Target Description
| Type | Detail |
|---|---|
| Target ID | T80O6V |
| Protein Name | Hydroxycarboxylic acid receptor 2 |
| Uniprot ID |
Q8TDS4 |
| Protein Name Alias | G-protein coupled receptor 109A; G-protein coupled receptor HM74A; Niacin receptor 1; Nicotinic acid receptor |
| Gene ID |
338442 |
| Gene Symbol | HCAR2 |
| Gene Alias | GPR109A; HCA2; HM74A; NIACR1 |
| TTD | T88185: Successful target |
| Pfam | PF00001 |
| GO |
0070165:positive regulation of adiponectin secretion
0001781:neutrophil apoptotic process 0016021:integral component of membrane 0030054:cell junction 0070553:nicotinic acid receptor activity 0050995:negative regulation of lipid catabolic process 0033031:positive regulation of neutrophil apoptotic process 0005886:plasma membrane 0007186:G protein-coupled receptor signaling pathway |
| PDB | NA |
| Drugbank | DB08949 ; DB00257 ; DB00627 |
| KEGG | hsa:338442 |
Related Herbs (Total: 58)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0809 | Zhi Mu | 知母 | Common anemarrhena | Anemarrhena asphodeloides |
| H0846 | Chou Wu Tong Ye | 臭梧桐叶 | Harlequin glorybower | Clerodendrum trichotomum |
| H0743 | Yi Zhi Ren | 益智仁 | Sharpleaf galangal | Alpinia oxyphylla |
| H0189 | Lv Cha | 绿茶 | Green tea | Folium camelliae sinensis |
| H0209 | Ma You | 麻油 | Sesame oil | Oleum sesami |
| H0423 | Shan Zha Ye | 山楂叶 | NA | Crataegi folium |
| H0834 | Chu Shi Zi | 楮实子 | common papermulberry fruit | Fructus broussonetiae |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0271 | Mu Ji | 母鸡 | Hen | Gallus domesticus |
| H0657 | Xiao Che Qian | 小车前 | all-grass of little plantain | Herba plantaginis minutae |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H0747 | An Xi Xiang | 安息香 | Sumatra snowbel | Styrax benzoin |
| H1205 | Hu Lu Cha | 葫芦茶 | Triquetrous tadehagi | Tadehagi triquetrum |
| H0161 | Long Chi | 龙齿 | dens draconis fossilia dragon's teeth | Dens draconis |
| H0811 | Zhi Quan Xie | 炙全蝎 | Prepared scorpion | Scorpio preparata |
| H0999 | Dong Gua Ren | 冬瓜仁 | Seed of chinese waxgourd | Semen benincasae |
| H0094 | Gou Qi | 枸杞 | Chinese wolfberry fruit | Lycium chinense |
| H0109 | Ku Lian Zi | 苦楝子 | NA | Melia azedarach |
| H0740 | Yi Zhi | 益智 | Fructus alpinae oxyphyllae | Alpinia oxyphylla |
| H0479 | Shu Qu Cao | 鼠曲草 | Cudweed | Gnaphalium affine |
| H1004 | Bai Cha | 白茶 | White tea | Camellia sinensis |
| H0748 | Chen Xiao Mai Fen | 陈小麦粉 | Wheat | Triticum aestivum |
| H1181 | Hei Zhi Ma | 黑芝麻 | Oriental sesame | Sesamum indicum |
| H0371 | Rui Ren | 蕤仁 | Hedge prinsepia nut | Nux prinsepiae |
| H0279 | Nan Gua | 南瓜 | Cushaw | Cucurbita moschata |
| H0666 | Xiao Mai | 小麦 | Wheat | Triticum aestivum |
| H0995 | Dong Chong Xia Cao | 冬虫夏草 | Aweto | Cordyceps sinensis |
| H0108 | Ku Lian Pi | 苦楝皮 | Chinaberry-tree bark | Melia azedarach |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H0637 | Cha Ye | 茶叶 | Common tea | Camellia sinensis |
| H0133 | Li Yu | 鲤鱼 | Carp | Cyprinus carpio |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0841 | Chou Wu Tong | 臭梧桐 | Harlequin glorybower | Clerodendrum trichotomum |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0808 | Zhi Ma You | 芝麻油 | oil of oriental sesame | Oleum sesami |
| H0897 | Chuan Lian | 川楝 | Chinaberry | Melia azedarach |
| H1208 | Hu Ma Ren | 胡麻仁 | white seed of oriental sesame | Sesamum indicum |
| H0566 | Cao Cong Rong | 草苁蓉 | Russian boschniakia | Boschniakia rossica |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H0215 | Mai Ya | 麦芽 | Barley germinating fruit | Hordeum vulgare |
| H0095 | Gou Qi Zi | 枸杞子 | Chinese wolfberry fruit | Lycium chinense |
| H0830 | Chu Shi | 楮实 | Papermulberry fruit | Fructus broussonetiae |
| H0958 | Dang Shen | 党参 | Pilose asiabell | Codonopsis pilosula |
| H0305 | Ou Tan | 藕炭 | Prepared node of lotus rhizome | Nelumbinis rhizomatis preparata |
| H0960 | Dang Shen Qing Gao | 党参清膏 | Root of hairy asiabell | Codonopsis pilosula |
| H0099 | Ju Zi Xiang Jing | 橘子香精 | Aurantium oil | Oleum aurantii |
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H1000 | Dong Gua Zi | 冬瓜子 | Chinese waxgourd seed | Benincasa hispida |
| H1207 | Hu Ma | 胡麻 | white seed of oriental sesame | Sesamum indicum |
| H0596 | Wu Ji | 乌鸡 | Black chicken | Gallus domesticus |
| H0275 | Mu Zei | 木贼 | Common scouring rush | Equisetum hiemale |
| H0840 | An You | 按油 | Eucalyptus oil | Oleum eucalypti |
| H1029 | Fang Er Cha | 方儿茶 | khair in hindi | Senegalia catechu |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H1052 | Fu Fang Teng | 扶芳藤 | Forture euonymus | Euonymus fortunei |
| H0755 | Ying Shan Hong | 映山红 | Korean rhododendron | Rhododendron mucronulatum |
| H0998 | Dong Gua Pi | 冬瓜皮 | Chinese waxgourd peel | Benincasa hispida |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |