HIT-result

Target Description

Type	Detail
Target ID	T94AGC
Protein Name	[F-actin]-monooxygenase MICAL1
Uniprot ID	Q8TDZ2
Protein Name Alias	EC 1.14.13.225; Molecule interacting with CasL protein 1; MICAL-1; NEDD9-interacting protein with calponin homology and LIM domains
Gene ID	64780
Gene Symbol	MICAL1
Gene Alias	MICAL; NICAL
TTD	NA
Pfam	PF00307 ; PF12130 ; PF01494 ; PF00412
GO	0003779:actin binding 0005829:cytosol 0016174:NAD(P)H oxidase H2O2-forming activity 0016709:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 0045171:intercellular bridge 0051017:actin filament bundle assembly 1903305:regulation of regulated secretory pathway 0005737:cytoplasm 0019901:protein kinase binding 0005882:intermediate filament 0005886:plasma membrane 0007596:blood coagulation 0030496:midbody 0017124:SH3 domain binding 0001933:negative regulation of protein phosphorylation 1990026:hippocampal mossy fiber expansion 0030042:actin filament depolymerization 0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 0031267:small GTPase binding 0007165:signal transduction 0015629:actin cytoskeleton 0051015:actin filament binding 0046872:metal ion binding 0019417:sulfur oxidation 0007010:cytoskeleton organization 0071949:FAD binding
PDB	2CO8 ; 5LPN ; 2DK9 ; 5LE0 ; 1WYL ; 6KU0
Drugbank	NA
KEGG	hsa:64780

Type

Detail

Target ID

T94AGC

Protein Name

[F-actin]-monooxygenase MICAL1

Uniprot ID

Q8TDZ2

Protein Name Alias

EC 1.14.13.225; Molecule interacting with CasL protein 1; MICAL-1; NEDD9-interacting protein with calponin homology and LIM domains

Gene ID

64780

Gene Symbol

MICAL1

Gene Alias

MICAL; NICAL

TTD

Pfam

PF00307 ; PF12130 ; PF01494 ; PF00412

0003779:actin binding

0005829:cytosol

0016174:NAD(P)H oxidase H2O2-forming activity

0016709:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

0045171:intercellular bridge

0051017:actin filament bundle assembly

1903305:regulation of regulated secretory pathway

0005737:cytoplasm

0019901:protein kinase binding

0005882:intermediate filament

0005886:plasma membrane

0007596:blood coagulation

0030496:midbody

0017124:SH3 domain binding

0001933:negative regulation of protein phosphorylation

1990026:hippocampal mossy fiber expansion

0030042:actin filament depolymerization

0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

0031267:small GTPase binding

0007165:signal transduction

0015629:actin cytoskeleton

0051015:actin filament binding

0046872:metal ion binding

0019417:sulfur oxidation

0007010:cytoskeleton organization

0071949:FAD binding

PDB

2CO8 ; 5LPN ; 2DK9 ; 5LE0 ; 1WYL ; 6KU0

Drugbank

KEGG

hsa:64780

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0336	Qin Jiao	秦艽	large-leaved gentian	Gentiana macrophylla
H0296	Niu Teng	牛藤	twotooth achyranthes root	Achyranthes bidentata
H0500	Can Yong	蚕蛹	Silkworm chrysalis	Bombyx mori
H1134	Bai Jiang Can	白僵蚕	Silkworm larva	Bombyx mori
H0261	Mo Yao	没药	Myrrh	Commiphora myrrha
H0297	Niu Xi	牛膝	Twotooth achyranthes	Achyranthes bidentata
H0490	Can Jian	蚕茧	Silk cocoon	Bombyx mori
H0765	Chi Dou	赤豆	Assuki bean	Vigna angularis
H0495	Can Sha	蚕砂	Silkworm excrement	Bombyx mori
H0793	Zhao Shan Bai	照山白	Manchurian rhododendron	Rhododendron micranthum
H0254	Mian Ma Guan Zhong	绵马贯众	Male fern rhizome	Rhizoma dryopteris crassirhizomae
H0498	Si Ji Cai	四季菜	Ghostplant wormwood	Artemisia lactiflora
H0169	Lou Lu	漏芦	Uniflower swisscentaury	Rhaponticum uniflorum
H0782	Zao Xiu	蚤休	NA	Paris polyphylla
H0051	Jin Guo Lan	金果榄	Hairystalk tinospora	Tinospora capillipes
H0260	Mo Xiang	没香	Myrrh	Commiphora myrrha
H0322	Qi Ye Yi Zhi Hua	七叶一枝花	rhizome of verticillate paris	Paris polyphylla
H0476	Can E	蚕蛾	Silkworm	Bombyx mori
H0871	Chuan Duan	川断	Teasels	Dipsacus asper
H0337	Qin Jiao Hua	秦艽花	large-leaved gentian flower	Gentiana straminea
H0820	Chong Lou	重楼	Paris root	Rhizoma paridis
H0696	Ya Jiao Ai	鸭脚艾	Ghostplant wormwood	Artemisia lactiflora

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 22)