HIT-result

Target Description

Type	Detail
Target ID	T76C5R
Protein Name	Parathyroid hormone-related protein
Uniprot ID	P12272
Protein Name Alias	PTH-rP; PTHrP; Parathyroid hormone-like protein; PLP
Gene ID	5744
Gene Symbol	PTHLH
Gene Alias	PTHRP
TTD	NA
Pfam	PF01279
GO	0046058:cAMP metabolic process 0032331:negative regulation of chondrocyte differentiation 0051428:peptide hormone receptor binding 0005829:cytosol 0010468:regulation of gene expression 0061182:negative regulation of chondrocyte development 0030282:bone mineralization 0008284:positive regulation of cell population proliferation 0008285:negative regulation of cell population proliferation 0007189:adenylate cyclase-activating G protein-coupled receptor signaling pathway 0005615:extracellular space 0002862:negative regulation of inflammatory response to antigenic stimulus 0005179:hormone activity 0007267:cell-cell signaling 0008544:epidermis development 0005576:extracellular region 0005794:Golgi apparatus 0032330:regulation of chondrocyte differentiation 0005737:cytoplasm 0007186:G protein-coupled receptor signaling pathway 0005654:nucleoplasm 0001501:skeletal system development 0007565:female pregnancy 0002076:osteoblast development
PDB	1BZG ; 1M5N ; 3H3G ; 1ET3 ; 3FFD
Drugbank	NA
KEGG	hsa:5744

Type

Detail

Target ID

T76C5R

Protein Name

Parathyroid hormone-related protein

Uniprot ID

P12272

Protein Name Alias

PTH-rP; PTHrP; Parathyroid hormone-like protein; PLP

Gene ID

5744

Gene Symbol

PTHLH

Gene Alias

PTHRP

TTD

Pfam

PF01279

0046058:cAMP metabolic process

0032331:negative regulation of chondrocyte differentiation

0051428:peptide hormone receptor binding

0005829:cytosol

0010468:regulation of gene expression

0061182:negative regulation of chondrocyte development

0030282:bone mineralization

0008284:positive regulation of cell population proliferation

0008285:negative regulation of cell population proliferation

0007189:adenylate cyclase-activating G protein-coupled receptor signaling pathway

0005615:extracellular space

0002862:negative regulation of inflammatory response to antigenic stimulus

0005179:hormone activity

0007267:cell-cell signaling

0008544:epidermis development

0005576:extracellular region

0005794:Golgi apparatus

0032330:regulation of chondrocyte differentiation

0005737:cytoplasm

0007186:G protein-coupled receptor signaling pathway

0005654:nucleoplasm

0001501:skeletal system development

0007565:female pregnancy

0002076:osteoblast development

PDB

1BZG ; 1M5N ; 3H3G ; 1ET3 ; 3FFD

Drugbank

KEGG

hsa:5744

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1134	Bai Jiang Can	白僵蚕	Silkworm larva	Bombyx mori
H1176	Hei Hu Jiao	黑胡椒	Black pepper	Piper nigrum
H1133	Gui Jian Yu	鬼箭羽	Winged euonymus	Euonymus alatus
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0476	Can E	蚕蛾	Silkworm	Bombyx mori
H0490	Can Jian	蚕茧	Silk cocoon	Bombyx mori
H0495	Can Sha	蚕砂	Silkworm excrement	Bombyx mori
H1077	Bai Hu Jiao	白胡椒	white pepper	Piper nigrum
H1078	Gan Chan	干蟾	NA	Bufo melanostictus
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H0500	Can Yong	蚕蛹	Silkworm chrysalis	Bombyx mori
H0677	Chan Chu	蟾蜍	Toad	Bufo melanostictus
H1204	Hu Jiao	胡椒	Black pepper	Piper nigrum

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 16)