Herb Description

Herb ID:   H0769 Chinese Character:   远志
English Name:  Thinleaf milkwort Latin Name:  Polygala tenuifolia
Chinese Pin Yin :  Yuan Zhi TCM-ID:  TCMH2554
Therapeutic Function in Chinese :  安神 Therapeutic Function in English:  Spirit calming
Herb Function:  Calm the heart and soothe the mind, resolve phlegm and clear the orifices (sense organs)

Related Targets  (Total: 86)

Target idProtein NameGene SymbolUniprot IDNo.of Literature Evidence
T22NX4 Toll-like receptor 2TLR2 O60603
1 Reference(s)
T76QBQ CREB-regulated transcription coactivator 2CRTC2 Q53ET0
1 Reference(s)
T58XLK Tyrosine-protein phosphatase non-receptor type 1PTPN1 P18031
2 Reference(s)
T77PFO Histone deacetylase 6HDAC6 Q9UBN7
1 Reference(s)
T30VNV MyeloperoxidaseMPO P05164
1 Reference(s)
T62P0D Collagenase 3MMP13 P45452
1 Reference(s)
T09H2Z Nitric oxide synthase, inducibleNOS2 P35228
2 Reference(s)
T74WWP Peroxisome proliferator-activated receptor deltaPPARD Q03181
1 Reference(s)
T14JSX PlasminogenPLG P00747
1 Reference(s)
T49ORJ Peroxisome proliferator-activated receptor alphaPPARA Q07869
5 Reference(s)
T58J2Y Peroxisome proliferator-activated receptor gammaPPARG P37231
1 Reference(s)
T67LRH RNA-binding protein Musashi homolog 1MSI1 O43347
1 Reference(s)
T37G49 Platelet-activating factor acetylhydrolasePLA2G7 Q13093
1 Reference(s)
T92FAW Dual specificity protein phosphatase 1DUSP1 P28562
1 Reference(s)
T82S6C Hexokinase-4GCK P35557
1 Reference(s)
T50WOV ATP-dependent translocase ABCB1ABCB1 P08183
1 Reference(s)
T39YFG Trypsin-1PRSS1 P07477
1 Reference(s)
T54WR0 Fatty acid-binding protein 5FABP5 Q01469
1 Reference(s)
T21Q0D 3-hydroxy-3-methylglutaryl-coenzyme A reductaseHMGCR P04035
1 Reference(s)
T12T4H Brain-derived neurotrophic factorBDNF P23560
2 Reference(s)
T07S0E BDNF/NT-3 growth factors receptorNTRK2 Q16620
1 Reference(s)
T90XYZ C-reactive proteinCRP P02741
1 Reference(s)
T51WGR Pancreas/duodenum homeobox protein 1PDX1 P52945
1 Reference(s)
T43NBB Solute carrier family 2, facilitated glucose transporter member 2SLC2A2 P11168
1 Reference(s)
T89L4V InsulinINS P01308
1 Reference(s)
T38WWN Serum paraoxonase/arylesterase 1PON1 P27169
1 Reference(s)
T23YZF Peptidyl-glycine alpha-amidating monooxygenasePAM P19021
1 Reference(s)
T77FOL NeuromodulinGAP43 P17677
1 Reference(s)
T93VFT Endothelin-1EDN1 P05305
1 Reference(s)
T36SOV Plasminogen activator inhibitor 1SERPINE1 P05121
1 Reference(s)
T02DEN Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptideGCG P01275
1 Reference(s)
T48UT8 Cholesteryl ester transfer proteinCETP P11597
1 Reference(s)
T32HPO Aspartyl aminopeptidaseDNPEP Q9ULA0
1 Reference(s)
T20H9F Stromelysin-1MMP3 P08254
1 Reference(s)
T02YLA Alpha-lactalbuminLALBA P00709
1 Reference(s)
T76TED Pro-opiomelanocortinPOMC P01189
1 Reference(s)
T37JN5 Neutrophil gelatinase-associated lipocalinLCN2 P80188
1 Reference(s)
T17UP9 C-C motif chemokine 2CCL2 P13500
1 Reference(s)
T69NG6 Interleukin-10IL10 P22301
1 Reference(s)
T23VMI Tumor necrosis factorTNF P01375
1 Reference(s)
T51EKP Apolipoprotein MAPOM O95445
1 Reference(s)
T07VV7 GuanylinGUCA2A Q02747
1 Reference(s)
T67ZT3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENPTEN P60484
1 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
5 Reference(s)
T80WPU Protein ABHD15ABHD15 Q6UXT9
1 Reference(s)
T56OUM 14-3-3 protein zeta/deltaYWHAZ P63104
1 Reference(s)
T24YWQ Insulin-degrading enzymeIDE P14735
1 Reference(s)
T34HYH Interleukin-1 alphaIL1A P01583
1 Reference(s)
T04V7K Ectonucleotide pyrophosphatase/phosphodiesterase family member 7ENPP7 Q6UWV6
1 Reference(s)
T51U9M Carnitine O-palmitoyltransferase 1, muscle isoformCPT1B Q92523
1 Reference(s)
T07TMB Cyclin-dependent kinase 1CDK1 P06493
1 Reference(s)
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
1 Reference(s)
T42D4V Histone deacetylase 1HDAC1 Q13547
1 Reference(s)
T67RBZ Mitochondrial uncoupling protein 2UCP2 P55851
1 Reference(s)
T67HYX Mitochondrial uncoupling protein 3UCP3 P55916
1 Reference(s)
T19EKF CholecystokininCCK P06307
1 Reference(s)
T19XSL Fatty acid-binding protein, liverFABP1 P07148
1 Reference(s)
T23APZ Retinol-binding protein 2RBP2 P50120
1 Reference(s)
T38K2W Receptor tyrosine-protein kinase erbB-2ERBB2 P04626
1 Reference(s)
T03NWF Sterol O-acyltransferase 1SOAT1 P35610
1 Reference(s)
T48YPL Aquaporin-3AQP3 Q92482
1 Reference(s)
T53SLQ Aquaporin-9AQP9 O43315
1 Reference(s)
T75EH8 Glucagon-like peptide 1 receptorGLP1R P43220
1 Reference(s)
T52VL6 Signal transducer and activator of transcription 5ASTAT5A P42229
1 Reference(s)
T19K8W Signal transducer and activator of transcription 5BSTAT5B P51692
1 Reference(s)
T18DUA Tight junction protein ZO-1TJP1 Q07157
1 Reference(s)
T10HL8 Intercellular adhesion molecule 1ICAM1 P05362
1 Reference(s)
T98DNG Natriuretic peptides ANPPA P01160
1 Reference(s)
T78ILO Stearoyl-CoA desaturaseSCD O00767
1 Reference(s)
T63GUB Proto-oncogene c-FosFOS P01100
2 Reference(s)
T68IZC Natriuretic peptides BNPPB P16860
1 Reference(s)
T06RMZ Nuclear factor NF-kappa-B p105 subunitNFKB1 P19838
2 Reference(s)
T26KIE Transcription factor AP-1JUN P05412
1 Reference(s)
T02H9U Nuclear factor of activated T-cells, cytoplasmic 4NFATC4 Q14934
1 Reference(s)
T49PL1 Low-density lipoprotein receptorLDLR P01130
1 Reference(s)
T57RCH Glutamate decarboxylase 2GAD2 Q05329
1 Reference(s)
T40JZG GPI-anchor transamidasePIGK Q92643
1 Reference(s)
T29MD1 Mitogen-activated protein kinase 8MAPK8 P45983
2 Reference(s)
T82JWE Cellular tumor antigen p53TP53 P04637
3 Reference(s)
T58CAO Alpha-synucleinSNCA P37840
1 Reference(s)
T38J3Y Gamma-enolaseENO2 P09104
1 Reference(s)
T57FUN Beclin-1BECN1 Q14457
1 Reference(s)
T95EK6 Microtubule-associated proteins 1A/1B light chain 3BMAP1LC3B Q9GZQ8
1 Reference(s)
T67HXL Glial cell line-derived neurotrophic factorGDNF P39905
1 Reference(s)
T91IWA Ciliary neurotrophic factorCNTF P26441
1 Reference(s)
T18CPB Choline O-acetyltransferaseCHAT P28329
1 Reference(s)

Related Compounds  (Total: 10)

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C0285
Name: Palmitic Acid
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C0416
Name: Stearic Acid
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C0219
Name: Methyleugenol
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C0263
Name: Oleic Acid
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C0453
Name: Trans-Asarone