Target Description

Type Detail
Target ID T95LIF
Protein Name Cannabinoid receptor 2
Uniprot ID P34972
Protein Name Alias CB-2;  CB2;  hCB2;  CX5
Gene ID 1269
Gene Symbol CNR2
Gene Alias CB2A;  CB2B
TTD T37693: Successful target
Pfam PF00001
GO
0031234:extrinsic component of cytoplasmic side of plasma membrane

0007187:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

0030425:dendrite

0032496:response to lipopolysaccharide

0007186:G protein-coupled receptor signaling pathway

0033004:negative regulation of mast cell activation

0038171:cannabinoid signaling pathway

0030595:leukocyte chemotaxis

0005886:plasma membrane

0005737:cytoplasm

0004930:G protein-coupled receptor activity

0043204:perikaryon

0005887:integral component of plasma membrane

0005783:endoplasmic reticulum

0001975:response to amphetamine

0050728:negative regulation of inflammatory response

0006955:immune response

0019233:sensory perception of pain

0051001:negative regulation of nitric-oxide synthase activity

0019222:regulation of metabolic process

0006954:inflammatory response

0004949:cannabinoid receptor activity

0032229:negative regulation of synaptic transmission, GABAergic

0045759:negative regulation of action potential

0007189:adenylate cyclase-activating G protein-coupled receptor signaling pathway

PDB 2KI9 ; 6KPF ; 6PT0 ; 6KPC ; 5ZTY
Drugbank DB00486 ; DB14011 ; DB14009 ; DB00470 ; DB11755 ; DB02955 ; DB09061 ; DB06202
KEGG hsa:1269

Related Compounds  (Total: 7)

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C0299
Name: Phenethylamine
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C0547
Name: Caryophyllene
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C0675
Name: 2-Arachidonoylglycerol
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C0752
Name: (1R,9S)-4,11,11-Trimethyl-8-Methylenebicyclo[7.2.0]Undec-4-Ene,Caryophellene,Β-Caryophyllene
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C0883
Name: Cannabidiol


Related Herbs  (Total: 100)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0609 Wu Wei Zi Liu Jin Gao五味子流浸膏 Five-flavor berrySchisandra chinensis
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0613 Wu Yue Ai五月艾 ArtemisiaArtemisia princeps
H0605 Wu Wei Zi五味子 Chinese magnoliavineSchisandra chinensis
H0246 Mi Ma Huang蜜麻黄 Ephedra equisetinEphedra sinica
H0802 Zhi Geng枳梗 NACitrus aurantium
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0198 Ma Huang Gao麻黄膏 Chinese ephedraEphedra sinica
H0002 Hui Xiang茴香 Fennel fruitFoeniculum vulgare
H0357 Ren Shen人参 GinsengPanax ginseng
H0630 Ce Bai Ye侧柏叶 Chinese arborvitae leafThuja orientalis
H0804 Zhi Ke枳壳 Seville ora nge unripe fruitCitrus aurantium
H0821 Chu Ling Dan Cao臭灵丹草 laggera pterodontaLaggera pterodonta
H0813 Zhi Shi枳实 Seville orange young fruitCitrus aurantium
H0911 Ba Jiao Hui Xiang八角茴香 Chinese star aniseIllicium verum
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H0200 Ma Huang Gen麻黄根 Chinese ephedra rootEphedra sinica
H0585 Tu Yin Chen Hao土茵陈蒿 Capillary wormwoodArtemisia capillaris
H0943 Dan Cai淡菜 MusselMytilus edulis
H0154 Ai Ye You艾叶油 Argy wormwood leafArtemisia argyi
H0430 She Chuang Zi蛇床子 Common cnidiumCnidium monnieri
H0607 Wu Wei Zi Jin Chu Wu五味子浸出物 Five-flavor berrySchisandra chinensis
H0631 Xi Yang Shen西洋参 American ginsengPanax quinquefolium
H0902 Chun Pi椿皮 Ailanthus bark, tree of heaven barkAilanthi cortex
H0746 Yin Chen Hao Gan Jin Gao茵陈蒿干浸膏 Capillary wormwoodArtemisia capillaris
H0028 Jiang Huang姜黄 Common turmericCurcuma longa
H0219 Man Shan Hong满山红 Dahurian rhododendronRhododendron dauricum
H0380 San Qi Gan Jin Gao三七干浸膏 SanchiPanax notoginseng
H0418 Shan Yin Chen山茵陈 Capillary wormwoodArtemisia capillaris
H0216 Man Jing Ye蔓荆叶 Threeleaf chastetree leafVitex trifolia
H1085 Gan Song甘松 Chinese nardostachysNardostachys chinensis
H0625 Ce Bai Tan侧柏炭 Oriental arbor-vitaePlatycladus orientalis
H0968 Di Feng Pi地枫皮 Difengpi anisetreeIllicium difengpi
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0851 Zi Su Zi紫苏子 Perilia fruitFructus perillae
H1097 Gong Ding Xiang公丁香 NASyzygium aromaticum
H0551 Cang Zhu苍术 Swordlike atractylodesAtractylodes lancea
H0201 Ma Huang Jin Gao麻黄浸膏 Chinese ephedraEphedra sinica
H0850 Zi Su Ye紫苏叶 Common perilla leafPerilla frutescens var. arguta
H0450 Shi Chang Pu石菖蒲 Grassleaved sweetflagAcorus tatarinowii
H0378 San Qi三七 SanchiPanax notoginseng
H0384 San Qi Ye三七叶 Folium panax notoginsengPanax notoginseng
H0652 Xiang Yuan Pi香橼皮 Wilson citronCitrus medica
H1231 Huang Bai Tan黄柏炭 Amur corktreePhellodendron amurense
H0365 Rou Dou Kou肉豆蔻 Common nutmegMyristica fragrans
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0933 Da Ji(1)大蓟 NAHerba cirsii japonici
H0398 Sha Ren砂仁 Villous amomumAmomum villosum
H0895 Chuan Yu Jin川郁金 TurmericCurcuma longa
H0164 Ban Zhi Lian半枝莲 Barbed skullcapScutellaria barbata
H1191 Hong Shen红参 Red ginsengRadix ginseng rubra
H0805 Zhi Ke Gan Jin Gao枳壳干浸膏 Seville ora nge unripe fruitCitrus aurantium
H0849 Zi Su Geng紫苏梗 Common perilla stemPerilla frutescens var. arguta
H0385 San Qi Ye Jing三七叶茎 SanchiPanax notoginseng
H0399 Sha Ren Ye砂仁叶 NAAmomum villosum
H1214 Hua Jiao花椒 Bunge pricklyashZanthoxylum bungeanum
H0745 Yin Chen Hao茵陈蒿 Capillary wormwoodArtemisia capillaris
H0093 Ju Pi橘皮 Tangerine pericarpCitrus reticulata
H0729 Ye Ju Hua野菊花 Indian wild chrysanthemum flowerChrysanthemum indicum
H1240 Huang Jing Zi黄荆子 NAVitex negundo
H0990 Ding Xiang丁香 Clove treeSyzygium aromaticum
H0410 Shan Jiang Zi山姜子 NALitsea cubeba
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0816 Chu Ling Dan臭灵丹 laggera pterodontaLaggera pterodonta
H0103 Ai Ye艾叶 Argy wormwood leafArtemisia argyi
H0382 San Qi Hua三七花 SanchiPanax notoginseng
H0758 Cheng Pi橙皮 Bitter orangeCitrus aurantium
H0383 San Qi Jing Ye三七茎叶 SanchiPanax notoginseng
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin
H0381 San Qi Gao Fen三七膏粉 SanchiPanax notoginseng
H0221 Bei Liu Ji Nu北刘寄奴 ‎Diverse wormwood herbHerba artemisiae anomalae
H1115 Guan Huang Bai关黄柏 Amur cork treePhellodendron amurense
H0606 Wu Wei Zi Chun Jin Gao五味子醇浸膏 Five-flavor berrySchisandra chinensis
H1005 Dou Chi Jiang豆豉姜 Folium litseae cubebaeLitsea cubeba
H0217 Man Jing Zi蔓荆子 Threeleaf chastetree fruitVitex trifolia
H0197 Ma Huang麻黄 Chinese ephedraEphedra sinica
H1230 Huang Bai Fen黄柏粉 Amur corktreePhellodendron amurense
H0088 Ju He橘核 Tangerine seedCitrus reticulata
H0342 Qing Hao青蒿 sweet wormwoodArtemisia carvifolia
H0072 Jing Jie荆芥 Fineleaf schizonepetaSchizonepeta tenuifolia
H1022 E Zhu莪术 Zedoray rhizomeCurcuma aeruginosa
H0736 Yi Dian Hong一点红 Sowthistle tasselflowerEmilia sonchifolia
H0608 Wu Wei Zi Jin Gao五味子浸膏 Five-flavor berrySchisandra chinensis
H0651 Xiang Yuan香橼 Wilson citronCitrus medica
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H0704 Yan Guan Huang Bai盐关黄柏 Amur cork treePhellodendron amurense
H0764 Yu Xing Cao鱼腥草 Heartleaf houttuyniaHouttuynia cordata
H0403 Shan Cang Zi山苍子 NALitsea cubeba
H0941 Da Zao大枣 Chinese dateZiziphus jujuba
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H1228 Huang Bai黄柏 Amur corktreePhellodendron amurense
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0946 A Wei阿魏 Asafetida giantfennel resinFerula assafoetida
H0003 Huo Ma Ren火麻仁 Hemp fimble seedCannabis sativa
H1006 Dou Kou豆蔻 Round cardamon fruitFructus amomi rotundus
H0412 Bing Pian冰片 BorneolDryobalanops aromatica
H0303 Bi Cheng Qie毕澄茄 Cubeba pepperPiper cubeba
H0416 Shan Shen山参 NAPanax ginseng
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H0204 Ma Ren麻仁 NACannabis sativa