Target Description

Type Detail
Target ID T15I0F
Protein Name Proteasome activator complex subunit 1
Uniprot ID Q06323
Protein Name Alias 11S regulator complex subunit alpha;  REG-alpha;  Activator of multicatalytic protease subunit 1;  Interferon gamma up-regulated I-5111 protein;  IGUP I-5111;  Proteasome activator 28 subunit alpha;  PA28a;  PA28alpha
Gene ID 5720
Gene Symbol PSME1
Gene Alias IFI5111
TTD NA
Pfam PF02251 ; PF02252
GO
0060071:Wnt signaling pathway, planar cell polarity pathway

0043488:regulation of mRNA stability

0002479:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

0070062:extracellular exosome

1902036:regulation of hematopoietic stem cell differentiation

0070498:interleukin-1-mediated signaling pathway

0010950:positive regulation of endopeptidase activity

1901990:regulation of mitotic cell cycle phase transition

0005829:cytosol

0036388:pre-replicative complex assembly

0006521:regulation of cellular amino acid metabolic process

0002223:stimulatory C-type lectin receptor signaling pathway

0010972:negative regulation of G2/M transition of mitotic cell cycle

0050852:T cell receptor signaling pathway

0043161:proteasome-mediated ubiquitin-dependent protein catabolic process

0061133:endopeptidase activator activity

0000165:MAPK cascade

0038095:Fc-epsilon receptor signaling pathway

2000045:regulation of G1/S transition of mitotic cell cycle

0031145:anaphase-promoting complex-dependent catabolic process

0061418:regulation of transcription from RNA polymerase II promoter in response to hypoxia

0038061:NIK/NF-kappaB signaling

0055085:transmembrane transport

0008537:proteasome activator complex

0000209:protein polyubiquitination

0031146:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

0005737:cytoplasm

0090090:negative regulation of canonical Wnt signaling pathway

0033209:tumor necrosis factor-mediated signaling pathway

0005654:nucleoplasm

0061136:regulation of proteasomal protein catabolic process

0016579:protein deubiquitination

0090263:positive regulation of canonical Wnt signaling pathway

0043687:post-translational protein modification

0000502:proteasome complex

PDB 1AVO
Drugbank DB09130
KEGG hsa:5720

Related Compounds  (Total: 1)

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C1201
Name: Butylated Hydroxytoluene


Related Herbs  (Total: 36)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0402 Sha Yuan Zi沙苑子 Flatstem milkvetch seedSemen astragali complanati
H0416 Shan Shen山参 NAPanax ginseng
H0401 Sha Yuan Ji Li沙苑蒺藜 Seed of flaststem milkvetchSemen astragali complanati
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0385 San Qi Ye Jing三七叶茎 SanchiPanax notoginseng
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H0613 Wu Yue Ai五月艾 ArtemisiaArtemisia princeps
H0561 Tong Ji Li潼蒺藜 Flatstem milkvetch seedSemen astragali complanati
H0154 Ai Ye You艾叶油 Argy wormwood leafArtemisia argyi
H0382 San Qi Hua三七花 SanchiPanax notoginseng
H0104 Bai Zhu白术 Largehead atractylodesAtractylodes macrocephala
H0524 Tan Xiang檀香 SandalwoodSantalum album
H0852 Zi Tan紫檀 Burmacoast padaukPterocarpus indicus
H0631 Xi Yang Shen西洋参 American ginsengPanax quinquefolium
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0354 Ren Dong Teng忍冬藤 Japanese honeysuckle vineLonicera japonica
H0134 Li Zhi He荔枝核 Lychee seedLitchi chinensis
H0103 Ai Ye艾叶 Argy wormwood leafArtemisia argyi
H0169 Lou Lu漏芦 Uniflower swisscentauryRhaponticum uniflorum
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin
H0383 San Qi Jing Ye三七茎叶 SanchiPanax notoginseng
H0188 Lv Cao葎草 Japanese hopHumulus japonicus
H0384 San Qi Ye三七叶 Folium panax notoginsengPanax notoginseng
H0551 Cang Zhu苍术 Swordlike atractylodesAtractylodes lancea
H0427 Shan Zhu Yu山茱萸 Asiatic cornelian cherryCornus officinalis
H0924 Da Fu Pi大腹皮 pericarp of betelnutpalmPericarpium arecae
H0085 Jiu Yu Rou酒萸肉 Asiatic cornelian cherryCornus officinalis
H0357 Ren Shen人参 GinsengPanax ginseng
H0380 San Qi Gan Jin Gao三七干浸膏 SanchiPanax notoginseng
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H0381 San Qi Gao Fen三七膏粉 SanchiPanax notoginseng