HIT-result

ID: C0252	Common name: Nootkatone
IUPAC: (4R,4aS,6R)-4,4a-dimethyl-6-prop-1-en-2-yl-3,4,5,6,7,8-hexahydronaphthalen-2-one	CAS: CAS:4674-50-4
Chembl ID: CHEMBL446299	Pubchem ID: CID:1268142
Formula: C15H22O	TCM-ID: TCMC1752
Smiles: O=C1C[C@@H](C)[C@]2(C(=C1)CC[C@H](C2)C(=C)C)C
Alias: 2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-4,4a-dimethyl-6-(1-methylethenyl)-, [4R-(4α,4aα,6β)]-; 4βH,5α-Eremophila-1(10),11-dien-2-one; Nootkatone; (4R,4aS,6R)-4,4a,5,6,7,8-Hexahydro-4,4a-dimethyl-6-(1-methylethenyl)-2(3H)-naphthalenone; (+)-Nootkatone; (4R,4AS,6R)-4,4a-dimethyl-6-(prop-1-en-2-yl)-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one; Nootkanone	Structure:

Target id	Protein Name	Gene Symbol	Uniprot ID	Target Level	No.of Literature Evidence
T81I4T	5'-AMP-activated protein kinase catalytic subunit alpha-1	PRKAA1	Q13131	A	2 Reference(s)
T50SJ8	5'-AMP-activated protein kinase catalytic subunit alpha-2	PRKAA2	P54646	A	1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0652	Xiang Yuan Pi	香橼皮	Wilson citron	Citrus medica
H0740	Yi Zhi	益智	Fructus alpinae oxyphyllae	Alpinia oxyphylla
H0193	Ma Bian Cao	马鞭草	European verbena	Verbena officinalis
H0651	Xiang Yuan	香橼	Wilson citron	Citrus medica
H0576	Tu Mu Xiang	土木香	Elecampane inula	Inula helenium
H0409	Shan Jiang	山姜	shell ginger	Alpinia zerumbet
H0640	Xiang Fu	香附	Nutgrass galingale	Cyperus rotundus
H0743	Yi Zhi Ren	益智仁	Sharpleaf galangal	Alpinia oxyphylla

Compound Description

Related Targets (Total: 2)

Related Herbs (Total: 8)