HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T22NX4	Toll-like receptor 2	TLR2	O60603	1 Reference(s)
T76QBQ	CREB-regulated transcription coactivator 2	CRTC2	Q53ET0	1 Reference(s)
T58XLK	Tyrosine-protein phosphatase non-receptor type 1	PTPN1	P18031	2 Reference(s)
T77PFO	Histone deacetylase 6	HDAC6	Q9UBN7	1 Reference(s)
T30VNV	Myeloperoxidase	MPO	P05164	1 Reference(s)
T62P0D	Collagenase 3	MMP13	P45452	1 Reference(s)
T09H2Z	Nitric oxide synthase, inducible	NOS2	P35228	2 Reference(s)
T74WWP	Peroxisome proliferator-activated receptor delta	PPARD	Q03181	1 Reference(s)
T14JSX	Plasminogen	PLG	P00747	1 Reference(s)
T49ORJ	Peroxisome proliferator-activated receptor alpha	PPARA	Q07869	5 Reference(s)
T58J2Y	Peroxisome proliferator-activated receptor gamma	PPARG	P37231	1 Reference(s)
T67LRH	RNA-binding protein Musashi homolog 1	MSI1	O43347	1 Reference(s)
T37G49	Platelet-activating factor acetylhydrolase	PLA2G7	Q13093	1 Reference(s)
T92FAW	Dual specificity protein phosphatase 1	DUSP1	P28562	1 Reference(s)
T82S6C	Hexokinase-4	GCK	P35557	1 Reference(s)
T50WOV	ATP-dependent translocase ABCB1	ABCB1	P08183	1 Reference(s)
T39YFG	Trypsin-1	PRSS1	P07477	1 Reference(s)
T54WR0	Fatty acid-binding protein 5	FABP5	Q01469	1 Reference(s)
T21Q0D	3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMGCR	P04035	1 Reference(s)
T12T4H	Brain-derived neurotrophic factor	BDNF	P23560	2 Reference(s)
T07S0E	BDNF/NT-3 growth factors receptor	NTRK2	Q16620	1 Reference(s)
T90XYZ	C-reactive protein	CRP	P02741	1 Reference(s)
T51WGR	Pancreas/duodenum homeobox protein 1	PDX1	P52945	1 Reference(s)
T43NBB	Solute carrier family 2, facilitated glucose transporter member 2	SLC2A2	P11168	1 Reference(s)
T89L4V	Insulin	INS	P01308	1 Reference(s)
T38WWN	Serum paraoxonase/arylesterase 1	PON1	P27169	1 Reference(s)
T23YZF	Peptidyl-glycine alpha-amidating monooxygenase	PAM	P19021	1 Reference(s)
T77FOL	Neuromodulin	GAP43	P17677	1 Reference(s)
T93VFT	Endothelin-1	EDN1	P05305	1 Reference(s)
T36SOV	Plasminogen activator inhibitor 1	SERPINE1	P05121	1 Reference(s)
T02DEN	Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide	GCG	P01275	1 Reference(s)
T48UT8	Cholesteryl ester transfer protein	CETP	P11597	1 Reference(s)
T32HPO	Aspartyl aminopeptidase	DNPEP	Q9ULA0	1 Reference(s)
T20H9F	Stromelysin-1	MMP3	P08254	1 Reference(s)
T02YLA	Alpha-lactalbumin	LALBA	P00709	1 Reference(s)
T76TED	Pro-opiomelanocortin	POMC	P01189	1 Reference(s)
T37JN5	Neutrophil gelatinase-associated lipocalin	LCN2	P80188	1 Reference(s)
T17UP9	C-C motif chemokine 2	CCL2	P13500	1 Reference(s)
T69NG6	Interleukin-10	IL10	P22301	1 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	1 Reference(s)
T51EKP	Apolipoprotein M	APOM	O95445	1 Reference(s)
T07VV7	Guanylin	GUCA2A	Q02747	1 Reference(s)
T67ZT3	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	PTEN	P60484	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	5 Reference(s)
T80WPU	Protein ABHD15	ABHD15	Q6UXT9	1 Reference(s)
T56OUM	14-3-3 protein zeta/delta	YWHAZ	P63104	1 Reference(s)
T24YWQ	Insulin-degrading enzyme	IDE	P14735	1 Reference(s)
T34HYH	Interleukin-1 alpha	IL1A	P01583	1 Reference(s)
T04V7K	Ectonucleotide pyrophosphatase/phosphodiesterase family member 7	ENPP7	Q6UWV6	1 Reference(s)
T51U9M	Carnitine O-palmitoyltransferase 1, muscle isoform	CPT1B	Q92523	1 Reference(s)
T07TMB	Cyclin-dependent kinase 1	CDK1	P06493	1 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	1 Reference(s)
T42D4V	Histone deacetylase 1	HDAC1	Q13547	1 Reference(s)
T67RBZ	Mitochondrial uncoupling protein 2	UCP2	P55851	1 Reference(s)
T67HYX	Mitochondrial uncoupling protein 3	UCP3	P55916	1 Reference(s)
T19EKF	Cholecystokinin	CCK	P06307	1 Reference(s)
T19XSL	Fatty acid-binding protein, liver	FABP1	P07148	1 Reference(s)
T23APZ	Retinol-binding protein 2	RBP2	P50120	1 Reference(s)
T38K2W	Receptor tyrosine-protein kinase erbB-2	ERBB2	P04626	1 Reference(s)
T03NWF	Sterol O-acyltransferase 1	SOAT1	P35610	1 Reference(s)
T48YPL	Aquaporin-3	AQP3	Q92482	1 Reference(s)
T53SLQ	Aquaporin-9	AQP9	O43315	1 Reference(s)
T75EH8	Glucagon-like peptide 1 receptor	GLP1R	P43220	1 Reference(s)
T52VL6	Signal transducer and activator of transcription 5A	STAT5A	P42229	1 Reference(s)
T19K8W	Signal transducer and activator of transcription 5B	STAT5B	P51692	1 Reference(s)
T18DUA	Tight junction protein ZO-1	TJP1	Q07157	1 Reference(s)
T10HL8	Intercellular adhesion molecule 1	ICAM1	P05362	1 Reference(s)
T98DNG	Natriuretic peptides A	NPPA	P01160	1 Reference(s)
T78ILO	Stearoyl-CoA desaturase	SCD	O00767	1 Reference(s)
T63GUB	Proto-oncogene c-Fos	FOS	P01100	2 Reference(s)
T68IZC	Natriuretic peptides B	NPPB	P16860	1 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	2 Reference(s)
T26KIE	Transcription factor AP-1	JUN	P05412	1 Reference(s)
T02H9U	Nuclear factor of activated T-cells, cytoplasmic 4	NFATC4	Q14934	1 Reference(s)
T49PL1	Low-density lipoprotein receptor	LDLR	P01130	1 Reference(s)
T57RCH	Glutamate decarboxylase 2	GAD2	Q05329	1 Reference(s)
T40JZG	GPI-anchor transamidase	PIGK	Q92643	1 Reference(s)
T29MD1	Mitogen-activated protein kinase 8	MAPK8	P45983	2 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	3 Reference(s)
T58CAO	Alpha-synuclein	SNCA	P37840	1 Reference(s)
T38J3Y	Gamma-enolase	ENO2	P09104	1 Reference(s)
T57FUN	Beclin-1	BECN1	Q14457	1 Reference(s)
T95EK6	Microtubule-associated proteins 1A/1B light chain 3B	MAP1LC3B	Q9GZQ8	1 Reference(s)
T67HXL	Glial cell line-derived neurotrophic factor	GDNF	P39905	1 Reference(s)
T91IWA	Ciliary neurotrophic factor	CNTF	P26441	1 Reference(s)
T18CPB	Choline O-acetyltransferase	CHAT	P28329	1 Reference(s)

Herb ID: H0769	Chinese Character: 远志
English Name: Thinleaf milkwort	Latin Name: Polygala tenuifolia
Chinese Pin Yin : Yuan Zhi	TCM-ID: TCMH2554
Therapeutic Function in Chinese : 安神	Therapeutic Function in English: Spirit calming
Herb Function: Calm the heart and soothe the mind, resolve phlegm and clear the orifices (sense organs)

Herb Description

Related Targets (Total: 86)

Related Compounds (Total: 10)