ID: C0397 | Common name: Serotonin |
IUPAC: 3-(2-aminoethyl)-1H-indol-5-ol | CAS: CAS:50-67-9 |
Chembl ID: CHEMBL39 | Pubchem ID: CID:5202 |
Formula: C10H12N2O | TCM-ID: TCMC2063 |
Smiles: NCCc1c[nH]c2c1cc(O)cc2 | |
Alias:
Indol-5-ol, 3-(2-aminoethyl)-;
3-(2-Aminoethyl)-1H-indol-5-ol; 3-(2-Aminoethyl)indol-5-ol; 3-(β-Aminoethyl)-5-hydroxyindole; 5-HT; 5-HTA; 5-Hydroxy-3-(β-aminoethyl)indole; 5-Hydroxyltryptamine; 5-Hydroxytriptamine; 5-Hydroxytryptamine; DS substance; Enteramin; Enteramine; Serotonin; Substance DS; Thrombocytin; Thrombotonin; Tryptamine, 5-hydroxy- |
Structure: |
Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
---|---|---|---|---|---|
T11ZYR | Cytochrome P450 2D6 | CYP2D6 |
P10635 |
A | 2 Reference(s) |
T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
A | 3 Reference(s) |
T24OK4 | Rho-associated protein kinase 2 | Rock2 |
Q62868 |
A | 1 Reference(s) |
T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
A | 2 Reference(s) |
T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
A | 2 Reference(s) |
T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
A | 1 Reference(s) |
T25Y64 | Cholinesterase | BCHE |
P06276 |
A | 1 Reference(s) |
T76C5R | Parathyroid hormone-related protein | PTHLH |
P12272 |
A | 1 Reference(s) |
T77WRE | Inactive cytidine monophosphate-N-acetylneuraminic acid hydroxylase | CMAHP |
Q9Y471 |
A | 1 Reference(s) |
T13KGH | Tyrosinase | TYR |
P14679 |
A | 1 Reference(s) |
T83COK | 5-hydroxytryptamine receptor 2C | HTR2C |
P28335 |
A | 1 Reference(s) |
T39T57 | Tryptophan 5-hydroxylase 1 | TPH1 |
P17752 |
A | 1 Reference(s) |
T61NZN | Progonadoliberin-1 | GNRH1 |
P01148 |
A | 1 Reference(s) |
T29B10 | Interleukin-17A | IL17A |
Q16552 |
A | 1 Reference(s) |
T13HNJ | NA | TERC |
NA |
A | 1 Reference(s) |
T84YTJ | Glutamate receptor 4 | GRIA4 |
P48058 |
A | 1 Reference(s) |
T03GNH | Alpha-2B adrenergic receptor | ADRA2B |
P18089 |
A | 1 Reference(s) |
T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
A | 1 Reference(s) |
T39GNZ | 5-hydroxytryptamine receptor 3A | HTR3A |
P46098 |
A | 1 Reference(s) |
T97ZTQ | 5-hydroxytryptamine receptor 1B | HTR1B |
P28222 |
A | 1 Reference(s) |
T86YQL | Prolactin | PRL |
P01236 |
A | 1 Reference(s) |
T48ZIG | D(2) dopamine receptor | DRD2 |
P14416 |
A | 1 Reference(s) |
T36O3K | Beta-adrenergic receptor kinase 1 | GRK2 |
P25098 |
A | 1 Reference(s) |
T31QEZ | 5-hydroxytryptamine receptor 1A | HTR1A |
P08908 |
A | 1 Reference(s) |
T84W8G | Aryl hydrocarbon receptor | AHR |
P35869 |
A | 1 Reference(s) |
T64BED | 5-hydroxytryptamine receptor 2A | HTR2A |
P28223 |
A | 1 Reference(s) |
T25RHJ | Sodium-dependent serotonin transporter | SLC6A4 |
P31645 |
B | 1 Reference(s) |
T78BSU | 5-hydroxytryptamine receptor 2B | HTR2B |
P41595 |
B | 1 Reference(s) |
T04MBA | Vascular endothelial growth factor receptor 2 | KDR |
P35968 |
B | 1 Reference(s) |
T17UP9 | C-C motif chemokine 2 | CCL2 |
P13500 |
C | 1 Reference(s) |
T53Z7Y | Transcriptional coactivator YAP1 | YAP1 |
P46937 |
C | 2 Reference(s) |
T69XVX | Cytochrome P450 1B1 | CYP1B1 |
Q16678 |
C | 2 Reference(s) |
T91MKC | Runt-related transcription factor 2 | RUNX2 |
Q13950 |
C | 1 Reference(s) |
T94H37 | Cadherin-1 | CDH1 |
P12830 |
C | 1 Reference(s) |
T73ZPO | Beta-casein | CSN2 |
P05814 |
C | 1 Reference(s) |
T54CIF | Interleukin-8 | CXCL8 |
P10145 |
C | 1 Reference(s) |
T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
C | 1 Reference(s) |
T52VL6 | Signal transducer and activator of transcription 5A | STAT5A |
P42229 |
C | 1 Reference(s) |
T19K8W | Signal transducer and activator of transcription 5B | STAT5B |
P51692 |
C | 1 Reference(s) |
T15URL | Cathelicidin antimicrobial peptide | CAMP |
P49913 |
C | 1 Reference(s) |
T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
C | 1 Reference(s) |
T76TED | Pro-opiomelanocortin | POMC |
P01189 |
C | 1 Reference(s) |
T20E5P | Cytochrome b-245 heavy chain | CYBB |
P04839 |
C | 1 Reference(s) |
T67HXL | Glial cell line-derived neurotrophic factor | GDNF |
P39905 |
C | 1 Reference(s) |
T91MWA | Disintegrin and metalloproteinase domain-containing protein 17 | ADAM17 |
P78536 |
C | 1 Reference(s) |
T53TBQ | Elongation factor 2 | EEF2 |
P13639 |
C | 1 Reference(s) |
T13M0G | Protein S100-B | S100B |
P04271 |
C | 1 Reference(s) |
T01QLH | Estrogen receptor | ESR1 |
P03372 |
C | 1 Reference(s) |
T34ZZ0 | Potassium channel subfamily K member 2 | KCNK2 |
O95069 |
C | 1 Reference(s) |
Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
---|---|---|---|---|
H0677 | Chan Chu | 蟾蜍 | Toad | Bufo melanostictus |
H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
H1078 | Gan Chan | 干蟾 | NA | Bufo melanostictus |
H0926 | Da Huang | 大黄 | Medicinal rhubarb | Rheum officinale |
H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
H0928 | Da Huang Liu Jin Gao | 大黄流浸膏 | Medicinal rhubarb | Rheum officinale |
H0927 | Da Huang Jin Gao | 大黄浸膏 | Medicinal rhubarb | Rheum officinale |