Target Description

Type Detail
Target ID T03GNH
Protein Name Alpha-2B adrenergic receptor
Uniprot ID P18089
Protein Name Alias Alpha-2 adrenergic receptor subtype C2;  Alpha-2B adrenoreceptor;  Alpha-2B adrenoceptor;  Alpha-2BAR
Gene ID 151
Gene Symbol ADRA2B
Gene Alias ADRA2L1;  ADRA2RL1
TTD T41580: Successful target
Pfam PF00001
GO
0043410:positive regulation of MAPK cascade

0071880:adenylate cyclase-activating adrenergic receptor signaling pathway

0007186:G protein-coupled receptor signaling pathway

0009986:cell surface

0010700:negative regulation of norepinephrine secretion

0032148:activation of protein kinase B activity

0070474:positive regulation of uterine smooth muscle contraction

0000187:activation of MAPK activity

0043231:intracellular membrane-bounded organelle

0005887:integral component of plasma membrane

0007565:female pregnancy

0003056:regulation of vascular associated smooth muscle contraction

0005829:cytosol

0004938:alpha2-adrenergic receptor activity

0030168:platelet activation

0004930:G protein-coupled receptor activity

0045777:positive regulation of blood pressure

0005886:plasma membrane

0032811:negative regulation of epinephrine secretion

0051379:epinephrine binding

0035624:receptor transactivation

0007267:cell-cell signaling

0045666:positive regulation of neuron differentiation

0071875:adrenergic receptor signaling pathway

PDB 2CVA ; 6K42 ; 6K41
Drugbank DB09205 ; DB09194 ; DB01403 ; DB00540 ; DB00925 ; DB00193 ; DB05461 ; DB00934 ; DB06148 ; DB00502 ; DB01576 ; DB11273 ; DB14185 ; DB00363 ; DB06216 ; DB06707 ; DB00248 ; DB00182 ; DB00734 ; DB00797 ; DB06694 ; DB13345 ; DB05271 ; DB09202 ; DB01175 ; DB01186 ; DB00715 ; DB00589 ; DB00543 ; DB09167 ; DB09229 ; DB04846 ; DB01392 ; DB00668 ; DB01151 ; DB01267 ; DB00217 ; DB00935 ; DB00714 ; DB00408 ; DB00397 ; DB06262 ; DB09304 ; DB06229 ; DB00433 ; DB00246 ; DB13025 ; DB00368 ; DB01136 ; DB04855 ; DB06153 ; DB00292 ; DB00964 ; DB01577 ; DB11124 ; DB00800 ; DB01238 ; DB06678 ; DB01200 ; DB11477 ; DB00268 ; DB00629 ; DB01224 ; DB00575 ; DB01049 ; DB09195 ; DB00457 ; DB01363 ; DB01018 ; DB01365 ; DB00484 ; DB00477 ; DB05492 ; DB11577 ; DB01069 ; DB00697 ; DB11278 ; DB00726
KEGG hsa:151

Related Compounds  (Total: 2)

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C0397
Name: Serotonin
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C0414
Name: Sphingosine


Related Herbs  (Total: 12)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0927 Da Huang Jin Gao大黄浸膏 Medicinal rhubarbRheum officinale
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0928 Da Huang Liu Jin Gao大黄流浸膏 Medicinal rhubarbRheum officinale
H0926 Da Huang大黄 Medicinal rhubarbRheum officinale
H1078 Gan Chan干蟾 NABufo melanostictus
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H0677 Chan Chu蟾蜍 ToadBufo melanostictus
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin