Target Description
| Type | Detail |
|---|---|
| Target ID | T18CPB |
| Protein Name | Choline O-acetyltransferase |
| Uniprot ID |
P28329 |
| Protein Name Alias | CHOACTase; ChAT; Choline acetylase; EC 2.3.1.6 |
| Gene ID |
1103 |
| Gene Symbol | CHAT |
| Gene Alias | NA |
| TTD | NA |
| Pfam | PF00755 |
| GO |
0008292:acetylcholine biosynthetic process
0043005:neuron projection 0005829:cytosol 0007274:neuromuscular synaptic transmission 0006836:neurotransmitter transport 0098793:presynapse 0005737:cytoplasm 0004102:choline O-acetyltransferase activity 0006656:phosphatidylcholine biosynthetic process 0005634:nucleus |
| PDB | 2FY3 ; 2FY5 ; 2FY4 ; 2FY2 ; 7AMD |
| Drugbank | DB00122 ; DB14006 ; DB00184 |
| KEGG | hsa:1103 |
Related Compounds (Total: 4)
C0094
Name: Gamma-Aminobutyric Acid
C0407
Name: Sinapinate
C0639
Name: (+/-)Nicotine
C0806
Name: gamma-aminobutyric acid
Related Herbs (Total: 100)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0802 | Zhi Geng | 枳梗 | NA | Citrus aurantium |
| H0626 | Xi Nan Huang Qin | 西南黄芩 | Yunnan skullcap | Scutellaria amoena |
| H0338 | Qing Ban Xia | 清半夏 | Ternate pinellia | Pinellia ternata |
| H1226 | Huai Shan Yao | 淮山药 | rhizome of biglcaf yam | Rhizoma dioscoreae |
| H0804 | Zhi Ke | 枳壳 | Seville ora nge unripe fruit | Citrus aurantium |
| H0813 | Zhi Shi | 枳实 | Seville orange young fruit | Citrus aurantium |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0292 | Niu Jiao Jian Fen | 牛角尖粉 | Buffalo horn | Bubalus bubalis |
| H0115 | Kuan Dong Hua | 款冬花 | Common coltsfoot | Tussilago farfara |
| H0549 | Tian Zhu Huang | 天竺黄 | Chinese schinzostachyum tabasheer | Concretio silicea bambusae |
| H0659 | Chai Hu Jin Gao | 柴胡浸膏 | Chinese thorowax | Bupleurum chinense |
| H1078 | Gan Chan | 干蟾 | NA | Bufo melanostictus |
| H1107 | Gua Lou Ren Shuang | 瓜蒌仁霜 | NA | Trichosanthes kirilowii |
| H0441 | Sheng Di Huang | 生地黄 | Fresh rehmannia root | Radix rehmanniae |
| H0958 | Dang Shen | 党参 | Pilose asiabell | Codonopsis pilosula |
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H0558 | Ting Li Zi | 葶苈子 | Descurainia sophia | Lepidium apetalum |
| H0275 | Mu Zei | 木贼 | Common scouring rush | Equisetum hiemale |
| H0293 | Niu Jiao Tan | 牛角炭 | Buffalo horn | Bubalus bubalis |
| H0391 | Sang Pi | 桑皮 | Prepared root-bark white mulberry | Morus alba |
| H1009 | Du Huo | 独活 | Doubleteeth pubescent angelica | Angelica pubescens |
| H0258 | Mo Han Lian | 墨旱莲 | Yerbadetajo | Eclipta prostrata |
| H0925 | Da Fu Zi | 大腹子 | Areca palm | Areca catechu |
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0972 | Di Huang | 地黄 | Rehmanniae | Rehmannia glutinosa |
| H0396 | Sang Ye | 桑叶 | White mulberry leaf | Morus alba |
| H0442 | Sheng Di Huang Zhi | 生地黄汁 | Fresh rehmannia root | Radix rehmanniae |
| H0868 | Chuan Du Huo | 川独活 | Doubleteeth pubescent angelica | Angelica pubescens |
| H0620 | Xi Gua | 西瓜 | Watermelon | Citrullus vulgaris |
| H1105 | Gua Lou Pi | 瓜蒌皮 | NA | Trichosanthes kirilowii |
| H0488 | Shui Niu Jiao Gan Jin Gao | 水牛角干浸膏 | Buffalo horn | Bubalus bubalis |
| H0769 | Yuan Zhi | 远志 | Thinleaf milkwort | Polygala tenuifolia |
| H0075 | Jing Mi | 粳米 | Rice | Oryza sativa |
| H0226 | Man Yue Mei | 蔓越莓 | Cranberry | Vaccinium oxycoccos |
| H0265 | Mu Da Qing Ye | 木大青叶 | Indigo-coloured woad leaf equivalent | Isatis indigotica |
| H0450 | Shi Chang Pu | 石菖蒲 | Grassleaved sweetflag | Acorus tatarinowii |
| H0331 | Qiang Huo | 羌活 | Incised notopterygium | Notopterygium incisum |
| H0243 | Mi Kuan Dong Hua | 蜜款冬花 | Common coltsfoot | Tussilago farfara |
| H0131 | Ban Lan | 板蓝 | Indigowoad root | Isatis indigotica |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H1221 | Hua Xiang Shu Guo Xu | 化香树果序 | NA | Platycarya strobilacea |
| H1176 | Hei Hu Jiao | 黑胡椒 | Black pepper | Piper nigrum |
| H0173 | Lu Hui | 芦荟 | Kulaso aloe dried juice | Aloe vera |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H0665 | Chai Hu Shao | 柴胡梢 | Chinese thorowax | Bupleurum chinense |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H1077 | Bai Hu Jiao | 白胡椒 | white pepper | Piper nigrum |
| H0094 | Gou Qi | 枸杞 | Chinese wolfberry fruit | Lycium chinense |
| H0137 | Ban Lan Gen | 板蓝根 | Indigowoad root | Isatis indigotica |
| H0805 | Zhi Ke Gan Jin Gao | 枳壳干浸膏 | Seville ora nge unripe fruit | Citrus aurantium |
| H0765 | Chi Dou | 赤豆 | Assuki bean | Vigna angularis |
| H0771 | Yuan Zhi Liu Jin Gao | 远志流浸膏 | Thinleaf milkwort | Polygala tenuifolia |
| H0677 | Chan Chu | 蟾蜍 | Toad | Bufo melanostictus |
| H0579 | Tu Sheng Di | 土生地 | Fresh rehmannia root | Radix rehmanniae |
| H1079 | Gan Di Huang | 干地黄 | Adhesive rehmannia dried root | Rehmannia glutinosa |
| H0093 | Ju Pi | 橘皮 | Tangerine pericarp | Citrus reticulata |
| H1204 | Hu Jiao | 胡椒 | Black pepper | Piper nigrum |
| H1088 | Gan Zhe | 甘蔗 | Sweetcane culm | Saccharum sinensis |
| H1106 | Gua Lou Ren | 瓜蒌仁 | NA | Trichosanthes kirilowii |
| H0439 | Sheng Ban Xia | 生半夏 | Ternate pinellia | Pinellia ternata |
| H0095 | Gou Qi Zi | 枸杞子 | Chinese wolfberry fruit | Lycium chinense |
| H0960 | Dang Shen Qing Gao | 党参清膏 | Root of hairy asiabell | Codonopsis pilosula |
| H1156 | Ai Di Huang | 矮地黄 | Rehmanniae | Rehmannia glutinosa |
| H0489 | Shui Niu Jiao Nong Suo Fen | 水牛角浓缩粉 | Buffalo horn | Bubalus bubalis |
| H0487 | Shui Niu Jiao | 水牛角 | Buffalo horn | Bubalus bubalis |
| H0714 | Yan Tai Chai Hu | 烟台柴胡 | Chinese thorowax | Bupleurum chinense |
| H0758 | Cheng Pi | 橙皮 | Bitter orange | Citrus aurantium |
| H0973 | Di Huang Tan | 地黄炭 | Rehmanniae | Rehmannia glutinosa |
| H0159 | Ban Xia Qu | 半夏曲 | Pinellia tuber leaven | Pinellia ternata |
| H0937 | Da Qing Ye | 大青叶 | Indigo-coloured woad leaf | Isatis indigotica |
| H0088 | Ju He | 橘核 | Tangerine seed | Citrus reticulata |
| H0408 | Bing Lang | 槟榔 | Betenutpalm | Areca catechu |
| H0938 | Da Suan | 大蒜 | Garlic | Allium sativum |
| H0263 | Mu Ban Lan Gen | 木板蓝根 | Indigowoad root | Isatis indigotica |
| H0447 | Sheng Ma | 升麻 | Bugbane | Cimicifuga foetida |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H0397 | Sang Zhi | 桑枝 | White mulberry branch | Morus alba |
| H0881 | Chuan Qiang Huo | 川羌活 | Incised notopterygium | Notopterygium incisum |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0770 | Yuan Zhi Jin Gao | 远志浸膏 | Thinleaf milkwort | Polygala tenuifolia |
| H0650 | Chai Hu | 柴胡 | Chinese thorowax | Bupleurum chinense |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0155 | Ban Xia | 半夏 | Ternate pinellia | Pinellia ternata |
| H1112 | Gua Lou Ren(1) | 栝楼仁 | NA | Trichosanthes kirilowii |
| H0451 | Shi Chang Pu Jin Gao | 石菖蒲浸膏 | Grassleaved sweetflag | Acorus tatarinowii |
| H1104 | Gua Lou | 瓜蒌 | NA | Trichosanthes kirilowii |
| H0249 | Bei Ting Li Zi | 北葶苈子 | Descurainia sophia | Lepidium apetalum |
| H0452 | Shi Chang Pu Qing Gao | 石菖蒲清膏 | Grassleaved sweetflag | Acorus tatarinowii |
| H1111 | Gua Lou Gen | 栝楼根 | NA | Trichosanthes kirilowii |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H1220 | Hua Xiang Shu Guo | 化香树果 | NA | Platycarya strobilacea |
| H1108 | Gua Lou Shi | 栝蒌实 | NA | Trichosanthes kirilowii |
| H0557 | Ting Li Cao | 葶苈草 | Descurainia sophia | Lepidium apetalum |
| H0291 | Niu Jiao Fen | 牛角粉 | Buffalo horn | Bubalus bubalis |
| H0473 | Shu Di Huang | 熟地黄 | Adhesive rehmannia cocked root | Rehmannia glutinosa |
| H0539 | Tian Hua Fen | 天花粉 | Mongolian snakegourd root | Trichosanthes kirilowii |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |
| H1024 | Fa Ban Xia | 法半夏 | Prepared pinellia tuber | Rhizoma pinelliae preparata |