HIT-result

Type	Detail
Target ID	T64LKA
Protein Name	Bile salt export pump
Uniprot ID	O95342
Protein Name Alias	EC 7.6.2.-; ATP-binding cassette sub-family B member 11
Gene ID	8647
Gene Symbol	ABCB11
Gene Alias	BSEP
TTD	T33969: Research target
Pfam	PF00005 ; PF00664
GO	0016567:protein ubiquitination 0006631:fatty acid metabolic process 1904251:regulation of bile acid metabolic process 0070062:extracellular exosome 0055088:lipid homeostasis 0016887:ATPase activity 0016324:apical plasma membrane 0017144:drug metabolic process 0009986:cell surface 0046691:intracellular canaliculus 0015125:bile acid transmembrane transporter activity 0046581:intercellular canaliculus 0042626:ATPase-coupled transmembrane transporter activity 0006699:bile acid biosynthetic process 0055037:recycling endosome 0005524:ATP binding 0005886:plasma membrane 0016021:integral component of membrane 0008559:ABC-type xenobiotic transporter activity 0055085:transmembrane transport 0042632:cholesterol homeostasis 0015126:canalicular bile acid transmembrane transporter activity 0055038:recycling endosome membrane 0046618:drug export 0006855:drug transmembrane transport 0015432:ABC-type bile acid transporter activity 0120189:positive regulation of bile acid secretion 0055091:phospholipid homeostasis 0008206:bile acid metabolic process 0015721:bile acid and bile salt transport 0015722:canalicular bile acid transport 0031998:regulation of fatty acid beta-oxidation 0005768:endosome
PDB	6LR0
Drugbank	DB01072 ; DB00586 ; DB00091 ; DB01211 ; DB04348 ; DB00328 ; DB05804 ; DB00911 ; DB00206 ; DB00421 ; DB01015 ; DB00977 ; DB00227 ; DB00255 ; DB00822 ; DB03619 ; DB01118 ; DB00675 ; DB14057 ; DB00501 ; DB02659 ; DB00503 ; DB00619 ; DB01174 ; DB00833 ; DB13345 ; DB00637 ; DB00176 ; DB00997 ; DB00572 ; DB00335 ; DB01026 ; DB00412 ; DB01222 ; DB00270 ; DB01039 ; DB00694 ; DB01165 ; DB00342 ; DB01234 ; DB00390 ; DB00224 ; DB00698 ; DB00243 ; DB12319 ; DB00477 ; DB00622 ; DB00439 ; DB01045 ; DB09078 ; DB00975 ; DB01232 ; DB02703 ; DB01023 ; DB00559 ; DB00301 ; DB00570 ; DB00455 ; DB01138 ; DB00396 ; DB01229 ; DB01098 ; DB00693 ; DB15822 ; DB00197 ; DB00541 ; DB00199 ; DB00220 ; DB00932 ; DB06290 ; DB14649 ; DB13751 ; DB12070 ; DB09374 ; DB00678 ; DB12712 ; DB00912 ; DB00641 ; DB00222 ; DB00834 ; DB00908 ; DB00257 ; DB15719 ; DB01586 ; DB00625 ; DB00966 ; DB00482 ; DB08860 ; DB00973 ; DB14761 ; DB01016 ; DB01067 ; DB00175 ; DB01054 ; DB01115 ; DB01601 ; DB02123 ; DB01076 ; DB05990 ; DB00275 ; DB00171 ; DB00788 ; DB01149
KEGG	hsa:8647

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1075	Gan Cao Liu Jin Gao	甘草流浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0102	Jue Ming Zi	决明子	Sickle senna seed	Cassia tora
H1163	He Bao Cao	荷包草	NA	Lamprocapnos spectabilis
H0472	Shu Da Huang	熟大黄	NA	Rheum palmatum
H0250	Mi Zi Wan	蜜紫菀	Tatarian aster	Aster tataricus
H0110	Ku Mu	苦木	Indian quassiawood	Picrasma quassioides
H1073	Gan Cao Jie	甘草节	Glycyrrhiza uralensis fisch	Glycyrrhiza uralensis
H0452	Shi Chang Pu Qing Gao	石菖蒲清膏	Grassleaved sweetflag	Acorus tatarinowii
H0571	Tu Gan Cao	土甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H1067	Gan Cao Fen	甘草粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0451	Shi Chang Pu Jin Gao	石菖蒲浸膏	Grassleaved sweetflag	Acorus tatarinowii
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H1213	Hu Zhang	虎杖	Japanese fleeceflower	Polygonum cuspidatum
H1070	Gan Cao Gan Gao Fen	甘草干膏粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H1026	Fan Hun Cao	返魂草	Tatarian aster	Aster tataricus
H1173	Hei Chou	黑丑	Pharbitis seed	Semen pharbitidis
H0298	Niu Xi Xi	牛西西	Patience dock	Rumex patientia
H1069	Gan Cao Gan Gao	甘草干膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0056	Jin Qiao Mai	金荞麦	Wild buckwheat rhizome	Rhizoma fagopyri cymosi
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0809	Zhi Mu	知母	Common anemarrhena	Anemarrhena asphodeloides
H0240	Mi Gan Cao	蜜甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1074	Gan Cao Jin Gao	甘草浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1235	Huang Hao	黄蒿	Virg ate wormwood	Artemisia scoparia
H0689	Xue Feng Teng	血风藤	NA	Ventilago leiocarpa
H0444	Sheng Gan Cao	生甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1166	He Shou Wu	何首乌	Tuber fleeceflower	Polygonum multiflorum
H0450	Shi Chang Pu	石菖蒲	Grassleaved sweetflag	Acorus tatarinowii
H1100	Gu Jing Cao	谷精草	Pipewart	Eriocaulon buergerianum
H0853	Zi Wan	紫菀	Tatarion aster	Aster tataricus
H0540	Tian Ji Huang	田基黄	all - grass of japanese st. johnswort	Grangea maderaspatana
H1066	Gan Cao	甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1000	Dong Gua Zi	冬瓜子	Chinese waxgourd seed	Benincasa hispida
H1071	Gan Cao Gan Jin Gao	甘草干浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1184	Bai Lian	白蔹	Japanese ampelopsis	Ampelopsis japonica
H0006	Bai Qu Cai	白屈菜	Greater celandine	Chelidonium majus
H1011	Bai Chou	白丑	Pharbitis seed	Semen pharbitidis
H1072	Gan Cao Gao	甘草膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0998	Dong Gua Pi	冬瓜皮	Chinese waxgourd peel	Benincasa hispida
H1223	Huai Hun Cao	还魂草	NA	Aster tataricus

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 43)