Target Description
| Type | Detail |
|---|---|
| Target ID | T39T57 |
| Protein Name | Tryptophan 5-hydroxylase 1 |
| Uniprot ID |
P17752 |
| Protein Name Alias | EC 1.14.16.4; Tryptophan 5-monooxygenase 1 |
| Gene ID |
7166 |
| Gene Symbol | TPH1 |
| Gene Alias | TPH; TPRH; TRPH |
| TTD | T78915: Clinical Trial target |
| Pfam | PF00351 |
| GO |
0060749:mammary gland alveolus development
0009072:aromatic amino acid family metabolic process 0042427:serotonin biosynthetic process 0030279:negative regulation of ossification 0004510:tryptophan 5-monooxygenase activity 0045600:positive regulation of fat cell differentiation 0007623:circadian rhythm 0046219:indolalkylamine biosynthetic process 0046849:bone remodeling 0043005:neuron projection 0005829:cytosol 0035902:response to immobilization stress 0005506:iron ion binding |
| PDB | 3HF8 ; 1IN9 ; 1MLW ; 5J6D ; 3HFB ; 5L01 ; 3HF6 ; 5TPG |
| Drugbank | DB05199 ; DB00150 ; DB00360 ; DB12095 |
| KEGG | hsa:7166 |
Related Herbs (Total: 7)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0927 | Da Huang Jin Gao | 大黄浸膏 | Medicinal rhubarb | Rheum officinale |
| H0677 | Chan Chu | 蟾蜍 | Toad | Bufo melanostictus |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H1078 | Gan Chan | 干蟾 | NA | Bufo melanostictus |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0926 | Da Huang | 大黄 | Medicinal rhubarb | Rheum officinale |
| H0928 | Da Huang Liu Jin Gao | 大黄流浸膏 | Medicinal rhubarb | Rheum officinale |