Target Description

Type Detail
Target ID T19K8W
Protein Name Signal transducer and activator of transcription 5B
Uniprot ID P51692
Protein Name Alias NA
Gene ID 6777
Gene Symbol STAT5B
Gene Alias NA
TTD T20027: Patented target
Pfam PF00017 ; PF02865 ; PF01017 ; PF02864
GO
0032819:positive regulation of natural killer cell proliferation

0042802:identical protein binding

0005634:nucleus

0035259:glucocorticoid receptor binding

0019915:lipid storage

0038110:interleukin-2-mediated signaling pathway

0097531:mast cell migration

0043434:response to peptide hormone

0038111:interleukin-7-mediated signaling pathway

0005829:cytosol

0045954:positive regulation of natural killer cell mediated cytotoxicity

0042127:regulation of cell population proliferation

0042104:positive regulation of activated T cell proliferation

0071364:cellular response to epidermal growth factor stimulus

0003682:chromatin binding

0040018:positive regulation of multicellular organism growth

0001553:luteinization

0032825:positive regulation of natural killer cell differentiation

0045648:positive regulation of erythrocyte differentiation

0030856:regulation of epithelial cell differentiation

0070670:response to interleukin-4

0046543:development of secondary female sexual characteristics

0005737:cytoplasm

0006952:defense response

0033077:T cell differentiation in thymus

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

0045588:positive regulation of gamma-delta T cell differentiation

0007259:receptor signaling pathway via JAK-STAT

0035723:interleukin-15-mediated signaling pathway

0000785:chromatin

0007595:lactation

0032355:response to estradiol

0032870:cellular response to hormone stimulus

0043066:negative regulation of apoptotic process

0045647:negative regulation of erythrocyte differentiation

0032743:positive regulation of interleukin-2 production

0050729:positive regulation of inflammatory response

0019530:taurine metabolic process

0046983:protein dimerization activity

0045931:positive regulation of mitotic cell cycle

0071363:cellular response to growth factor stimulus

0043029:T cell homeostasis

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0046544:development of secondary male sexual characteristics

0040014:regulation of multicellular organism growth

0060397:growth hormone receptor signaling pathway via JAK-STAT

0003700:DNA-binding transcription factor activity

0042448:progesterone metabolic process

0006357:regulation of transcription by RNA polymerase II

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0005654:nucleoplasm

0038113:interleukin-9-mediated signaling pathway

0007565:female pregnancy

0019221:cytokine-mediated signaling pathway

0045579:positive regulation of B cell differentiation

0045944:positive regulation of transcription by RNA polymerase II

0001779:natural killer cell differentiation

0019218:regulation of steroid metabolic process

0048541:Peyer's patch development

PDB 6MBW ; 6MBZ
Drugbank DB01254
KEGG hsa:6777

Related Compounds  (Total: 8)

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C0263
Name: Oleic Acid
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C0325
Name: Progesterone
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C0397
Name: Serotonin
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C0406
Name: Simvastatin
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C0421
Name: Sulforaphane


Related Herbs  (Total: 179)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0888 Ba Dou Ye巴豆叶 Pu rging crotonCroton tiglium
H0720 Yang Jin Hua洋金花 Hindu datura flowerDatura metel
H0580 Tu Si Rou菟丝肉 Dodder seedCuscuta australis
H0088 Ju He橘核 Tangerine seedCitrus reticulata
H0054 Jin Niu Cao金牛草 NAPolygala glomerata
H1128 Bai Jiang败酱 Whiteflower patriniaPatrinia villosa
H0926 Da Huang大黄 Medicinal rhubarbRheum officinale
H1254 Huang Qin Tan黄芩炭 Extract of root of Baikal skullcaapScutellaria baicalensis
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0581 Tu Si Zi菟丝子 Dodder seedCuscuta australis
H0950 Dan Shen Gan Jin Gao丹参干浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H1164 He Geng荷梗 Hindu lotus petioleNelumbo nucifera
H0524 Tan Xiang檀香 SandalwoodSantalum album
H1156 Ai Di Huang矮地黄 RehmanniaeRehmannia glutinosa
H0576 Tu Mu Xiang土木香 Elecampane inulaInula helenium
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H0697 Ya Ma Zi亚麻子 Common flax seedLinum usitatissimum
H0126 Lai Fu Zi莱菔子 Garden radish seedRaphanus sativus
H0153 Ling Zhi(1)灵芝 Lucid ganodermaGanoderma lucidum
H1251 Huang Qin黄芩 Root of Baikal skullcaapScutellaria baicalensis
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin
H0310 Pian Qin片芩 Scutellaria amoenaScutellaria baicalensis
H0955 Dang Gui当归 Chinese angelicaAngelica sinensis
H0109 Ku Lian Zi苦楝子 NAMelia azedarach
H0383 San Qi Jing Ye三七茎叶 SanchiPanax notoginseng
H1240 Huang Jing Zi黄荆子 NAVitex negundo
H0551 Cang Zhu苍术 Swordlike atractylodesAtractylodes lancea
H0224 Man Tuo Luo Ye曼陀罗叶 Hindu datura leafDatura metel
H0071 Bai Ye柏叶 Chinese arborvitae twigPlatycladus orientalis
H0892 Chuan Xiong川芎 cnidium officinaleCnidium officinale
H0357 Ren Shen人参 GinsengPanax ginseng
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H0079 Jiu Cai韭菜 Tuber onionAllium tuberosum
H0960 Dang Shen Qing Gao党参清膏 Root of hairy asiabellCodonopsis pilosula
H0739 Yi Yi Ren薏苡仁 Jobstears seedCoix lacryma- jobi var. ma - yuen
H0583 Tu Si Zi Teng菟丝子藤 Dodder seedCuscuta australis
H0530 Tao Ren Shuang桃仁霜 Peach kernelPrunus persica
H0740 Yi Zhi益智 Fructus alpinae oxyphyllaeAlpinia oxyphylla
H0016 Ji Xue Cao积雪草 Asiatic pennywortCentella asiatica
H1150 Hai Jin Sha Teng Gan Jin Gao海金沙藤干浸膏 NALygodium japonicum
H0466 Cai Fu Zi菜菔子 Semen raphaniRaphanus sativus
H1051 Bai Guo白果 Ginkgo nutGinkgo biloba
H0108 Ku Lian Pi苦楝皮 Chinaberry-tree barkMelia azedarach
H0301 Ou Hindu lotus large rhizomeNelumbo nucifera
H0853 Zi Wan紫菀 Tatarion asterAster tataricus
H0300 Nv Zhen Zi女贞子 Glossy privet fruitLigustrum lucidum
H0927 Da Huang Jin Gao大黄浸膏 Medicinal rhubarbRheum officinale
H0956 Dang Gui Gan Jin Gao当归干浸膏 NAAngelica sinensis
H0704 Yan Guan Huang Bai盐关黄柏 Amur cork treePhellodendron amurense
H0878 Ba Dou Shuang巴豆霜 Defatted croton seed powderCroton tiglium
H0195 Ma Chi Xian马齿苋 PurslanePortulaca oleracea
H0519 Suo Yang锁阳 Songaria cynomoriumCynomorium songaricum
H1147 Hai Jin Sha海金砂 Japanese climbing fernLygodium japonicum
H0225 Man Tuo Luo Zi曼陀罗子 Hindu datura seedDatura metel
H0104 Bai Zhu白术 Largehead atractylodesAtractylodes macrocephala
H0973 Di Huang Tan地黄炭 RehmanniaeRehmannia glutinosa
H0370 Ru Xiang乳香 OlibanumBoswellia carterii
H0409 Shan Jiang山姜 shell gingerAlpinia zerumbet
H0531 Tao Zhi桃枝 Peach juvenile branchPrunus persica
H0003 Huo Ma Ren火麻仁 Hemp fimble seedCannabis sativa
H0134 Li Zhi He荔枝核 Lychee seedLitchi chinensis
H0816 Chu Ling Dan臭灵丹 laggera pterodontaLaggera pterodonta
H1176 Hei Hu Jiao黑胡椒 Black pepperPiper nigrum
H1169 He Ye荷叶 Hindu lotus leafNelumbo nucifera
H0141 Lian Zi Xin莲子心 Hindu lotus plumuleNelumbo nucifera
H0384 San Qi Ye三七叶 Folium panax notoginsengPanax notoginseng
H0844 Zi Cao紫草 Redroot gromwellLithospermum erythrorhizon
H0527 Tao PeachPrunus persica
H0060 Jin Si Ku Lian金丝苦楝 NACardiospermum halicacabum
H1079 Gan Di Huang干地黄 Adhesive rehmannia dried rootRehmannia glutinosa
H1130 Guang Zao广枣 fruit of axillary choerospondiasFructus choerospondiatis
H1170 He Zi诃子 Medicine terminaliaTerminalia chebula
H0381 San Qi Gao Fen三七膏粉 SanchiPanax notoginseng
H1208 Hu Ma Ren胡麻仁 white seed of oriental sesameSesamum indicum
H0327 Qian Li Guang千里光 Climbing groundselSenecio scandens
H1078 Gan Chan干蟾 NABufo melanostictus
H0771 Yuan Zhi Liu Jin Gao远志流浸膏 Thinleaf milkwortPolygala tenuifolia
H1097 Gong Ding Xiang公丁香 NASyzygium aromaticum
H1252 Huang Qin Jin Gao黄芩浸膏 Extract of root of Baikal skullcaapScutellaria baicalensis
H0743 Yi Zhi Ren益智仁 Sharpleaf galangalAlpinia oxyphylla
H0893 Chuan Xiong Jin Gao川芎浸膏 cnidium officinaleCnidium officinale
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H0416 Shan Shen山参 NAPanax ginseng
H1230 Huang Bai Fen黄柏粉 Amur corktreePhellodendron amurense
H0714 Yan Tai Chai Hu烟台柴胡 Chinese thorowaxBupleurum chinense
H0951 Dan Shen Jin Gao丹参浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0461 Shi Jun Zi Ren使君子仁 NACombretum indicum
H0604 Wu Wei Teng五味藤 NASecuridaca inappendiculata
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0385 San Qi Ye Jing三七叶茎 SanchiPanax notoginseng
H0650 Chai Hu柴胡 Chinese thorowaxBupleurum chinense
H0365 Rou Dou Kou肉豆蔻 Common nutmegMyristica fragrans
H0659 Chai Hu Jin Gao柴胡浸膏 Chinese thorowaxBupleurum chinense
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H1188 Hong Hua红花 SafflowerCarthamus tinctorius
H1214 Hua Jiao花椒 Bunge pricklyashZanthoxylum bungeanum
H0304 Ou Pian藕片 Hindu lotus large rhizomeNelumbo nucifera
H0227 Mang Guo Ye芒果叶 Mango leafMangifera indica
H0382 San Qi Hua三七花 SanchiPanax notoginseng
H0958 Dang Shen党参 Pilose asiabellCodonopsis pilosula
H0002 Hui Xiang茴香 Fennel fruitFoeniculum vulgare
H0302 Ou Fen藕粉 Hindu lotus large rhizomeNelumbo nucifera
H1229 Bai Mu Xiang白木香 Chinese eaglewoodAquilaria sinensis
H1131 Gui Ban龟板 Tortoise plastronPlastrum testudinis
H0928 Da Huang Liu Jin Gao大黄流浸膏 Medicinal rhubarbRheum officinale
H1223 Huai Hun Cao还魂草 NAAster tataricus
H0895 Chuan Yu Jin川郁金 TurmericCurcuma longa
H1148 Hai Jin Sha Cao海金沙草 NALygodium japonicum
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0354 Ren Dong Teng忍冬藤 Japanese honeysuckle vineLonicera japonica
H1253 Huang Qin Jin Gao Fen黄芩浸膏粉 Extract of root of Baikal skullcaapScutellaria baicalensis
H0809 Zhi Mu知母 Common anemarrhenaAnemarrhena asphodeloides
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0897 Chuan Lian川楝 ChinaberryMelia azedarach
H1000 Dong Gua Zi冬瓜子 Chinese waxgourd seedBenincasa hispida
H0093 Ju Pi橘皮 Tangerine pericarpCitrus reticulata
H0665 Chai Hu Shao柴胡梢 Chinese thorowaxBupleurum chinense
H0028 Jiang Huang姜黄 Common turmericCurcuma longa
H0998 Dong Gua Pi冬瓜皮 Chinese waxgourd peelBenincasa hispida
H0750 Yin Xing Ye银杏叶 Folium ginkgoGinkgo biloba
H0217 Man Jing Zi蔓荆子 Threeleaf chastetree fruitVitex trifolia
H0463 Shi Liu Pi石榴皮 Pomegranate peelPunica granatum
H0216 Man Jing Ye蔓荆叶 Threeleaf chastetree leafVitex trifolia
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0473 Shu Di Huang熟地黄 Adhesive rehmannia cocked rootRehmannia glutinosa
H0695 Ya Dan Zi鸦胆子 Java bruceaBrucea javanica
H0057 Jin Sha Teng金沙藤 NALygodium japonicum
H0239 Bei Sha Shen北沙参 Coastal glehniaGlehnia littoralis
H1204 Hu Jiao胡椒 Black pepperPiper nigrum
H1203 Hu Ji Sheng槲寄生 Colored mistletoeViscum coloratum
H0688 Xuan Shen玄参 Ningpo figwortScrophularia ningpoensis
H0515 Suan Shi Liu酸石榴 PomegranatePunica granatum
H0869 Ba Dou巴豆 Pu rging crotonCroton tiglium
H0053 Jin Lian Hua金莲花 Chinese globeflowerTrollius chinensis
H0242 Bei Sha Shen Liu Jin Gao北沙参流浸膏 Glehnia littoralisGlehnia littoralis
H0255 Mao Zhao Cao猫爪草 Root of catclaw buttercupRanunculus ternatus
H0769 Yuan Zhi远志 Thinleaf milkwortPolygala tenuifolia
H0941 Da Zao大枣 Chinese dateZiziphus jujuba
H1181 Hei Zhi Ma黑芝麻 Oriental sesameSesamum indicum
H0529 Tao Ren桃仁 Peach kernelPrunus persica
H0204 Ma Ren麻仁 NACannabis sativa
H1011 Bai Chou白丑 Pharbitis seedSemen pharbitidis
H0990 Ding Xiang丁香 Clove treeSyzygium aromaticum
H0125 Lai Fu莱菔 Garden radishRaphanus sativus
H0258 Mo Han Lian墨旱莲 YerbadetajoEclipta prostrata
H0677 Chan Chu蟾蜍 ToadBufo melanostictus
H0821 Chu Ling Dan Cao臭灵丹草 laggera pterodontaLaggera pterodonta
H0570 Tu Fu Ling土茯苓 Glabrous greenbrierSmilax glabra
H1077 Bai Hu Jiao白胡椒 white pepperPiper nigrum
H0464 Shi Liu Zi石榴子 NAPunica granatum
H0233 Mao Liang Mian Zhen毛两面针 NAZanthoxylum nitidum
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0768 Yuan Shen元参 Figwort rootScrophularia ningpoensis
H1231 Huang Bai Tan黄柏炭 Amur corktreePhellodendron amurense
H1228 Huang Bai黄柏 Amur corktreePhellodendron amurense
H0140 Lian Zi莲子 Hindu lotus seedNelumbo nucifera
H1149 Hai Jin Sha Teng海金沙藤 NALygodium japonicum
H1173 Hei Chou黑丑 Pharbitis seedSemen pharbitidis
H0949 Dan Shen丹参 The root of red-rooted salviaSalvia miltiorrhiza
H1110 Gua Lou Zi瓜蒌子 mongolian snakegourd seedTrichosanthes kirilowii maxim
H0972 Di Huang地黄 RehmanniaeRehmannia glutinosa
H1171 He Zi Rou诃子肉 Medicine terminaliaTerminalia chebula
H1115 Guan Huang Bai关黄柏 Amur cork treePhellodendron amurense
H1055 Bai Guo Ren白果仁 ginkgoGinkgo biloba
H0467 Shi Shang Bai石上柏 Doederlein's spikemoss herbHerba selaginellae doederleinii
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H0547 Cang Qing Guo藏青果 MyrobalanTerminalia chebula
H0484 Shui Fei Ji水飞蓟 St marysSilybum marianum
H0250 Mi Zi Wan蜜紫菀 Tatarian asterAster tataricus
H0462 Shi Liu石榴 Pomegranate fruitPunica granatum
H0380 San Qi Gan Jin Gao三七干浸膏 SanchiPanax notoginseng
H0679 Xing Ren杏仁 Apricot seedPrunus armeniaca
H0770 Yuan Zhi Jin Gao远志浸膏 Thinleaf milkwortPolygala tenuifolia
H0086 Jiu Zi韭子 Tuber onion seedAllium tuberosum
H1207 Hu Ma胡麻 white seed of oriental sesameSesamum indicum
H0152 Ling Zhi Jin Gao灵芝浸膏 NAGanoderma lucidum
H1026 Fan Hun Cao返魂草 Tatarian asterAster tataricus