV8 | Tumor necrosis factor receptor superfamily member 11B | TNFRSF11B |
O00300 |
C | 1 Reference(s) |
T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
C | 1 Reference(s) |
T32MXJ | 7-dehydrocholesterol reductase | DHCR7 |
Q9UBM7 |
C | 1 Reference(s) |
T29WP4 | Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha | TGFA |
P01135 |
C | 1 Reference(s) |
T26RYP | CD83 antigen | CD83 |
Q01151 |
C | 1 Reference(s) |
T11R4S | Tumor necrosis factor receptor superfamily member 5 | CD40 |
P25942 |
C | 1 Reference(s) |
T23OTN | T-lymphocyte activation antigen CD80 | CD80 |
P33681 |
C | 1 Reference(s) |
T47MPW | T-lymphocyte activation antigen CD86 | CD86 |
P42081 |
C | 1 Reference(s) |
T11BI7 | Toll-like receptor 4 | TLR4 |
O00206 |
C | 1 Reference(s) |
T99ARN | Forkhead box protein P3 | FOXP3 |
Q9BZS1 |
C | 1 Reference(s) |
T13QCS | C-C chemokine receptor type 6 | CCR6 |
P51684 |
C | 1 Reference(s) |
T30A57 | C-C chemokine receptor type 7 | CCR7 |
P32248 |
C | 1 Reference(s) |
T60H34 | Dysferlin | DYSF |
O75923 |
C | 1 Reference(s) |
T80R6A | Insulin-like growth factor I | IGF1 |
P05019 |
C | 1 Reference(s) |