Compound Description
| ID: C0414 | Common name: Sphingosine |
| IUPAC: (E,2S,3R)-2-aminooctadec-4-ene-1,3-diol | CAS: CAS:123-78-4 |
| Chembl ID: CHEMBL67166 | Pubchem ID: CID:5280335 |
| Formula: C18H37NO2 | TCM-ID: TCMC2100 |
| Smiles: CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)N)O | |
| Alias:
4-Octadecene-1,3-diol, 2-amino-, (E)-D-erythro-;
4-Octadecene-1,3-diol, 2-amino-, [R-[R*,S*-(E)]]-; (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol; (-)-D-erythro-Sphingosine; (-)-Sphingosine; (2S,3R)-Sphingosine; (4E)-Sphingenine; 4-Sphingenine; 4-trans-Sphingenine; C18-Sphingosine; D-(+)-erythro-4-trans-Sphingenine; D-Sphingosine; D-erythro-C18-Sphingosine; D-erythro-Sphingosine; Erythrosphingosine; Sphingenine; Sphingosine; erythro-4-Sphingenine; erythro-C18-Sphingosine; trans-4-Sphingenine |
Structure:
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Related Targets (Total: 8)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T71O6U | Ski oncogene | SKI |
P12755 |
A | 2 Reference(s) |
| T95Y0K | Sphingosine kinase 1 | SPHK1 |
Q9NYA1 |
A | 2 Reference(s) |
| T66GX9 | Proline-rich transmembrane protein 2 | PRRT2 |
Q7Z6L0 |
A | 1 Reference(s) |
| T26V6G | G-protein coupled receptor 3 | GPR3 |
P46089 |
A | 1 Reference(s) |
| T03GNH | Alpha-2B adrenergic receptor | ADRA2B |
P18089 |
A | 1 Reference(s) |
| T12CH9 | Sphingosine 1-phosphate receptor 1 | S1PR1 |
P21453 |
A | 1 Reference(s) |
| T52GA6 | Gelsolin | GSN |
P06396 |
B | 1 Reference(s) |
| T05WU9 | Serine/threonine-protein phosphatase 2A activator | PTPA |
Q15257 |
B | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 7)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0004 | Huo Xiang | 藿香 | Patchouli | Pogostemon cablin |
| H0572 | Tu Huo Xiang | 土藿香 | Patchouli | Pogostemon cablin |
| H1120 | Guang Huo Xiang | 广藿香 | Patchouli | Pogostemon cablin |
| H1010 | Du Huo Xiang | 杜藿香 | Patchouli | Pogostemon cablin |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0005 | Huo Xiang Ye | 藿香叶 | Patchouli | Pogostemon cablin |
Ckey description of the interaction between compound and target