HIT-result

Target Description

Type	Detail
Target ID	T15URL
Protein Name	Cathelicidin antimicrobial peptide
Uniprot ID	P49913
Protein Name Alias	18 kDa cationic antimicrobial protein; CAP-18; hCAP-18
Gene ID	820
Gene Symbol	CAMP
Gene Alias	CAP18; FALL39
TTD	T34318: Successful target
Pfam	PF12153
GO	0005615:extracellular space 0002227:innate immune response in mucosa 0002544:chronic inflammatory response 0042581:specific granule 0032757:positive regulation of interleukin-8 production 0042742:defense response to bacterium 0035821:modulation of process of other organism 0005576:extracellular region 0050830:defense response to Gram-positive bacterium 0001530:lipopolysaccharide binding 0001878:response to yeast 0045087:innate immune response 1904724:tertiary granule lumen 0050829:defense response to Gram-negative bacterium 0043312:neutrophil degranulation 0019730:antimicrobial humoral response 0051838:cytolysis by host of symbiont cells 0035580:specific granule lumen 0019732:antifungal humoral response 0070062:extracellular exosome 0051873:killing by host of symbiont cells 0061844:antimicrobial humoral immune response mediated by antimicrobial peptide 0019731:antibacterial humoral response
PDB	5NMN ; 2FCG ; 5NNM ; 2FBU ; 5XNG ; 5NNK ; 6BIX ; 5NNT ; 2K6O ; 2NA3 ; 4EYC ; 6S6N ; 2FBS ; 6S6M ; 6BIV ; 5XRX ; 2LMF
Drugbank	DB02345
KEGG	hsa:820

Type

Detail

Target ID

T15URL

Protein Name

Cathelicidin antimicrobial peptide

Uniprot ID

P49913

Protein Name Alias

18 kDa cationic antimicrobial protein; CAP-18; hCAP-18

Gene ID

820

Gene Symbol

CAMP

Gene Alias

CAP18; FALL39

TTD

T34318: Successful target

Pfam

PF12153

0005615:extracellular space

0002227:innate immune response in mucosa

0002544:chronic inflammatory response

0042581:specific granule

0032757:positive regulation of interleukin-8 production

0042742:defense response to bacterium

0035821:modulation of process of other organism

0005576:extracellular region

0050830:defense response to Gram-positive bacterium

0001530:lipopolysaccharide binding

0001878:response to yeast

0045087:innate immune response

1904724:tertiary granule lumen

0050829:defense response to Gram-negative bacterium

0043312:neutrophil degranulation

0019730:antimicrobial humoral response

0051838:cytolysis by host of symbiont cells

0035580:specific granule lumen

0019732:antifungal humoral response

0070062:extracellular exosome

0051873:killing by host of symbiont cells

0061844:antimicrobial humoral immune response mediated by antimicrobial peptide

0019731:antibacterial humoral response

PDB

5NMN ; 2FCG ; 5NNM ; 2FBU ; 5XNG ; 5NNK ; 6BIX ; 5NNT ; 2K6O ; 2NA3 ; 4EYC ; 6S6N ; 2FBS ; 6S6M ; 6BIV ; 5XRX ; 2LMF

Drugbank

DB02345

KEGG

hsa:820

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Name: Serotonin

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Name: 25-Hydroxycholecalciferol

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Name: Calcitriol

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Name: Cholecalciferol

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Name: Curcumin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0556	Tie Xian Cao	铁线草	NA	Adiantum capillus-veneris
H0142	Liang Jiang	良姜	NA	Alpinia officinarum
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H1092	Gao Liang Jiang	高良姜	Lesser galangal	Alpinia officinarum
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H1093	Gao Liang Jiang You	高良姜油	Lesser galangal	Alpinia officinarum
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H1078	Gan Chan	干蟾	NA	Bufo melanostictus
H0761	Yu Jin	郁金	AromaticTurmeric	Curcuma aromatica
H0895	Chuan Yu Jin	川郁金	Turmeric	Curcuma longa
H0677	Chan Chu	蟾蜍	Toad	Bufo melanostictus
H0028	Jiang Huang	姜黄	Common turmeric	Curcuma longa

Target Description

Related Compounds (Total: 5)

Related Herbs (Total: 14)