Herb Description

Herb ID:   H0169 Chinese Character:   漏芦
English Name:  Uniflower swisscentaury Latin Name:  Rhaponticum uniflorum
Chinese Pin Yin :  Lou Lu TCM-ID:  TCMH1331
Therapeutic Function in Chinese :  清热 Therapeutic Function in English:  Heat clearence
Herb Function:  Remove toxic heat for treating subcutaneous infections, promote lactation, and relieve muscular contracture

Related Targets  (Total: 91)

Target idProtein NameGene SymbolUniprot IDNo.of Literature Evidence
T58XLK Tyrosine-protein phosphatase non-receptor type 1PTPN1 P18031
1 Reference(s)
T90ZKN Cathepsin BCTSB P07858
1 Reference(s)
T70OGQ Sodium/potassium-transporting ATPase subunit alpha-1ATP1A1 P05023
1 Reference(s)
T83YZD AcetylcholinesteraseACHE P22303
1 Reference(s)
T63GUB Proto-oncogene c-FosFOS P01100
1 Reference(s)
T73EVE Cyclic AMP-dependent transcription factor ATF-2ATF2 P15336
1 Reference(s)
T75B9S Cyclic AMP-responsive element-binding protein 1CREB1 P16220
1 Reference(s)
T45G32 Proto-oncogene tyrosine-protein kinase SrcSRC P12931
1 Reference(s)
T34FQX Protein kinase C zeta typePRKCZ Q05513
1 Reference(s)
T74QOR Tyrosine-protein kinase JAK3JAK3 P52333
1 Reference(s)
T25NSJ Mitogen-activated protein kinase 3MAPK3 P27361
1 Reference(s)
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
1 Reference(s)
T04H8Y Beta-secretase 1BACE1 P56817
1 Reference(s)
T58J2Y Peroxisome proliferator-activated receptor gammaPPARG P37231
1 Reference(s)
T57L0X Oxysterols receptor LXR-alphaNR1H3 Q13133
1 Reference(s)
T68XXK 4-aminobutyrate aminotransferase, mitochondrialABAT P80404
1 Reference(s)
T01QLH Estrogen receptorESR1 P03372
1 Reference(s)
T57HGP Tumor necrosis factor receptor superfamily member 6FAS P25445
1 Reference(s)
T32KN9 Alpha-amylase 1AAMY1A P0DUB6
1 Reference(s)
T49ORJ Peroxisome proliferator-activated receptor alphaPPARA Q07869
3 Reference(s)
T12PIB Lysosomal alpha-glucosidaseGAA P10253
1 Reference(s)
T06RMZ Nuclear factor NF-kappa-B p105 subunitNFKB1 P19838
2 Reference(s)
T50SX0 Nuclear receptor subfamily 1 group I member 2NR1I2 O75469
1 Reference(s)
T43N2D Epidermal growth factor receptorEGFR P00533
1 Reference(s)
T15I0F Proteasome activator complex subunit 1PSME1 Q06323
1 Reference(s)
T44BWE Adiponectin receptor protein 2ADIPOR2 Q86V24
1 Reference(s)
T49TDM Matrix metalloproteinase-9MMP9 P14780
4 Reference(s)
T44LWL Transcription factor p65RELA Q04206
7 Reference(s)
T79KQO NF-kappa-B inhibitor alphaNFKBIA P25963
3 Reference(s)
T26KIE Transcription factor AP-1JUN P05412
1 Reference(s)
T23VMI Tumor necrosis factorTNF P01375
3 Reference(s)
T33OPP Interleukin-6IL6 P05231
1 Reference(s)
T24U57 E-selectinSELE P16581
1 Reference(s)
T72BXP Platelet endothelial cell adhesion moleculePECAM1 P16284
2 Reference(s)
T42EAZ Vascular endothelial growth factor AVEGFA P15692
2 Reference(s)
T88QQE Fibroblast growth factor 2FGF2 P09038
1 Reference(s)
T96OOK Signal transducer and activator of transcription 3STAT3 P40763
1 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
6 Reference(s)
T74I49 Bcl-2-like protein 1BCL2L1 Q07817
4 Reference(s)
T39YUJ Tyrosine-protein phosphatase non-receptor type 6PTPN6 P29350
1 Reference(s)
T85U8U Caspase-3CASP3 P42574
5 Reference(s)
T80OJF Interstitial collagenaseMMP1 P03956
1 Reference(s)
T80GUN 72 kDa type IV collagenaseMMP2 P08253
2 Reference(s)
T20H9F Stromelysin-1MMP3 P08254
1 Reference(s)
T95H9O Stromelysin-2MMP10 P09238
1 Reference(s)
T38T1U Caspase-8CASP8 Q14790
3 Reference(s)
T80TUC Apoptosis regulator BAXBAX Q07812
2 Reference(s)
T38OH4 Caspase-1CASP1 P29466
1 Reference(s)
T23P74 Caspase-9CASP9 P55211
2 Reference(s)
T82JWE Cellular tumor antigen p53TP53 P04637
2 Reference(s)
T08U92 Mitochondrial brown fat uncoupling protein 1UCP1 P25874
1 Reference(s)
T13WH4 Interferon-induced, double-stranded RNA-activated protein kinaseEIF2AK2 P19525
1 Reference(s)
T77FOL NeuromodulinGAP43 P17677
1 Reference(s)
T00CXT Prostaglandin G/H synthase 1PTGS1 P23219
1 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
1 Reference(s)
T27U96 Granulocyte-macrophage colony-stimulating factorCSF2 P04141
1 Reference(s)
T64BTV Interleukin-1 betaIL1B P01584
1 Reference(s)
T10HL8 Intercellular adhesion molecule 1ICAM1 P05362
2 Reference(s)
T09H2Z Nitric oxide synthase, inducibleNOS2 P35228
1 Reference(s)
T02GD4 Tumor necrosis factor ligand superfamily member 6FASLG P48023
1 Reference(s)
T10S5F Cyclin-dependent kinase 4CDK4 P11802
1 Reference(s)
T22IMH Cyclin-dependent kinase 6CDK6 Q00534
1 Reference(s)
T38BR0 G1/S-specific cyclin-D2CCND2 P30279
1 Reference(s)
T75H3W Cyclin-dependent kinase 2CDK2 P24941
1 Reference(s)
T74JJN Fatty acid synthaseFASN P49327
1 Reference(s)
T64W2K Cyclin-dependent kinase inhibitor 1CDKN1A P38936
1 Reference(s)
T93WZG G1/S-specific cyclin-D1CCND1 P24385
1 Reference(s)
T64UH1 Nitric oxide synthase, endothelialNOS3 P29474
1 Reference(s)
T75HMM Induced myeloid leukemia cell differentiation protein Mcl-1MCL1 Q07820
1 Reference(s)
T04UTZ G1/S-specific cyclin-E1CCNE1 P24864
1 Reference(s)
T80OPZ NADPH oxidase 4NOX4 Q9NPH5
1 Reference(s)
T53ES3 Protein S100-A1S100A1 P23297
1 Reference(s)
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
1 Reference(s)
T04A6O UDP-glucuronosyltransferase 1A3UGT1A3 P35503
1 Reference(s)
T50WOV ATP-dependent translocase ABCB1ABCB1 P08183
1 Reference(s)
T92BZ2 Catenin beta-1CTNNB1 P35222
1 Reference(s)
T14LSK E3 ubiquitin-protein ligase XIAPXIAP P98170
1 Reference(s)
T91OUC Mucin-5ACMUC5AC P98088
1 Reference(s)
T59IKQ Vascular cell adhesion protein 1VCAM1 P19320
1 Reference(s)
T64X48 C-X-C chemokine receptor type 4CXCR4 P61073
1 Reference(s)
T61OY3 UDP-glucuronosyltransferase 1A1UGT1A1 P22309
1 Reference(s)
T37WQE Kallikrein-5KLK5 Q9Y337
1 Reference(s)
T16DCZ Twist-related protein 1TWIST1 Q15672
1 Reference(s)
T30D9G Superoxide dismutase [Cu-Zn]SOD1 P00441
1 Reference(s)
T94AGC [F-actin]-monooxygenase MICAL1MICAL1 Q8TDZ2
1 Reference(s)
T48K08 Procathepsin LCTSL P07711
1 Reference(s)
T27S6H Pulmonary surfactant-associated protein BSFTPB P07988
1 Reference(s)
T86ROZ Heme oxygenase 1HMOX1 P09601
1 Reference(s)
T04MBA Vascular endothelial growth factor receptor 2KDR P35968
1 Reference(s)
T19BO9 Bone morphogenetic protein 4BMP4 P12644
1 Reference(s)
T34AW3 Lipopolysaccharide-binding proteinLBP P18428
1 Reference(s)

Related Compounds  (Total: 3)

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C0476
Name: Ursolic Acid
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C0653
Name: 20-Hydroxyecdysone
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C1201
Name: Butylated Hydroxytoluene