Target Description

Type Detail
Target ID T52GA6
Protein Name Gelsolin
Uniprot ID P06396
Protein Name Alias AGEL;  Actin-depolymerizing factor;  ADF;  Brevin
Gene ID 2934
Gene Symbol GSN
Gene Alias NA
TTD T23000: Research target
Pfam PF00626
GO
0007568:aging

0036313:phosphatidylinositol 3-kinase catalytic subunit binding

0003779:actin binding

0030864:cortical actin cytoskeleton

0070062:extracellular exosome

0045159:myosin II binding

0090527:actin filament reorganization

0045335:phagocytic vesicle

0005925:focal adhesion

0097284:hepatocyte apoptotic process

0005829:cytosol

1903906:regulation of plasma membrane raft polarization

1903923:positive regulation of protein processing in phagocytic vesicle

0048015:phosphatidylinositol-mediated signaling

0014891:striated muscle atrophy

2001269:positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

0097017:renal protein absorption

0046597:negative regulation of viral entry into host cell

0055119:relaxation of cardiac muscle

0001726:ruffle

0030478:actin cap

0071801:regulation of podosome assembly

0005737:cytoplasm

0005509:calcium ion binding

0005615:extracellular space

0086003:cardiac muscle cell contraction

0030031:cell projection assembly

0071346:cellular response to interferon-gamma

0010628:positive regulation of gene expression

0030041:actin filament polymerization

0031648:protein destabilization

0005886:plasma membrane

0048471:perinuclear region of cytoplasm

0051593:response to folic acid

1902174:positive regulation of keratinocyte apoptotic process

0051016:barbed-end actin filament capping

0042246:tissue regeneration

0072562:blood microparticle

0030155:regulation of cell adhesion

0002102:podosome

0030042:actin filament depolymerization

0043312:neutrophil degranulation

0042989:sequestering of actin monomers

1990000:amyloid fibril formation

0051693:actin filament capping

0015629:actin cytoskeleton

0043209:myelin sheath

0016528:sarcoplasm

0008154:actin polymerization or depolymerization

0032991:protein-containing complex

0071276:cellular response to cadmium ion

0051014:actin filament severing

0007417:central nervous system development

0006911:phagocytosis, engulfment

0005576:extracellular region

0045471:response to ethanol

0030027:lamellipodium

0035994:response to muscle stretch

0014003:oligodendrocyte development

0051015:actin filament binding

1904813:ficolin-1-rich granule lumen

0034774:secretory granule lumen

0051127:positive regulation of actin nucleation

1903909:regulation of receptor clustering

0042060:wound healing

0045010:actin nucleation

0060271:cilium assembly

1903903:regulation of establishment of T cell polarity

0005546:phosphatidylinositol-4,5-bisphosphate binding

PDB 1DEJ ; 3TU5 ; 5FAF ; 3A5M ; 3A5N ; 2FF6 ; 6QBF ; 4PKH ; 1NM1 ; 1YAG ; 1C0F ; 1H1V ; 2FH4 ; 3A5L ; 4S10 ; 4Z94 ; 5FAE ; 6LJF ; 4PKG ; 6Q9R ; 1T44 ; 6LJE ; 2FH1 ; 3CJB ; 1NLV ; 1C0G ; 3CJC ; 5H3N ; 1YVN ; 6QW3 ; 1P8Z ; 1NMD ; 3FFK ; 3FFN ; 3A5O ; 6Q9Z ; 5ZZ0 ; 6JEH ; 6JEG ; 1P8X ; 5O2Z ; 4PKI ; 1SOL ; 1D4X ; 5DD2 ; 5H3M ; 6JCO ; 2FH2 ; 6H1F ; 1EQY ; 3CIP ; 1ESV ; 1KCQ ; 1MDU ; 2FF3 ; 3CI5 ; 2FH3 ; 5UBO
Drugbank DB01593 ; DB02621 ; DB09130 ; DB14487
KEGG hsa:2934

Related Compounds  (Total: 2)

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C0414
Name: Sphingosine
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C1257
Name: Cotinine


Related Herbs  (Total: 7)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin