Target Description
| Type | Detail |
|---|---|
| Target ID | T37WQE |
| Protein Name | Kallikrein-5 |
| Uniprot ID |
Q9Y337 |
| Protein Name Alias | EC 3.4.21.-; Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme |
| Gene ID |
25818 |
| Gene Symbol | KLK5 |
| Gene Alias | SCTE |
| TTD | T11808: Patented target |
| Pfam | PF00089 |
| GO |
0030141:secretory granule
0022617:extracellular matrix disassembly 0097209:epidermal lamellar body 0008544:epidermis development 0097186:amelogenesis 0008236:serine-type peptidase activity 0045745:positive regulation of G protein-coupled receptor signaling pathway 0070268:cornification 0005615:extracellular space 0004252:serine-type endopeptidase activity 0005829:cytosol 0002803:positive regulation of antibacterial peptide production 0005576:extracellular region 0008233:peptidase activity |
| PDB | 2PSX ; 6QFE ; 2PSY |
| Drugbank | NA |
| KEGG | hsa:25818 |
Related Compounds (Total: 3)
Related Herbs (Total: 102)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0494 | Shui Yang Mei Gen | 水杨梅根 | Japanese avens root | Geum japonicum |
| H0289 | Niu Bang Zi | 牛蒡子 | Great burdock fruit | Arctium lappa |
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H1109 | Bai Hua She She Cao | 白花蛇舌草 | Spreading hedyitis | Oldenlandia diffusa |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H0193 | Ma Bian Cao | 马鞭草 | European verbena | Verbena officinalis |
| H1203 | Hu Ji Sheng | 槲寄生 | Colored mistletoe | Viscum coloratum |
| H0063 | Jin Ye Zi | 金叶子 | Yunnan craibiodendron | Craibiodendron yunnanese |
| H0016 | Ji Xue Cao | 积雪草 | Asiatic pennywort | Centella asiatica |
| H1049 | Feng Xiang Zhi Chou Gao | 枫香脂稠膏 | NA | Liquidambar formosana |
| H0365 | Rou Dou Kou | 肉豆蔻 | Common nutmeg | Myristica fragrans |
| H1127 | Guang Shan Zha | 广山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0308 | Pi Ba Ren | 枇杷仁 | NA | Eriobotrya japonica |
| H0844 | Zi Cao | 紫草 | Redroot gromwell | Lithospermum erythrorhizon |
| H0693 | Xue Xie | 血蝎 | Dragon's blood | Daemonorops draco |
| H0701 | Yan Bai | 岩柏 | NA | Juniperus formosana |
| H0064 | Jin Yin Hua | 金银花 | Japanese honeysuckle | Lonicera japonica |
| H0747 | An Xi Xiang | 安息香 | Sumatra snowbel | Styrax benzoin |
| H0493 | Shui Yang Mei | 水杨梅 | Japanese avens | Geum japonicum |
| H0300 | Nv Zhen Zi | 女贞子 | Glossy privet fruit | Ligustrum lucidum |
| H1047 | Feng Xiang Ye | 枫香叶 | NA | Liquidambar formosana |
| H0632 | Xia Ku Cao | 夏枯草 | Common selfheal | Prunella vulgaris |
| H1004 | Bai Cha | 白茶 | White tea | Camellia sinensis |
| H1053 | Fu Ling | 茯苓 | Indian bread | Wolfiporia cocos |
| H0470 | Shi Ye | 柿叶 | Persimmon leaf | Diospyros kaki |
| H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H1138 | Bai Jiang Cao | 败酱草 | All - grass of dahurian patrinia | Thlaspi arvense |
| H0422 | Shan Zha Tan | 山楂炭 | Chinese hawthorn | Crataegus pinnatifida |
| H0419 | Shan Zha | 山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0020 | Ji Yan Cao | 鸡眼草 | Striate kummerowia | Kummerowia striata |
| H0902 | Chun Pi | 椿皮 | Ailanthus bark, tree of heaven bark | Ailanthi cortex |
| H0229 | Mao Da Ding Cao | 毛大丁草 | Pilose gerbera | Gerbera piloselloides |
| H1099 | Gou Teng | 钩藤 | Sharpleaf gambirplant | Uncaria rhynchophylla |
| H1097 | Gong Ding Xiang | 公丁香 | NA | Syzygium aromaticum |
| H0854 | Zi Wei Gen Pi | 紫葳根皮 | NA | Campsis grandiflora |
| H0855 | Chuan Bei Mu | 川贝母 | Fritillaria unibracteata | Fritillaria cirrhosa |
| H0565 | Tu Bie Chong | 土鳖虫 | Cockroach | Eupolyphaga sinensis |
| H0591 | Wei Ling Cai | 委陵菜 | Chinese cinquefoil | Potentilla chinensis |
| H0085 | Jiu Yu Rou | 酒萸肉 | Asiatic cornelian cherry | Cornus officinalis |
| H0420 | Shan Zha Chou Gao | 山楂稠膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0519 | Suo Yang | 锁阳 | Songaria cynomorium | Cynomorium songaricum |
| H0169 | Lou Lu | 漏芦 | Uniflower swisscentaury | Rhaponticum uniflorum |
| H0427 | Shan Zhu Yu | 山茱萸 | Asiatic cornelian cherry | Cornus officinalis |
| H1186 | Hong Gen Cao | 红根草 | Hispid sage | Salvia prionitis |
| H0072 | Jing Jie | 荆芥 | Fineleaf schizonepeta | Schizonepeta tenuifolia |
| H0577 | Tu Niu Xi | 土牛膝 | Common achyranthes | Achyranthes aspera |
| H0801 | Chong Bai La | 虫白蜡 | Cera chinensis wax | Ericerus pela |
| H0496 | Shui Ze Lan | 水泽兰 | NA | Lycopus lucidus |
| H1128 | Bai Jiang | 败酱 | Whiteflower patrinia | Patrinia villosa |
| H0990 | Ding Xiang | 丁香 | Clove tree | Syzygium aromaticum |
| H1017 | Du Zhong Ye | 杜仲叶 | Eucommia leaf | Eucommia ulmoides |
| H0074 | Jing Jie Tan | 荆芥炭 | NA | Schizonepetae herba |
| H0656 | Xiao Bo Gen | 小檗根 | Barberry root | Berberis julianae |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0989 | Ding Kui Cao | 丁葵草 | Herb of twinleaf zornia | Kummerowia striata |
| H0237 | Mei Gui Hua | 玫瑰花 | Rugose rose flower | Rosa rugosa |
| H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0177 | Lu Lu Tong | 路路通 | Beautiful sweetgum | Liquidambar formosana |
| H0065 | Jin Yin Hua Ti Qu Ye | 金银花提取液 | Japanese honeysuckle | Lonicera japonica |
| H0638 | Xiang Bei | 象贝 | Fritillaria | Fritillaria thunbergii |
| H0354 | Ren Dong Teng | 忍冬藤 | Japanese honeysuckle vine | Lonicera japonica |
| H0216 | Man Jing Ye | 蔓荆叶 | Threeleaf chastetree leaf | Vitex trifolia |
| H0361 | Ren Zi Cao | 人字草 | Herb of twinleaf zornia | Kummerowia striata |
| H0871 | Chuan Duan | 川断 | Teasels | Dipsacus asper |
| H0320 | Qi Shu Gen | 漆树根 | true lacquertree root | Toxicodendron succedaneum |
| H0068 | Jin Ying Zi Rou | 金樱子肉 | Cherokee rose seed | Rosa laevigata |
| H0967 | Di Er Cao | 地耳草 | Japanese stJohn’swort | Hypericum japonicum |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0570 | Tu Fu Ling | 土茯苓 | Glabrous greenbrier | Smilax glabra |
| H0859 | Chuan Bei Mu Liu Jin Gao | 川贝母流浸膏 | Fritillaria unibracteata | Fritillaria cirrhosa |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H1015 | Du Zhong | 杜仲 | Eucommia | Eucommia ulmoides |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H0733 | Ye Shan Zha | 野山楂 | nippon bawthorn | Crataegus pinnatifida |
| H0073 | Jing Jie Sui | 荆芥穗 | NA | Schizonepetae spica |
| H0614 | Wu Zhao Long | 五爪龙 | Cairo morningglory | Ipomoea cairica |
| H0217 | Man Jing Zi | 蔓荆子 | Threeleaf chastetree fruit | Vitex trifolia |
| H0646 | Xiang Qing Lan | 香青兰 | Dragonhead | Dracocephalum moldavica |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H0715 | Che Qian Zi | 车前子 | seed of asiatic pantain | Plantago asiatica |
| H0060 | Jin Si Ku Lian | 金丝苦楝 | NA | Cardiospermum halicacabum |
| H0963 | Dao Kou Cao | 倒扣草 | NA | Achyranthes aspera |
| H0226 | Man Yue Mei | 蔓越莓 | Cranberry | Vaccinium oxycoccos |
| H0327 | Qian Li Guang | 千里光 | Climbing groundsel | Senecio scandens |
| H0158 | Liu Ling Ju | 六棱菊 | NA | Laggera alata |
| H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0053 | Jin Lian Hua | 金莲花 | Chinese globeflower | Trollius chinensis |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0067 | Jin Ying Zi | 金樱子 | Cherokee rose seed | Rosa laevigata |
| H1211 | Bai Mei | 白眉 | pilose gerbera herb | Gerbera piloselloides |
| H0421 | Shan Zha Qing Gao | 山楂清膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0423 | Shan Zha Ye | 山楂叶 | NA | Crataegi folium |
| H0087 | Ju Gu Ye | 枸骨叶 | FOLIUM iLICIS cORNUTAE | Ilex cornuta |
| H0622 | Xi He Liu | 西河柳 | Chinese tamarisk twig | Cacumen tamaricis |
| H0069 | Jin Ying Zi Ti Qu Ye | 金樱子提取液 | Cherokee rose seed | Rosa laevigata |
| H0139 | Lian Qiao | 连翘 | Weeping forsythia | Forsythia suspensa |
| H0503 | Song Jie | 松节 | Knotty pine wood, pine nodular branch | Lignum pini nodi |
| H0894 | Chuan Xu Duan | 川续断 | Himalayan teasel | Dipsacus asperoides |
| H0453 | Shi Di | 柿蒂 | Persimmon persistent calyx | Diospyros kaki |
| H0637 | Cha Ye | 茶叶 | Common tea | Camellia sinensis |
| H1016 | Du Zhong Tan | 杜仲炭 | Eucommia | Eucommia ulmoides |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |