Herb Description
| Herb ID: H0631 | Chinese Character: 西洋参 |
| English Name: American ginseng | Latin Name: Panax quinquefolium |
| Chinese Pin Yin : Xi Yang Shen | TCM-ID: TCMH2241 |
| Therapeutic Function in Chinese : 补虚 | Therapeutic Function in English: For tonifying weakness |
| Herb Function: Replenish qi and promote body fluids, nourish yin and clear heat | |
Related Targets (Total: 91)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T09INZ | Transient receptor potential cation channel subfamily A member 1 | TRPA1 |
O75762 |
1 Reference(s) |
| T58XLK | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 |
P18031 |
2 Reference(s) |
| T77PFO | Histone deacetylase 6 | HDAC6 |
Q9UBN7 |
1 Reference(s) |
| T22NX4 | Toll-like receptor 2 | TLR2 |
O60603 |
1 Reference(s) |
| T76QBQ | CREB-regulated transcription coactivator 2 | CRTC2 |
Q53ET0 |
1 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
1 Reference(s) |
| T37G49 | Platelet-activating factor acetylhydrolase | PLA2G7 |
Q13093 |
1 Reference(s) |
| T15I0F | Proteasome activator complex subunit 1 | PSME1 |
Q06323 |
1 Reference(s) |
| T44BWE | Adiponectin receptor protein 2 | ADIPOR2 |
Q86V24 |
1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
3 Reference(s) |
| T25RTY | C-C motif chemokine 22 | CCL22 |
O00626 |
1 Reference(s) |
| T77O2V | Mannose-1-phosphate guanyltransferase beta | GMPPB |
Q9Y5P6 |
1 Reference(s) |
| T47H3O | Heat shock protein HSP 90-alpha | HSP90AA1 |
P07900 |
1 Reference(s) |
| T24VHL | Olfactory receptor 51E1 | OR51E1 |
Q8TCB6 |
1 Reference(s) |
| T16MRU | NACHT, LRR and PYD domains-containing protein 3 | NLRP3 |
Q96P20 |
1 Reference(s) |
| T27F5B | Interleukin-1 receptor-associated kinase 1 | IRAK1 |
P51617 |
1 Reference(s) |
| T84W8G | Aryl hydrocarbon receptor | AHR |
P35869 |
1 Reference(s) |
| T67KTV | Transient receptor potential cation channel subfamily V member 1 | TRPV1 |
Q8NER1 |
1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
1 Reference(s) |
| T47G3X | Glucocorticoid receptor | NR3C1 |
P04150 |
1 Reference(s) |
| T95LIF | Cannabinoid receptor 2 | CNR2 |
P34972 |
1 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
1 Reference(s) |
| T34DZ7 | Interleukin-2 | IL2 |
P60568 |
2 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
1 Reference(s) |
| T76TED | Pro-opiomelanocortin | POMC |
P01189 |
1 Reference(s) |
| T37JN5 | Neutrophil gelatinase-associated lipocalin | LCN2 |
P80188 |
1 Reference(s) |
| T17UP9 | C-C motif chemokine 2 | CCL2 |
P13500 |
1 Reference(s) |
| T08U92 | Mitochondrial brown fat uncoupling protein 1 | UCP1 |
P25874 |
1 Reference(s) |
| T13WH4 | Interferon-induced, double-stranded RNA-activated protein kinase | EIF2AK2 |
P19525 |
1 Reference(s) |
| T01HJQ | Calreticulin | CALR |
P27797 |
1 Reference(s) |
| T86J48 | Sodium/glucose cotransporter 1 | SLC5A1 |
P13866 |
2 Reference(s) |
| T29TYJ | Inositol-3-phosphate synthase 1 | ISYNA1 |
Q9NPH2 |
2 Reference(s) |
| T43N2D | Epidermal growth factor receptor | EGFR |
P00533 |
1 Reference(s) |
| T04V7K | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 | ENPP7 |
Q6UWV6 |
1 Reference(s) |
| T51U9M | Carnitine O-palmitoyltransferase 1, muscle isoform | CPT1B |
Q92523 |
1 Reference(s) |
| T07TMB | Cyclin-dependent kinase 1 | CDK1 |
P06493 |
1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
1 Reference(s) |
| T69NG6 | Interleukin-10 | IL10 |
P22301 |
1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
1 Reference(s) |
| T51EKP | Apolipoprotein M | APOM |
O95445 |
1 Reference(s) |
| T07VV7 | Guanylin | GUCA2A |
Q02747 |
1 Reference(s) |
| T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
3 Reference(s) |
| T80WPU | Protein ABHD15 | ABHD15 |
Q6UXT9 |
1 Reference(s) |
| T56OUM | 14-3-3 protein zeta/delta | YWHAZ |
P63104 |
1 Reference(s) |
| T24YWQ | Insulin-degrading enzyme | IDE |
P14735 |
1 Reference(s) |
| T34HYH | Interleukin-1 alpha | IL1A |
P01583 |
1 Reference(s) |
| T19XSL | Fatty acid-binding protein, liver | FABP1 |
P07148 |
1 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
2 Reference(s) |
| T98DNG | Natriuretic peptides A | NPPA |
P01160 |
1 Reference(s) |
| T78ILO | Stearoyl-CoA desaturase | SCD |
O00767 |
1 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
1 Reference(s) |
| T68IZC | Natriuretic peptides B | NPPB |
P16860 |
1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
2 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
1 Reference(s) |
| T02H9U | Nuclear factor of activated T-cells, cytoplasmic 4 | NFATC4 |
Q14934 |
1 Reference(s) |
| T27S6H | Pulmonary surfactant-associated protein B | SFTPB |
P07988 |
1 Reference(s) |
| T72BXP | Platelet endothelial cell adhesion molecule | PECAM1 |
P16284 |
1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
1 Reference(s) |
| T04MBA | Vascular endothelial growth factor receptor 2 | KDR |
P35968 |
1 Reference(s) |
| T19BO9 | Bone morphogenetic protein 4 | BMP4 |
P12644 |
1 Reference(s) |
| T34AW3 | Lipopolysaccharide-binding protein | LBP |
P18428 |
1 Reference(s) |
| T89GCM | Inward rectifier potassium channel 2 | KCNJ2 |
P63252 |
1 Reference(s) |
| T90XYZ | C-reactive protein | CRP |
P02741 |
1 Reference(s) |
| T43Y5O | D(3) dopamine receptor | DRD3 |
P35462 |
1 Reference(s) |
| T44S1A | Apolipoprotein A-I | APOA1 |
P02647 |
1 Reference(s) |
| T74P7I | G-protein coupled bile acid receptor 1 | GPBAR1 |
Q8TDU6 |
1 Reference(s) |
| T68WYW | von Willebrand factor | VWF |
P04275 |
1 Reference(s) |
| T04WT7 | Fibronectin | FN1 |
P02751 |
3 Reference(s) |
| T82ALJ | Glycogen synthase kinase-3 beta | GSK3B |
P49841 |
1 Reference(s) |
| T20VPX | Cyclin-dependent-like kinase 5 | CDK5 |
Q00535 |
1 Reference(s) |
| T83QHM | Beta-nerve growth factor | NGF |
P01138 |
1 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
2 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
1 Reference(s) |
| T94S85 | Collagen alpha-1(I) chain | COL1A1 |
P02452 |
1 Reference(s) |
| T50V79 | Interleukin-4 | IL4 |
P05112 |
1 Reference(s) |
| T00T9M | Thrombospondin-1 | THBS1 |
P07996 |
1 Reference(s) |
| T61J7T | Mothers against decapentaplegic homolog 2 | SMAD2 |
Q15796 |
1 Reference(s) |
| T94H37 | Cadherin-1 | CDH1 |
P12830 |
1 Reference(s) |
| T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
1 Reference(s) |
| T25H22 | Protein kinase C beta type | PRKCB |
P05771 |
1 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
1 Reference(s) |
| T93LMN | Microtubule-associated protein tau | MAPT |
P10636 |
1 Reference(s) |
| T25YP8 | Aquaporin-4 | AQP4 |
P55087 |
1 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
1 Reference(s) |
| T17CNB | Thioredoxin | TXN |
P10599 |
1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
1 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
1 Reference(s) |
| T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
1 Reference(s) |
Related Compounds (Total: 16)
C0259
Name: Octanol
C0416
Name: Stearic Acid
C0285
Name: Palmitic Acid
C0258
Name: Octanoic Acid
C0148
Name: Isoeugenol
key description of the interaction between compound and target