HIT-result

Type	Detail
Target ID	T96YED
Protein Name	Integrin-linked protein kinase
Uniprot ID	Q13418
Protein Name Alias	EC 2.7.11.1; 59 kDa serine/threonine-protein kinase; Beta-integrin-linked kinase; ILK-1; ILK-2; p59ILK
Gene ID	3611
Gene Symbol	ILK
Gene Alias	ILK1; ILK2
TTD	T13616: Patented target
Pfam	PF12796 ; PF07714
GO	0000902:cell morphogenesis 0004672:protein kinase activity 0005925:focal adhesion 0106310:protein serine kinase activity 0004674:protein serine/threonine kinase activity 1901224:positive regulation of NIK/NF-kappaB signaling 0106311:protein threonine kinase activity 0042327:positive regulation of phosphorylation 0034446:substrate adhesion-dependent cell spreading 0007160:cell-matrix adhesion 0030017:sarcomere 0019901:protein kinase binding 0005829:cytosol 0005524:ATP binding 0001934:positive regulation of protein phosphorylation 0005886:plasma membrane 0016020:membrane 0070527:platelet aggregation 0007229:integrin-mediated signaling pathway 0006468:protein phosphorylation 0045893:positive regulation of transcription, DNA-templated 0034329:cell junction assembly 1900026:positive regulation of substrate adhesion-dependent cell spreading 0030027:lamellipodium 0009967:positive regulation of signal transduction 0033209:tumor necrosis factor-mediated signaling pathway 0005654:nucleoplasm 0090263:positive regulation of canonical Wnt signaling pathway
PDB	2KBX ; 4HI9 ; 3IXE ; 3KMU ; 3KMW ; 6MIB ; 4HI8 ; 3REP ; 3F6Q
Drugbank	NA
KEGG	hsa:3611

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Name: Metformin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0740	Yi Zhi	益智	Fructus alpinae oxyphyllae	Alpinia oxyphylla
H0088	Ju He	橘核	Tangerine seed	Citrus reticulata
H0093	Ju Pi	橘皮	Tangerine pericarp	Citrus reticulata
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0743	Yi Zhi Ren	益智仁	Sharpleaf galangal	Alpinia oxyphylla