Compound Description
| ID: C0245 | Common name: Niacin |
| IUPAC: pyridine-3-carboxylic acid | CAS: CAS:59-67-6 |
| Chembl ID: CHEMBL573 | Pubchem ID: CID:938 |
| Formula: C6H5NO2 | TCM-ID: TCMC1741 |
| Smiles: C1=CC(=CN=C1)C(=O)O | |
| Alias:
Nicotinic acid;
3-Carboxylpyridine; 3-Carboxypyridine; 3-Pyridylcarboxylic acid; Akotin; Apelagrin; Bovi-Niacin; CaRo 03; Daskil; Disperse NNO; E 375; Efacin; Enduracin; Linic; Microvit B3 Promix Niacin; NSC 169454; NiaShure; Niac; Niacin; Niacor; Niaspan; Nicacid; Nicangin; Nico-Span; Nicobid; Nicodelmine; Nicolar; Niconacid; Nicosan 3; Nicotinipca; Nicyl; Nyclin; Pellagrin; Pelonin; Pyridine-3-carboxylic acid; SR 4390; Slo-niacin; Vitamin B3; Vitamin B3 (niacin); Vitamin B3 (nicotinic acid); Vitamin B5; Wampocap; β-Pyridinecarboxylic acid |
Structure:
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Related Targets (Total: 13)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T02O3F | Endothelial lipase | LIPG |
Q9Y5X9 |
A | 1 Reference(s) |
| T05OGW | Melanoma-associated antigen C3 | MAGEC3 |
Q8TD91 |
A | 1 Reference(s) |
| T73S71 | Apolipoprotein B-100 | APOB |
P04114 |
B | 2 Reference(s) |
| T99EYH | Lipoprotein lipase | LPL |
P06858 |
B | 1 Reference(s) |
| T80O6V | Hydroxycarboxylic acid receptor 2 | HCAR2 |
Q8TDS4 |
B | 1 Reference(s) |
| T67KTV | Transient receptor potential cation channel subfamily V member 1 | TRPV1 |
Q8NER1 |
B | 1 Reference(s) |
| T52UTG | Haptoglobin | HP |
P00738 |
C | 1 Reference(s) |
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
C | 1 Reference(s) |
| T93SFQ | NAD-dependent protein deacetylase sirtuin-1 | SIRT1 |
Q96EB6 |
C | 1 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
C | 1 Reference(s) |
| T71BDH | Mitogen-activated protein kinase 14 | MAPK14 |
Q16539 |
C | 1 Reference(s) |
| T95IYZ | Adiponectin | ADIPOQ |
Q15848 |
C | 1 Reference(s) |
| T48UT8 | Cholesteryl ester transfer protein | CETP |
P11597 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 56)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0133 | Li Yu | 鲤鱼 | Carp | Cyprinus carpio |
| H0566 | Cao Cong Rong | 草苁蓉 | Russian boschniakia | Boschniakia rossica |
| H0740 | Yi Zhi | 益智 | Fructus alpinae oxyphyllae | Alpinia oxyphylla |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H0841 | Chou Wu Tong | 臭梧桐 | Harlequin glorybower | Clerodendrum trichotomum |
| H1207 | Hu Ma | 胡麻 | white seed of oriental sesame | Sesamum indicum |
| H1208 | Hu Ma Ren | 胡麻仁 | white seed of oriental sesame | Sesamum indicum |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H0666 | Xiao Mai | 小麦 | Wheat | Triticum aestivum |
| H0189 | Lv Cha | 绿茶 | Green tea | Folium camelliae sinensis |
| H0808 | Zhi Ma You | 芝麻油 | oil of oriental sesame | Oleum sesami |
| H0743 | Yi Zhi Ren | 益智仁 | Sharpleaf galangal | Alpinia oxyphylla |
| H0995 | Dong Chong Xia Cao | 冬虫夏草 | Aweto | Cordyceps sinensis |
| H0209 | Ma You | 麻油 | Sesame oil | Oleum sesami |
| H0108 | Ku Lian Pi | 苦楝皮 | Chinaberry-tree bark | Melia azedarach |
| H0279 | Nan Gua | 南瓜 | Cushaw | Cucurbita moschata |
| H0657 | Xiao Che Qian | 小车前 | all-grass of little plantain | Herba plantaginis minutae |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0897 | Chuan Lian | 川楝 | Chinaberry | Melia azedarach |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0748 | Chen Xiao Mai Fen | 陈小麦粉 | Wheat | Triticum aestivum |
| H0305 | Ou Tan | 藕炭 | Prepared node of lotus rhizome | Nelumbinis rhizomatis preparata |
| H0423 | Shan Zha Ye | 山楂叶 | NA | Crataegi folium |
| H0099 | Ju Zi Xiang Jing | 橘子香精 | Aurantium oil | Oleum aurantii |
| H0958 | Dang Shen | 党参 | Pilose asiabell | Codonopsis pilosula |
| H1205 | Hu Lu Cha | 葫芦茶 | Triquetrous tadehagi | Tadehagi triquetrum |
| H0999 | Dong Gua Ren | 冬瓜仁 | Seed of chinese waxgourd | Semen benincasae |
| H0094 | Gou Qi | 枸杞 | Chinese wolfberry fruit | Lycium chinense |
| H1029 | Fang Er Cha | 方儿茶 | khair in hindi | Senegalia catechu |
| H0834 | Chu Shi Zi | 楮实子 | common papermulberry fruit | Fructus broussonetiae |
| H0271 | Mu Ji | 母鸡 | Hen | Gallus domesticus |
| H0809 | Zhi Mu | 知母 | Common anemarrhena | Anemarrhena asphodeloides |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0840 | An You | 按油 | Eucalyptus oil | Oleum eucalypti |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |
| H0830 | Chu Shi | 楮实 | Papermulberry fruit | Fructus broussonetiae |
| H0811 | Zhi Quan Xie | 炙全蝎 | Prepared scorpion | Scorpio preparata |
| H0095 | Gou Qi Zi | 枸杞子 | Chinese wolfberry fruit | Lycium chinense |
| H0755 | Ying Shan Hong | 映山红 | Korean rhododendron | Rhododendron mucronulatum |
| H1181 | Hei Zhi Ma | 黑芝麻 | Oriental sesame | Sesamum indicum |
| H0371 | Rui Ren | 蕤仁 | Hedge prinsepia nut | Nux prinsepiae |
| H0161 | Long Chi | 龙齿 | dens draconis fossilia dragon's teeth | Dens draconis |
| H0960 | Dang Shen Qing Gao | 党参清膏 | Root of hairy asiabell | Codonopsis pilosula |
| H1000 | Dong Gua Zi | 冬瓜子 | Chinese waxgourd seed | Benincasa hispida |
| H0596 | Wu Ji | 乌鸡 | Black chicken | Gallus domesticus |
| H1052 | Fu Fang Teng | 扶芳藤 | Forture euonymus | Euonymus fortunei |
| H1004 | Bai Cha | 白茶 | White tea | Camellia sinensis |
| H0215 | Mai Ya | 麦芽 | Barley germinating fruit | Hordeum vulgare |
| H0109 | Ku Lian Zi | 苦楝子 | NA | Melia azedarach |
| H0637 | Cha Ye | 茶叶 | Common tea | Camellia sinensis |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H0846 | Chou Wu Tong Ye | 臭梧桐叶 | Harlequin glorybower | Clerodendrum trichotomum |
| H0998 | Dong Gua Pi | 冬瓜皮 | Chinese waxgourd peel | Benincasa hispida |
| H0479 | Shu Qu Cao | 鼠曲草 | Cudweed | Gnaphalium affine |
Ckey description of the interaction between compound and target