Target Description

Type Detail
Target ID T39GNZ
Protein Name 5-hydroxytryptamine receptor 3A
Uniprot ID P46098
Protein Name Alias 5-HT3-A;  5-HT3A;  5-hydroxytryptamine receptor 3;  5-HT-3;  5-HT3R;  Serotonin receptor 3A;  Serotonin-gated ion channel receptor
Gene ID 3359
Gene Symbol HTR3A
Gene Alias 5HT3R;  HTR3
TTD T64591: Successful target
Pfam PF02931 ; PF02932
GO
0051378:serotonin binding

0022850:serotonin-gated cation-selective channel activity

0050877:nervous system process

0045202:synapse

0030594:neurotransmitter receptor activity

0032414:positive regulation of ion transmembrane transporter activity

0042391:regulation of membrane potential

0098978:glutamatergic synapse

0099056:integral component of presynaptic membrane

0007165:signal transduction

1904602:serotonin-activated cation-selective channel complex

0034220:ion transmembrane transport

0045471:response to ethanol

0099055:integral component of postsynaptic membrane

0042220:response to cocaine

0043025:neuronal cell body

0005886:plasma membrane

0005887:integral component of plasma membrane

0030424:axon

0032154:cleavage furrow

0043005:neuron projection

0005737:cytoplasm

0004888:transmembrane signaling receptor activity

0007268:chemical synaptic transmission

0071363:cellular response to growth factor stimulus

PDB NA
Drugbank DB13345 ; DB00333 ; DB01199 ; DB00604 ; DB04917 ; DB12141 ; DB00363 ; DB00969 ; DB01239 ; DB00721 ; DB01238 ; DB00246 ; DB06422 ; DB00726 ; DB04885 ; DB11699 ; DB00988 ; DB00408 ; DB01156 ; DB00898 ; DB05642 ; DB01233 ; DB00889 ; DB14185 ; DB00757 ; DB11273 ; DB00555 ; DB00377 ; DB13025 ; DB01049 ; DB08839 ; DB09304 ; DB00543 ; DB06204 ; DB05049 ; DB00715 ; DB00904 ; DB09290 ; DB09061 ; DB00334 ; DB09068 ; DB01043 ; DB01221 ; DB00728 ; DB01224
KEGG hsa:3359

Related Compounds  (Total: 2)

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C0397
Name: Serotonin
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C1096
Name: ginsenoside rg3


Related Herbs  (Total: 7)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0677 Chan Chu蟾蜍 ToadBufo melanostictus
H0928 Da Huang Liu Jin Gao大黄流浸膏 Medicinal rhubarbRheum officinale
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0926 Da Huang大黄 Medicinal rhubarbRheum officinale
H0927 Da Huang Jin Gao大黄浸膏 Medicinal rhubarbRheum officinale
H1078 Gan Chan干蟾 NABufo melanostictus
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens