Herb Description
| Herb ID: H0450 | Chinese Character: 石菖蒲 |
| English Name: Grassleaved sweetflag | Latin Name: Acorus tatarinowii |
| Chinese Pin Yin : Shi Chang Pu | TCM-ID: TCMH1920 |
| Therapeutic Function in Chinese : 开窍 | Therapeutic Function in English: Mind opening |
| Herb Function: Eliminate damp and phlegm, improve appetite, and restore consciousness and benefit the mentality | |
Related Targets (Total: 149)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
2 Reference(s) |
| T25M2J | Anoctamin-1 | ANO1 |
Q5XXA6 |
1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
3 Reference(s) |
| T22NX4 | Toll-like receptor 2 | TLR2 |
O60603 |
1 Reference(s) |
| T76QBQ | CREB-regulated transcription coactivator 2 | CRTC2 |
Q53ET0 |
1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
2 Reference(s) |
| T09INZ | Transient receptor potential cation channel subfamily A member 1 | TRPA1 |
O75762 |
3 Reference(s) |
| T60XJI | Transient receptor potential cation channel subfamily M member 8 | TRPM8 |
Q7Z2W7 |
3 Reference(s) |
| T67KTV | Transient receptor potential cation channel subfamily V member 1 | TRPV1 |
Q8NER1 |
2 Reference(s) |
| T26EZU | Myc proto-oncogene protein | MYC |
P01106 |
2 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
4 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
2 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
3 Reference(s) |
| T05PKX | Steroid 17-alpha-hydroxylase/17,20 lyase | CYP17A1 |
P05093 |
1 Reference(s) |
| T85S9Z | Cholesterol side-chain cleavage enzyme, mitochondrial | CYP11A1 |
P05108 |
1 Reference(s) |
| T76PKX | Mast/stem cell growth factor receptor Kit | KIT |
P10721 |
1 Reference(s) |
| T40DIM | Corticosteroid 11-beta-dehydrogenase isozyme 1 | HSD11B1 |
P28845 |
1 Reference(s) |
| T54VET | Protein tyrosine phosphatase type IVA 3 | PTP4A3 |
O75365 |
1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
4 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
2 Reference(s) |
| T37ADS | Early growth response protein 1 | EGR1 |
P18146 |
1 Reference(s) |
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
2 Reference(s) |
| T20JZ2 | Androgen receptor | AR |
P10275 |
2 Reference(s) |
| T12RJE | Casein kinase II subunit alpha' | CSNK2A2 |
P19784 |
1 Reference(s) |
| T47C6A | Phosphoglycerate mutase 1 | PGAM1 |
P18669 |
1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
2 Reference(s) |
| T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
1 Reference(s) |
| T30VNV | Myeloperoxidase | MPO |
P05164 |
2 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
2 Reference(s) |
| T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
2 Reference(s) |
| T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
2 Reference(s) |
| T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
1 Reference(s) |
| T97UTI | 6-phosphogluconate dehydrogenase, decarboxylating | PGD |
P52209 |
2 Reference(s) |
| T70KPE | Transient receptor potential cation channel subfamily V member 3 | TRPV3 |
Q8NET8 |
3 Reference(s) |
| T37G49 | Platelet-activating factor acetylhydrolase | PLA2G7 |
Q13093 |
1 Reference(s) |
| T34DZ7 | Interleukin-2 | IL2 |
P60568 |
1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
6 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
5 Reference(s) |
| T38N69 | Lymphokine-activated killer T-cell-originated protein kinase | PBK |
Q96KB5 |
1 Reference(s) |
| T09BRP | NA | PKB_RS07820 |
NA |
1 Reference(s) |
| T83P5X | Inhibitor of nuclear factor kappa-B kinase subunit beta | IKBKB |
O14920 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
3 Reference(s) |
| T74LFK | Neurogenic locus notch homolog protein 1 | NOTCH1 |
P46531 |
1 Reference(s) |
| T92FAW | Dual specificity protein phosphatase 1 | DUSP1 |
P28562 |
1 Reference(s) |
| T95LIF | Cannabinoid receptor 2 | CNR2 |
P34972 |
1 Reference(s) |
| T06Q1R | Amine oxidase [flavin-containing] B | MAOB |
P27338 |
3 Reference(s) |
| T69XVX | Cytochrome P450 1B1 | CYP1B1 |
Q16678 |
1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
2 Reference(s) |
| T18LX5 | Neutrophil elastase | ELANE |
P08246 |
1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
3 Reference(s) |
| T64V6C | Glutamate decarboxylase 1 | GAD1 |
Q99259 |
1 Reference(s) |
| T83RKS | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | MGAT1 |
P26572 |
2 Reference(s) |
| T73PZA | Vesicular inhibitory amino acid transporter | SLC32A1 |
Q9H598 |
1 Reference(s) |
| T68XXK | 4-aminobutyrate aminotransferase, mitochondrial | ABAT |
P80404 |
4 Reference(s) |
| T35WLZ | Sodium- and chloride-dependent GABA transporter 3 | SLC6A11 |
P48066 |
2 Reference(s) |
| T41Z1X | Gamma-aminobutyric acid receptor-associated protein | GABARAP |
O95166 |
1 Reference(s) |
| T12WTT | Interleukin-5 | IL5 |
P05113 |
1 Reference(s) |
| T84W8G | Aryl hydrocarbon receptor | AHR |
P35869 |
2 Reference(s) |
| T41INV | Nuclear receptor subfamily 1 group I member 3 | NR1I3 |
Q14994 |
1 Reference(s) |
| T58FWN | Tyrosine-protein kinase BTK | BTK |
Q06187 |
1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
8 Reference(s) |
| T01QLH | Estrogen receptor | ESR1 |
P03372 |
5 Reference(s) |
| T80OJF | Interstitial collagenase | MMP1 |
P03956 |
1 Reference(s) |
| T27U96 | Granulocyte-macrophage colony-stimulating factor | CSF2 |
P04141 |
1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
1 Reference(s) |
| T84WE9 | Vascular endothelial growth factor receptor 1 | FLT1 |
P17948 |
1 Reference(s) |
| T04MBA | Vascular endothelial growth factor receptor 2 | KDR |
P35968 |
1 Reference(s) |
| T29JZ3 | Vascular endothelial growth factor receptor 3 | FLT4 |
P35916 |
1 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
3 Reference(s) |
| T47H3O | Heat shock protein HSP 90-alpha | HSP90AA1 |
P07900 |
1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
1 Reference(s) |
| T49FZB | Linker for activation of T-cells family member 1 | LAT |
O43561 |
1 Reference(s) |
| T09ICL | Transient receptor potential cation channel subfamily V member 6 | TRPV6 |
Q9H1D0 |
1 Reference(s) |
| T83TMF | Cytochrome P450 2B1 | Cyp2b1 |
P00176 |
1 Reference(s) |
| T79VME | Cytochrome P450 4B1 | CYP4B1 |
P13584 |
1 Reference(s) |
| T70HTD | Cytochrome P450 2E1 | CYP2E1 |
P05181 |
2 Reference(s) |
| T76TED | Pro-opiomelanocortin | POMC |
P01189 |
1 Reference(s) |
| T37JN5 | Neutrophil gelatinase-associated lipocalin | LCN2 |
P80188 |
1 Reference(s) |
| T17UP9 | C-C motif chemokine 2 | CCL2 |
P13500 |
1 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
2 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
3 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
2 Reference(s) |
| T13KGH | Tyrosinase | TYR |
P14679 |
1 Reference(s) |
| T75PC7 | NA | MIR21 |
NA |
1 Reference(s) |
| T66G0O | NA | MIR30A |
NA |
1 Reference(s) |
| T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
2 Reference(s) |
| T39M6J | ATP-binding cassette sub-family C member 2 | ABCC2 |
Q92887 |
1 Reference(s) |
| T42D4V | Histone deacetylase 1 | HDAC1 |
Q13547 |
1 Reference(s) |
| T18DUA | Tight junction protein ZO-1 | TJP1 |
Q07157 |
1 Reference(s) |
| T43NBB | Solute carrier family 2, facilitated glucose transporter member 2 | SLC2A2 |
P11168 |
2 Reference(s) |
| T51WGR | Pancreas/duodenum homeobox protein 1 | PDX1 |
P52945 |
1 Reference(s) |
| T82S6C | Hexokinase-4 | GCK |
P35557 |
1 Reference(s) |
| T18CPB | Choline O-acetyltransferase | CHAT |
P28329 |
1 Reference(s) |
| T69NG6 | Interleukin-10 | IL10 |
P22301 |
1 Reference(s) |
| T51EKP | Apolipoprotein M | APOM |
O95445 |
1 Reference(s) |
| T07VV7 | Guanylin | GUCA2A |
Q02747 |
1 Reference(s) |
| T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
2 Reference(s) |
| T80WPU | Protein ABHD15 | ABHD15 |
Q6UXT9 |
1 Reference(s) |
| T56OUM | 14-3-3 protein zeta/delta | YWHAZ |
P63104 |
1 Reference(s) |
| T24YWQ | Insulin-degrading enzyme | IDE |
P14735 |
1 Reference(s) |
| T34HYH | Interleukin-1 alpha | IL1A |
P01583 |
1 Reference(s) |
| T89L4V | Insulin | INS |
P01308 |
1 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
2 Reference(s) |
| T42HHN | Follicle-stimulating hormone receptor | FSHR |
P23945 |
1 Reference(s) |
| T90ADC | BH3-interacting domain death agonist | BID |
P55957 |
1 Reference(s) |
| T05O6O | Estrogen receptor beta | ESR2 |
Q92731 |
1 Reference(s) |
| T09KPZ | Vimentin | VIM |
P08670 |
1 Reference(s) |
| T52CKD | Pro-epidermal growth factor | EGF |
P01133 |
1 Reference(s) |
| T42PUG | Solute carrier family 2, facilitated glucose transporter member 1 | SLC2A1 |
P11166 |
1 Reference(s) |
| T68SE0 | Solute carrier family 2, facilitated glucose transporter member 4 | SLC2A4 |
P14672 |
1 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
1 Reference(s) |
| T95K0K | Interferon alpha-1/13 | IFNA1; IFNA13 |
P01562 |
1 Reference(s) |
| T64LKA | Bile salt export pump | ABCB11 |
O95342 |
2 Reference(s) |
| T93SFQ | NAD-dependent protein deacetylase sirtuin-1 | SIRT1 |
Q96EB6 |
1 Reference(s) |
| T78O6C | Mothers against decapentaplegic homolog 3 | SMAD3 |
P84022 |
1 Reference(s) |
| T84CEG | Claudin-5 | CLDN5 |
O00501 |
1 Reference(s) |
| T30AEN | Aquaporin-5 | AQP5 |
P55064 |
1 Reference(s) |
| T02GD4 | Tumor necrosis factor ligand superfamily member 6 | FASLG |
P48023 |
1 Reference(s) |
| T47RAK | NA | MIR145 |
NA |
1 Reference(s) |
| T11BI7 | Toll-like receptor 4 | TLR4 |
O00206 |
1 Reference(s) |
| T75NEV | Aquaporin-1 | AQP1 |
P29972 |
1 Reference(s) |
| T54SZZ | Endoplasmic reticulum chaperone BiP | HSPA5 |
P11021 |
1 Reference(s) |
| T37SV3 | Occludin | OCLN |
Q16625 |
1 Reference(s) |
| T69F5W | Forkhead box protein D3 | FOXD3 |
Q9UJU5 |
1 Reference(s) |
| T13I7C | Transforming growth factor beta-2 proprotein | TGFB2 |
P61812 |
1 Reference(s) |
| T44EUX | Fragile X mental retardation syndrome-related protein 1 | FXR1 |
P51114 |
1 Reference(s) |
| T92LK2 | Tumor necrosis factor ligand superfamily member 10 | TNFSF10 |
P50591 |
1 Reference(s) |
| T26CFB | DNA damage-inducible transcript 3 protein | DDIT3 |
P35638;P0DPQ6 |
1 Reference(s) |
| T53YWQ | Pro-neuropeptide Y [Cleaved into: Neuropeptide Y | NPY |
P01303 |
1 Reference(s) |
| T70SFS | Superoxide dismutase [Mn], mitochondrial | SOD2 |
P04179 |
1 Reference(s) |
| T54B00 | P2X purinoceptor 7 | P2RX7 |
Q99572 |
1 Reference(s) |
| T98DNG | Natriuretic peptides A | NPPA |
P01160 |
1 Reference(s) |
| T78ILO | Stearoyl-CoA desaturase | SCD |
O00767 |
1 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
2 Reference(s) |
| T68IZC | Natriuretic peptides B | NPPB |
P16860 |
1 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
1 Reference(s) |
| T02H9U | Nuclear factor of activated T-cells, cytoplasmic 4 | NFATC4 |
Q14934 |
1 Reference(s) |
| T21UJU | Troponin I, cardiac muscle | TNNI3 |
P19429 |
1 Reference(s) |
| T57RCH | Glutamate decarboxylase 2 | GAD2 |
Q05329 |
1 Reference(s) |
| T40JZG | GPI-anchor transamidase | PIGK |
Q92643 |
1 Reference(s) |
| T29MD1 | Mitogen-activated protein kinase 8 | MAPK8 |
P45983 |
2 Reference(s) |
| T58CAO | Alpha-synuclein | SNCA |
P37840 |
1 Reference(s) |
| T38J3Y | Gamma-enolase | ENO2 |
P09104 |
1 Reference(s) |
| T57FUN | Beclin-1 | BECN1 |
Q14457 |
1 Reference(s) |
| T95EK6 | Microtubule-associated proteins 1A/1B light chain 3B | MAP1LC3B |
Q9GZQ8 |
1 Reference(s) |
| T67HXL | Glial cell line-derived neurotrophic factor | GDNF |
P39905 |
1 Reference(s) |
| T91IWA | Ciliary neurotrophic factor | CNTF |
P26441 |
1 Reference(s) |
| T82S9G | DNA repair protein RAD51 homolog 1 | RAD51 |
Q06609 |
1 Reference(s) |
Related Compounds (Total: 26)
C0064
Name: Eugenol
C0447
Name: Thymol
C0219
Name: Methyleugenol
C0453
Name: Trans-Asarone
C0094
Name: Gamma-Aminobutyric Acid
key description of the interaction between compound and target