Target Description

Type Detail
Target ID T96YED
Protein Name Integrin-linked protein kinase
Uniprot ID Q13418
Protein Name Alias EC 2.7.11.1;  59 kDa serine/threonine-protein kinase;  Beta-integrin-linked kinase;  ILK-1;  ILK-2;  p59ILK
Gene ID 3611
Gene Symbol ILK
Gene Alias ILK1;  ILK2
TTD T13616: Patented target
Pfam PF12796 ; PF07714
GO
0000902:cell morphogenesis

0004672:protein kinase activity

0005925:focal adhesion

0106310:protein serine kinase activity

0004674:protein serine/threonine kinase activity

1901224:positive regulation of NIK/NF-kappaB signaling

0106311:protein threonine kinase activity

0042327:positive regulation of phosphorylation

0034446:substrate adhesion-dependent cell spreading

0007160:cell-matrix adhesion

0030017:sarcomere

0019901:protein kinase binding

0005829:cytosol

0005524:ATP binding

0001934:positive regulation of protein phosphorylation

0005886:plasma membrane

0016020:membrane

0070527:platelet aggregation

0007229:integrin-mediated signaling pathway

0006468:protein phosphorylation

0045893:positive regulation of transcription, DNA-templated

0034329:cell junction assembly

1900026:positive regulation of substrate adhesion-dependent cell spreading

0030027:lamellipodium

0009967:positive regulation of signal transduction

0033209:tumor necrosis factor-mediated signaling pathway

0005654:nucleoplasm

0090263:positive regulation of canonical Wnt signaling pathway

PDB 2KBX ; 4HI9 ; 3IXE ; 3KMU ; 3KMW ; 6MIB ; 4HI8 ; 3REP ; 3F6Q
Drugbank NA
KEGG hsa:3611

Related Compounds  (Total: 2)

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C0138
Name: Icosapent
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C0213
Name: Metformin


Related Herbs  (Total: 6)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0743 Yi Zhi Ren益智仁 Sharpleaf galangalAlpinia oxyphylla
H0740 Yi Zhi益智 Fructus alpinae oxyphyllaeAlpinia oxyphylla
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0088 Ju He橘核 Tangerine seedCitrus reticulata
H0093 Ju Pi橘皮 Tangerine pericarpCitrus reticulata