Herb Description
| Herb ID: H0740 | Chinese Character: 益智 |
| English Name: Fructus alpinae oxyphyllae | Latin Name: Alpinia oxyphylla |
| Chinese Pin Yin : Yi Zhi | TCM-ID: TCMH2488 |
| Therapeutic Function in Chinese : NA | Therapeutic Function in English: NA |
| Herb Function: NA | |
Related Targets (Total: 135)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T02O3F | Endothelial lipase | LIPG |
Q9Y5X9 |
1 Reference(s) |
| T05OGW | Melanoma-associated antigen C3 | MAGEC3 |
Q8TD91 |
1 Reference(s) |
| T30VNV | Myeloperoxidase | MPO |
P05164 |
2 Reference(s) |
| T62P0D | Collagenase 3 | MMP13 |
P45452 |
1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
4 Reference(s) |
| T74WWP | Peroxisome proliferator-activated receptor delta | PPARD |
Q03181 |
1 Reference(s) |
| T14JSX | Plasminogen | PLG |
P00747 |
1 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
4 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
6 Reference(s) |
| T67LRH | RNA-binding protein Musashi homolog 1 | MSI1 |
O43347 |
1 Reference(s) |
| T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
3 Reference(s) |
| T50SJ8 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | PRKAA2 |
P54646 |
2 Reference(s) |
| T88BCB | Glycerol-3-phosphate phosphatase | PGP |
A6NDG6 |
1 Reference(s) |
| T32R5L | Cyclin-dependent kinase 9 | CDK9 |
P50750 |
1 Reference(s) |
| T39M6J | ATP-binding cassette sub-family C member 2 | ABCC2 |
Q92887 |
1 Reference(s) |
| T97FEF | Broad substrate specificity ATP-binding cassette transporter ABCG2 | ABCG2 |
Q9UNQ0 |
1 Reference(s) |
| T74LFK | Neurogenic locus notch homolog protein 1 | NOTCH1 |
P46531 |
1 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
2 Reference(s) |
| T68DAN | Histone deacetylase 9 | HDAC9 |
Q9UKV0 |
1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
4 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
8 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
4 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
4 Reference(s) |
| T90RVD | Histone deacetylase 8 | HDAC8 |
Q9BY41 |
1 Reference(s) |
| T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
2 Reference(s) |
| T09INZ | Transient receptor potential cation channel subfamily A member 1 | TRPA1 |
O75762 |
1 Reference(s) |
| T60XJI | Transient receptor potential cation channel subfamily M member 8 | TRPM8 |
Q7Z2W7 |
3 Reference(s) |
| T67KTV | Transient receptor potential cation channel subfamily V member 1 | TRPV1 |
Q8NER1 |
2 Reference(s) |
| T13KGH | Tyrosinase | TYR |
P14679 |
1 Reference(s) |
| T76AZQ | Histidine decarboxylase | HDC |
P19113 |
1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
2 Reference(s) |
| T13WH4 | Interferon-induced, double-stranded RNA-activated protein kinase | EIF2AK2 |
P19525 |
8 Reference(s) |
| T37G49 | Platelet-activating factor acetylhydrolase | PLA2G7 |
Q13093 |
1 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
1 Reference(s) |
| T68HNO | Glutathione S-transferase omega-1 | GSTO1 |
P78417 |
1 Reference(s) |
| T61LV9 | Free fatty acid receptor 3 | FFAR3 |
O14843 |
1 Reference(s) |
| T76MVQ | Free fatty acid receptor 4 | FFAR4 |
Q5NUL3 |
1 Reference(s) |
| T08U92 | Mitochondrial brown fat uncoupling protein 1 | UCP1 |
P25874 |
1 Reference(s) |
| T75RAR | Dual oxidase 2 | DUOX2 |
Q9NRD8 |
1 Reference(s) |
| T73S71 | Apolipoprotein B-100 | APOB |
P04114 |
2 Reference(s) |
| T99EYH | Lipoprotein lipase | LPL |
P06858 |
1 Reference(s) |
| T80O6V | Hydroxycarboxylic acid receptor 2 | HCAR2 |
Q8TDS4 |
1 Reference(s) |
| T39YFG | Trypsin-1 | PRSS1 |
P07477 |
1 Reference(s) |
| T54WR0 | Fatty acid-binding protein 5 | FABP5 |
Q01469 |
1 Reference(s) |
| T21Q0D | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR |
P04035 |
1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
1 Reference(s) |
| T07S0E | BDNF/NT-3 growth factors receptor | NTRK2 |
Q16620 |
1 Reference(s) |
| T90XYZ | C-reactive protein | CRP |
P02741 |
2 Reference(s) |
| T51WGR | Pancreas/duodenum homeobox protein 1 | PDX1 |
P52945 |
1 Reference(s) |
| T43NBB | Solute carrier family 2, facilitated glucose transporter member 2 | SLC2A2 |
P11168 |
1 Reference(s) |
| T89L4V | Insulin | INS |
P01308 |
1 Reference(s) |
| T38WWN | Serum paraoxonase/arylesterase 1 | PON1 |
P27169 |
1 Reference(s) |
| T23YZF | Peptidyl-glycine alpha-amidating monooxygenase | PAM |
P19021 |
1 Reference(s) |
| T77FOL | Neuromodulin | GAP43 |
P17677 |
1 Reference(s) |
| T93VFT | Endothelin-1 | EDN1 |
P05305 |
2 Reference(s) |
| T36SOV | Plasminogen activator inhibitor 1 | SERPINE1 |
P05121 |
1 Reference(s) |
| T02DEN | Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide | GCG |
P01275 |
2 Reference(s) |
| T48UT8 | Cholesteryl ester transfer protein | CETP |
P11597 |
2 Reference(s) |
| T32HPO | Aspartyl aminopeptidase | DNPEP |
Q9ULA0 |
1 Reference(s) |
| T20H9F | Stromelysin-1 | MMP3 |
P08254 |
1 Reference(s) |
| T02YLA | Alpha-lactalbumin | LALBA |
P00709 |
1 Reference(s) |
| T60GGR | Serine/threonine-protein kinase TBK1 | TBK1 |
Q9UHD2 |
1 Reference(s) |
| T50V79 | Interleukin-4 | IL4 |
P05112 |
1 Reference(s) |
| T50GQE | Interleukin-13 | IL13 |
P35225 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
5 Reference(s) |
| T88LSZ | Aromatase | CYP19A1 |
P11511 |
1 Reference(s) |
| T64W2K | Cyclin-dependent kinase inhibitor 1 | CDKN1A |
P38936 |
1 Reference(s) |
| T18F9A | Glycophorin-B | GYPB |
P06028 |
1 Reference(s) |
| T88HDQ | Tyrosine-protein phosphatase non-receptor type 13 | PTPN13 |
Q12923 |
1 Reference(s) |
| T29MD1 | Mitogen-activated protein kinase 8 | MAPK8 |
P45983 |
1 Reference(s) |
| T39WPZ | Mitogen-activated protein kinase 9 | MAPK9 |
P45984 |
1 Reference(s) |
| T12WTT | Interleukin-5 | IL5 |
P05113 |
1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
4 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
1 Reference(s) |
| T84W8G | Aryl hydrocarbon receptor | AHR |
P35869 |
1 Reference(s) |
| T66FP0 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | PDE4D |
Q08499 |
1 Reference(s) |
| T80XW6 | Scavenger receptor class B member 1 | SCARB1 |
Q8WTV0 |
1 Reference(s) |
| T74JJN | Fatty acid synthase | FASN |
P49327 |
1 Reference(s) |
| T43R3A | TIR domain-containing adapter molecule 2 | TICAM2 |
Q86XR7 |
1 Reference(s) |
| T09GFP | Maltase-glucoamylase, intestinal [Includes: Maltase | MGAM |
O43451 |
1 Reference(s) |
| T38T1U | Caspase-8 | CASP8 |
Q14790 |
1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
3 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
1 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
2 Reference(s) |
| T76TED | Pro-opiomelanocortin | POMC |
P01189 |
1 Reference(s) |
| T37JN5 | Neutrophil gelatinase-associated lipocalin | LCN2 |
P80188 |
1 Reference(s) |
| T17UP9 | C-C motif chemokine 2 | CCL2 |
P13500 |
1 Reference(s) |
| T00H7Q | Neutrophil cytosol factor 1 | NCF1 |
P14598 |
1 Reference(s) |
| T52UTG | Haptoglobin | HP |
P00738 |
1 Reference(s) |
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
1 Reference(s) |
| T93SFQ | NAD-dependent protein deacetylase sirtuin-1 | SIRT1 |
Q96EB6 |
1 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
1 Reference(s) |
| T71BDH | Mitogen-activated protein kinase 14 | MAPK14 |
Q16539 |
1 Reference(s) |
| T95IYZ | Adiponectin | ADIPOQ |
Q15848 |
1 Reference(s) |
| T67RBZ | Mitochondrial uncoupling protein 2 | UCP2 |
P55851 |
2 Reference(s) |
| T67HYX | Mitochondrial uncoupling protein 3 | UCP3 |
P55916 |
1 Reference(s) |
| T19EKF | Cholecystokinin | CCK |
P06307 |
1 Reference(s) |
| T19XSL | Fatty acid-binding protein, liver | FABP1 |
P07148 |
1 Reference(s) |
| T23APZ | Retinol-binding protein 2 | RBP2 |
P50120 |
1 Reference(s) |
| T38K2W | Receptor tyrosine-protein kinase erbB-2 | ERBB2 |
P04626 |
1 Reference(s) |
| T03NWF | Sterol O-acyltransferase 1 | SOAT1 |
P35610 |
1 Reference(s) |
| T48YPL | Aquaporin-3 | AQP3 |
Q92482 |
1 Reference(s) |
| T53SLQ | Aquaporin-9 | AQP9 |
O43315 |
1 Reference(s) |
| T75EH8 | Glucagon-like peptide 1 receptor | GLP1R |
P43220 |
1 Reference(s) |
| T52VL6 | Signal transducer and activator of transcription 5A | STAT5A |
P42229 |
1 Reference(s) |
| T19K8W | Signal transducer and activator of transcription 5B | STAT5B |
P51692 |
1 Reference(s) |
| T01D27 | Eukaryotic translation initiation factor 6 | EIF6 |
P56537 |
1 Reference(s) |
| T09S1E | Tumor necrosis factor alpha-induced protein 3 | TNFAIP3 |
P21580 |
1 Reference(s) |
| T09BRP | NA | PKB_RS07820 |
NA |
1 Reference(s) |
| T87QUW | Actin, aortic smooth muscle | ACTA2 |
P62736 |
1 Reference(s) |
| T52H3P | Claudin-1 | CLDN1 |
O95832 |
1 Reference(s) |
| T75KZ8 | Claudin-11 | CLDN11 |
O75508 |
1 Reference(s) |
| T91OUC | Mucin-5AC | MUC5AC |
P98088 |
1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
1 Reference(s) |
| T70HC9 | Hepatocyte nuclear factor 1-alpha | HNF1A |
P20823 |
1 Reference(s) |
| T49J7I | Hepatocyte nuclear factor 4-alpha | HNF4A |
P41235 |
1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
1 Reference(s) |
| T14ENF | Microtubule-associated protein 2 | MAP2 |
P11137 |
1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
2 Reference(s) |
| T98DNG | Natriuretic peptides A | NPPA |
P01160 |
1 Reference(s) |
| T78ILO | Stearoyl-CoA desaturase | SCD |
O00767 |
1 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
1 Reference(s) |
| T68IZC | Natriuretic peptides B | NPPB |
P16860 |
1 Reference(s) |
| T02H9U | Nuclear factor of activated T-cells, cytoplasmic 4 | NFATC4 |
Q14934 |
1 Reference(s) |
| T53YWQ | Pro-neuropeptide Y [Cleaved into: Neuropeptide Y | NPY |
P01303 |
1 Reference(s) |
| T70SFS | Superoxide dismutase [Mn], mitochondrial | SOD2 |
P04179 |
1 Reference(s) |
| T30D9G | Superoxide dismutase [Cu-Zn] | SOD1 |
P00441 |
1 Reference(s) |
| T96YED | Integrin-linked protein kinase | ILK |
Q13418 |
1 Reference(s) |
| T02WMA | Ornithine decarboxylase | ODC1 |
P11926 |
2 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
1 Reference(s) |
| T24U57 | E-selectin | SELE |
P16581 |
1 Reference(s) |
| T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
1 Reference(s) |
Related Compounds (Total: 19)
C0245
Name: Niacin
C0263
Name: Oleic Acid
C0252
Name: Nootkatone
C1237
Name: Chrysin
C0063
Name: Eucalyptol
key description of the interaction between compound and target